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3-[4- (Bromomethyl) phenyl]-3- (trifluoromethyl) diazirine is used as a reactant in the synthetic preparation of ginkgolide derivatives incorporating fluorescent and photoactivatable groups for photolabeling studies. Group: Biochemicals. Grades: Highly Purified. CAS No. 92367-11-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C9H6BrF3N2, Molecular Weight: 279.06. US Biological Life Sciences.
Worldwide
Ginkgolide A
Ginkgolide A (BN-52020) is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist. Uses: Scientific research. Group: Natural products. Alternative Names: BN-52020. CAS No. 15291-75-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0355.
Ginkgolide B
Ginkgolide B (BN-52021), an important active terpenoid from Ginkgo biloba leaves, is reported to increase cell viability and decrease cell apoptosis.IC50 value:Target:In vitro: Ginkgolide B (0.2 or 0.4 μg/ml) was added to the culture medium in vitro led to increases in cell viability and decreases in the number of hippocampal cells undergoing AAPH-induced apoptosis. Ginkgolide B caused a dose-related protection against dysrhythmias; the antiarrhythmic effect of ginkgolide B was comparable to that of diltiazem and superior to the activity of metoprolol. Ginkgolide B can presumably prevent the re-entry mechanism involved in the development of ischemia-induced rhythm disturbances.In vivo: Oral administration of ginkgolide B (2 mg/kg/day, p.o.) caused a significant increase in cell viability and a highly significant decrease in the numbers of both spontaneously occurring and AAPH-induced apoptoses. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Deoxyginkgolide C. Product Category: Inhibitors. Appearance: White powder. CAS No. 15291-77-7. Molecular formula: C20H24O10. Mole weight: 424.4. Purity: 0.98. IUPACName: (1R,3R,6R,7S,8S,10R,11R,12R,13S,16S,17R)-8-tert-butyl-6,12,17-trihydroxy-16-methyl-2,4,14,19-tetraoxahexacyclo[8.7.2.01,11.03,7.07,11.013,17]nonadecane-5,15,18-trione. Canonical SMILES: C[C@@H]1C(=O)O[C@@H]2[C@]1([C@@]34C(=O)O[C@H]5[C@]3([C@H]2O)[C@@]6([C@@H](C5)C(C)(C)
Ginkgolide B
Ginkgolide B (BN-52021), a terpene lactone, is a potent platelet activating factor antagonist. Ginkgolide B protects endothelial cells via the activation of PXR from injuries induced by xeno- and endobiotics. Ginkgolide B can pass through the brain-blood barrier. Ginkgolide B has anti-oxidant, anti-inflammatory, anti-tumor, and anti- apoptotic activity. Ginkgolide B has marked neuroprotective effects against ischemia-induced impairments [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: BN-52021. CAS No. 15291-77-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0784.
Ginkgolide J
Ginkgolide J. Group: Biochemicals. Grades: Highly Purified. CAS No. 107438-79-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H24O10. US Biological Life Sciences.
Worldwide
Ginkgolide J
Ginkgolide J is extracted from the seed of Ginkgo biloba L. It reduces apoptotic damage in cultured chick embryonic neurons. It contributes to the antioxidant properties of G. biloba. It has the superoxide scavenging effect and neuroprotective effect. Synonyms: 7beta-hydroxyginkgolide a; BN 52024; GinkgolideA, 7-hydroxy-, (7β)-; J Ginkgoli. Grades: >98%. CAS No. 107438-79-9. Molecular formula: C20H24O10.
levopimaradiene synthase
In Ginkgo, the enzyme catalyses the initial cyclization step in the biosynthesis of ginkgolides, a structurally unique family of diterpenoids that are highly specific platelet-activating-factor receptor antagonists. Levopimaradiene is widely distributed in higher plants. In some species the enzyme also forms abietadiene, palustradiene, and neoabietadiene. Group: Enzymes. Synonyms: PtTPS-LAS; LPS; copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]. Enzyme Commission Number: EC 4.2.3.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5190; levopimaradiene synthase; EC 4.2.3.32; PtTPS-LAS; LPS; copalyl-diphosphate diphosphate-lyase [abieta-8(14),12-diene-forming]. Cat No: EXWM-5190.
Ginkgolide A
Family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists. Group: Biochemicals. Alternative Names: (1R, 3S, 3aS, 4R, 6aR, 7aR, 7bR, 8S, 10aS, 11aS) -3- (1, 1-Dimethylethyl) hexahydro-4, 7b-dihydroxy-8-methyl-9H-1, 7a- (epoxymethano) -1H, 6aH-cyclopenta[c]furo[2, 3-b]furo[3', 2': 3, 4]cyclopenta[1, 2-d]furan-5, 9, 12 (4H) -trione; BN 52020. Grades: Highly Purified. CAS No. 15291-75-5. Pack Sizes: 100mg. US Biological Life Sciences.