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| Product | Description | |
|---|---|---|
| Globo H (hexassacharide) | Globo-H is a prominently employed bioactive glycolipid antigen, serving as a pivotal compound in the exploration of cancer and immunotherapy. It finds primary application in the research of vaccines and targeted approaches for drug dissemination. Synonyms: Fuc-a-1,2-Gal-b-1,3-GalNAc-b-1,3-Gal-a-1,4-Gal-b-1,4-Glc; alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GalpNAc-(1->3)-alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-beta-D-Glcp; alphaFuc(1-2)betaGal(1-3)betaGalNAc(1-3)alphaGal(1-4)betaGal(1-4)betaGlc. CAS No. 207384-96-1. Molecular formula: C38H65NO30. Mole weight: 1015.91. |  |
| Globo H pentenyl glycoside | Globo H pentenyl glycoside. CAS No. 284663-02-1. Molecular formula: C43H73NO30. Mole weight: 1084.03. | |
| Chaetoglobosin A | from Chaetomium globosum, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Globo-H-b-N-acetyl propargyl | Globo-H-b-N-acetyl propargyl is a groundbreaking biomedical compound, unveiling its prowess in the research of malignant neoplasms. Exerting its profound inhibitory effect, it precisely disarms the intricate molecular networks dictating the relentless proliferation and metastasis of cancerous cells. Synonyms: Fuc-a-1,2-Gal-b-1,3-GalNAc-b-1,3-Gal-a-1,4-Gal-b-1,4-Glc-b-NAc-Prop. Molecular formula: C43H70N2O30. Mole weight: 1095.01. | |
| Globo-H BSA conjugate | Globo-H BSA conjugate. | |
| Globohexaosylceramide | Globohexaosylceramide is an intricate carbohydrate-derived compound, finding its application as a research tool in unraveling mysteries pertaining to specific ailments such as cancer. Synonyms: Ceramide, 1-O-[O-6-deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-; Ganglioside GA3, O-6-deoxy-α-L-galactopyranosyl-(1→2)-O-β-D-galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4B)-; Globo H; Globo-H hexaose. Grade: 90%. CAS No. 77538-31-9. | |
| Globo-H hexasaccharide-sp-biotin | Globo-H Hexasaccharide-sp-biotin is a biomedical product used to aid in the treatment and detection of certain types of cancer, particularly breast and ovarian cancer. It acts as a therapeutic agent by targeting and delivering drugs to cancer cells while sparing healthy cells. Additionally, it serves as a diagnostic tool by enabling the visualization of cancer cells through a process known as immunoassay. Synonyms: Globo-H Hexaose-b-NAc-Spacer-biotin. Grade: 90%. Molecular formula: C61H102N8O35S. Mole weight: 1539.56. | |
| Globo-N-tetraose-APD-HSA | Globo-N-tetraose-APD-HSA. | |
| globoside α-N-acetylgalactosaminyltransferase | This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: uridine diphosphoacetylgalactosamine-globoside α-acetylgalactosaminyltransferase; Forssman synthase; globoside acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide α-N-acetyl-D-galactosaminyltransferase; UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-(1?3)-D-galactosyl-(1?4)-D-galactosyl-(1?4)-D-glucosyl-(1<->1)-ceramide α-N-ace. Enzyme Commission Number: EC 2.4.1.88. CAS No. 52037-97-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2628; globoside α-N-acetylgalactosaminyltransferase; EC 2.4.1.88; 52037-97-5; uridine diphosphoacetylgalactosamine-globoside α-acetylgalactosaminyltransferase; Forssman synthase; globoside acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide α-N-acetyl-D-galactosaminyltransferase; UDP-N-acetyl-D-galactosamine:N-acetyl-D-galactosaminyl-(1?3)-D-galactosyl-(1?4)-D-galactosyl-(1?4)-D-glucosyl-(1<->1)-ceramide α-N-acetyl-D-galactosaminyltransferase. Cat No: EXWM-2628. |  |
| Globosuxanthone A | Globosuxanthone A is a fungal metabolite isolated from C. globosum which is a well-known mesophilic member of the mold family Chaetomiaceae. Globosuxanthone A is cytotoxic to various human solid tumor cell lines, including MCF-7, PC3, LNCap and DU145 cells. Synonyms: (1R,2R)-2,9-dihydro-1,2,8-trihydroxy-9-oxo-1H-xanthene-1-carboxylic acid, methyl ester; rel-methyl (1R,2R)-1,2,8-trihydroxy-9-oxo-2,9-dihydro-1H-xanthene-1-carboxylate. Grade: ≥95%. CAS No. 917091-74-8. Molecular formula: C15H12O7. Mole weight: 304.25. | |
| Globotriaosylceramid?e Sphingosine-d2,13C tert-Butyldimethylsilyl | Globotriaosylceramid?e Sphingosine-d2,13C tert-Butyldimethylsilyl is a labeled Fabry disease biomarker. Synonyms: (2S,?3R,?4E)?-2-Amino-3-((tert-butyldimethylsilyl)oxy)-4-octadecenyl-d2,13C O-α-D-Galactopyranosyl-(1→4)?-O-β-D-galactopyranosyl-(1→4)?-β-D-glucopyranoside; lyso-Gb3-d2,13C tert-Butyldimethylsilyl; (2R,3R,4S,5R,6R)-2-(((2R,3R,4R,5R,6S)-6-(((2R,3S,4R,5R,6R)-6-(((2S,3R,E)-2-Amino-3-((tert-butyldimethylsilyl)oxy)octadec-4-en-1-yl-d2, 13C)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Molecular formula: C41[13C]H79D2NO17Si. Mole weight: 903.18. | |
| Globotriaosylsphingosine | Globotriaosylsphingosine (lyso-Gb3) inhibits the growth of fibroblasts, as well as their differentiation into myofibroblasts, and collagen expression. Globotriaosylsphingosine can be used for Fabry disease research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: lyso-Gb3. CAS No. 126550-86-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12408. |  |
| Globotriaosylsphingosine | Globotriaosylsphingosine, or Gb3, is a crucial biomarker used in the biomedical industry to diagnose and monitor the progression of Fabry disease. This rare genetic disorder results from the deficiency of a specific enzyme, leading to the abnormal accumulation of Gb3 within various organs. Precise and sensitive detection of Gb3 helps physicians determine the severity of Fabry disease and devise personalized treatment plans accordingly. Synonyms: a-D-Gal-(1→4)-b-D-Gal-(1→4)-b-D-Glc-1→O-sphingosine; Lysoglobotriaosylceramide; Ceramide trihexoside; lysoGb3; (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside; β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecenyl O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-; Globotriaosylceramide sphingosine; lyso-Gb3. Grade: >99%. CAS No. 126550-86-5. Molecular formula: C36H67NO17. Mole weight: 785.91. | |
| Globotriose 2-(2-carboxyethylthio)ethane | Globotriose 2-(2-carboxyethylthio)ethane is an extensively employed compound, serving as a cornerstone for research purposes in various ailments including hemolytic uremic syndrome and Escherichia coli-induced bacterial infections. Synonyms: 2-(2-Carboxyethylthio)-ethyl 4-O-[4-O(a-D-galactopyranosyl)-b-D-galactopyranosyl]-b-D-glucopyranoside. Molecular formula: C23H40O18S. Mole weight: 636.62. | |
| Globotriose-APE-HSA | Globotriose-APE-HSA. | |
| Globotriose-HSA | Globotriose-HSA. | |
| Globotriose-HSA (3 atom spacer) | Globotriose-HSA (3 atom spacer) is a potential therapeutic agent used in the treatment of shiga toxin-producing E. coli infections. It comprises a synthetic molecule made of three sugar molecules connected to human serum albumin with a three-atom spacer. The compound can bind to the shiga toxin produced by E. coli, preventing it from attaching to cell receptors and causing damage to vital organs. Synonyms: Globotriose-HSA conjugate, 3 Atom spacer; Gal(a1-4)Gal(b1-4)Glc-HSA (3 atom spacer); alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc-HSA (3 atom spacer); O-α-D-Galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucose-HSA (3 atom spacer). | |
| 2,5-Dideoxy-2,5-imino-D-mannitol HCl | 2,5-Dideoxy-2,5-imino-D-mannitol HCl, a highly efficacious pharmaceutical compound, occupies a prominent position in the biomedical landscape owing to its profound therapeutic value in tackling Fabry disease. This exceptionally intricate and infrequent genetic anomaly manifests itself as an aberrant accumulation of globotriaosylceramide (GL-3). The remarkable inhibitory action of this medication on the alpha-galactosidase A enzyme effectively restricts the accrual of GL-3, thereby thwarting the relentless advancement of this incapacitating ailment. Synonyms: 2,5-Anhydro-2,5-imino-D-mannitol HCl. CAS No. 210115-92-7. Molecular formula: C6H14ClNO4. Mole weight: 199.63. | |
| α-1,4-Galactosyltransferase from Neisseria meningitides, Recombinant | Lactosylceramide 4-alpha-galactosyltransferase is an enzyme that in humans is encoded by the A4GALT gene. The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Group: Enzymes. Synonyms: lactosylceramide 4-alpha-galactosyltransferase; Galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase; globotriaosylceramide/CD77 synthase; histo-blood group Pk UDP-ga. Enzyme Commission Number: EC 2.4.1.228. CAS No. 52725-57-2. Purity: min 95% by SDS-PAGE. Galactosyltransferase. Mole weight: 34 kDa. Source: E. coli. Species: Neisseria meningitides. lactosylceramide 4-alpha-galactosyltransferase; Galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase; globotriaosylceramide/CD77 synthase; histo-blood group Pk UDP-galactose; UDP-galactose:lactosylceramide 4II-alpha-D-galactosyltransferase; UDP-galactose:beta-D-galactosyl-(1->4)-D-glucosyl(1<->1)ceramide 4II-alpha-D-galactosyltransferase; UDP-galactose:beta-D-galactosyl-(1->4)-D-glucosyl-(1<->1)-ceramide 4II-alpha-D-galactosyltransferase; α-1,4-Galactosyltransferase. Cat No: NATE-1479. | |
| Blood group H type 1 trisaccharide-biotin | Blood group H type 1 trisaccharide-biotin is a biologically significant sugar molecule fused with biotin, serving as a vital probe in numerous biomedicine researches, including but not limited to exploring blood types locomotion with pathological microorganisms and developing diagnostic as well as therapeutic procedures for ailments integral to blood constitution. This bioactive substance traverses database of biochemicals and is procurable from chemical suppliers to ensure optimal laboratory proficiency. Synonyms: alpha-L-Fucp-(1->2)-beta-D-Galp-(1->3)-beta-D-GlcpNAc-biotin; Globo-H-biotin; H type I-biotin; H type I epitope-biotin; H type I trisaccharide-biotin; α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc-biotin; αLFuc(1-2)βDGal(1-3)βDGlcNAc-biotin; Biotinyl Blood Group H Type 1 Trisaccharide; Fucα(1-2)Galβ(1-3)GlcNAc-β-O-(CH2)8-S-(CH2)2-NH-biotin; Blood Group H type I trisaccharide, spacer-biotin conjugate. Molecular formula: C33H56N4O17S. Mole weight: 812.88. | |
| C2 Adamantanyl Galactosylceramide (d18:1/2:0) | C2 Adamantanyl Galactosylceramide (d18:1/2:0) is a bioactive sphingolipid. It reduces globotriaosylceramide 3 synthesis from exogenous lactosylceramide in microsomes. AdaGalCer stimulates recombinant glucocerebrosidase activity in a pH-dependent manner. It activates glucocerebrosidase to decrease glucosylceramide accumulation in fibroblasts and lymphoblasts isolated from patients with Gaucher and Fabry disease, respectively. Synonyms: [(2S,3R,4E)-2-[(1-Adamantyl)acetylamino]-3-hydroxy-4-octadecenyl]beta-D-galactopyranoside; N-(1-Adamantaneacetyl)-galactosylceramide; Adamantanyl Galactosyl(β) Ceramide; AdaGalCer(d18:1/2:0). Grade: ≥98%. CAS No. 574738-16-2. Molecular formula: C36H63NO8. Mole weight: 637.89. | |
| Chaetoviridin A | Chaetoviridin A is a fungal metabolite isolated from Chaetomium globosum, which exhibits antifungal activity against plant pathogenic fungi. Grade: >95% by HPLC. CAS No. 128252-98-2. Molecular formula: C23H25ClO6. Mole weight: 432.9. | |
| Dynemicin A | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. Dynemicin A has a strong killing effect on a variety of tumor cells at Pg/mL level. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1S,4R,4aR,14S,14aS)-1,4,4a,7,12,13,14,14a-Octahydro-6,8,11-trihydroxy-3-methoxy-1-methyl-7,12-dioxo-4a,14a-epoxy-4,14-(3-hexene-1,5-diyne-1,6-diyl)naphtho[2,3-c]phenanthridine-2-carboxylicacid; Dynemicin; BU 3420T. Grade: 95%. CAS No. 124412-57-3. Molecular formula: C30H19NO9. Mole weight: 537.47. | |
| Dynemicin L | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylic acid, 8-chloro-5,8,9,14,15,16-hexahydro-1,4,6,17-tetrahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9R,14S,17S,18S)-(9CI). CAS No. 127032-74-0. Molecular formula: C30H22NO9Cl. Mole weight: 575.95. | |
| Dynemicin M | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: (1R)-3,4,4a,13,14,14a-Hexahydro-4a,6,8,11,14a-pentahydroxy-3β-methoxy-1β-methyl-4,14-[1,2]benzenonaphtho[2,3-c]phenanthridine-2,7,12(1H)-trione. Grade: ≥98%. CAS No. 127003-54-7. Molecular formula: C29H23NO9. Mole weight: 529.49. | |
| Dynemicin N | It is produced by the strain of Micromonospora chersina sp. M 956-I and M. globosa. The cyclic enediyne part of enediyne antibiotics is cycled by Bergman to form aromatic diradicals, which quickly seize hydrogen atoms from the DNA skeleton and break the DNA strand, thus killing tumor cells. Synonyms: 9,8,14-[1]Buten[1]yl[4]ylideneanthra[1,2-b]benz[f]azocine-19-carboxylicacid,5,8,9,14,15,16-hexahydro-1,4,6,8,17-pentahydroxy-20-methoxy-18-methyl-5,16-dioxo-, (8R,9S,14S,17S,18S)-(9CI). CAS No. 127003-55-8. Molecular formula: C30H23NO10. Mole weight: 557.50. | |
| Fosthiazate | Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp. , Globodera spp. , and Pratylenchus spp. , through inhibiting the synthesis of acetylcholinesterase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 98886-44-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W020785. | |
| GA2-Ganglioside | GA2-Ganglioside, a glycolipid situated on the cell surface, performs a crucial action by boosting communication between neighboring nerve cells in the nervous system. Its medicinal potency in treating diverse neurological illnesses, including Parkinson's and Alzheimer's, has been researched extensively. Furthermore, it seems GA2-Ganglioside promotes the functionality and longevity of dopaminergic neurons, making it a highly sought-after therapy for Parkinson's. Synonyms: Asialoganglioside-GM2; Gangliotriosyl ceramide; GgOse3Cer; b-GalNAc-(1→4)-b-Gal-(1→4)-b-Glc-(1→1)-Cer; Ceramide, 1-O-[O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-; 1-O-[O-2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-ceramide; Asialo Gm2; Asialoganglioside GM2; Cg3Cer; Ganglio-N-triaosylceramide; Ganglioside A2; Ganglioside GA2; Ganglioside Gg3; Gangliotriaosylceramide; Gangliotriosylceramide; Gg3Cer; Glycolipid GA2; Glycosphingolipid GA2; Tay-Sachs globoside. CAS No. 35960-33-9. Molecular formula: C56H104N2O18. Mole weight: 1093.43. | |
| Gliocladic acid | It is produced by the strain of Gliocladium virens SANK 12679, Chaetomium globosum SANK 13379, Trichoderma viride SANK 13479. It has anti-tumor activity. Synonyms: (E)-2-Hydroxymethyl-3-[3-(hydroxymethyl)-6alpha-(1-methylethyl)-2-cyclohexen-1beta-yl]propenoic acid. CAS No. 82425-48-7. Molecular formula: C14H22O4. Mole weight: 254.32. | |
| Globoisotetraose | Globoisotetraose is an extensively utilized synthetic compound, showcasing considerable potential in the precise targeting of tumor-associated carbohydrate antigens, with specific emphasis on the Globo H antigen, for the research of cancer. Synonyms: Isoglobotetraose; O-2-(Acetylamino)-2-deoxy-b-D-galactopyranosyl-(1→3)-O-a-D-galactopyranosyl-(1→3)-O-b-D-galactopyranosyl-(1→4)-D-glucose. CAS No. 75645-26-0. Molecular formula: C26H45NO21. Mole weight: 707.63. | |
| Globomycin | Globomycin is a lipopeptide antibiotic and signal peptidase II (LspA) inhibitor from Streptomyces hagronensis that inhibits the growth of enteric Gram-negative bacteria by inhibiting cell wall synthesis. It inhibits the processing of prolipoprotein by irreversibly binding to peptidase. Uses: Protease inhibitors. Synonyms: Antibiotic SF-1902A1; Cyclo[Gly-[(2R,3R)-3-hydroxy-2-methyl-1-oxononyl]-N-methyl-L-Leu-L-aIle-L-Ser-L-aThr-]; SF-1902A1; Glycine, N-(N-(N-(N-(N-(3-hydroxy-2-methyl-1-oxononyl)-N-methylleucyl)-L-alloisoleucyl)-L-seryl)-L-allothreonyl)-, rho-lactone; SF 1902. Grade: ≥95%. CAS No. 67076-74-8. Molecular formula: C32H57N5O9. Mole weight: 655.82. | |
| Globo-N-tetraose | Globo-N-tetraose is a potential compound exhibiting promising properties in the research of cancer, specifically in targeting cancer cells expressing the Globo H antigen. By blocking the interaction between Globo H and corresponding antibodies, Globo-N-tetraose shows potential as an antitumor compound. Synonyms: GalNAc-b-1,3-Gal-a-1,4-Gal-b-1,4-Glc; O-2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucose; Globotetraose; N-((2S,3R,4R,5R,6R)-2-(((2R,3R,4S,5S,6R)-2-(((2R,3R,4R,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-(((2R,3R,4R,5R)-1,2,4,5-tetrahydroxy-6-oxohexan-3-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide. CAS No. 75660-79-6. Molecular formula: C26H45NO21. Mole weight: 707.63. | |
| Globoside | Globoside is a glycosphingolipid abundantly present in human erythrocytes and diverse tissues, exhibiting multifaceted roles as a microbial toxin receptor and a regulator of cell adhesion and signal transduction. Synonyms: Globotetraosylceramide; Cytolipins; GlcNAc (b1-3)Gal (a1-4) Gal (b1-4) Glc b1-1 Cer; 1-O-[O-2-(Acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→3)-O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranosyl]-ceramide; Cytolipin K; CQH; CQH (globoside); Ganglioside Gb4; Ganglioside GL 4; Gb4; Gb4Cer; Globo-N-tetraosylceramide; Globoside (human erythrocytes); Globoside Gb 4; Globoside GL 4; Globoside I; Globosidic acid; Globotetraosylceramide; Parvovirus B19 receptor; Tetrahexosylceramide. CAS No. 11034-93-8. | |
| globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase | Globoside is a neutral glycosphingolipid in human erythrocytes and has blood-group-P-antigen activity. The enzyme requires a divalent cation for activity, with Mn2+ required for maximal activity. UDP-GalNAc is the only sugar donor that is used efficiently by the enzyme: UDP-Gal and UDP-GlcNAc result in very low enzyme activity. Lactosylceramide, globoside and gangliosides GM3 and GD3 are not substrates. For explanation of the superscripted '3' in the systematic name, see GL-5.3.4. Group: Enzymes. Synonyms: uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase; globoside synthetase; UDP-N-acetylgalactosamine: globotriaosylceramide β-3-N-acetylgalactosaminyltransferase; galactosylgalactosylglucosylceramide β-D-acetylgalactosaminyltransferase; UDP-N-acetylgalactosamine: globotriaosylceramide β1,3-N-acetylgalactosaminyltrans. Enzyme Commission Number: EC 2.4.1.79. CAS No. 62213-46-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2619; globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase; EC 2.4.1.79; 62213-46-1; uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase; globoside synthetase; UDP-N-acetylgala | |
| Heptelidic acid | It is produced by the strain of Gliocladium virens, Chaetomium globosum, Trichoderma viride. It is a sesquiterpenoid antibiotic. It has antibacterial activity against anaerobes, especially has strong effect on fragile bacilli (MIC is 0.4 μg/mL). It has anti-plasmodium (IC80 is 0.01 μg/mL) and antitumor activity. It is also an inhibitor of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) that acts by binding to the cysteine-149 residue. Synonyms: Koningic acid; (+)-Heptelidic Acid; (5aS,6R,9S,9aS)-6-isopropyl-1-oxo-1,5a,6,7,8,9a-hexahydro-3H-spiro[benzo[c]oxepine-9,2'-oxirane]-4-carboxylic acid; Spiro[2-benzoxepin-9(3H),2'-oxirane]-4-carboxylicacid,1,5a,6,7,8,9a-hexahydro-6-(1-methylethyl)-1-oxo-, (2'S,5aS,6R,9aS)-; Avocettin. Grade: ≥95%. CAS No. 57710-57-3. Molecular formula: C15H20O5. Mole weight: 280.32. | |
| lactosylceramide 4-α-galactosyltransferase | For explanation of superscript II in systematic name, see 2-carb.37. Group: Enzymes. Synonyms: Galβ1-4Glcβ1-Cer α1,4-galactosyltransferase; globotriaosylceramide/CD77 synthase; histo-blood group Pk UDP-galactose; UDP-galactose:lactosylceramide 4II-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-(1?4)-D-glucosyl(1<->1)ceramide 4II-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-(1?4)-D-glucosyl-(1<->1)-ceramide 4II-α-D-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.228. CAS No. 52725-57-2. Galactosyltransferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2457; lactosylceramide 4-α-galactosyltransferase; EC 2.4.1.228; 52725-57-2; Galβ1-4Glcβ1-Cer α1,4-galactosyltransferase; globotriaosylceramide/CD77 synthase; histo-blood group Pk UDP-galactose; UDP-galactose:lactosylceramide 4II-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-(1?4)-D-glucosyl(1<->1)ceramide 4II-α-D-galactosyltransferase; UDP-galactose:β-D-galactosyl-(1?4)-D-glucosyl-(1<->1)-ceramide 4II-α-D-galactosyltransferase. Cat No: EXWM-2457. | |
| Lactosyl Ceramide, Bovine | Lactosyl Ceramide neutral glycosphingolipid (GSL) that is the common precursor of the ganglio-, globo-, globoiso-, lacto-, neolacto-, and muco-series of GSL. Promotes a time- and concentration-dependent proliferation of aortic smooth muscle cells via specific activation of ERK 1 (p44 MAP kinase). Also stimulates Ras-GTP loading, MEK and Raf kinases, p44 MAP kinase, and c-fos expression in human aortic smooth muscle cells. Applications: An inducer of ras-gtp loading, mek and raf kinases, p44 map kinase, c-fos expression. Group: Coenzymes. Synonyms: Ceramide β-lactoside. CAS No. 4682-48-8. Purity: ≥98%. Mole weight: 960.4. Form: Solid. Ceramide β-lactoside; Lactosyl Ceramide, Bovine; 4682-48-8. Cat No: COEC-107. | |
| Native Bovine Glutathione Peroxidase | Glutathione peroxidase is an enzyme which reduced lipid hydroperoxides into their corresponding alcohols. It also reduces free hydrogen peroxide in to water. In vivo it is responsible for protecting hemoglobin from oxidative breakdown. Applications: Glutathione peroxidase from bovine erythr ocytes was used as a positive control in cloning and characterization of full-length cdnas encoding two glutathione peroxidases (gpxs) from globodera rost ochiensis. it was used for the determination of glutathione peroxidase activity in human milk. Group: Enzymes. Synonyms: EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Enzyme Commission Number: EC 1.11.1.9. CAS No. 9013-66-5. Mole weight: mol wt 84.5 kDa. Activity: > 300 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing 25% sucrose and 2.5% dithiothreitol with sodium phosphate buffer salts. Source: Bovine erythr ocytes. Species: Bovine. EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Cat No: NATE-0322. | |
| Psychosine | Psychosine (Galactosylsphingosine), a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease [1]. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell types including, most relevantly to globoid cell leukodystrophy (GLD), oligodendrocytes. Psychosine causes cell death at least in part via apoptosis. Psychosine also is an inhibitor of PKC [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Galactosylsphingosine. CAS No. 2238-90-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-136490. | |
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