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| Product | Description | |
|---|---|---|
| gelatinase A | A secreted endopeptidase in peptidase family M10 (interstitial collagenase family), but possessing an additional fibronectin-like domain. Group: Enzymes. Synonyms: 72-kDa gelatinase; matrix metalloproteinase 2; type IV collagenase (ambiguous); 3/4 collagenase (obsolete); matrix metalloproteinase 5 (obsolete); 72 kDa gelatinase type A; collagenase IV (ambiguous); collagenase type IV (ambiguous); MMP 2; type IV collagen metalloproteinase (ambiguous); type IV collagenase/gelatinase (ambiguous). Enzyme Commission Number: EC 3.4.24.24. CAS No. 146480-35-5. Matrix Metalloproteinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4305; gelatinase A; EC 3.4.24.24; 146480-35-5; 72-kDa gelatinase; matrix metalloproteinase 2; type IV collagenase (ambiguous); 3/4 collagenase (obsolete); matrix metalloproteinase 5 (obsolete); 72 kDa gelatinase type A; collagenase IV (ambiguous); collagenase type IV (ambiguous); MMP 2; type IV collagen metalloproteinase (ambiguous); type IV collagenase/gelatinase (ambiguous). Cat No: EXWM-4305. |  |
| gelatinase B | Similar to gelatinase A, but possesses a further domain. In peptidase family M10 (interstitial collagenase family). Group: Enzymes. Synonyms: 92-kDa gelatinase; matrix metalloproteinase 9; type V collagenase; 92-kDa type IV collagenase; macrophage gelatinase; 95 kDa type IV collagenase/gelatinase; collagenase IV (ambiguous); collagenase type IV (ambiguous); gelatinase MMP 9; MMP 9; type IV collagen metalloproteinase (ambiguous). Enzyme Commission Number: EC 3.4.24.35. CAS No. 146480-36-6. Matrix Metalloproteinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4317; gelatinase B; EC 3.4.24.35; 146480-36-6; 92-kDa gelatinase; matrix metalloproteinase 9; type V collagenase; 92-kDa type IV collagenase; macrophage gelatinase; 95 kDa type IV collagenase/gelatinase; collagenase IV (ambiguous); collagenase type IV (ambiguous); gelatinase MMP 9; MMP 9; type IV collagen metalloproteinase (ambiguous). Cat No: EXWM-4317. | |
| Gelatinase B, pro- | Gelatinase B, pro-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 92 KDA GELATINASE, PROENZYME;MATRIX METALLOPROTEINASE, PROENZYME;MATRIX METALLOPROTEINASE 9, PRO-;EC 3.4.24.35;HUMAN PRO-MMP-9;GELATINASE B, PROENZYME;TYPE IV COLLAGENASE, PROENZYME;MMP-9, PRO-. Product Category: Heterocyclic Organic Compound. CAS No. 152787-66-1. Product ID: ACM152787661. Alfa Chemistry ISO 9001:2015 Certified. |  |
| (2E)-3-(3-Pyridinyl)-2-propenoic Acid | (2E)-3-(3-Pyridinyl)-2-propenoic Acid is a useful synthetic intermediate. It is used to synthesize aminomethyl benzimidazoles as inhibitors of gelatinase B. It can also be used to prepare aminopyridines as antibacterial enoyl ACP reductase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 19337-97-4. Pack Sizes: 10g, 25g. Molecular Formula: C8H7NO2, Molecular Weight: 149.15. US Biological Life Sciences. |  Worldwide |
| (2E)-3-(3-Pyridinyl)-2-propenoic Acid-d4 | (2E)-3-(3-Pyridinyl)-2-propenoic Acid-d4 is labelled (2E)-3-(3-Pyridinyl)-2-propenoic Acid (P991835) which is used to synthesize aminomethyl benzimidazoles as inhibitors of gelatinase B. It can also be used to prepare aminopyridines as antibacterial enoyl ACP reductase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C8H3D4NO2, Molecular Weight: 153.169999999999. US Biological Life Sciences. | Worldwide |
| 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid | 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid is a broad spectrum inhibitor of MMP-1 and MMP-8 (collgenases, IC50=1.0μM), MMP-9 (granulocyte gelatinase, IC50=50μM), and MMP-3 (skin fibroblast stromelysin, IC50=50μM). Synonyms: 4-Abz-Gly-Pro-D-Leu-D-Ala-NHOH; 4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid; MMP Inhibitor I. Grade: 95%. CAS No. 124168-73-6. Molecular formula: C23H34N6O6. Mole weight: 490.55. |  |
| 72 kDa type IV collagenase (560-568) | 72 kDa type IV collagenase (560-568) is amino acids 560 to 568 fragment of 72 kDa type IV collagenase. 72 kDa type IV collagenase is a ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. Synonyms: 72 kDa gelatinase (560-568); Matrix metalloproteinase-2 (560-568). | |
| Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt | It is used as a substrate in a rapid, sensitive, continuous spectrophotometric assay for vertebrate collagenase, gelatinase A, and gelatinase B. Synonyms: Glycine, 1-acetyl-L-prolyl-L-leucylglycyl-2-mercapto-4-methylpentanoyl-L-leucyl-, ethyl ester. CAS No. 98992-65-5. Molecular formula: C31H53N5O8S. Mole weight: 655.85. | |
| Ambuic acid | Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species. Antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP). Synonyms: (+)-Ambuic acid; (2E,5R,6R,7R,8E,10E)-2-Methyl-5,9-carbonyl-5,6-epoxy-7-hydroxy-8-(hydroxymethyl)-2,8,10-hexadecatrienoic acid. Grade: ≥95%. CAS No. 340774-69-8. Molecular formula: C19H26O6. Mole weight: 350.41. | |
| BE-16627B | BE-16627B is a novel metalloproteinase (MP) inhibitor isolated from Streptomyces sp. BE16627B selectively inhibited MPs such as human stromelysin and 92 kD gelatinase. Synonyms: BE 16627B; BE16627B; L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine; N-[1,3-Dihydroxy-2-({1-hydroxy-2-[2-hydroxy-2-(hydroxyimino)ethyl]-4-methylpentylidene}amino)propylidene]valine. Grade: >98%. CAS No. 137530-61-1. Molecular formula: C31H35Cl2F6N3O3. Mole weight: 375.42. | |
| Matrix Metalloproteinase-2 from Human, Recombinant | Matrix metalloproteinases are members of a unique family of proteolytic enzymes that have a zinc ion at their active sites and can degrade collagens, elastin and other components of the extracellular matrix (ECM). These enzymes are present in normal healthy individuals and have been shown to have an important role in processes such as wound healing, pregnancy, and bone resorption. However, overexpression and activation of MMPs have been linked with a range of pathological processes and disease states involved in the breakdown and remodeling of the ECM. Such diseases include tumor invasion and metastasis, rheumatoid arthritis, periodontal disease and vascular processe... does not interfere with activation. may contain up to 10% timp proteins. during storage, a small portion (less than 10%) of the enzyme may also become activated. Group: Enzymes. Synonyms: 72 kDa Gelatinase; Matrix Metalloproteinase 2; Gelatinase A; EC 3.4.24.24; type IV collagenase; 3/4 collagenase; matrix metalloproteinase 5; 72 kDa gelatinase type A; collagenase IV; collagenase type IV; MMP 2; type IV collagen metalloproteinase; type IV collagenase/gelatinase. Enzyme Commission Number: EC 3.4.24.24. CAS No. 146480-35-5. Purity: >90% by SDS-PAGE. Matrix Metalloproteinase. Mole weight: 72 kDa. Storage: < -70°C; Avoid freeze/thaw. Form: Liquid. Source: CHO Cells. Spe | |
| Matrix Metalloproteinase-9 from Human, Recombinant | Matrix metalloproteinases are members of a unique family of proteolytic enzymes that have a zinc ion at their active sites and can degrade collagens, elastin and other components of the extracellular matrix (ECM). These enzymes are present in normal healthy individuals and have been shown to have an important role in processes such as wound healing, pregnancy, and bone resorption. However, overexpression and activation of MMPs have been linked with a range of pathological processes and disease states involved in the breakdown and remodeling of the ECM. Such diseases include tumor invasion and metastasis, rheumatoid arthritis, periodontal disease and vascular processe...(less than 10%) of the enzyme may also become activated. requires activation prior to use. a simple activation protocol is included. Applications: Immunoblotting (1 ug protein/lane) substrate cleavage assay (1 ug protein/lane) zymography (1 ug protein/lane). Group: Enzymes. Synonyms: Gelatinase B; EC 3.4.24.35; 92-kDa gelatinase; matrix metalloproteinase 9; type V collagenase; 92-kDa type IV collagenase; macrophage gelatinase; 95 kDa type IV collagenase/gelatinase; collagenase IV; collagenase type IV; gelatinase MMP 9; MMP 9; type IV collagen metalloproteinase. Enzyme Commission Number: EC 3.4.24.35. CAS No. 146480-36-6. Purity: >90% by SDS-PAGE. Matrix Metalloprotei | |
| Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 | Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2, the FRET substrate, is hydrolyzed 60 times more rapidly by stromelysin 1 (MMP-3) (kcat/Km= 59400 M-1s-1) than by interstitial collagenase (MMP-1). However, it shows little discrimination between MMP-3, gelatinase A (MMP-2) (kcat/Km= 54000 M-1s-1), and gelatinase B (MMP-9) (kcat/Km = 55300 M-1s-1). This fluorogenic substrate is digested by Metalloelastase (MMP-12) with a kcat/Km of 243000 M-1s-1. Synonyms: NFF-2; 7-Methoxycoumarin-4-acetyl-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-(2,4-dinitrophenyl)Lys amide; N2-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-tyrosyl-L-alanyl-L-norvalyl-L-tryptophyl-L-methionyl-N6-(2,4-dinitrophenyl)-L-lysinamide. Grade: ≥95%. CAS No. 158584-08-8. Molecular formula: C79H105N19O19S. Mole weight: 1656.86. | |
| Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 | Mca-KPLGL-Dpa-AR-NH2 is an N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH2 with a Lys yields a fluorogenic peptide with improved substrate properties. Compared with Mca-PLGL-Dpa-AR-NH2, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate Mca-KPLGL-Dpa-AR-NH2 for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased by 2-9 times and 3 times, respectively, while those for gelatinases and matrilysin remain equally high. Synonyms: L-Argininamide, N2-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-; N2-[2-(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-L-argininamide; MMPs substrate Fluorogenic. Grade: ≥95%. CAS No. 720710-69-0. Molecular formula: C55H80N16O16. Mole weight: 1221.32. | |
| MMP-2/MMP-9 Substrate I, Fluorogenic | A fluorogenic substrate for both the 72 kDa human fibroblast gelatinase (HFG; MMP-2) and the 92 kDa human neutrophil gelatinase (HNG; MMP-9). Group: Fluorescence/luminescence spectroscopy. |  |
| MMP-2/MMP-9 Substrate II | An exceptional thiopeptide that is used as a substrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B). Group: Fluorescence/luminescence spectroscopy. | |
| MMP-2 Substrate, Fluorogenic | A quenched fluorescence substrate for MMP-2 (gelatinase A; kcat/Km = 3.97 x 10? M?¹s?¹). Group: Fluorescence/luminescence spectroscopy. | |
| pepsin B | Formed from pig pepsinogen B. In peptidase family A1 (pepsin A family). Group: Enzymes. Synonyms: parapepsin I; pig gelatinase. Enzyme Commission Number: EC 3.4.23.2. CAS No. 9025-48-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4257; pepsin B; EC 3.4.23.2; 9025-48-3; parapepsin I; pig gelatinase. Cat No: EXWM-4257. | |
| SB-3CT | SB-3CT is a potent and competitive matrix metalloproteinase MMP-2 and MMP-9 inhibitor with Ki values of 13.9 and 600 nM, respectively. SB-3CT has high selectivity for gelatinases. SB-3CT shows blood-brain barrier permeability and has neuroprotective effects and anticancer activity[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 292605-14-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12354. |  |
| TAPI-0 - CAS 143457-40-3 | TAPI-0, CAS 143457-40-3, is a hydroxamate-based inhibitor of collagenase, gelatinase, and TACE (TNF-? converting enzyme/ADAM17; IC?? = 100 nM). Group: Fluorescence/luminescence spectroscopy. | |
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