Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Glibenclamide | Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel ( K ATP ) inhibitor and can be used for the research of diabetes and obesity [1]. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of K ATP and inhibits the cystic fibrosis transmembrane conductance regulator protein ( CFTR ) [3]. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability [4]. Glibenclamide can induce autophagy [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glyburide. CAS No. 10238-21-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15206. |  |
| Glibenclamide | Glibenclamide. Group: Biochemicals. Grades: Purified. CAS No. 10238-21-8. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| Glibenclamide (5-Chloro-N- [4- (cyclohexyl ureidosulfonyl ) phene thyl ] -2-methoxybenzamide , Glyburide, N-p-[2- (5-Chloro-2-methoxybenzamido) ethyl]benzenesulfonyl-N?-cyclohexylurea) | Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin secretion. Group: Biochemicals. Grades: Highly Purified. CAS No. 10238-21-8. Pack Sizes: 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Glibenclamide impurity 10 | Glibenclamide impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 151890-69-6. Molecular formula: C19H21ClN2O6S. Mole weight: 440.9. Catalog: APB151890696. |  |
| Glibenclamide Impurity B | Glibenclamide Impurity B is an impurity in the synthesis of Gyburide. Synonyms: Methyl {{4-{2- [ (5-chloro-2-methoxybenzoyl) amino] ethyl}phenyl}sulfonyl}carbamate; N-[[4-[2-[ (5-Chloro-2-methoxybenzoyl) amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester; [[4-[2-[ (5-Chloro-2-methoxybenzoyl) amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl. Grades: > 95%. CAS No. 21165-77-5. Molecular formula: C18H19ClN2O6S. Mole weight: 426.88. |  |
| Glibenclamide potassium salt | Glibenclamide potassium salt is a salt form of Glibenclamide, a KATP channel blocker used for the treatment of type 2 diabetes. Glibenclamide binds to and inhibits the sulfonylurea receptor 1 (SUR1), the regulatory subunit of the ATP-sensitive potassium channels (KATP) in pancreatic β cells. Uses: Antidiabetic. Synonyms: Glibenclamide potassium salt; Glyburide potassium salt; 23047-14-5; dipotassium; 5-chloro-N-[2-[4-[ (N-cyclohexyl-C-oxidocarbonimidoyl) sulfamoyl]phenyl]ethyl]-2-methoxybenzenecarboximidate; E99010; 5-chloro-N- (4- (N- (cyclohexylcarbamoyl) sulfamoyl) phenethyl) -2-methoxybenzamide potassium. Grades: 99%. CAS No. 23047-14-5. Molecular formula: C23H26ClK2N3O5S. Mole weight: 570.18. | |
| Glyburide. (5-Chloro-N- [2- [4- [ [ [ (cyclohexylamino) carbonyl] amino] sulfonyl] phenyl] ethyl] -2-methoxybenzamide, Adiab, Azuglucon, Bastiverit, Glibenclamide, Glidiabet, Glimidstada) | A second generation sulfonylurea with hypoglycemic activity. Group: Biochemicals. Alternative Names: 5-Chloro-N- [2- [4- [ [ [ (cyclohexylamino) carbonyl] amino] sulfonyl] phenyl] ethyl] -2-methoxybenzamide, Adiab, Azuglucon, Bastiverit, Glibenclamide, Glidiabet, Glimidstada. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Glyburide-d11 (5-Chloro-N- [2- [4- [ [ [ (cyclohexylamino) carbonyl] amino] sulfonyl] phenyl] ethyl] -2-methoxybenzamide-d11, Adiab-d11, Azuglucon-d11, Bastiverit-d11, Glibenclamide-d11, Glidiabet-d11, Glimidstada-d11 ) | A second generation sulfonylurea with hypoglycemic activity. Group: Biochemicals. Alternative Names: 5-Chloro-N- [2- [4- [ [ [ (cyclohexylamino) carbonyl] amino] sulfonyl] phenyl] ethyl] -2-methoxybenzamide-d11, Adiab-d11, Azuglucon-d11, Bastiverit-d11, Glibenclamide-d11, Glidiabet-d11, Glimidstada-d11. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Glyburide (Glibenclamide) | Pharmaceutical Secondary Standard; Certified Reference Material. Group: Pharmacopeia & metrological institutes standards. | |
| 5-Chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide | Glibenclamide Impurity A is an impurity arising in the synthesis of Glyburide. Synonyms: 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide. Grades: > 95 %. CAS No. 16673-34-0. Molecular formula: C16H17ClN2O4S. Mole weight: 368.84. | |
| 5-?chloro-?N-? [2-? [4-? [ [ [ [ (trans-?4-?hydroxycyclohexyl) ?amino] ?carbonyl] ?amino] ?sulfonyl] ?phenyl] ?ethyl] ?-?2-?methoxy-Benzamide | A metabolite of Glyburide which is used as an antidiabetic. Synonyms: 4-Hydroxyglibenclamide; rac trans-4-Hydroxy Glyburide; 23155-00-2; rac cis-4-Hydroxy Glyburide; 23155-04-6; 132054-81-0; trans-4-Hydroxyglyburide; 4-trans-Hydroxyglibenclamide; 4-trans-Hydroxy-glibenclamide; 4-Hydroxyglyburide, trans-; 4-trans-Hydroxycyclohexyl Glyburide; 8J8OD7PL2J; rac-trans-4-hydroxy Glyburide; 5-chloro-N-[2-[4-[ (4-hydroxycyclohexyl) carbamoylsulfamoyl]phenyl]ethyl]-2-methoxybenzamide; cis-5-Chloro-N-[2-[4-[[[[(4-hydroxycyclohexyl); aMino] carbonyl] aMino] sulfonyl] phenyl] ethyl] -2-MethoxybenzaMide; 5-Chloro-N- (4- (N- ( (4-hydroxycyclohexyl) carbamoyl) sulfamoyl) phenethyl) -2-methoxybenzamide. CAS No. 23155-00-2. Molecular formula: C23H28ClN3O6S. Mole weight: 510. | |
| 6-Dehydrocortisol | 6-Dehydrocortisol. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-Dehydrocortisol, Delta6-Hydrocortisone,1-[[4-[2-[(3,5-Di-chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]-3-cyclohexylurea, Glibenclamide Imp. E (Pharmeuropa), NSC 12881, 11beta,17,21-Trihydroxypregna-4,6-diene-3,20-dione, Hydrocortisone Imp. E (EP), Pregna-4,6-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)- (9CI), Delta6-Cortisol, Pregna-4,6-diene-3,20-dione, 11beta,17,21-trihydroxy- (8CI). CAS No. 600-99-7. Pack Sizes: 10MG. IUPAC Name: (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one. Molecular formula: C21H28O5. Mole weight: 360.44. Catalog: APS600997A. SMILES: C[C@]12CCC(=O)C=C1C=C[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)C[C@H](O)[C@H]23. Format: Neat. Shipping: Room Temperature. | |
| ER-Tracker Green | ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 730931-46-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1297. | |
| ER-Tracker Red | ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation. Ex/Em=587/615 nm[1]. Uses: Scientific research. Group: Fluorescent dye. Pack Sizes: 50 ?g; 100 ?g. Product ID: HY-D1431. | |
| Glyburide potassium salt | Glyburide is a sulfonylurea receptor 1 (SUR1) inhibitor linked to ATP-sensitive potassium channel Kir6.2 with an IC50 value of 4.3 nM. Synonyms: Glibenclamide; 5-chloro-N- [2- [4- [ [ [ (cyclohexylamino) carbonyl] amino] sulfonyl] phenyl] ethyl] -2-methoxy-benzamide, monopotassium salt. Grades: ≥98%. CAS No. 52169-36-5. Molecular formula: C23H28ClN3O5S·K. Mole weight: 533.1. | |
| N,N-Diethylaminoethyl 2,2-diphenylvalerate hydrochloride (SKF-525A HCl) | Cytochrome P-459 inhibitor; blocks glibenclamide-sensitive K+ channels; inhibits neuronal nitric oxide synthetase; stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. Group: Biochemicals. Alternative Names: α-Phenyl-α-Propylbenzeneacetic Acid 2-(Diethylamino)ethyl Ester Hydrochloride; 2,2-Diphenylvaleric Acid 2-(Diethylamino)ethyl Ester Hydrochloride; 2-(Diethylamino)ethyl 2,2-Diphenylvalerate Hydrochloride; Proadifen Hydrochloride; RP 5171; SKF 525; U 5446. Grades: Highly Purified. CAS No. 62-68-0. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??ClNO?, Molecular Weight: 389.96. US Biological Life Sciences. | Worldwide |
| Proadifen Hydrochloride | Proadifen hydrochloride is a Cytochrome P450 inhibitor (IC50 = 19μM) and stimulate endothelial cell prostacyclin production. Uses: Cytochrome p-459 inhibitor; blocks glibenclamide-sensitive k+ channels. Synonyms: 2-(diethylamino)ethyl 2,2-diphenylpentanoate;hydrochloride;SKF-525A, Hydrochloride; Proadifen hydrochloride; NSC 170997; NSC-170997; NSC170997. Grades: ≥98%. CAS No. 62-68-0. Molecular formula: C23H32ClNO2. Mole weight: 389.96. | |
| RS 79948 hydrochloride | RS 79948, a sulfur compound, is an α2-adrenoreceptor antagonist (Kd= 0.18, 0.19 and 0.42 nM for α2B α2C and α2A, respectively in rat). It increases insulin secretion and synergistically augments insulinotropic effect of glibenclamide. Synonyms: 6H-Isoquino[2,1-g][1,6]naphthyridine, 12-(ethylsulfonyl)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-, hydrochloride (1:1), (8aR,12aS,13aS)-; 6H-Isoquino[2,1-g][1,6]naphthyridine, 12-(ethylsulfonyl)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-, monohydrochloride, (8aR,12aS,13aS)-; 6H-Isoquino[2,1-g][1,6]naphthyridine, 12-(ethylsulfonyl)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-, monohydrochloride, [8aR-(8aα,12aα,13aα)]-; RS 79948-197; RS79948 hydrochloride; RS-79948 hydrochloride; (8aR,12aS,13aS)-5,8,8a,9,10,11,12,12a,13,13a-dechydro-3-methoxy-12-(ethylsulfonyl)-6H-isoquino[2,1-g][1,6]naphthyridine hydrochloride. Grades: ≥99% by HPLC. CAS No. 186002-54-0. Molecular formula: C19H28N2O3S.HCl. Mole weight: 400.96. | |
| SKF-525A, Hydrochloride - CAS 62-68-0 | Cell permeable. Blocks glibenclamide-sensitive K+ channels. Inhibits neuronal nitric oxide synthase. Also inhibits hepatic drug metabolism by inhibiting the cytochrome P450 system. Group: Fluorescence/luminescence spectroscopy. | |
| SKF-525A, Hydrochloride (Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl) | Cytochrome P-459 inhibitor; blocks glibenclamide-sensitive K+ channels; inhibits neuronal nitric oxide synthetase; stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. Group: Biochemicals. Alternative Names: Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
