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| Product | Description | |
|---|---|---|
| Glucuronidase 67A from Bacteroides ovatus, Recombinant | In enzymology, an alpha-glucuronidase (EC 3.2.1.139) is an enzyme that catalyzes the chemical reaction: an alpha-D-glucuronoside + H2O <-> an alcohol + D-glucuronate. Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate. This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha-D-glucosiduronate glucuronohydrolase. This enzyme is also called alpha-glucosiduronase. Group: Enzymes. Synonyms: EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase. Enzyme Commission Number: EC 3.2.1.139. CAS No. 37259-81-7. Purity: >90% by SDS-PAGE. α-Glucuronidase. Mole weight: 81 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacteroides ovatus. EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase; Glucuronidase 67A. Cat No: NATE-1451. |  |
| α-glucuronidase | Considerable differences in the specificities of the enzymes from different fungi for α-D-glucosiduronates have been reported. Activity is also found in the snail. Group: Enzymes. Synonyms: α-glucosiduronase. Enzyme Commission Number: EC 3.2.1.139. CAS No. 37259-81-7. α-Glucuronidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3821; α-glucuronidase; EC 3.2.1.139; 37259-81-7; α-glucosiduronase. Cat No: EXWM-3821. | |
| α-Glucuronidase 4A from Thermotoga maritima, Recombinant | In enzymology, an alpha-glucuronidase (EC 3.2.1.139) is an enzyme that catalyzes the chemical reaction: an alpha-D-glucuronoside + H2O <-> an alcohol + D-glucuronate. Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate. This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha-D-glucosiduronate glucuronohydrolase. This enzyme is also called alpha-glucosiduronase. Group: Enzymes. Synonyms: EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase. Enzyme Commission Number: EC 3.2.1.139. CAS No. 37259-81-7. Purity: >50% by SDS-PAGE. α-Glucuronidase. Mole weight: 56.7 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Thermotoga maritima. EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase; α-Glucuronidase 4A. Cat No: NATE-1450. | |
| α-Glucuronidase from Cellvibrio japonicus, Recombinant | In enzymology, an alpha-glucuronidase (EC 3.2.1.139) is an enzyme that catalyzes the chemical reaction: an alpha-D-glucuronoside + H2O <-> an alcohol + D-glucuronate. Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate. This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha-D-glucosiduronate glucuronohydrolase. This enzyme is also called alpha-glucosiduronase. Group: Enzymes. Synonyms: EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase. Enzyme Commission Number: EC 3.2.1.139. CAS No. 37259-81-7. Purity: > 95 % as judged by SDS-PAGE. α-Glucuronidase. Mole weight: 97904.6 Da. Activity: 27.72 U/mg. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Cellvibrio japonicus NCIMB 10462. EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase. Cat No: NATE-1178. | |
| α-Glucuronidase from Opitutus terrae PB90-1, Recombinant | In enzymology, an alpha-glucuronidase (EC 3.2.1.139) is an enzyme that catalyzes the chemical reaction: an alpha-D-glucuronoside + H2O <-> an alcohol + D-glucuronate. Thus, the two substrates of this enzyme are alpha-D-glucuronoside and H2O, whereas its two products are alcohol and D-glucuronate. This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha-D-glucosiduronate glucuronohydrolase. This enzyme is also called alpha-glucosiduronase. Group: Enzymes. Synonyms: EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase. Enzyme Commission Number: EC 3.2.1.139. CAS No. 37259-81-7. Purity: > 95 % as judged by SDS-PAGE. α-Glucuronidase. Mole weight: 82809.8 Da. Activity: 21.12 U/mg. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Opitutus terrae PB90-1. EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase. Cat No: NATE-1179. | |
| α-Methyl-glucuronidase 115A from Bacteroides ovatus, Recombinant | α-Methyl-glucuronidase 115A from Bacteroides ovatus, Recombinant. Group: Enzymes. Synonyms: EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase. Enzyme Commission Number: EC 3.2.1.-. Purity: >90% by SDS-PAGE. α-Glucuronidase. Mole weight: 96.6 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacteroides ovatus. EC 3.2.1.139; alpha-D-glucosiduronate glucuronohydrolase; alpha-glucosiduronase; α-Methyl-glucuronidase 115A. Cat No: NATE-1452. | |
| Anti-?-Glucuronidase (C-Terminal) antibody produced in rabbit | ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Anti-?-Glucuronidase (N-Terminal) antibody produced in rabbit | ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| baicalin-β-D-glucuronidase | The enzyme also hydrolyses wogonin 7-O-β-D-glucuronide and oroxylin 7-O-β-D-glucuronide with lower efficiency. Neglegible activity with p-nitrophenyl-β-D-glucuronide. Group: Enzymes. Synonyms: baicalinase. Enzyme Commission Number: EC 3.2.1.167. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3849; baicalin-β-D-glucuronidase; EC 3.2.1.167; baicalinase. Cat No: EXWM-3849. | |
| β-D-Glucuronidase from Bacteria, Recombinant | β-glucuronidase catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption. Group: Enzymes. Synonyms: β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Enzyme Commission Number: EC 3.2.1.31. CAS No. 9001-45-0. GUSB. Mole weight: 68 kD (SDS-PAGE). Activity: > 170 U/mg protein. Storage: Below -20°C. Form: Glycerol Solution. Source: E. coli. Species: Bacteria. β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Cat No: NATE-1036. | |
| β-glucuronidase | This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. Group: Enzymes. Synonyms: β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase. Enzyme Commission Number: EC 3.2.1.31. CAS No. 9001-45-0. GUSB. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3894; β-glucuronidase; EC 3.2.1.31; 9001-45-0; β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase. Cat No: EXWM-3894. | |
| β-Glucuronidase | β-Glucuronidase. Group: Biochemicals. Alternative Names: 4-O-Methylglucuronidase; β-D-glucuronidase Acid; E.C. 3.2.1.31; Exo- β-D-glucuronidase; GUS; Glucuronidase; Ketodase; β-D-Glucuronidase; β-Glucuronide Glucuronohydrolase. Grades: Purified. CAS No. 9001-45-0. Pack Sizes: 10KU. US Biological Life Sciences. |  Worldwide |
| Beta-glucuronidase (bovine liver) | Beta-glucuronidase is an important lysosomal enzyme involved in the degradation of glucuronate-containing glycosaminoglycan [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9001-45-0. Pack Sizes: 100 KU. Product ID: HY-P2803A. |  |
| Beta-glucuronidase (Escherichia coli) | Beta-glucuronidase is an important lysosomal enzyme involved in the degradation of glucuronate-containing glycosaminoglycan [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9001-45-0. Pack Sizes: 25 KU; 50 KU; 100 KU. Product ID: HY-P2803. | |
| b-Glucuronidase Inhibitor (1-((6,8-Dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-3-(4-ethoxyphenyl)-1-(2-hydroxyethyl)thiourea) | An orally bioavailable trisubstituted thiourea compound that acts as a potent, uncompetitive and reversible inhibitor of bacterial b-glucuronidase activity (IC50 = 283nM; kcat/Km=0.0987s-1uM-1; Ki4nM in vitro assays against E. coli b-glucuronidase; EC50.7nM in b-glucuronidase expressing HB101 cells) with excellent selectivity over mammalian b-glucuronidases. Shown to directly target the 17-residue (360-376) loop structure that protects the active site of E. coli b-glucuronidase and alter its conformation. Displays negligible cytotoxicity toward both bacterial and mammalian epithelial cells (>100uM for HCT116, Caco-2 and CMT93 colon cancer cells) and offers protection against CPT-11 (50mg/kg, i.p., s.i.d. for 9 days)-induced toxicity in mice (10ug, p.o., b.i.d). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Fast ?-Glucuronidase, Recombinant | from limpets (Patella Vulgata), aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| glucuronosyl-disulfoglucosamine glucuronidase | This enzyme belongs to the family of hydrolases, to be specific those glycosidases that hydrolyse O- and S-glycosyl compounds. Group: Enzymes. Synonyms: glycuronidase; 3-D-glucuronsyl-2-N,6-disulfo-β-D-glucosamine glucuronohydrolase. Enzyme Commission Number: EC 3.2.1.56. CAS No. 37288-42-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3919; glucuronosyl-disulfoglucosamine glucuronidase; EC 3.2.1.56; 37288-42-9; glycuronidase; 3-D-glucuronsyl-2-N,6-disulfo-β-D-glucosamine glucuronohydrolase. Cat No: EXWM-3919. | |
| Native Abalone β-Glucuronidase | β-glucuronidase catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption. Group: Enzymes. Synonyms: β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Enzyme Commission Number: EC 3.1.2.31. CAS No. 9001-45-0. GUSB. Activity: 1,500,000-3,000,000 units/g solid or > 100,000 units/mL. Form: lyophilized powder, Supplied as a lyophilized powder containing citric acid or aqueous solution, Supplied as an aqueous solution containing 0.85% NaCl and 0.02% sodium azide. Source: Abalone. β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Cat No: NATE-0328. | |
| Native Bovine β-Glucuronidase | β-glucuronidase catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption. Applications: Β-glucuronidase is used as a reporter gene in gus assays to monitor gene expression. Group: Enzymes. Synonyms: β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Enzyme Commission Number: EC 3.2.1.31. CAS No. 9001-45-0. GUSB. Activity: Type B-10, ~10,000 units/mg solid; Type B-1, > 1,000,000 units/g solid; Type B-3, > 2,000,000 units/g solid. Source: Bovine liver. Species: Bovine. β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Cat No: NATE-0329. | |
| Native Escherichia coli β-Glucuronidase | β-glucuronidase catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption. Type ix-a, 1,000-5,000 units/mg protein; type vii-a, lyophilized powder, 5,000-20,000 units/mg protein. Applications: Β-glucuronidase is used as a reporter gene in gus assays to monitor gene expression. Group: Enzymes. Synonyms: β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Enzyme Commission Number: EC 3.2.1.31. CAS No. 9001-45-0. GUSB. Form: lyophilized powder. Source: Escherichia coli. β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Cat No: NATE-0330. | |
| Native Helix pomatia β-Glucuronidase | β-glucuronidase catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption. Type h-1, partially purified powder, > 300 kda units/g solid; type h-5, lyophilized powder, > 400 kda units/g solid; type h-3, aqueous solution, > 90 kda units/ml; type h-3af, aqueous solution, > 60 kda units/ml; type h-2, aqueous solution, > 85 kda units/ml; type hp-2, aqueous solution, > 100 kda units/ml. Applications: Clinical testing diagnostic assay manufacturing. Group: Enzymes. Synonyms: β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Enzyme Commission Number: EC 3.2.1.31. CAS No. 9001-45-0. GUSB. Storage: Store at -20°C. Form: partially purified powder or Aqueous solution in ~1.0 M ammonium sulfate with 3 mM sodium azide as preservative. Source: Helix pomatia. β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Cat No: NATE-0331. | |
| Native Limpets (Patella vulgata) β-Glucuronidase | β-glucuronidase catalyzes the breakdown of complex carbohydrates. In humans it converts conjugated bilirubin into the unconjugated form, making bilirubin suitable for reabsorption. Type l-ii, lyophilized powder, 1 kda kda-3 kda kda units/g solid; aqueous solution, > 85 kda units/ml. Group: Enzymes. Synonyms: β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Enzyme Commission Number: EC 3.2.1.31. CAS No. 9001-45-0. GUSB. Form: lyophilized powder or aqueous solution (Aqueous solution in 0.9% NaCl with 0.02% sodium azide as preservative). Source: Limpets (Patella vulgata). β-glucuronide glucuronohydrolase glucuronidase; exo-β-D-glucuronidase; ketodase; EC 3.2.1.31; 9001-45-0; β-D-glucuronoside glucuronosohydrolase; GUSB. Cat No: NATE-0332. | |
| 1-Naphthyl b-D-glucuronide | 1-Naphthyl b-D-glucuronide is a substrate used in biomedical research, particularly for detecting β-glucuronidase activity in bacteria. It aids in differentiating pathogenic E.coli strains, studying drug metabolism and glucuronidation processes in pharmacokinetics. Synonyms: 1-Naphthalenyl β-D-glucopyranosiduronic acid; Glucopyranosiduronic acid, 1-naphthyl, β-D-; 1-Naphthol glucuronide; 1-Naphthol β-D-glucuronide; 1-Naphthyl glucosiduronic acid; 1-Naphthyl glucuronide; 1-Naphthyl β-D-glucosiduronic acid; α-Naphthol glucuronide; α-Naphthyl β-D-glucuronide; α-Naphthyl β-glucuronide. CAS No. 17238-47-0. Molecular formula: C16H16O7. Mole weight: 320.29. |  |
| 2-Chloro-4-nitrophenyl 2,3,4,6-tetra-O-acetyl-b-D-glucopyranoside | 2-Chloro-4-nitrophenyl 2,3,4,6-tetra-O-acetyl-b-D-glucopyranoside, an extensively utilized biomedical agent in research, exhibits remarkable properties. Serving as a versatile substrate in the examination of vital enzymes, including glucuronidases, glycosidases, and beta-glucosidases, it is an indispensable tool. Moreover, its application facilitates comprehensive investigations into drug metabolism, enzyme activity, and the realm of drug discovery. Synonyms: β-D-Glucopyranoside, 2-chloro-4-nitrophenyl, 2,3,4,6-tetraacetate; 2-Chloro-4-nitrophenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside; (2-Chloro-4-nitrophenyl)-2,3,4,6-tetra-O-acetyl-beta-D-glucopyranoside; (2R,3R,4S,5R,6S)-2-(Acetoxymethyl)-6-(2-chloro-4-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 35023-71-3. Molecular formula: C20H22ClNO12. Mole weight: 503.84. | |
| 2'-Hydroxydaidzein | 2'-Hydroxydaidzein is a natural flavonoid found in the herbs of Crotalaria pallida. It shows significant concentration-dependent inhibitory effects on the release of beta-glucuronidase and lysozyme from rat neutrophils. Uses: Phytoalexin. Synonyms: 7,2',4'-Trihydroxyisoflavone; 3-(2,4-Dihydroxyphenyl)-7-hydroxy-4H-chroMen- 4-one. Grade: >97%. CAS No. 7678-85-5. Molecular formula: C15H10O5. Mole weight: 270.24. | |
| 2-Nitrophenyl b-D-glucuronide | 2-Nitrophenyl b-D-glucuronide is a small molecule used in the biomedical industry for detecting the activity of β-glucuronidase is an enzyme associated with various diseases. Its structure enables it to be easily cleaved by the enzyme, leading to the release of a yellow chromophore. This colorimetric change allows researchers to monitor and measure β-glucuronidase activity, providing valuable insights into drug metabolism and certain disease states. Synonyms: ONP-GlcA; 2-Nitrophenyl β-D-glucopyranosiduronic acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(2-nitrophenoxy)tetrahydro-2H-pyran-2-carboxylic acid; 2-Nitrophenyl β-D-Glucuronide. CAS No. 137629-36-8. Molecular formula: C12H13NO9. Mole weight: 315.23. | |
| (2S,3R,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic Acid | (2S,3R,4R,5S)-3,4,5-Trihydroxy-2-piperidinecarboxylic Acid and its derivatives were reported to have inhibitory activities against various glycosidases. It is also used in the synthesis of uronic-noeurostegine, which is a potential bacterial β-glucuronidase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 96861-04-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C6H11NO5, Molecular Weight: 177.16. US Biological Life Sciences. | Worldwide |
| 3-Carboxyumbelliferyl b-D-glucuronide dipotassium salt | 3-Carboxyumbelliferyl b-D-glucuronide dipotassium salt is a biochemical compound commonly used in the biomedical industry. This product is utilized for studying glucuronidase activity and drug metabolism. It serves as a substrate in enzymatic assays to measure the hydrolysis of glucuronide conjugates. Synonyms: β-D-Glucopyranosiduronic acid, 3-carboxy-2-oxo-2H-1-benzopyran-7-yl, dipotassium salt; 3-Carboxy-2-oxo-2H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid dipotassium salt. CAS No. 216672-17-2. Molecular formula: C16H12K2O11. Mole weight: 458.46. | |
| 3-Chlorogentisyl alcohol | 3-Chlorogentisyl alcohol is a potent E. coli β-glucuronidase inhibitor with an IC 50 value of 0.74 μM, an K i value of 0.58 μM. 3-Chlorogentisyl alcohol shows antiproliferative activity. 3-Chlorogentisyl alcohol has the potential for the research of anti-cancer and anti-inflammatory therapies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 32744-80-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151168. | |
| 3-Indolyl b-D-glucuronide | 3-Indolyl b-D-glucuronide is a crucial reagent used in biomedical research. It serves as a substrate for β-glucuronidase, allowing the detection and quantification of glucuronidase activity in various tissues and biological samples. This compound facilitates the study of drug metabolism, as well as the diagnosis and monitoring of certain diseases, including liver disorders and cancers. Synonyms: Indoxyl b-D-glucuronide; IBDG; 1H-Indol-3-yl β-D-glucopyranosiduronic acid; 3-Indolyl-β-D-glucuronide; Indol-3-yl β-D-glucosiduronic acid; Indolyl 3-glucuronide; Indoxyl β-D-glucuronide. CAS No. 35804-66-1. Molecular formula: C14H15NO7. Mole weight: 309.27. | |
| 3-Indolyl b-D-glucuronide cyclohexylammonium salt | 3-Indolyl b-D-glucuronide cyclohexylammonium salt is a crucial reagent used in biomedical research. It serves as a substrate for β-glucuronidase, allowing the detection and quantification of glucuronidase activity in various tissues and biological samples. This compound facilitates the study of drug metabolism, as well as the diagnosis and monitoring of certain diseases, including liver disorders and cancers. Synonyms: Indoxyl b-D-glucuronide CHX salt; 1H-Indol-3-yl β-D-glucopyranosiduronic acid cyclohexylammonium salt; 3-Indolyl-β-D-glucuronide cyclohexylammonium salt; Indol-3-yl β-D-glucosiduronic acid cyclohexylammonium salt; Indolyl 3-glucuronide cyclohexylammonium salt; Indoxyl β-D-glucuronide cyclohexylammonium salt; β-D-Glucopyranosiduronic acid, 1H-indol-3-yl, compd. with cyclohexanamine (1:1). CAS No. 216971-58-3. Molecular formula: C14H15NO7.C6H13N. Mole weight: 408.45. | |
| 3-Indolyl-β-D-glucuronide cyclohexanamine | 3-Indolyl-β-D-glucuronide cyclohexanamine is the glucose component of X-Gluc staining buffer. 3-Indolyl-β-D-glucuronide cyclohexanamine can be used to detect gene expression. The active ingredient of the stain, β-Glucuronidase (GUS), reacts with the enzyme, causing the target gene to appear blue-purple in tissues or cells, so that the expression level and tissue distribution of the gene can be visually observed [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216971-58-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W154341. | |
| 4-Methylumbelliferyl 2,3,4-tri-O-acetyl-a-L-idopyranosiduronic acid methyl ester | 4-Methylumbelliferyl 2,3,4-tri-O-acetyl-a-L-idopyranosiduronic acid methyl ester is a pivotal compound widely utilized in the realm of biomedical exploration, serving as an invaluable substrate for identifying and quantifying the dynamicity of numerous enzyme systems, most notably glucuronidases. Synonyms: Methyl (4-methylumbelliferyl 2,3,4-tri-O-acetyl-a-L-idopyranosid)uronate. CAS No. 128095-50-1. Molecular formula: C23H24O12. Mole weight: 492.43. | |
| 4-Methylumbelliferyl 2-acetamido-2-deoxy-4-O-(a-L-fucopyranosyl)-b-D-glucopyranoside | 4-Methylumbelliferyl 2-acetamido-2-deoxy-4-O-(a-L-fucopyranosyl)-b-D-glucopyranoside is a specialized compound commonly employed in biomedical research. This product is utilized for the detection and measurement of glycosidase activity, particularly the enzymes involved in carbohydrate metabolism. It serves as a substrate for assaying β-galactosidase, β-glucuronidase, and β-glycosidase activities, aiding in the investigation of various diseases related to carbohydrate-processing deficiencies such as lysosomal storage disorders. Synonyms: Fuc-a-1,4-GlcNAc-b-4MU; 7-[[2-(Acetylamino)-2-deoxy-4-O-(6-deoxy-α-L-galactopyranosyl)-β-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one; 4-Methylumbelliferyl 2-acetamido-2-deoxy-4-O-(α-L-fucopyranosyl)-β-D-glucopyranoside. CAS No. 383160-13-2. Molecular formula: C24H31NO12. Mole weight: 525.50. | |
| 4-Methylumbelliferyl b-D-glucuronide trihydrate | 4-Methylumbelliferyl b-D-glucuronide trihydrate is a crucial biochemical compound serving as a substrate for the detection and quantification of β-glucuronidase activity. The enzymatic hydrolysis of this compound aids in the research of various diseases associated with β-glucuronidase deficiency, including Sly syndrome and hepatocellular carcinoma. Synonyms: MUG; 4-MU-b-D-GlcA; β-D-Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, trihydrate; 4-Methyl-2-oxo-2H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid trihydrate; 4-Methylumbelliferone glucuronide trihydrate; 4-Methylumbelliferone β-D-glucuronide trihydrate; 4-Methylumbelliferyl glucuronide trihydrate; 4-Methylumbelliferyl β-D-glucuronide trihydrate; 4-Methylumbelliferyl-β-D-glucuronic acid trihydrate; Hymecromon-7-O-4-β-D-glucuronide trihydrate. CAS No. 199329-67-4. Molecular formula: C16H16O9.3H2O. Mole weight: 406.34. | |
| 4-Methylumbelliferyl β-D-glucuronide | 4-Methylumbelliferyl-β-D-glucuronide is a fluorogenic substrate for β-glucuronidase. 4-Methylumbelliferyl-β-D-glucuronide is cleaved by β-glucuronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). Synonyms: MUG; 4-Methylumbelliferone β-D-Glucuronide; 4-Methyl-2-oxo-2H-1-benzopyran-7-yl β-D-Glucopyranosiduronic Acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid; MUGlcU; 2H-1-Benzopyran-2-one, 7-(β-D-glucopyranuronosyloxy)-4-methyl-; Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, β-D-; 4-Methylumbelliferone glucuronide; 4-Methylumbelliferyl glucuronide; 4-Methylumbelliferyl β-D-glucuronic acid; Hymecromon-7-O-4-β-D-glucuronide. Grade: ≥98%. CAS No. 6160-80-1. Molecular formula: C16H16O9. Mole weight: 352.29. | |
| 4-Methylumbelliferyl-β-D-glucuronide hydrate | 4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λ ex =362 nm, λ em =445 nm). 4-Methylumbelliferyl-β-D-glucuronide hydrate has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: MUG. CAS No. 881005-91-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-D0935A. | |
| 4-Methylumbelliferyl-β-D-Glucuronide hydrate | 4-Methylumbelliferyl-β-D-glucuronide is a fluorogenic substrate for β-glucuronidase. 4-Methylumbelliferyl-β-D-glucuronide is cleaved by β-glucuronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). Synonyms: β-D-Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, hydrate (1:x); 4-Methylumbelliferyl-β-D-Glucopyranosiduronic Acid hydrate; 4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid hydrate; 4-Methylumbelliferone glucuronide hydrate; 4-Methylumbelliferyl glucuronide hydrate; 4-Methylumbelliferyl β-D-glucuronic acid hydrate; Hymecromon-7-O-4-β-D-glucuronide hydrate. Grade: ≥95%. CAS No. 881005-91-0. Molecular formula: C16H16O9.xH2O. Mole weight: 352.29 (anhydrous basis). | |
| 4-Nitrophenyl a-D-glucuronide | 4-Nitrophenyl a-D-glucuronide is a key reagent used in biomedicine for studying glucuronidation reactions. It is a substrate for glucuronidases and is widely used for detecting and quantifying glucuronidation activity in drug metabolism studies. This product plays a crucial role in understanding the metabolism and elimination of drugs in the body, particularly those undergoing glucuronidation reactions. Synonyms: 4-Nitrophenyl α-D-glucopyranosiduronic acid; p-Nitrophenyl α-D-glucopyranosiduronic acid; p-Nitrophenyl α-D-glucopyranosyluronic acid; (2S,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-(4-nitrophenoxy)tetrahydro-2H-pyran-2-carboxylic acid. CAS No. 71484-85-0. Molecular formula: C12H13NO9. Mole weight: 315.23. | |
| 4-Nitrophenyl b-D-glucuronide sodium salt | 4-Nitrophenyl b-D-glucuronide sodium salt is a compound commonly used in the biomedical industry. It is primarily employed as a substrate for the detection and quantification of β-glucuronidase activity in various biological samples. This compound facilitates the study of drug metabolism and the detection of certain diseases related to impaired glucuronidation processes. Synonyms: β-D-Glucopyranosiduronic acid, 4-nitrophenyl, sodium salt (1:1); β-D-Glucopyranosiduronic acid, 4-nitrophenyl, monosodium salt; Sodium (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-nitrophenoxy)tetrahydro-2H-pyran-2-carboxylate; 4-Nitrophenyl β-D-glucopyranosiduronic acid sodium salt; 4-Nitrophenol glucuronide sodium salt; 4-Nitrophenyl β-D-glucosiduronic acid sodium salt; p-Nitrophenol β-D-glucuronide sodium salt; p-Nitrophenyl β-glucuronide sodium salt. CAS No. 89772-41-8. Molecular formula: C12H12NNaO9. Mole weight: 337.21. | |
| 4-Nitrophenyl β-D-glucuronide | 4-Nitrophenyl β-D-glucuronide (pNPG_1) is aderivative of 4-Nitrophenol. 4-Nitrophenyl β-D-glucuronide is the chromogenic substrate for β-glucuronidase [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: pNPG_1. CAS No. 10344-94-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W039892. | |
| 4-Nitrophenyl beta-D-glucuronide | 4-Nitrophenyl beta-D-glucuronide is a compound commonly used in the biomedical industry. It is primarily employed as a substrate for the detection and quantification of β-glucuronidase activity in various biological samples. This compound facilitates the study of drug metabolism and the detection of certain diseases related to impaired glucuronidation processes. Synonyms: 4-Nitrophenyl β-D-glucopyranosiduronic acid; Glucopyranosiduronic acid, p-nitrophenyl, β-D-; 4-Nitrophenol glucuronide; 4-Nitrophenyl glucuronide; 4-Nitrophenyl β-D-glucopyranosiduronate; 4-Nitrophenyl β-D-glucosiduronic acid; 4-Nitrophenyl β-D-glucuronide; p-Nitrophenol glucuronide; p-Nitrophenol β-D-glucuronide; p-Nitrophenol β-glucuronide; p-Nitrophenyl D-glucopyranosiduronic acid; p-Nitrophenyl glucosiduronic acid; p-Nitrophenyl glucuronic acid; p-Nitrophenyl glucuronide; p-Nitrophenyl β-D-glucopyranosiduronic acid; p-Nitrophenyl β-D-glucosiduronic acid; p-Nitrophenyl β-D-glucuronide; p-Nitrophenyl β-glucuronic acid; p-Nitrophenyl β-glucuronide. CAS No. 10344-94-2. Molecular formula: C12H13NO9. Mole weight: 315.23. | |
| 4-Trifluoromethylumbelliferyl b-D-glucuronide potassium salt | 4-Trifluoromethylumbelliferyl b-D-glucuronide potassium salt is a potent fluorescent substrate used in biomedicine to identify certain enzymes involved in drug metabolism. It specifically detects β-glucuronidase activity, an enzyme associated with various drug and disease metabolisms. Synonyms: β-D-Glucopyranosiduronic acid, 2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl, monopotassium salt; 4-Trifluoromethylumbelliferyl glucuronic acid, potassium salt; 2-Oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid monopotassium salt; Potassium (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-oxo-4-(trifluoromethyl)-2H-chromen-7-yloxy)tetrahydro-2H-pyran-2-carboxylate; Potassium 4-trifluoromethylumbelliferyl-β-D-glucuronide. CAS No. 143547-78-8. Molecular formula: C16H12F3O9K. Mole weight: 444.35. | |
| 5-Bromo-3-indolyl b-D-glucuronide cyclohexylammonium salt | 5-Bromo-3-indolyl β-D-glucuronide cyclohexylammonium salt is a highly significant chemical compound extensively employed in the biomedical domain, functioning as a remarkable substrate for the meticulous determination of β-glucuronidase activity.It considerably aids in the precise assessment and quantification of enzymatic levels. Synonyms: Blue glucuronide CHX; β-D-Glucopyranosiduronic acid, 5-bromo-1H-indol-3-yl, compd. with cyclohexanamine (1:1); 5-Bromo-3-indoxyl-beta-D-glucuronic acid cyclohexylammonium salt; 5-Bromo-1H-indol-3-yl β-D-glucopyranosiduronic acid cyclohexylammonium salt; 5-Bromo-3-indolyl-β-D-glucuronide cyclohexylammonium salt. CAS No. 199326-16-4. Molecular formula: C14H14BrNO7.C6H13N. Mole weight: 487.34. | |
| 5-Bromo-4-chloro-3-indolyl b-D-glucuronide cyclohexylammonium salt | 5-Bromo-4-chloro-3-indolyl b-D-glucuronide cyclohexylammonium salt is a highly specialized biochemical reagent, exclusively used for detecting β-glucuronidase activity. Widely researched and deployed, this reagent is proven to be particularly effective in detecting bacterial presence in samples associated with urinary tract infections. However, β-glucuronidase activity monitoring is not limited to urinary tract infections, as this salt has been shown to be useful in analyzing other tissues and diseases as well. Synonyms: X-Glucuronide; X-GlcA; X-GlcA CHX salt; β-D-Glucopyranosiduronic acid, 5-bromo-4-chloro-1H-indol-3-yl, compd. with cyclohexanamine (1:1); X-Gluc; 5-Bromo-4-chloro-1H-indol-3-yl β-D-glucopyranosiduronic acid cyclohexylammonium salt; 5-Bromo-4-chloro-3-indolyl-β-D-glucuronide cyclohexylammonium salt. CAS No. 114162-64-0. Molecular formula: C14H13BrClNO7.C6H13N. Mole weight: 521.79. | |
| 5-Bromo-4-chloro-3-indolyl b-D-glucuronide sodium salt | 5-Bromo-4-chloro-3-indolyl β-D-glucuronide sodium salt, renowned for its indispensable value in the biomedical sector, stands as a pivotal instrument. Its diverse applicability encompasses research pertaining to liver diseases and various cancer types, fueling the quest for heightened awareness about pharmaceutical substances. By serving as a substrate for β-glucuronidase activity detection, this exceptional product unveils a spectrum of possibilities for pharmaceutical and medical research, credited to its unparalleled solubility and stability attributes. Synonyms: β-D-Glucopyranosiduronic acid, 5-bromo-4-chloro-1H-indol-3-yl, sodium salt (1:1); Sodium 5-bromo-4-chloro-1H-indol-3-yl β-D-glucopyranosiduronate (1:1); β-D-Glucopyranosiduronic acid, 5-bromo-4-chloro-1H-indol-3-yl, monosodium salt; sodium (2S,3S,4S,5R,6S)-6-((5-bromo-4-chloro-1H-indol-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate. Grade: ≥95%. CAS No. 129541-41-9. Molecular formula: C14H12BrClNNaO7. Mole weight: 444.59. | |
| 5-Bromo-4-chloro-3-indolyl b-D-glucuronide sodium salt trihydrate | 5-Bromo-4-chloro-3-indolyl β-D-glucuronide sodium salt trihydrate is a valuable biochemical reagent widely used in the biomedical industry. It acts as a substrate for enzymes like β-glucuronidase, aiding in the detection and quantification of enzyme activity in various biological samples. This compound is especially helpful in studying drug metabolism, toxicity, and certain diseases such as liver disorders and cancer. Synonyms: X-Glucuronide trihydrate; X-GlcA Na; β-D-Glucopyranosiduronic acid, 5-bromo-4-chloro-1H-indol-3-yl, sodium salt, hydrate (1:1:3); β-D-Glucopyranosiduronic acid, 5-bromo-4-chloro-1H-indol-3-yl, monosodium salt, trihydrate; 5-Bromo-4-chloro-1H-indol-3-yl β-D-glucopyranosiduronic acid monosodium salt, trihydrate; 5-Bromo-4-chloro-3-indolyl-β-D-glucuronide monosodium salt, trihydrate. CAS No. 370100-64-4. Molecular formula: C14H12BrClNNaO7.3H2O. Mole weight: 498.64. | |
| 5-Bromo-6-chloro-3-indolyl b-D-glucuronide | 5-Bromo-6-chloro-3-indolyl b-D-glucuronide is a chemical compound widely used in the biomedicine industry. It is primarily employed as a substrate in lab experiments to detect the presence of β-glucuronidase. This enzyme is crucial for investigating drug metabolism and detecting certain diseases, such as bladder cancer and hereditary diseases like Sly syndrome. Synonyms: 5-Bromo-6-chloro-3-indolyl-b-D-glucopyranosiduronic acid; Magenta GlcA; 5-Bromo-6-chloro-1H-indol-3-yl β-D-glucopyranosiduronic acid; 5-Bromo-6-chloro-3-indolyl-β-D-glucuronide. CAS No. 144110-42-9. Molecular formula: C14H13BrClNO7. Mole weight: 422.61. | |
| 5-Bromo-6-chloro-3-indolyl b-D-glucuronide cyclohexylammonium salt | This product is a cyclohexylammonium salt of 5-Bromo-6-chloro-3-indolyl β-D-glucuronide. It is commonly used in the biomedical industry as a chromogenic substrate for β-glucuronidase enzyme assays. This assay helps in studying drug metabolism, specifically focusing on β-glucuronidase-mediated hydrolysis and drug-drug interactions. Synonyms: Magenta b-D-GlcA CHX; Magenta b-D-glucuronide CHX; β-D-Glucopyranosiduronic acid, 5-bromo-6-chloro-1H-indol-3-yl, compd. with cyclohexanamine (1:1); Magenta-β-D-GlcA; 5-Bromo-6-chloro-1H-indol-3-yl β-D-glucopyranosiduronic acid cyclohexanamine; 5-Bromo-6-chloro-3-indolyl-β-D-glucuronide cyclohexanamine. CAS No. 144110-43-0. Molecular formula: C14H13BrClNO7.C6H13N. Mole weight: 521.79. | |
| 6,8-Difluoro-4-methylumbelliferyl b-D-glucuronide | 6,8-Difluoro-4-methylumbelliferyl b-D-glucuronide is a vital recompound widely used in the biomedical industry for detecting glucuronidase activity. It serves as a highly sensitive substrate that reacting with the enzyme to produce a fluorescent signal. This compound enables the analysis of glucuronidase activity in various biological samples aiding in the research of diseases related to drug metabolism, liver function and lysosomal storage disorders. Synonyms: 6,8-Difluoro-4-methyl-2-oxo-2H-1-benzopyran-7-yl β-D-glucopyranosiduronic acid; (2S,3S,4S,5R,6S)-6-((6,8-difluoro-4-methyl-2-oxo-2H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. CAS No. 215868-36-3. Molecular formula: C16H14F2O9. Mole weight: 388.27. | |
| 6-Chloro-3-indolyl b-D-glucuronide sodium salt | 6-Chloro-3-indolyl b-D-glucuronide sodium salt, known for its significant contribution in the field of biomedical research, serves as an invaluable asset. Primarily utilized as a substrate for the purpose of β-glucuronidase detection and localization, this compound serves as a catalyst in the identification and analysis of drugs metabolized via glucuronidation. It assumes a pivotal role in the comprehensive examination of drug metabolism, intricate drug-drug interactions, and the pathogenesis of multifarious diseases. Synonyms: Rose glucuronide Na; β-D-Glucopyranosiduronic acid, 6-chloro-1H-indol-3-yl, sodium salt (1:1); β-D-Glucopyranosiduronic acid, 6-chloro-1H-indol-3-yl, monosodium salt; 6-Chloro-1H-indol-3-yl β-D-glucopyranosiduronic acid sodium salt; 6-Chloro-3-indolyl-β-D-glucuronide sodium salt. CAS No. 216971-56-1. Molecular formula: C14H13ClNNaO7. Mole weight: 365.70. | |
| 6-Chloro-3-indolyl-β-D-Glucuronide cyclohexylammonium salt | 6-Chloro-3-indolyl-β-D-Glucuronide cyclohexylammonium salt is the chromogenic substrate of β-glucuronidase used for histochemical analysis of β-glucuronidase activity. Synonyms: β-D-Glucopyranosiduronic acid, 6-chloro-1H-indol-3-yl, compd. with cyclohexanamine (1:1); Rose-β-D-GlcU CHA; Salmon-β-D-GlcU cyclohexylammonium salt; Salmon glca cyclohexylammonium salt; 6-Chloro-3-indolyl-β-D-glucuronic acid cyclohexylammonium salt; Rose glucuronide CHA. Grade: ≥95%. CAS No. 138182-20-4. Molecular formula: C14H14ClNO7.C6H13N. Mole weight: 442.89. | |
| Antileukinate | Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus. Antileukinate can inhibit acute lung injury by suppressing neutrophil mobilization induced by CXC-chemokines. It inhibits IL-8 binding to neutrophils, which prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. When antileukinate was added to melanoma cells, it inhibited the binding of MGSA/GROα. Synonyms: Interleukin-8 Inhibitor; N2-Acetyl-L-arginyl-L-arginyl-L-tryptophyl-L-tryptophyl-L-cysteinyl-L-argininamide; IL-8 (inhibitor). Grade: ≥95%. CAS No. 138559-60-1. Molecular formula: C45H66N18O7S. Mole weight: 1003.2. | |
| Bilirubin Conjugate, Sodium Salt | Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives. In vivo, bilirubin circulates in the plasma and is taken up by hepatocytes and conjugated to one or two glucuronic acids in a reaction catalyzed by UDP glucuronidase to form bilirubin mono or diglucuronide. This water-soluble form is then excreted from the liver in bile in the feces or is converted to urobilinogen and excreted in the urine. In addition to aiding in the disposal of heme, bilirubin and its conjugated derivatives have been shown to exhibit anti-oxidant and antimutagenic effects and to play a role in gut barrier function.1,2. Group: Molecular Biology. Alternative Names: 2,2'-[(2,17-diethenyl-1,10,11,19,22,23-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-diyl)bis[(1-oxo-3,1-propanediyl)imino]]bis-ethanesulfonic acid, disodium salt; Bilirubin Ditaurate. Grades: Molecular Biology Grade. CAS No. 68683-34-1. Molecular Formula: C37H44N6O10S2Na2, Molecular Weight: 842.91. US Biological Life Sciences. | Worldwide |
| D-Glucaro-1,5-lactam potassium salt | D-Glucaro-1,5-lactam potassium salt is a formidable antagonist against β-glucuronidase, acting as a paramount player in the realm of drug metabolism. Synonyms: (2R,3R,4S,5R)-3,4,5-Trihydroxy-6-oxo-2-piperidinecarboxylic acid potassium salt; D-Glucaro-delta-lactam potassium salt; 2-Piperidinecarboxylic acid, 3,4,5-trihydroxy-6-oxo-, potassium salt (1:1), (2S,3R,4S,5R)-; 2-Piperidinecarboxylic acid, 3,4,5-trihydroxy-6-oxo-, monopotassium salt, (2S,3R,4S,5R)-; 2-Piperidinecarboxylic acid, 3,4,5-trihydroxy-6-oxo-, monopotassium salt, [2S-(2α,3β,4α,5β)]-; Potassium D-glucaro-δ-lactam. CAS No. 53834-55-2. Molecular formula: C6H8KNO6. Mole weight: 229.23. | |
| D-Glucaro-delta-lactam potassium salt | D-Glucaro-delta-lactam potassium salt is a remarkable biomedical compound with capability to exert a potent anti-carcinogenic effect through the auspicious inhibition of beta-glucuronidase, a formidable enzyme known for its intricate involvement in both drug resistance and malignant tumor promotion. Synonyms: (2R,3R,4S,5R)-3,4,5-Trihydroxy-6-oxo-2-piperidinecarboxylic acid; D-Glucaro-delta-lactam. CAS No. 31675-02-2. Molecular formula: C6H9NO6. Mole weight: 191.14. | |
| D-Saccharic acid 1,4-lactone hydrate | D-Saccharic acid 1,4-lactone hydrate is an orally active β-glucuronidase inhibitor ( IC 50 =48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard agent compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61278-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134453A. | |
| Fluorescein di-b-D-glucuronide dimethyl ester | Fluorescein di-b-D-glucuronide dimethyl ester is a biomedical product widely used for studying drug metabolism. It serves as a substrate for glucuronidases, enzymes that metabolize various drugs in the body. With its fluorescent properties, it allows for efficient detection and measurement of drug metabolism in vitro and in vivo. Synonyms: Dimethyl 6,6'-((3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl)bis(oxy))(2S,2'S,3S,3'S,4S,4'S,5R,5'R,6S,6'S)-bis(3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate). Grade: ≥90%. CAS No. 1356090-59-9. Molecular formula: C34H32O17. Mole weight: 712.61. | |
| Ganoderenic acid A | Ganoderenic acid A is a lanostane-type triterpene. Ganoderenic acid A is a potent inhibitor of β-glucuronidase. Ganoderenic acid A has a potent hepatoprotective effect against CCl4-induced liver injury [1]. Uses: Scientific research. Group: Natural products. CAS No. 100665-40-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2998. | |
| glycyrrhizin hydrolase | The enzyme from Aspergillus niger is specific for the hydrolysis of the triterpenoid glycoside glycyrrhizin from roots of Glycyrrhiza sp. Group: Enzymes. Synonyms: glycyrrhizinate β-glucuronidase; glycyrrhizin β-hydrolase; glycyrrhizinic acid hydrolase. Enzyme Commission Number: EC 3.2.1.128. CAS No. 102484-56-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3811; glycyrrhizin hydrolase; EC 3.2.1.128; 102484-56-0; glycyrrhizinate β-glucuronidase; glycyrrhizin β-hydrolase; glycyrrhizinic acid hydrolase. Cat No: EXWM-3811. | |
| Heparanase 1 from Human, Recombinant | Heparanase is an endo β-D-glucuronidase, which degrades heparan sulfate side chains of heparan sulfate proteoglycans (HSPGs) in the extracellular matrix. Heparanase plays an important role in ECM degradation, facilitating the migration and extravasation of tumor cells and inflammatory leukocytes. Upon degradation, heparanase releases growth factors and cytokines that stimulate cell proliferation and chemotaxis. Heparanase is a heterodimer comprised of a 50 kDa subunit harboring the active site and a 8 kDa subunit. It is produced as a latent 65 kDa precursor and proteolytically processed to its active form. Heparanase is highly expressed in myeloid leukocytes (i.e. neutrophils) in platelets and in human placenta. Human heparanase was found to be upregulated in various types of primary tumors, correlating in some cases with increased tumor invasiveness and vascularity and with poor prospective survival. Recombinant heparanase protein hpa1 is produced in cho cells. the protein is purified by several orthogonal chromatography steps. Applications: Positive control for western blot analysis. Group: Enzymes. Synonyms: Heparanase; Hpa1 heparan. HPA1. Storage: Store at -20°C, avoid repeated freeze-thaw cycles. Source: CHO. Species: Human. Heparanase; Hpa1 heparanase; Hpa1; heparanase 1; heparanase-1; C1A heparanase; HPSE; HPA1. Cat No: NATE-0843. | |
| Naphthol AS-BI ?-D-glucuronide | ?-glucuronidase substrate. Group: Fluorescence/luminescence spectroscopy. | |
| Phenolphthalein β-D-Glucuronide | Phenolphthalein β-D-Glucuronide is a commonly used glucuronide conjugate for β-glucuronidase measurements. Highly water-soluble. Group: Biochemicals. Grades: Highly Purified. CAS No. 15265-26-6. Pack Sizes: 100mg, 1g. Molecular Formula: C26H22O10, Molecular Weight: 494.45. US Biological Life Sciences. | Worldwide |
| Phenolphthalein ?-D-glucuronide | ?-glucuronidase substrate. Group: Fluorescence/luminescence spectroscopy. | |
| Phenolphthalein ?-D-glucuronide sodium salt | ?-glucuronidase substrate. Group: Fluorescence/luminescence spectroscopy. | |
| Phenolphthalein Glucuronide, Sodium Salt | Phenolphthalein Glucuronide, Sodium Salt is a substrate for β-glucuronidase. Group: Biochemicals. Grades: Highly Purified. CAS No. 6820-54-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C26H22O10; Na, Molecular Weight: 494.452298999999. US Biological Life Sciences. | Worldwide |
| Saccharic acid | Saccharic acid is a competitive inhibitor of β-glucuronidase. Saccharic acid considerably retards hydrolysis of the glucuronide of 'l-ortho-hydroxyphenylazo-2-naph-thol' by frozen mouse kidney sections, but has no effect on liver regeneration following damage and on growth in infant mice [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 87-73-0. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W345885. | |
| X-Gluc cyclohexanamine | X-Gluc cyclohexanamine is a dye reagent for the detection of β-glucuronidase ( GUS ), an enzyme produced by E. coli. X-Gluc cyclohexanamine can be used to detect E. coli contamination in food, water and the urinary tract ( GUS as a specific detection indicator). X-Gluc cyclohexanamine is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene , appears blue) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 114162-64-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15935B. | |
| X-Gluc Dicyclohexylamine | X-Gluc Dicyclohexylamine is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 18656-96-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-15935. | |
| X-Gluc sodium | X-Gluc sodium is a dye reagent for the detection of β-glucuronidase ( GUS ), an enzyme produced by E. coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract ( GUS as a specific detection indicator). X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene , appears blue) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 129541-41-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-15935C. | |
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