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| Product | Description | |
|---|---|---|
| Ginkgolide B | Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists. Group: Biochemicals. Alternative Names: (1R, 3S, 3aS, 4R, 6aR, 7aR, 7bR, 8S, 10aS, 11R, 11aR) -3- (1, 1-Dimethylethyl) hexahydro-4, 7b, 11-trihydroxy-8-methyl-9H-1, 7a- (epoxymethano) -1H, 6aH-cyclopenta[c]furo[2, 3-b]furo[3', 2': 3, 4]cyclopenta[1, 2-d]furan-5, 9, 12 (4H) -trione; BN 52021. Grades: Highly Purified. CAS No. 15291-77-7. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Ginkgolide B | Ginkgolide B (BN-52021), an important active terpenoid from Ginkgo biloba leaves, is reported to increase cell viability and decrease cell apoptosis.IC50 value:Target:In vitro: Ginkgolide B (0.2 or 0.4 μg/ml) was added to the culture medium in vitro led to increases in cell viability and decreases in the number of hippocampal cells undergoing AAPH-induced apoptosis. Ginkgolide B caused a dose-related protection against dysrhythmias; the antiarrhythmic effect of ginkgolide B was comparable to that of diltiazem and superior to the activity of metoprolol. Ginkgolide B can presumably prevent the re-entry mechanism involved in the development of ischemia-induced rhythm disturbances.In vivo: Oral administration of ginkgolide B (2 mg/kg/day, p.o.) caused a significant increase in cell viability and a highly significant decrease in the numbers of both spontaneously occurring and AAPH-induced apoptoses. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Deoxyginkgolide C. Product Category: Inhibitors. Appearance: White powder. CAS No. 15291-77-7. Molecular formula: C20H24O10. Mole weight: 424.4. Purity: 0.98. IUPACName: (1R,3R,6R,7S,8S,10R,11R,12R,13S,16S,17R)-8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione. Canonical SMILES: C[C@@H]1C(=O)O[C@@H]2[C@]1([C@@]34C(=O)O[C@H]5[C@]3([C@H]2O)[C@@]6([C@@H](C5)C(C)(C) |  |
| Ginkgolide B | Ginkgolide B (BN-52021), a terpene lactone, is a potent platelet activating factor antagonist. Ginkgolide B protects endothelial cells via the activation of PXR from injuries induced by xeno- and endobiotics. Ginkgolide B can pass through the brain-blood barrier. Ginkgolide B has anti-oxidant, anti-inflammatory, anti-tumor, and anti- apoptotic activity. Ginkgolide B has marked neuroprotective effects against ischemia-induced impairments [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: BN-52021. CAS No. 15291-77-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0784. |  |
| Ginkgolide B | Ginkgolide B is a PAFR antagonist with an IC50 of 3.6 μM. Ginkgolide B is a bioactive diterpenoid trilactone derived from Ginkgo biloba leaves, known for its potent platelet-activating factor (PAF) antagonism. It has a complex structure with multiple chiral centers and exhibits significant neuroprotective and cerebrovascular benefits. These properties make it a promising candidate for treating neurodegenerative diseases, inflammation, and conditions related to cerebral blood flow. Uses: Fibrinolytic agents. Synonyms: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; 5H-Dicyclopenta[b,c]furan-3,5a(6H)-diacetic acid, 6-tert-butyl-3a-carboxyhexahydro-α5a,1,2,3,5,8-hexahydroxy-α3-methyl-, tri-γ-lactone; Ginkgolide A, 1-hydroxy-, (1β)-; 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-, [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11β,11aR*)]-; Bilobalide B; BN 52021; BN 52051; Ginkgolides, ginkgolide B. Grade: >98%. CAS No. 15291-77-7. Molecular formula: C20H24O10. Mole weight: 424.40. |  |
| Ginkgolide B from Ginkgo biloba leaves | ?90% (HPLC). Group: Herbal medicinal products standards. |  |
| Ginkgolide A from Ginkgo biloba leaves | analytical standard, ?90% (HPLC). Group: Herbal medicinal products standards. | |
| 3-[4- (Bromomethyl) phenyl]-3- (trifluoromethyl) diazirine | 3-[4- (Bromomethyl) phenyl]-3- (trifluoromethyl) diazirine is used as a reactant in the synthetic preparation of ginkgolide derivatives incorporating fluorescent and photoactivatable groups for photolabeling studies. Group: Biochemicals. Grades: Highly Purified. CAS No. 92367-11-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C9H6BrF3N2, Molecular Weight: 279.06. US Biological Life Sciences. | Worldwide |
| Ginkgolide A | Ginkgolide A (BN-52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist. Uses: Scientific research. Group: Natural products. Alternative Names: BN-52020. CAS No. 15291-75-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0355. | |
| Ginkgolide A | Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist with a Ki of 14.5 μM. Synonyms: (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-3-(1,1-Dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-, [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11aS*)]-; [1R-(1α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11aS*)]-3-(1,1-Dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; Bilobalide A; BN 52020. Grade: >98%. CAS No. 15291-75-5. Molecular formula: C20H24O9. Mole weight: 408.40. | |
| Ginkgolide C | Ginkgolide C is a bioactive diterpenoid trilactone compound derived from the leaves of the Ginkgo biloba tree. Similar to its counterparts Ginkgolide A and Ginkgolide B, it is characterized by its unique trilactone structure with multiple chiral centers, contributing to its diverse pharmacological properties. Ginkgolide C is known for its potent antagonistic effects on platelet-activating factor (PAF), making it a promising candidate for treating inflammatory and allergic conditions. Additionally, it has been studied for its neuroprotective effects, particularly in the context of neurodegenerative diseases and cerebral ischemia. Synonyms: (1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-3-(1,1-Dimethylethyl)hexahydro-2,4,7b,11-tetrahydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione; 5H-Dicyclopenta[b,c]furan-3,5a(6H)-diacetic acid, 6-tert-butyl-3a-carboxyhexahydro-α5a,1,2,3,5,7,8-heptahydroxy-α3-methyl-, tri-γ-lactone; Ginkgolide A, 1,7-dihydroxy-, (1β,7β)-; 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-2,4,7b,11-tetrahydroxy-8-methyl-, [1R-(1α,2α,3β,3aS*,4β,6aα,7aα,7bα,8α,10aα,11α,11aR*)]-; BN 52022. Grade: >98%. CAS No. 15291-76-6. Molecular formula: C20H24O11. Mole weigh | |
| Ginkgolide C | Ginkgolide C is a flavone isolated from Ginkgo biloba leaves, possessing multiple biological functions, such as decreasing platelet aggregation and ameliorating Alzheimer disease. Uses: Scientific research. Group: Natural products. Alternative Names: BN-52022. CAS No. 15291-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0785. | |
| Ginkgolide J | Ginkgolide J. Group: Biochemicals. Grades: Highly Purified. CAS No. 107438-79-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H24O10. US Biological Life Sciences. | Worldwide |
| Ginkgolide K | Ginkgolide K is extracted from the leaves of Ginkgo biloba L. It promotes angiogenesis after ischemia stroke and promotes astrocyte migration and proliferation after oxygen-glucose deprivation. It improves nerve injury after cerebral ischemia-reperfusion and inhibits PAF-induced platelet aggregation. It also can promote the clearance of A53T mutation alpha-synuclein in SH-SY5Y cells and shows anti- Parkinson's disease activity. It shows neuroprotective effect and anti-oxidative stress on ischemic stroke. Synonyms: 9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)-2,3,10a,11-tetrahydro-4,11-dihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aS,10aR,11R,11aR)-. Grade: 97.5%. CAS No. 153355-70-5. Molecular formula: C20H22O9. Mole weight: 406.38. | |
| levopimaradiene synthase | In Ginkgo, the enzyme catalyses the initial cyclization step in the biosynthesis of ginkgolides, a structurally unique family of diterpenoids that are highly specific platelet-activating-factor receptor antagonists. Levopimaradiene is widely distributed in higher plants. In some species the enzyme also forms abietadiene, palustradiene, and neoabietadiene. Group: Enzymes. Synonyms: PtTPS-LAS; LPS; copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]. Enzyme Commission Number: EC 4.2.3.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5190; levopimaradiene synthase; EC 4.2.3.32; PtTPS-LAS; LPS; copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]. Cat No: EXWM-5190. |  |
| Ginkgolide A | Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists. Group: Biochemicals. Alternative Names: (1R, 3S, 3aS, 4R, 6aR, 7aR, 7bR, 8S, 10aS, 11aS) -3- (1, 1-Dimethylethyl) hexahydro-4, 7b-dihydroxy-8-methyl-9H-1, 7a- (epoxymethano) -1H, 6aH-cyclopenta[c]furo[2, 3-b]furo[3', 2': 3, 4]cyclopenta[1, 2-d]furan-5, 9, 12 (4H) -trione; BN 52020. Grades: Highly Purified. CAS No. 15291-75-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Ginkgolide C | Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists. Group: Biochemicals. Alternative Names: (1S, 2R, 3S, 3aS, 4R, 6aR, 7aR, 7bR, 8S, 10aS, 11R, 11aR) -3- (1, 1-Dimethylethyl) hexahydro-2, 4, 7b, 11-tetrahydroxy-8-methyl-9H-1, 7a- (epoxymethano) -1H, 6aH-cyclopenta[c]furo[2, 3-b]furo[3', 2': 3, 4]cyclopenta[1, 2-d]furan-5, 9, 12 (4H) -trione; BN 52022. Grades: Highly Purified. CAS No. 15291-76-6. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
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