Geranylgeranyl Transferase Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
AZD-3409 Quick inquiry Where to buy Suppliers range | AZD-3409 is a potent prenyl transferase inhibitor. AZD-3409 showed higher potency than lonafarnib. AZD3409 inhibits farnesylation to a higher extent than geranylgeranylation. AZD3409 might be active in gefitinib-resistant breast carcinoma. Synonyms: AZD-3409; AZD 3409; AZD3409. Grades: 98%. CAS No. 345915-10-8. Molecular formula: C34H41FN4O4S2. Mole weight: 652.844. | |
FTase Inhibitor I Quick inquiry Where to buy Suppliers range | FTase inhibitor I is a potent and selective farnesyltransferase (FTase) inhibitor with an IC50 of 21 nM, which is 30-fold higher for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM). Synonyms: Farnesyltransferase Inhibitor I; B581; N-[(2S)-2-[[(2R)-2-amino-3-mercaptopropyl]amino]-3-methylbutyl]-L-phenylalanyl-L-methionine. Grades: ≥95%. CAS No. 149759-96-6. Molecular formula: C22H38N4O3S2. Mole weight: 470.69. | |
FTase Inhibitor II Quick inquiry Where to buy Suppliers range | FTase Inhibitor II is a cell-permeable analog of farnesyl pyrophosphate (FPP) that potently inhibits FTase with an IC50 of 50-75 nM, and it does not inhibit geranylgeranyl transferase at similar concentrations (IC50 > 100 μM). FTase Inhibitor II is a possible cancer therapeutic agent. Synonyms: Farnesyltransferase Inhibitor II; FTI-II; N-[4-[[(2R)-2-amino-3-mercapto-1-oxopropyl]amino]benzoyl]-L-methionine. Grades: ≥80%. CAS No. 156707-43-6. Molecular formula: C15H21N3O4S2. Mole weight: 371.47. | |
GGTI 2133 trifluoroacetate salt Quick inquiry Where to buy Suppliers range | GGTI 2133 is a peptidomimetic inhibitor of geranylgeranyl transferase type I (GGTase I) with an IC50 value of 38 nM, whch is 140-fold selective for GGTase I over farnesyltransferase (IC50 = 5,400 nM). Synonyms: N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-L-leucine, 2,2,2-trifluoroacetate salt. Grades: ≥95%. CAS No. 1217480-14-2. Molecular formula: C27H28N4O3·xCF3COOH. Mole weight: 456.54. | |
GGTI-2166 Quick inquiry Where to buy Suppliers range | GGTI-2166 is a geranylgeranyl transferase I inhibitor. GGTI-2166 inhibit the pOC formation induced by RANKL or TNF-alpha in cultures of both mouse marrow-derived macrophage-colony-stimulating factor (M-CSF) dependent monocytes (MD cells) and the mouse monocyte cell line RAW 264.7 (RAW cells). GGTI-2166 inhibited TRAP activity induced by RANKL or TNF-alpha in both cell cultures and prevented the incorporation of [3H]all-trans geranylgeraniol into prenylated proteins in RAW cells. Synonyms: GGTI2166; GGTI2166. Grades: 98%. CAS No. 478908-51-9. Molecular formula: C25H30N4O3. Mole weight: 434.53. | |
Psoromic acid Quick inquiry Where to buy Suppliers range | Psoromic acid is a selective inhibitor of Rab geranylgeranyl transferase and P. falciparum fatty acid synthesis (FAS) II enzymes. Synonyms: 10-formyl-9-hydroxy-3-methoxy-4,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-1-carboxylic acid; NSC 92186; Parellic Acid; Psoromsaeure; Sulcatic acid; Sqamaric. Grades: ≥95%. CAS No. 7299-11-8. Molecular formula: C18H14O8. Mole weight: 358.30. |