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| Product | Description | |
|---|---|---|
| glutathione peroxidase | A protein containing a selenocysteine residue. Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 lipoxygenase on phospholipids, can act as acceptor, but more slowly than H2O2 (cf. EC 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase). Group: Enzymes. Synonyms: GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase. Enzyme Commission Number: EC 1.11.1.9. CAS No. 9013-66-5. GSH-Px. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0511; glutathione peroxidase; EC 1.11.1.9; 9013-66-5; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase. Cat No: EXWM-0511. |  |
| Glutathione Peroxidase | Glutathione Peroxidase (GSH-Px; EC 1.11.1.9) belongs to the peroxidase family and is commonly used in biochemical research. Glutathione Peroxidase can catalyze reduced glutathione (GSH) to form a disulfide bridge with another glutathione molecule, convert it into oxidized glutathione (GSSG), and react with hydrogen peroxide or lipid peroxide reaction, reducing it to H 2 O. Glutathione Peroxidase is an effective antioxidant against oxidative stress [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSH-Px; EC 1.11.1.9. CAS No. 9013-66-5. Pack Sizes: 100 U. Product ID: HY-P2833. |  |
| GLUTATHIONE PEROXIDASE | Synonyms: GLUTATHIONE: HYDROGEN-PEROXIDE OXIDOREDUCTASE; GLUTATHIONE PEROXIDASE; GSH-PX; EC 1.11.1.9; glutathione peroxidase F. bov. erythro-cytes; Glutathione Peroxidase from bovine erythrocytes; Peroxidase, glutathione; GLUTATHIONE PEROXIDASE F. BOV. ERYTHRO-C YTES, ~1. CAS No. 9013-66-5. |  |
| Anti-Glutathione-S-Transferase (GST)-Peroxidase Conjugate antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. |  |
| glutathione amide-dependent peroxidase | This enzyme, which has been characterized from the proteobacterium Marichromatium gracile, is a chimeric protein, containing a peroxiredoxin-like N-terminus and a glutaredoxin-like C terminus. The enzyme has peroxidase activity towards hydrogen peroxide and several small alkyl hydroperoxides, and is thought to represent an early adaptation for fighting oxidative stress. The glutathione amide disulfide produced by this enzyme can be restored to glutathione amide by EC 1.8.1.16 (glutathione amide reductase). Group: Enzymes. Enzyme Commission Number: EC 1.11.1.17. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0498; glutathione amide-dependent peroxidase; EC 1.11.1.17. Cat No: EXWM-0498. | |
| Native Bovine Glutathione Peroxidase | Glutathione peroxidase is an enzyme which reduced lipid hydroperoxides into their corresponding alcohols. It also reduces free hydrogen peroxide in to water. In vivo it is responsible for protecting hemoglobin from oxidative breakdown. Applications: Glutathione peroxidase from bovine erythr ocytes was used as a positive control in cloning and characterization of full-length cdnas encoding two glutathione peroxidases (gpxs) from globodera rost ochiensis. it was used for the determination of glutathione peroxidase activity in human milk. Group: Enzymes. Synonyms: EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Enzyme Commission Number: EC 1.11.1.9. CAS No. 9013-66-5. Mole weight: mol wt 84.5 kDa. Activity: > 300 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing 25% sucrose and 2.5% dithiothreitol with sodium phosphate buffer salts. Source: Bovine erythr ocytes. Species: Bovine. EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Cat No: NATE-0322. | |
| Native Human Glutathione Peroxidase | Glutathione peroxidase is an enzyme which reduced lipid hydroperoxides into their corresponding alcohols. It also reduces free hydrogen peroxide in to water. In vivo it is responsible for protecting hemoglobin from oxidative breakdown. At the reported ph optimum of 8.8, we have found the activity to be approx. 10 times that at ph 7.0. however, to remain consistent with literature and avoid complications arising from non-enzymatic oxidation of gsh, our unit is defined at ph 7.0. Group: Enzymes. Synonyms: EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Enzyme Commission Number: EC 1.11.1.9. CAS No. 9013-66-5. GSH-Px. Activity: > 30 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing 25% sucrose, 3% dithiothreitol, and sodium phosphate buffer salts. Source: Human erythr ocytes. Species: Human. EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Cat No: NATE-0323. | |
| phospholipid-hydroperoxide glutathione peroxidase | A protein containing a selenocysteine residue. The products of action of EC 1.13.11.12 lipoxygenase on phospholipids can act as acceptors; H2O2 can also act, but much more slowly (cf. EC 1.11.1.9 glutathione peroxidase). Group: Enzymes. Synonyms: peroxidation-inhibiting protein; PHGPX; peroxidation-inhibiting protein:peroxidase,glutathione (phospholipid hydroperoxide-reducing); phospholipid hydroperoxide glutathione peroxidase; hydroperoxide glutathione peroxidase. Enzyme Commission Number: EC 1.11.1.12. CAS No. 97089-70-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0493; phospholipid-hydroperoxide glutathione peroxidase; EC 1.11.1.12; 97089-70-8; peroxidation-inhibiting protein; PHGPX; peroxidation-inhibiting protein:peroxidase,glutathione (phospholipid hydroperoxide-reducing); phospholipid hydroperoxide glutathione peroxidase; hydroperoxide glutathione peroxidase. Cat No: EXWM-0493. | |
| 1-Bromonapthalene | 1-Bromonapthalene is used in the preparation of N-aryl imidazoles and diaryl ethers. Also used in the preparations of glutathione peroxidase-like antioxidant activity of diaryl diselenides. Group: Biochemicals. Grades: Highly Purified. CAS No. 90-11-9. Pack Sizes: 5g, 10 g. Molecular Formula: C10H7Br. US Biological Life Sciences. |  Worldwide |
| (1R,3R)-RSL3 | (1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) ( ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1219810-15-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100218C. | |
| (1S,3R)-RSL3 | (1S,3R)-RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor with EC50 of 10 μM in cellular assay. It binds, inactivates GPX4 and thus mediates GPX4-regulated ferroptosis. Synonyms: RSL3; RSL3 (1S,3R-); 1S,3R-RSL3. Grades: 98%. CAS No. 1219810-16-8. Molecular formula: C23H21ClN2O5. Mole weight: 440.9. | |
| Avarol | Antibacterial against selected Gram-positive strains, antifungal. Anticancer compound. Antileukemic. Antimitotic agent. Antiviral compound. Inhibits HIV activity. Anti-inflammatory. Synovial phospholipase A2, cyclooxygenase and lipoxygenase inhibitor. Modulator of superoxide dismutase and glutathione peroxidase. Platelet aggregation inhibitor. Anti-psoriatic, mediated by inhibition of TNF-alpha generation and NF-kappaB activation. Group: Biochemicals. Alternative Names: NSC 306951. Grades: Highly Purified. CAS No. 55303-98-5. Pack Sizes: 1mg. Molecular Formula: C21H30O2. US Biological Life Sciences. | Worldwide |
| Ebselen | Ebselen, also known as SPI-1005, is an organoselenium compound with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administration of SPI-1005, this agent mimics the activity of glutathione peroxidase (GPx) and can utilize glutathione to reduce other unstable molecules, thus preventing the formation of reactive oxygen species (ROS) and reducing oxidative stress on the cell. In the cochlea, this agent may prevent drug-induced injury to the auditory hair cells thereby preventing hearing loss. GPx is the main antioxidant enzyme in the cochlea and protects the inner ear from loud sounds and biochemical damage. In addition, ebselen is able to inhibit the activity of many enzymes involved in inflammation. Synonyms: SPI-1005; SPI1005; SPI 1005; Ebselen; PZ 51; PZ51; PZ-51; DR3305; DR 3305; DR-3305. Grades: >98%. CAS No. 60940-34-3. Molecular formula: C13H9NOSe. Mole weight: 274.192. | |
| Ebselen | Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker [1] [2]. Ebselen potently inhibits M pro ( IC 50 =0.67 μM) and COVID-19 virus ( EC 50 =4.67 μM) [3].Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SPI-1005; PZ-51; CCG-39161. CAS No. 60940-34-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13750. | |
| Ebselen | Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker. Ebselen potently inhibits Mpro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM).Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-phenyl-2-benzisoselenazol-3(2h)-one;PZ51;2-phenyl-benzo[d]isoselenazol-3-one;2-PHENYL-1,2-BENZISOSELENAZOL-3(2H)-ONE;EBSELEN;EBSELEN (PZ51, 2-PHENYL-1,2-BENZISOSELEN AZOL-3(2H)-ONE);EBSELEN 99%;2-phenyl-1,2-benzisoselenazol-. Product Category: Inhibitors. Appearance: light yellow solid. CAS No. 60940-34-3. Molecular formula: C13H9NOSe. Mole weight: 274.18. Purity: 0.96. IUPACName: 2-phenyl-1,2-benzoselenazol-3-one. Canonical SMILES: C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2. ECNumber: 612-054-8. Product ID: ACM60940343. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Ebselen | Glutathione peroxidase mimetic. Peroxynitrite scavenger. Anti-inflammatory Antioxidant. Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+-ATPase and NADPH oxidase inhibitor. Antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 60940-34-3. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C13H9NOSe. US Biological Life Sciences. | Worldwide |
| Gamma-glutamylcysteine | Gamma-glutamylcysteine (γ-Glutamylcysteine), a dipeptide containing cysteine and glutamic acid, is a precursor to glutathione (GSH). Gamma-glutamylcysteine is a cofactor for glutathione peroxidase (GPx) to increase GSH levels [1]. Uses: Scientific research. Group: Natural products. Alternative Names: γ-Glu-Cys. CAS No. 636-58-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113402. | |
| Gamma-glutamylcysteine TFA | Gamma-glutamylcysteine (γ-Glutamylcysteine) TFA, an intermediate in glutathione (GSH) synthesis, is a dipeptide served as an essential cofactor for the antioxidant enzyme glutathione peroxidase (GPx). Gamma-glutamylcysteine TFA also upregulates the level of the anti-inflammatory cytokine IL-10 and reduces the levels of the pro-inflammatory cytokines ( TNF-α , IL-6 , and IL-1β ). Gamma-glutamylcysteine TFA attenuates the changes in metalloproteinase activity in oligomeric Aβ40-treated astrocytes [1]. Uses: Scientific research. Group: Natural products. Alternative Names: γ-Glutamylcysteine TFA. CAS No. 283159-88-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-113402A. | |
| glutathione amide reductase | A dimeric flavoprotein (FAD). The enzyme restores glutathione amide disulfide, which is produced during the reduction of peroxide by EC 1.11.1.17 (glutathione amide-dependent peroxidase), back to glutathione amide (it catalyses the reaction in the opposite direction to that shown). The enzyme belongs to the family of flavoprotein disulfide oxidoreductases, but unlike other members of the family, which are specific for NADPH, it prefers NADH. Group: Enzymes. Synonyms: GAR. Enzyme Commission Number: EC 1.8.1.16. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1642; glutathione amide reductase; EC 1.8.1.16; GAR. Cat No: EXWM-1642. | |
| Glutathione reductase from E. coli, Recombinant | Glutathione reductase (GR) is a crucial flavoenzyme in the antioxidant defense system. Reduced glutathione (GSH) is used by glutathione peroxidase to detoxify hydrogen peroxide and in the precess is converted to oxidized glutathione (GSSG). The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP+. The regenerated GSH is then available to detoxify more hydrogen peroxide. The enzyme uses FAD as a cofactor. GR and glutathione peroxidase may inhibit lipid peroxidation by functioning as antioxidant enzymes in sperm. Glutathione reductase shares a structural motif with a number of other proteins including aspartyl prote...e; GSSG reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase. Enzyme Commission Number: EC 1.8.1.7. CAS No. 9001-48-3. Purity: >95% as judged by SDS-PAGE. GR. Mole weight: 49.5 kDa. Activity: 35 U/mg protein, 98 U/ml. Storage: Glutathione reductase should be stored at 4 °C or and will remain stable up to 3 years if stored as specified. Form: 3.2 M ammonium sulphate. Source: E. coli. Species: E. coli. GR; glutathione reductase; glutathione reductase (NADPH); NADPH-glutathione reductase; GSH reductase; GSSG reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase. Cat No: NATE-1574. | |
| GXpep-3 | GXpep-3 is a novel polypeptide inhibitor of phospholipid hydroperoxidase glutathione peroxidase (GPX4). Currently GPX4 is found to be a target which selectively induces iron-dependent cell death (ferroptosis) in cancer cells that express mutant Ras. GXpep-3 is promisingly developed to be a antitumor drug. Uses: Antitumor. Synonyms: GXpep 3; GXpep3. | |
| L-Selenomethionine | L-Selenomethionine is the predominant food form of selenium with antioxidant activity. L-Selenomethionine has been shown to increase the activity of glutathione peroxidase in endothelial cells. It may be chemoprotective against certain cancers. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Selenomethionine; L-(+)-Selenomethionine; Selenium-L-methionine; L-Selenomethioninum; Seleno-L-methionine; H-Mse-OH; (2S)-2-amino-4-methylselanylbutanoic acid. Grades: 95%. CAS No. 3211-76-5. Molecular formula: C5H11NO2Se. Mole weight: 196.12. | |
| L-SelenoMethionine | L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 3211-76-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1000A. | |
| MJ33 lithium salt | MJ33 is a selective and reversible inhibitor of the acidic, calcium-independent (ai)PLA2 activity of Prdx6. Prdx6 is a bifunctional enzyme with both non-selenium glutathione peroxidase (Gpx) and PLA2 activities. Synonyms: 1-Hexadecyl-3-(trifluoroethyl)-sn-glycero-2-phosphomethanol, Li. Grades: ≥95%. CAS No. 1007476-63-2. Molecular formula: C22H43F3LiO6P. Mole weight: 498.5. | |
| Native Baker's yeast (S. cerevisiae) Glutathione Reductase | Glutathione reductase (GR) is a crucial flavoenzyme in the antioxidant defense system. Reduced glutathione (GSH) is used by glutathione peroxidase to detoxify hydrogen peroxide and in the precess is converted to oxidized glutathione (GSSG). The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP+. The regenerated GSH is then available to detoxify more hydrogen peroxide. The enzyme uses FAD as a cofactor. GR and glutathione peroxidase may inhibit lipid peroxidation by functioning as antioxidant enzymes in sperm. Glutathione reductase shares a structural motif with a number of other proteins including aspartyl ...reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase. Enzyme Commission Number: EC 1.6.4.2. CAS No. 9001-48-3. GR. Mole weight: mol wt 118 kDa. Activity: 100-300 units/mg protein (biuret). Storage: 2-8°C. Form: ammonium sulfate suspension; Suspension in 3.6 M (NH4)2SO4, pH 7.0, containing 0.1 mM dithiothreitol. Source: Baker's yeast (S. cerevisiae). EC 1.6.4.2; 9001-48-3; Glutathione Reductase; GR; glutathione reductase; glutathione reductase (NADPH); NADPH-glutathione reductase; GSH reductase; GSSG reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase. Cat No: NATE-0317. | |
| Native Spinach Glutathione Reductase | Glutathione reductase (GR) is a crucial flavoenzyme in the antioxidant defense system. Reduced glutathione (GSH) is used by glutathione peroxidase to detoxify hydrogen peroxide and in the precess is converted to oxidized glutathione (GSSG). The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP+. The regenerated GSH is then available to detoxify more hydrogen peroxide. The enzyme uses FAD as a cofactor. GR and glutathione peroxidase may inhibit lipid peroxidation by functioning as antioxidant enzymes in sperm. Glutathione reductase shares a structural motif with a number of other proteins including aspartyl proteases, ...PH-glutathione reductase; GSH reductase; GSSG reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase. Enzyme Commission Number: EC 1.6.4.2. CAS No. 9001-48-3. GR. Mole weight: mol wt 118 kDa. Activity: 100-200 units/mg protein. Storage: 2-8°C. Form: ammonium sulfate suspension; Suspension in 3.6 M (NH4)2SO4 mM, 10 mM potassium phosphate, pH 7.0. Source: Spinach. EC 1.6.4.2; 9001-48-3; Glutathione Reductase; GR; glutathione reductase; glutathione reductase (NADPH); NADPH-glutathione reductase; GSH reductase; GSSG reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase. Cat No: NATE-0318. | |
| Native Wheat germ Glutathione Reductase | Glutathione reductase (GR) is a crucial flavoenzyme in the antioxidant defense system. Reduced glutathione (GSH) is used by glutathione peroxidase to detoxify hydrogen peroxide and in the precess is converted to oxidized glutathione (GSSG). The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP+. The regenerated GSH is then available to detoxify more hydrogen peroxide. The enzyme uses FAD as a cofactor. GR and glutathione peroxidase may inhibit lipid peroxidation by functioning as antioxidant enzymes in sperm. Glutathione reductase shares a structural motif with a number of other proteins including aspartyl proteases, Citrate synthase, EF hands, hemoglobins, lipecalins, and α/β hydrolases. GR is stimulated by melatonin and is reportedly irreversibly inhibited by a number of oxygen radical generating systems. Group: Enzymes. Synonyms: EC 1.6.4.2; 9. Enzyme Commission Number: EC 1.6.4.2. CAS No. 9001-48-3. GR. Mole weight: mol wt 118 kDa. Activity: > 0.08 units/mg protein. Storage: -20°C. Source: Wheat germ. EC 1.6.4.2; 9001-48-3; Glutathione Reductase; GR; glutathione reductase; glutathione reductase (NADPH); NADPH-glutathione reductase; GSH reductase; GSSG reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase. Cat No: NATE-0319. | |
| NOX Inhibitor VII, Thr101 (NADPH Oxidase Inhibitor VII, 6-Fluoro-2-o-tolylbenzo [d]isothiazol-3 (2H) -one, 6-Fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3(2H)-one) | A cell-permeable, selenium-to-sulfur substituted Ebselen derivative that exhibits similar NOX2 inhibitory activity as Ebselen by blocking p22phox c-terminal PRD (proline-rich domain) and p47phoxbis-SH3 interaction. Although less potent than Ebselen in cell-free p22phox PRD-p47phoxbis-SH3 binding (IC50 = 4 vs. 0.3uM) and NOX2 activity (IC50 = 4 vs. 0.6uM) assays, Thr101 is more potent and NOX2-selective than Ebselen in cell-based assays (Thr101 IC50 /Ebselen IC50 = 0.3/0.5, 3/0.15, 8/no inhibition, 8/0.7uM, respectively, against NOX2, NOX1, NOX4, and NOX5) and exhibits no glutathione peroxidase activity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??FNOS, Primary Target: Blocks p22phox c-terminal PRD (proline-rich domain) and p47phox bis-SH3 interaction. US Biological Life Sciences. | Worldwide |
| Oxidation-Reduction Compound Library | A unique collection of 1279 compounds with defined prooxidant or antioxidant activity can be used for HTS and HCS; - Contains hydroperoxides, polyphenolics, metal chelators, thiols, thiol traps, radical scavengers, lazaroids and glutathione modulators as well as small molecule enzyme mimetics for SOD and glutathione peroxidase, and antioxidant natural products, etc. ?- Structurally diversified with potent bioactivity and cell permeable; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2900. Categories: Oxidation-Reduction Compounds Libraries. |  |
| Probucol | Probucol (DH-581) is an anti-hyperlipidemic agent. Probucol activates glutathione peroxidase. Probucol promotes low density lipoprotein (LDL) catabolism, inhibits ABCA1-dependent cholesterol efflux, and decreases HDL-C levels. Probucol also has anti-inflammatory, antioxidant and neuroprotective properties. Probucol can be used for researches on bone, cardiovascular, cancer, neurological, and metabolism-related diseases [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DH-581. CAS No. 23288-49-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0388. | |
| proton-translocating NAD(P)+ transhydrogenase | The enzyme is a membrane bound proton-translocating pyridine nucleotide transhydrogenase that couples the reversible reduction of NADP by NADH to an inward proton translocation across the membrane. In the bacterium Escherichia coli the enzyme provides a major source of cytosolic NADPH. Detoxification of reactive oxygen species in mitochondria by glutathione peroxidases depends on NADPH produced by this enzyme. Group: Enzymes. Synonyms: pntA (gene name); pntB (gene name); NNT (gene name). Enzyme Commission Number: EC 7.1.1.1 (Formerly EC 1.6.1.5). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1578; proton-translocating NAD(P)+ transhydrogenase; EC 1.6.1.5; pntA (gene name); pntB (gene name); NNT (gene name). Cat No: EXWM-1578. | |
| S-Hexylglutathione | S-Hexylglutathione is an S-substituted glutathione in which the hydrogen of the thiol has been replaced by a hexyl group. S-Hexylglutathione is also an competitive inhibitor against glutathione-S-transferase. S-Hexylglutathione can be used as an affinity chromatographic ligand for glutathione-S-transferase and glutathione peroxidase [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24425-56-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W013754. | |
| Superoxide Dismutase A from Bacterial, Recombinant | Superoxide dismutase, Mn, also known as sodA, is a member of the iron/manganese superoxide dismutase family. SodA destroys radicals which are normally produced within the cells and which are toxic to biological systems. It works by catalyzing the dismutation of the superoxide radical O2- to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase. Group: Enzymes. Enzyme Commission Number: EC 1.15.1.1. Purity: > 95% by SDS-PAGE. SOD. Mole weight: 25.2 kDa (226 aa, 1-206 aa + His Tag). Activity: >350 units/mg. Form: Liquid. Source: E. coli. Species: Bacterial. Cat No: NATE-1659. | |
| Trigonelline Hydrochloride | Trigonelline is a pyridine alkaloid found in various edible seeds and legumes, including coffee. It is a zwitterion formed by the methylation of the nitrogen atom of niacin (vitamin B3; nicotinic acid) and, as a product of niacin metabolism, is excreted in urine of mammals.1 Trigonelline has been used to reduce blood glucose levels and to inhibit PPARγ expression in rat models of diabetes.2,3 It is also reported to inhibit the migration of hepatocarcinoma cells and render them more susceptible to apoptosis by reducing Raf/ERK/Nrf2 protein levels and activities of anti-oxidative enzymes further downstream, such as SOD, catalase, and glutathione peroxidase.4,5. Group: Biochemicals. Alternative Names: 1-Methylpyridinium-3-carboxylate hydrochloride; N-Methylnicotinic acid betaine hydrochloride. Grades: Plant Grade. CAS No. 6138-41-6. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C7H8ClNO2, Molecular Weight: 173.6. US Biological Life Sciences. | Worldwide |
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