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Glutaryl coenzyme A lithium is a Glutaryl coenzyme A derivative. Glutaryl coenzyme A is an important endogenous metabolites. Glutaryl coenzyme A lithium can be used in HMG-CoA or Glutaryl-CoA related experiment. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 103192-48-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141474.
Glutaryl coenzyme A is an intermediate in the metabolism (catabolism) of the amino acids lysine and tryptophan. Glutaryl CoA is used as a substrate to study the specificity and kinetics of glutaryl-CoA dehydrogenases. Applications: An intermediate in the metabolism (catabolism) of the amino acids lysine and tryptophan. Group: Coenzymes. Synonyms: Glutaryl CoA. CAS No. 103192-48-9. Purity: ≥90%. Mole weight: 881.63. Appearance: Powder. Form: Solid. Glutaryl CoA; Glutaryl coenzyme A lithium salt; 103192-48-9. Cat No: COEC-053.
3-hydroxy-3-isohexenylglutaryl-CoA lyase
Also acts on the hydroxy derivative of farnesoyl-CoA. Group: Enzymes. Synonyms: β-hydroxy-β-isohexenylglutaryl CoA-lyase; hydroxyisohexenylglutaryl-CoA:acetatelyase; 3-hydroxy-3-isohexenylglutaryl coenzyme A lyase; 3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase; 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase. Enzyme Commission Number: EC 4.1.3.26. CAS No. 37290-69-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4906; 3-hydroxy-3-isohexenylglutaryl-CoA lyase; EC 4.1.3.26; 37290-69-0; β-hydroxy-β-isohexenylglutaryl CoA-lyase; hydroxyisohexenylglutaryl-CoA:acetatelyase; 3-hydroxy-3-isohexenylglutaryl coenzyme A lyase; 3-hydroxy-3-isohexenylglutaryl-CoA isopentenylacetoacetyl-CoA-lyase; 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA acetate-lyase. Cat No: EXWM-4906.
Antibiotic 1233B
It is a β-lactone antibiotic produced by the strain of Cephalosporium sp. It has a strong inhibitory effect on hydroxymethyl glutaryl coenzyme A (HMG-CoA) synthase. Synonyms: 1233B; 3,5,7-trimethyl-12-hydroxy-13-hydroxymethyl-2,4-tetradecadiendioic acid; 2,4-Tetradecadienedioic acid, 12-hydroxy-13-(hydroxymethyl)-3,5,7-trimethyl-. CAS No. 34668-58-1. Molecular formula: C18H30O6. Mole weight: 342.43.
glutarate-CoA ligase
GTP or ITP can act instead of ATP. Group: Enzymes. Synonyms: glutaryl-CoA synthetase; glutaryl coenzyme A synthetase. Enzyme Commission Number: EC 6.2.1.6. CAS No. 9023-68-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5708; glutarate-CoA ligase; EC 6.2.1.6; 9023-68-1; glutaryl-CoA synthetase; glutaryl coenzyme A synthetase. Cat No: EXWM-5708.
glutaryl-CoA dehydrogenase (acceptor)
The enzyme contains FAD. The anaerobic, sulfate-reducing bacterium Desulfococcus multivorans contains two glutaryl-CoA dehydrogenases: a decarboxylating enzyme (EC 1.3.8.6), and a nondecarboxylating enzyme (this entry). The two enzymes cause different structural changes around the glutaconyl carboxylate group, primarily due to the presence of either a tyrosine or a valine residue, respectively, at the active site. Group: Enzymes. Synonyms: GDHDes; nondecarboxylating glutaryl-coenzyme A dehydrogenase; nondecarboxylating glutaconyl-coenzyme A-forming GDH; glutaryl-CoA dehydrogenase (non-decarboxylating). Enzyme Commission Number: EC 1.3.99.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1434; glutaryl-CoA dehydrogenase (acceptor); EC 1.3.99.32; GDHDes; nondecarboxylating glutaryl-coenzyme A dehydrogenase; nondecarboxylating glutaconyl-coenzyme A-forming GDH; glutaryl-CoA dehydrogenase (non-decarboxylating). Cat No: EXWM-1434.
glutaryl-CoA dehydrogenase (ETF)
Contains FAD. The enzyme catalyses the oxidation of glutaryl-CoA to glutaconyl-CoA (which remains bound to the enzyme), and the decarboxylation of the latter to crotonyl-CoA (cf. EC 4.1.1.70, glutaconyl-CoA decarboxylase). FAD is the electron acceptor in the oxidation of the substrate, and its reoxidation by electron-transfer flavoprotein completes the catalytic cycle. The anaerobic, sulfate-reducing bacterium Desulfococcus multivorans contains two glutaryl-CoA dehydrogenases: a decarboxylating enzyme (this entry), and a non-decarboxylating enzyme that only catalyses the oxidation to glutaconyl-CoA (EC 1.3.99.32). Group: Enzymes. Synonyms: glutaryl coenzyme A dehydrogenase; glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating); glutaryl-CoA dehydrogenase. Enzyme Commission Number: EC 1.3.8.6. CAS No. 37255-38-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1413; glutaryl-CoA dehydrogenase (ETF); EC 1.3.8.6; 37255-38-2; glutaryl coenzyme A dehydrogenase; glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating); glutaryl-CoA dehydrogenase. Cat No: EXWM-1413.
Hymeglusin
It is a β-lactone antibiotic produced by the strain of Cephalosporium sp. It has a strong inhibitory effect on hydroxymethyl glutaryl coenzyme A (HMG-CoA) synthase. Synonyms: Hymeglusin; Antibiotic 1233A; 29066-42-0; L-659,699; (2E,4E,7R)-11-[(2R,3R)-3-(hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid; 2,4-Undecadienoic acid, 11-[(2R,3R)-3-(hydroxymethyl)-4-oxo-2-oxetanyl]-3,5,7-trimethyl-, (2E,4E,7R)-; Antibiotic F 244; (R,R)-Hymeglusin; L 659699; F 244; F-244; SCHEMBL613745; CHEMBL470269; GTPL5886; CHEBI:191049; DTXSID901318499; (R,2E,4E)-11-((2R,3R)-3-(hydroxymethyl)-4-oxooxetan-2-yl)-3,5,7-trimethylundeca-2,4-dienoic acid; HB3701; AKOS032946337; 2,4-Undecadienoic acid, 11-(3-(hydroxymethyl)-4-oxo-2-oxetanyl)-3,5,7-trimethyl-, (2R-(2-alpha(2E,4E,7R*),3-beta))-; HY-117430; CS-0065979; G13092; J-017379; Q27078398; 11-[3R-(hydroxymethyl)-4-oxo-2R-oxetanyl]-3,5,7R-trimethyl-2E,4E-undecadienoic acid. Grade: ≥95%. CAS No. 29066-42-0. Molecular formula: C29H28ClFN6O3. Mole weight: 563.
isohexenylglutaconyl-CoA hydratase
Also acts on dimethylacryloyl-CoA and farnesoyl-CoA. Group: Enzymes. Synonyms: 3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase; isohexenylglutaconyl coenzyme A hydratase; β-isohexenylglutaconyl-CoA-hydratase; 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase. Enzyme Commission Number: EC 4.2.1.57. CAS No. 37290-84-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5046; isohexenylglutaconyl-CoA hydratase; EC 4.2.1.57; 37290-84-9; 3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase; isohexenylglutaconyl coenzyme A hydratase; β-isohexenylglutaconyl-CoA-hydratase; 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase. Cat No: EXWM-5046.
Mevastatin
It is produced by the strain of Penicillum brevicompactum. It has weak anti-fungal activity and can inhibit the key enzyme (3-hydroxy-3-methyl glutaryl coenzyme A(HMGCoA) reductase) in the cholesterol biosynthesis pathway. It has been shown to lower cholesterol in animals and humans. It led the discovery of statins, lipid-lowering drugs. It is now used as a biochemical reagent. Uses: Hydroxymethylglutaryl-coa reductase inhibitors. Synonyms: Mevastatina; Mevastatine; Mevastatinum; ML-236B; Compactin; CS-500; CS 500; CS500; ML-236B; ML 236B; ML236B; Antibiotic ML 236B. Grade: >98%. CAS No. 73573-88-3. Molecular formula: C23H34O5. Mole weight: 390.51.
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