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Glyburide (Glibenclamide) is an anti-diabetic compound in a class of medications known as sulfonylureas, closely related to sulfa agents. Grade: >98%. CAS No. 10238-21-8. Molecular formula: C23H28ClN3O5S. Mole weight: 494.
Glyburide
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
A second generation sulfonylurea with hypoglycemic activity. Group: Biochemicals. Alternative Names: 5-Chloro-N- [2- [4- [ [ [ (cyclohexylamino) carbonyl] amino] sulfonyl] phenyl] ethyl] -2-methoxybenzamide-d11, Adiab-d11, Azuglucon-d11, Bastiverit-d11, Glibenclamide-d11, Glidiabet-d11, Glimidstada-d11. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Glyburide-[d3]
Glyburide-[d3] is the labelled analogue of Glyburide. Glyburide is an antidiabetic drug. Synonyms: Glyburide D3; 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-(methoxy-d3)-benzamide. Grade: 95% by HPLC; 95% atom D. CAS No. 1219803-02-7. Molecular formula: C23H25D3ClN3O5S. Mole weight: 497.02.
Glyburide Impurity E. Synonyms: 3,5-Dichloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide; UR 623; 3-Chloro Glyburide. Grade: > 95%. CAS No. 57334-89-1. Molecular formula: C23H27Cl2N3O5S. Mole weight: 528.46.
Glyburide potassium salt
Glyburide is a sulfonylurea receptor 1 (SUR1) inhibitor linked to ATP-sensitive potassium channel Kir6.2 with an IC50 value of 4.3 nM. Synonyms: Glibenclamide; 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-benzamide, monopotassium salt. Grade: ≥98%. CAS No. 52169-36-5. Molecular formula: C23H28ClN3O5S·K. Mole weight: 533.1.
Glyburide Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Glyburide Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin secretion. Group: Biochemicals. Grades: Highly Purified. CAS No. 10238-21-8. Pack Sizes: 500mg, 1g. US Biological Life Sciences.
Worldwide
(rac)-cis-3-Hydroxy Glyburide
(rac)-cis-3-Hydroxy Glyburide is a metabolite of Glyburide. Synonyms: 3-cis-Hydroxycyclohexyl glyburide; 5-Chloro-N-[2-[4-[[[[(cis-3-hydroxycyclohexy)]amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide; cis-3-Hydroxyglyburide; cis-1-[[p-[2-(5-Chloro-o-anisaMido) ethyl]phenyl]sulfonyl]-3-(3-hydroxycyclohexyl)urea; re. Grade: > 95%. CAS No. 23074-02-4. Molecular formula: C23H28ClN3O6S. Mole weight: 510.01.
rac cis-3-Hydroxy Glyburide
rac cis-3-Hydroxy Glyburide is a metabolite of Glyburide which is used as an antidiabetic (MII-metabolite). Group: Biochemicals. Alternative Names: rel-5-Chloro-N- [2- [4- [ [ [ [ [ (1R, 3S) -3-hydroxycyclohexyl] amino] carbonyl] amino] sulfonyl] phenyl] ethyl] -2-methoxybenzamide; cis-1-[[p-[2- (5-Chloro-o-anisamido) ethyl]phenyl]sulfonyl]-3- (3-hydroxycyclohexyl) urea; 3-cis-Hydroxycyclohexyl Glyburide; 3-cis-Hydroxyglibenclamide; cis-3-Hydroxyglyburide. Grades: Highly Purified. CAS No. 23074-02-4. Pack Sizes: 1mg. US Biological Life Sciences.
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rac cis-3-Hydroxy Glyburide-[13C,d3]
rac cis-3-Hydroxy Glyburide-[13C,d3] is the labelled analogue of rac cis-3-Hydroxy Glyburide. rac cis-3-Hydroxy Glyburide is a metabolite of Glyburide which is used as an antidiabetic. Uses: A labelled metabolite of glyburide which is used as an antidiabetic, (labelled mii-metabolite). Synonyms: rac cis-3-Hydroxy Glyburide 13C,d3. Grade: 95% atom D; 95% atom 13C. CAS No. 1217848-91-3. Molecular formula: C22[13C]H25D3ClN3O6S. Mole weight: 514.01.
rac cis-3-Hydroxy Glyburide-13C,d3
Labeled rac cis-3-Hydroxy Glyburide. rac cis-3-Hydroxy Glyburide is a metabolite of Glyburide which is used as an antidiabetic (labeled MII-metabolite). Group: Biochemicals. Alternative Names: el-5-Chloro-N- [2- [4- [ [ [ [ [ (1R, 3S) -3-hydroxycyclohexyl] amino] carbonyl] amino] sulfonyl] phenyl] ethyl] -2- (methoxy-13C, d3) benzamide; cis-1-[[p-[2- (5-Chloro-o-anisamido) ethyl]phenyl]sulfonyl]-3- (3-hydroxycyclohexyl) urea-13C, d3; 3-cis-Hydroxycyclohexyl Glyburide-13C,d3; 3-cis-Hydroxyglibenclamide-13C,d3; cis-3-Hydroxyglyburide-13C,d3. Grades: Highly Purified. CAS No. 1217848-91-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Rac cis-3-hydroxy glyburide-d3,13c
Rac cis-3-hydroxy glyburide-d3,13c. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Chloro-N-[2-[4-[[[[(3-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide-d3,13C. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Solid. CAS No. 1217848-91-3. Molecular formula: C2213CH25D3ClN3O6S. Mole weight: 514.01. Purity: 0.96. IUPACName: 5-chloro-N-[2-[4-[[(1S,3R)-3-hydroxycyclohexyl]carbamoylsulfamoyl]phenyl]ethyl]-2-(trideuteriomethoxy)benzamide. Canonical SMILES: COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCC(C3)O. Product ID: ACM1217848913. Alfa Chemistry ISO 9001:2015 Certified.
(rac)-trans-3-Hydroxy Glyburide
(rac)-trans-3-Hydroxy Glyburide is a metabolite of Glyburide. Synonyms: rel-5-chloro-N-[2-[4-[[[[[(1R,3R)-3-hydroxycyclohexyl]amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide; 3-trans-Hydroxycyclohexyl Glyburide. Grade: > 95%. CAS No. 586414-84-8. Molecular formula: C23H28ClN3O6S. Mole weight: 510.01.
Rac trans-4-hydroxy glyburide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-Chloro-N-[2-[4-[[[[(4-Hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl)ethyl]-2-methoxybenzamide; 4'-Hydroxyglibenclamide. Product Category: Heterocyclic Organic Compound. Appearance: White Solid. CAS No. 23155-00-2. Molecular formula: C23H28ClN3O6S. Mole weight: 510. Purity: 0.96. IUPACName: 5-chloro-N-[2-[4-[(4-hydroxycyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-2-methoxybenzamide. Canonical SMILES: COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)O. Product ID: ACM23155002. Alfa Chemistry ISO 9001:2015 Certified. Categories: 5-Chloro-N-[2-[4-[[[[(trans-4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide.
rac trans-4-Hydroxy Glyburide-13C,d3
Labeled rac trans-4-Hydroxy Glyburide. rac trans-4-Hydroxy Glyburide is a metabolite of Glyburide which is used as an antidiabetic. Group: Biochemicals. Alternative Names: 5-Chloro-N- [2- [4- [ [ [ [ (trans-4-hydroxycyclohexyl) amino] carbonyl] amino] sulfonyl] phenyl] ethyl] -2- (methoxy-13C, d3) benzamide; trans-1-[[p-[2- (5-Chloro-o-anisamido) ethyl]phenyl]sulfonyl]-3- (4-hydroxycyclohexyl) urea-13C, d3; 4-trans-Hydroxycyclohexyl Glyburide-13C,d3; 4-trans-Hydroxyglibenclamide-13C,d3; N-[4-[ β - (2- (Methoxy-13C, d3) -5-chlorobenzamido) ethyl]benzenesulfonyl]-N'- (trans-4-hydroxycyclohexyl) urea; trans-4-Hydroxyglyburide-13C,d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A metabolite of Glyburide which is used as an antidiabetic. Group: Biochemicals. Alternative Names: 5-Chloro-N- [2- [4- [ [ [ [ (4-hydroxycyclohexyl) amino] carbonyl] amino] sulfonyl] phenyl) ethyl] -2-methoxy-benzamide, 4-Hydroxyglibenclamide. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Glibenclamide Impurity A is an impurity arising in the synthesis of Glyburide. Synonyms: 5-chloro-2-methoxy-N-[2-(4-sulfamoylphenyl)ethyl]benzamide. Grade: > 95 %. CAS No. 16673-34-0. Molecular formula: C16H17ClN2O4S. Mole weight: 368.84.
A metabolite of Glyburide which is used as an antidiabetic. Synonyms: 4-Hydroxyglibenclamide; rac trans-4-Hydroxy Glyburide; 23155-00-2; rac cis-4-Hydroxy Glyburide; 23155-04-6; 132054-81-0; trans-4-Hydroxyglyburide; 4-trans-Hydroxyglibenclamide; 4-trans-Hydroxy-glibenclamide; 4-Hydroxyglyburide, trans-; 4-trans-Hydroxycyclohexyl Glyburide; 8J8OD7PL2J; rac-trans-4-hydroxy Glyburide; 5-chloro-N-[2-[4-[(4-hydroxycyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-2-methoxybenzamide; cis-5-Chloro-N-[2-[4-[[[[(4-hydroxycyclohexyl); aMino]carbonyl]aMino]sulfonyl]phenyl]ethyl]-2-MethoxybenzaMide; 5-Chloro-N-(4-(N-((4-hydroxycyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide. CAS No. 23155-00-2. Molecular formula: C23H28ClN3O6S. Mole weight: 510.
5-Chloro-N-(2-Phenylethyl)-2-Methoxy-Benzamide
5-Chloro-N-(2-Phenylethyl)-2-Methoxy-Benzamide is a metabolite of the antidiabetic, Glyburide. Synonyms: 5-Chloro-N-phenethyl-o-anisamide; N-Phenethyl-5-chloro-2-methoxybenzamide; 5-Chloro-2-methoxy-N-(2-phenylethyl)benzamide. Grade: > 95%. CAS No. 33924-49-1. Molecular formula: C16H16ClNO2. Mole weight: 289.76.
Dimethyl DL-glutamate hydrochloride
Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes. It also potentiates the insulinotropic potential of glyburide and glucagon-like peptide Dimethyl DL-glutamate is used as a cell-permeable form of glutamate in studies of glutamate action in β-cells. Synonyms: Glutamic acid dimethyl ester; Dimethyl 2-aminopentanedioate; Dimethyl 2-aminopentanedioate hydrochloride; H-DL-Glu(OMe)-OMe.HCl; H-DL-Glu(Ome)-Ome. Grade: ≥ 98% (HPLC). CAS No. 13515-99-6. Molecular formula: C7H13NO4·HCl. Mole weight: 211.6.
Glibenclamide
Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel ( K ATP ) inhibitor and can be used for the research of diabetes and obesity [1]. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of K ATP and inhibits the cystic fibrosis transmembrane conductance regulator protein ( CFTR ) [3]. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability [4]. Glibenclamide can induce autophagy [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glyburide. CAS No. 10238-21-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15206.
Glibenclamide potassium salt
Glibenclamide potassium salt is a salt form of Glibenclamide, a KATP channel blocker used for the treatment of type 2 diabetes. Glibenclamide binds to and inhibits the sulfonylurea receptor 1 (SUR1), the regulatory subunit of the ATP-sensitive potassium channels (KATP) in pancreatic β cells. Uses: Antidiabetic. Synonyms: Glibenclamide potassium salt; Glyburide potassium salt; 23047-14-5; dipotassium; 5-chloro-N-[2-[4-[(N-cyclohexyl-C-oxidocarbonimidoyl)sulfamoyl]phenyl]ethyl]-2-methoxybenzenecarboximidate; E99010; 5-chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide potassium. Grade: 99%. CAS No. 23047-14-5. Molecular formula: C23H26ClK2N3O5S. Mole weight: 570.18.
NLRP3-IN-2
NLRP3-IN-2, an intermediate substrate in the synthesis of glyburide, inhibits the formation of the NLRP3 inflammasome in cardiomyocytes and limits the infarct size following myocardial ischemia/reperfusion in the mouse, without affecting glucose metabolism [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16673-34-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W011082.
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