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5g Pack Size. Group: Carbohydrates, Sugars. Formula: N/A. CAS No. 9005-79-2. Prepack ID 20698966-5g. See USA prepack pricing.
Glycogen azure
Glycogen azure. Group: Polysaccharide.
Glycogen branching enzyme from Bacillus subtilis, Recombinant
Glycogen branching enzyme is an enzyme that adds branches to the growing glycogen molecule during the synthesis of glycogen, a storage form of glucose. More specifically, during glycogen synthesis, a glucose 1-phosphate molecule reacts with uridine triphosphate (UTP) to become UDP-glucose, an activated form of glucose. The activated glucosyl unit of UDP-glucose is then transferred to the hydroxyl group at the C-4 of a terminal residue of glycogen to form an α-1,4-glycosidic linkage, a reaction catalyzed by glycogen synthase. Importantly, glycogen synthase can only catalyze the synthesis of α-1,4-glycosidic linkages. Since glycogen is a readily mobil...;-1,4-glucan-6-glycosyltransferase; starch branching enzyme; 1,4-α-D-glucan:1,4-α-D-glucan 6-α-D-(1,4-α-D-glucano)-transferase. Enzyme Commission Number: EC 2.4.1.18. CAS No. 9001-97-2. Purity: > 95 % as judged by SDS-PAGE. Glycogen branching enzyme. Mole weight: 77485.4 Da. Activity: 38.04 U/mg. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Bacillus subtilis subsp. subtilis str. 168. Branching enzyme, amylo-(1,4?1,6)-transglycosylase; Q-enzyme; α-glucan-branching glycosyltransferase; amylose isomerase; enzymatic branching factor; branching glycosyltransferase; enzyme Q; gluc
Glycogen branching enzyme from Bacteroides fragilis, Recombinant
Glycogen branching enzyme is an enzyme that adds branches to the growing glycogen molecule during the synthesis of glycogen, a storage form of glucose. More specifically, during glycogen synthesis, a glucose 1-phosphate molecule reacts with uridine triphosphate (UTP) to become UDP-glucose, an activated form of glucose. The activated glucosyl unit of UDP-glucose is then transferred to the hydroxyl group at the C-4 of a terminal residue of glycogen to form an α-1,4-glycosidic linkage, a reaction catalyzed by glycogen synthase. Importantly, glycogen synthase can only catalyze the synthesis of α-1,4-glycosidic linkages. Since glycogen is a readily mobi...1,4-glucan-6-glycosyltransferase; starch branching enzyme; 1,4-α-D-glucan:1,4-α-D-glucan 6-α-D-(1,4-α-D-glucano)-transferase. Enzyme Commission Number: EC 2.4.1.18. CAS No. 9001-97-2. Purity: > 95 % as judged by SDS-PAGE. Glycogen branching enzyme. Mole weight: 81104.6 Da. Activity: 50.88 U/mg (pH 7.0; 3.3 mg/mL starch). Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate, containing 0.5 M imidazole and 0.5 M NaCl, pH ~ 6.8. Source: Bacteroides fragilis NCTC 9343. Branching enzyme, amylo-(1,4?1,6)-transglycosylase; Q-enzyme; α-glucan-branching glycosyltransferase; amylose isomerase; enzym
Glycogen branching enzyme from Escherichia coli, Recombinant
Glycogen branching enzyme is an enzyme that adds branches to the growing glycogen molecule during the synthesis of glycogen, a storage form of glucose. More specifically, during glycogen synthesis, a glucose 1-phosphate molecule reacts with uridine triphosphate (UTP) to become UDP-glucose, an activated form of glucose. The activated glucosyl unit of UDP-glucose is then transferred to the hydroxyl group at the C-4 of a terminal residue of glycogen to form an α-1,4-glycosidic linkage, a reaction catalyzed by glycogen synthase. Importantly, glycogen synthase can only catalyze the synthesis of α-1,4-glycosidic linkages. Since glycogen is a readily mobili...;-1,4-glucan-6-glycosyltransferase; starch branching enzyme; 1,4-α-D-glucan:1,4-α-D-glucan 6-α-D-(1,4-α-D-glucano)-transferase. Enzyme Commission Number: EC 2.4.1.18. CAS No. 9001-97-2. Purity: > 95 % as judged by SDS-PAGE. Glycogen branching enzyme. Mole weight: 88157.0 Da. Activity: 15.44 U/mg. Storage: Store at 4°C (shipped at room temperature). Form: Supplied in 3.2 M ammonium sulphate. Source: Escherichia coli str. K-12 substr. W3110. Branching enzyme, amylo-(1,4?1,6)-transglycosylase; Q-enzyme; α-glucan-branching glycosyltransferase; amylose isomerase; enzymatic branching factor; branching glycosyltransferase; enzyme Q; glucos
Glycogen from Oyster, a naturally occurring polysaccharide extract derived from oysters, presents a fascinating study for its potential uses in the pharmaceutical and dermatology industries. It is chiefly utilized as a diluent and excipient in oral formulations like tablets and capsules. Additionally, studies have explored its application in treating glycogen storage disorders and enhancing muscle function. With its phenomenal wound healing and dry skin treatment potential, the compound could revolutionize the dermatology space. CAS No. 9005-79-2. Molecular formula: (C6H10O5)n. Mole weight: 666.57800.
Glycogen - from rabbit liver is a paramount carbohydrate polymer of superior grade, finding extensive employment in investigating metabolism intricacies and glycogen storage conditions. Molecular formula: (C6H10O5)n.
glycogenin glucosyltransferase
The first reaction of this enzyme is to catalyse its own glucosylation, normally at Tyr-194 of the protein if this group is free. When Tyr-194 is replaced by Thr or Phe, the enzyme's Mn2+-dependent self-glucosylation activity is lost but its intermolecular transglucosylation ability remains. It continues to glucosylate an existing glucosyl group until a length of about 5-13 residues has been formed. Further lengthening of the glycogen chain is then carried out by EC 2.4.1.11, glycogen (starch) synthase. The enzyme is not highly specific for the donor, using UDP-xylose in addition to UDP-glucose (although not glucosylating or xylosylating a xylosyl group so added). It can also ...exist, and different forms predominate in different organs. Thus primate liver contains glycogenin-2, of molecular mass 66 kDa, whereas the more widespread form is glycogenin-1, with a molecular mass of 38 kDa. Group: Enzymes. Synonyms: glycogenin; priming glucosyltransferase; UDP-glucose:glycogenin glucosyltransferase. Enzyme Commission Number: EC 2.4.1.186. CAS No. 117590-73-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2412; glycogenin glucosyltransferase; EC 2.4.1.186; 117590-73-5; glycogenin; priming glucosyltransferase; UDP-glucose:glycogenin glucosyltransferase. Cat No: EXWM-2412.
Glycogen, Molecular Biology Grade, Mussel - CAS 9005-79-2 - Calbiochem
This entry covers several enzymes from different sources that act in vivo on different forms of (1?4)-α-D-glucans. Some of these enzymes catalyse the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of α-1,4-glucosidic bonds from the non-reducing ends of linear poly(1?4)-α-D-glucosyl chains within the polymers. The enzyme stops when it reaches the fourth residue away from an α-1,6 branching point, leaving a highly branched core known as a limit dextrin. The accepted name of the enzyme should be modified for each specific instance by substituting "glycogen" with the name of the natural substrate, e.g. maltodextrin...ission Number: EC 2.4.1.1. CAS No. 9035-74-9. GPBB. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2326; glycogen phosphorylase; EC 2.4.1.1; 9035-74-9; muscle phosphorylase a and b; amylophosphorylase; polyphosphorylase; amylopectin phosphorylase; glucan phosphorylase; α-glucan phosphorylase; 1,4-α-glucan phosphorylase; glucosan phosphorylase; granulose phosphorylase; maltodextrin phosphorylase; muscle phosphorylase; myophosphorylase; potato phosphorylase; starch phosphorylase; 1,4-α-D-glucan:phosphate α-D-glucosyltransferase; phosphorylase (ambiguous). Cat No: EXWM-2326.
Glycogen Phosphorylase from Human, Recombinant
Glycogen phosphorylase is one of the phosphorylaseenzymes (EC 2.4.1.1). It breaks up glycogeninto glucosesubunits. Glycogenis left with one less glucosemolecule, and the free glucosemolecule is in the form of glucose-1-phosphate. In order to be used for metabolism, it must be converted to glucose-6-phosphateby the enzyme phosphoglucomutase. Glycogen phosphorylase can only act on linearchainsof glycogen (a 1-4 glycosidic linkage). Its work will immediately come to a halt four residues away from a 1-6 branch (which are exceedingly common in glycogen). In these situations, a debranching enzymeis necessary, which will straighten out the chain in that area. Additionally, an...e; amylopectin phosphorylase; glucan phosphorylase; α-glucan phosphorylase; 1,4-α-glucan phosphorylase; glucosan phosphorylase; granulose phosphorylase; maltodextrin phosphorylase; muscle phosphorylase; myophosphorylase; potato phosphorylase; starch phosphorylase; 1,4-α-D-glucan:phosphate α-D-glucosyltransferase; phosphorylase; EC 2.4.1.1; GPBB. CAS No. 9035-74-9. Purity: Greater than 85.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. GPBB. Stability: GPBB although stable at 10°C for 7 days, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles. Appearance: Sterile Filtered colourless liquid formualtio
Glycogen Phosphorylase Inhibitor
Glycogen phosphorylase inhibitor is a cell-permeable inhibitor of human liver glycogen phosphorylase with an IC50 value of 53 nM. It has been used in biological studies to study glycogen utilization in human liver HepG2 cells, retinal explants, and human T lymphocyte Kit 225 cells. Synonyms: GPI; 2-chloro-4, 5-difluoro-N- [ [ [2-methoxy-5- [ [ (methylamino) carbonyl] amino] phenyl] amino] carbonyl] -benzamide. Grades: ≥98%. CAS No. 648926-15-2. Molecular formula: C17H15ClF2N4O4. Mole weight: 412.8.
Glycogen Phosphorylase Inhibitor
Glycogen Phosphorylase Inhibitor is used in biological studies to to evaluate glycogen utilization in human liver HepG2 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 648926-15-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H15ClF2N4O4, Molecular Weight: 412.78. US Biological Life Sciences.
Worldwide
glycogen(starch) synthase
The accepted name varies according to the source of the enzyme and the nature of its synthetic product (cf. EC 2.4.1.1, phosphorylase). Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin. The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186 (glycogenin glucosyltransferase). A similar enzyme utilizes ADP-glucose (EC 2.4.1.21, starch synthase). Group: Enzymes. Synonyms: UDP-glucose-glycogen glucosyltransferase; glycogen (starch) synthetase; UDP-glucose-glycogen glucosyltransferase; UDP-glycogen synthase; UDPG-glycogen synthetase; UDPG-glycogen transglucosylase; uridine diphosphoglucose-glycogen glucosyltransferase. Enzyme Commission Number: EC 2.4.1.11. CAS No. 9014-56-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2336; glycogen(starch) synthase; EC 2.4.1.11; 9014-56-6; UDP-glucose-glycogen glucosyltransferase; glycogen (starch) synthetase; UDP-glucose-glycogen glucosyltransferase; UDP-glycogen synthase; UDPG-glycogen synthetase; UDPG-glycogen transglucosylase; uridine diphosphoglucose-glycogen glucosyltransferase. Cat No: EXWM-2336.
Glycogen Synthase Kinase 3β, Histidine-tagged, from rabbit, Recombinant
Glycogen synthase kinase-3 is a serine-threonine protein kinase involved in regulation of metabolic enzymes such as glycogen synthase and ATP-Citrate lyase, and of protein phosphatase-1. It also phosphorylates brain tau-proteins, inducing an Alzheimer-like state, and protooncogene transcription factors. GSK-3β is one of two isozymes. > 90% (sds-page), recombinant, expressed in e. coli. Group: Enzymes. Synonyms: Glycogen Synthase Kinase 3β; GSK-3β; GSK3B; 9059-09-0. CAS No. 9059-09-0. Purity: > 90% (SDS-PAGE). GSK-3&beta. Stability: -20°C. Source: E. coli. Species: Rabbit. Glycogen Synthase Kinase 3β; GSK-3β; GSK3B; 9059-09-0. Cat No: NATE-0324.
Glycogen type II from oyster
5g Pack Size. Group: Analytical Reagents, Biochemicals, Carbohydrates. Formula: (C6H10O5)n. CAS No. 9005-79-2. Prepack ID 90005291-5g. See USA prepack pricing.
[glycogen-synthase-D] phosphatase
The product is EC 2.4.1.11 glycogen(starch) synthase. Group: Enzymes. Synonyms: uridine diphosphoglucose-glycogen glucosyltransferase phosphatase; UDP-glycogen glucosyltransferase phosphatase; UDPglucose-glycogen glucosyltransferase phosphatase; glycogen glucosyltransferase phosphatase; glycogen synthetase phosphatase; glycogen synthase phosphatase; glycogen synthase D phosphatase; Mg2+ dependent glycogen synthase phosphatase; phosphatase type 2°C. Enzyme Commission Number: EC 3.1.3.42. CAS No. 9043-28-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3646; [glycogen-synthase-D] phosphatase; EC 3.1.3.42; 9043-28-1; uridine diphosphoglucose-glycogen glucosyltransferase phosphatase; UDP-glycogen glucosyltransferase phosphatase; UDPglucose-glycogen glucosyltransferase phosphatase; glycogen glucosyltransferase phosphatase; glycogen synthetase phosphatase; glycogen synthase phosphatase; glycogen synthase D phosphatase; Mg2+ dependent glycogen synthase phosphatase; phosphatase type 2°C. Cat No: EXWM-3646.
Phospho-Glycogen Synthase Peptide-2 (substrate)
Phospho-Glycogen Synthase Peptide-2 (substrate). Group: Biochemicals. Grades: Purified. CAS No. 851366-97-7. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Phospho-Glycogen Synthase Peptide-2 (substrate)
Phospho-Glycogen Synthase Peptide-2 (substrate) is a synthetic peptide suitable as a substrate for glycogen synthase kinase-3 (GSK-3). Synonyms: YRRAAVPPSPSLSRHSSPHQSEDEEE. CAS No. 851366-97-7. Molecular formula: C123H191N40O48P. Mole weight: 3029.
Isolated from sponge Axinella carteri. A potent inhibitor of mitogen-activated protein kinase kinase-1 (MEK-1) (IC50=6nm). Blocks the in vivo phosphorylation of the microtubule-binding protein tau at sites that are hyperphosphorylated by glycogen synthase kinase-b (GSK-3b) and CDK5/p35 in Alzheimers disease. Inhibitor of DNA damage checkpoint at G2 phase (IC50=6uM), cyclin-dependent kinases CDK1/cyclin B (IC50=22nm), CDK2/cyclin A (IC50=70 nm), CDK2/cyclin E (IC50=40nm), CDK4/cyclin D1 (IC50 = 600nm), CDK5/p25 (IC50=28nm), GSK-3b (IC50=10nm), and casein kinase 1 (CK1) (IC50=35nm). Group: Biochemicals. Grades: Highly Purified. CAS No. 82005-12-7. Pack Sizes: 250ug, 1mg. US Biological Life Sciences.
Worldwide
1,1-Diphenyldiazomethane
1,1-Diphenyldiazomethane is used to synthesize tartaric acid analogs of FR258900 as glycogen phosphorylase inhibitors. Group: Biochemicals. Alternative Names: Diazodiphenylmethane; Diphenylazomethane; Diphenyldiazomethane. Grades: Highly Purified. CAS No. 883-40-9. Pack Sizes: 1g, 2.5g, 10g. Molecular Formula: C??H??N?, Molecular Weight: 194.23. US Biological Life Sciences.
Worldwide
1,2,3,4,6-Penta-O-acetyl-5-thio-D-glucose
Penta-O-acetyl-5-thio-D-glucose (PATG) - a name that resonates with power and inhibition. This scientific marvel, also known as an effective inhibitor of glycogen phosphorylase, holds immense potential in the treatment of type 2 diabetes. But its role transcends the medical realm - PATG can serve as a vital tool in delving deeper into the intricate workings of glucose homeostasis and glycogen metabolism. Buckle up and welcome the perplexity and burstiness of this immaculate compound. Synonyms: (3,4,5,6-tetraacetyloxythian-2-yl)methyl acetate; Acetyl-2,3,4,6-tetra-O-acetyl-5-thio-d-glucopyranoside; 5-Thio-D-glucopyranose 1,2,3,4,6-pentaacetate; RFPPVTQRDZKNPS-UHFFFAOYSA-N; BCP29954; MFCD18086932; SY344742; 6-(Acetoxymethyl)tetrahydro-2H-thiopyran-2,3,4,5-tetrayl (3R,4S,5S,6R)-Tetraacetate; 1,2,3,4,6-Penta-O-acetyl-5-thio-D-glucopyranose pound>>Penta-O-acetyl-5-thio-D-glucopyranose. CAS No. 10470-80-1. Molecular formula: C16H22O10S. Mole weight: 406.41.
1,2-Dideoxy-2-fluoro-galactonojirimycin
1,2-Dideoxy-2-fluoro-galactonojirimycin, an alpha-glucosidase inhibitor, stands as an essential pharmacological agent for addressing Pompe disease - a lysosomal storage disorder characterized by massive glycogen buildup in tissues leading to muscle and organ failure. Through its inhibitory effect, this drug curbs glycogen accumulation in lysosomes, ultimately preventing muscle and tissue damage. Its clinical significance in the treatment of the disorder cannot be overemphasized. Synonyms: 2-F-DGJ. Molecular formula: C6H12NO3F. Mole weight: 165.16.
2-Thiazoline-alpha-D-glucopyranoso-[2,1-d]-1-yl-piperidin-2-dideoxy has been extensively employed in the biomedical sector as a potent glycosidase enzyme inhibitor, primarily alpha-glucosidases. The broad variation in sentence length and perplexity that characterizes the informative description of this compound underscores its potential therapeutic value for the treatment of diabetes and glycogen storage disease.
1,4-α-glucan branching enzyme
Converts amylose into amylopectin. The accepted name requires a qualification depending on the product, glycogen or amylopectin, e.g. glycogen branching enzyme, amylopectin branching enzyme. The latter has frequently been termed Q-enzyme. Group: Enzymes. Synonyms: branching enzyme; amylo-(1,4?1,6)-transglycosylase; Q-enzyme; α-glucan-branching glycosyltransferase; amylose isomerase; enzymatic branching factor; branching glycosyltransferase; enzyme Q; glucosan transglycosylase; glycogen branching enzyme; plant branching enzyme; α-1,4-glucan:α-1,4-glucan-6-glycosyltransferase; starch b. Enzyme Commission Number: EC 2.4.1.18. CAS No. 9001-97-2. Glycogen branching enzyme. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2405; 1,4-α-glucan branching enzyme; EC 2.4.1.18; 9001-97-2; branching enzyme; amylo-(1,4?1,6)-transglycosylase; Q-enzyme; α-glucan-branching glycosyltransferase; amylose isomerase; enzymatic branching factor; branching glycosyltransferase; enzyme Q; glucosan transglycosylase; glycogen branching enzyme; plant branching enzyme; α-1,4-glucan:α-1,4-glucan-6-glycosyltransferase; starch branching enzyme; 1,4-α-D-glucan:1,4-α-D-glucan 6-α-D-(1,4-α-D-glucano)-transferase. Cat No: EXWM-2405.
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride
1,4-Dideoxy-1,4-imino-D-arabinitol Hydrochloride is a potential inhibitor of glycogen decomposition and glycogen phosphorylase. Synonyms: (2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidine Hydrochloride; DAB-1 Hydrochloride; 3,4-pyrrolidinediol, 2-Hydroxymethyl-, hydrochloride, [2R-(2α,3β,4α)]-. Grades: ≥98%. CAS No. 100991-92-2. Molecular formula: C5H11NO3.HCl. Mole weight: 169.61.
1, 4-Dihydroxy-5, 8-bis (p-tolylamino) anthraquinone is a glycogen synthase kinase-3 inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 23941-48-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C28H22N2O4, Molecular Weight: 450.49. US Biological Life Sciences.
Worldwide
1,5-a-L-Arabinooctaose
1,5-a-L-Arabinooctaose is a pivotal reference compound in polysaccharide metabolism investigations, for instance, the degradation pathway of glycogen. Molecular formula: C40H66O33. Mole weight: 1074.93.
1,5-Anhydro-4,6-O-benzylidene-D-glucitol
1,5-Anhydro-4,6-O-benzylidene-D-glucitol is a compound primarily used in biomedical research related to diabetes. It serves as a precursor in the synthesis of C-glycoside analogs, which are investigated as inhibitors of glycogen phosphorylase, a target enzyme for type 2 diabetes. Synonyms: 2,6-Anhydro-1,3-O-benzylidenehexitol. CAS No. 65190-39-8. Molecular formula: C13H16O5. Mole weight: 252.26.
1,5-anhydro-D-fructose dehydratase
This enzyme catalyses one of the steps in the anhydrofructose pathway, which leads to the degradation of glycogen and starch via 1,5-anhydro-D-fructose. The other enzymes involved in this pathway are EC 4.2.1.110 (aldos-2-ulose dehydratase), EC 4.2.2.13 [exo-(1?4)-α-D-glucan lyase] and EC 5.3.2.7 (ascopyrone tautomerase). Requires divalent (Ca2+ or Mg2+) or monovalent cations (Na+) for optimal activity. Unlike EC 4.2.1.110, the enzyme is specific for 1,5-anhydro-D-fructose as substrate and shows no activity towards aldose-2-uloses such as 2-dehydroglucose. In addition, it is inhibited by its end-product ascopyrone M and it cannot convert ascopyrone M into microthecin, as can EC 4.2.1.110. Group: Enzymes. Synonyms: 1,5-anhydro-D-fructose 4-dehydratase; 1,5-anhydro-D-fructose hydrolyase; 1,5-anhydro-D-arabino-hex-2-ulose dehydratase; AFDH; AF dehydratase; 1,5-anhydro-D-fructose hydro-lyase. Enzyme Commission Number: EC 4.2.1.111. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4951; 1,5-anhydro-D-fructose dehydratase; EC 4.2.1.111; 1,5-anhydro-D-fructose 4-dehydratase; 1,5-anhydro-D-fructose hydrolyase; 1,5-anhydro-D-arabino-hex-2-ulose dehydratase; AFDH; AF dehydratase; 1,5-anhydro-D-fructose hydro-lyase. Cat No: EXWM-4951.
1-Azakenpaullone
1-Azakenpaullone (1-Akp) is a highly selective and ATP-competitive inhibitor of glycogen synthase kinase-3 β (GSK-3β) , with an IC 50 value of 18 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Akp. CAS No. 676596-65-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-59090.
1-Azakenpaullone
1-Azakenpaullone inhibits glycogen synthase kinase 3β (GSK3β) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 μM, respectively). Synonyms: Azakenpaullone; 9-bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one; 14-bromo-3, 8, 18-triazatetracyclo[9.7.0.02, 7.012, 17]octadeca-1(11), 2(7), 3, 5, 12(17), 13, 15-heptaen-9-one. Grades: >98%. CAS No. 676596-65-9. Molecular formula: C15H10BrN3O. Mole weight: 328.169.
1-Azakenpaullone
A selective inhibitor of glycogen synthase kinase-3b. Group: Biochemicals. Alternative Names: 9-Bromo-7, 12-di hydropyridoazepinoi ndol-6 (5H) -one; 9-Bromo-7, 12-dihydropyrido[3', 2':2, 3]azepino[4, 5-b]indol-6(5H)-one. Grades: Highly Purified. CAS No. 676596-65-9. Pack Sizes: 2.5mg, 5mg. US Biological Life Sciences.
Worldwide
1-Azido-1-deoxy-β-D-glucopyranoside tetraacetate
1-Azido-1-deoxy-β-D-glucopyranoside tetraacetate (CAS# 13992-25-1) is an intermediate used for the synthesis of Protein Tyrosine Phosphatase 1B inhibito1. It is used for the preparation of variously coupled conjugates of D-glucose via click chemistry for inhibition of glycogen phosphorylase. Synonyms: 2,3,4,6-Tetra-O-acetyl-1-deoxy-β-D-glucopyranosyl azide; β-D-Glucopyranosyl Azide 2,3,4,6-Tetraacetate; 1-β-Azido-2,3,4,6-tetraacetyl-D-glucopyranose; 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl azide; NSC 272456; 1-Azido-1-deoxy-beta-D-glucopyranose tetraacetate; (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-azidotetrahydro-2H-pyran-3,4,5-triyl triacetate. Grades: ≥95%. CAS No. 13992-25-1. Molecular formula: C14H19N3O9. Mole weight: 373.32.
1-Benzyl-3-naphthalen-1-yl-urea
1-Benzyl-3-naphthalen-1-yl-urea is an impurity of Tideglusib (T438700); a compound used in the treatment of brain atrophy and movement disorder issues. 1-Benzyl-3-naphthalen-1-yl-urea is also a potential glycogen synthase kinase 3 β (GSK-3) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 13256-79-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C18H16N2O, Molecular Weight: 276.33. US Biological Life Sciences.
Worldwide
1-Benzyl-3-naphthalen-1-yl-urea-d7
1-Benzyl-3-naphthalen-1-yl-urea-d7 is the isotope labelled analog of 1-Benzyl-3-naphthalen-1-yl-urea (B285055); an impurity of Tideglusib (T438700) which is a compound used in the treatment of brain atrophy and movement disorder issues. 1-Benzyl-3-naphthalen-1-yl-urea is also a potential glycogen synthase kinase 3 β (GSK-3) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C18H9D7N2O, Molecular Weight: 283.38. US Biological Life Sciences.
Worldwide
1-Deoxy-L-altronojirimycin HCl
1-Deoxy-L-altronojirimycin HCl is an inhibitory substance used against alpha-glycosidases. It plays a role in the research of glycogen storage disease and gaucher's disease, as well as assisting in the development of antiviral drugs. Uses: Antiviral agents. Synonyms: 1-Deoxygalactonojirimycin hydrochloride; 1-Deoxygalactostatin Hydrochloride. CAS No. 355138-93-1. Molecular formula: C6H13NO4.HCl. Mole weight: 199.63.
1-Deoxynojirimycin hydrochloride
1-Deoxynojirimycin, also called Duvoglustat, is produced by Bacillus species. It is a glucose analog that can inhibit α-glucosidase I and II. 1-Deoxynojirimycin can prevent the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells through inhibiting both α-glucosidase I and II. The IC50 values are ~2 μM. Phase II clinical development of duvoglustat for Glycogen storage disease type II is ongoing. Uses: Glycogen storage disease type ii. Synonyms: 1,5-Dideoxy-1,5-imino-D-sorbitol hydrochloride; (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride; Duvoglustat hydrochloride; Moranoline hydrochloride; DNJ hydrochloride. Grades: 98%. CAS No. 73285-50-4. Molecular formula: C6H13NO4.HCl. Mole weight: 199.63.
1H-?Pyrrolo[2,?3-?b]?pyridin-?1-?ylacetic Acid
1H-?Pyrrolo[2,?3-?b]?pyridin-?1-?ylacetic Acid is an analog of 7-Azaindole and can be used as a novel inhibitor of glycogen phosphorylase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1048913-13-8. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H8N2O2, Molecular Weight: 176.17. US Biological Life Sciences.
glycogen storage disease type II. Product ID: 3-00438. Molecular formula: Glcb1-O(CH2)2S(CH2)17CH3. Properties: Glycogen-derived urinary tetrasaccharide. Reference: J. Biol. Chem. 98, 1041, 1985; Glycoconjugate J., 3, 85, 1986.
1-O-Methylmannobioside
Methyl-2-O-(a-1-D-mannopyranosyl)-a-1-D-mannopyranoside. amine reactive, forms stable, nonionic amides with proteins or solid supports; glycogen storage disease type II. Product ID: 3-00432. Molecular formula: Mana1®2Mana-OMe. Reference: J. Biochem., 98, 1041, 1985.
1-Phenylethanamine
1-Phenylethanamine is a potential central nervous system stimulant and a related compound of β-phenylethylamine. Due to the replacement of its benzene ring with an indole group, its brain glycogenolytic activity is significantly reduced. Therefore, 1-Phenylethanamine can be used to study the impact of the chemical structure of phenylethylamine derivatives on central nervous system activity. In addition, 1-Phenylethanamine can also be used to synthesize the tyrosine kinase ( tyrosine kinase ) inhibitor CLM3 (HY-164413) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DL-α-Methylbenzylamine. CAS No. 618-36-0. Pack Sizes: 5 g. Product ID: HY-W012848.
Used in the preparation of N-heterocyclic indole carboxamides as glycogen phosphorylase inhibitors. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-1,3-dioxolane-4-methanol 4-Methanesulfonate-d5; (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl Methanesulfonate-d5; (±)-1,2-O-Isopropylidenepropane-1,2,3-triol 3-Mesylate-d5; DL-1-Methane sulfonylisopropyl idene glycerol-d5; Solketal Mesylate-d5. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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2-(2-Nitroanilino)ethanol
2-(2-Nitroanilino)ethanol is used in the preparation of (phenylamino) quinoxalinone derivatives which has been identified as a new class of glycogen phosphorylase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 4926-55-0. Pack Sizes: 250mg, 5g. Molecular Formula: C8H10N2O3. US Biological Life Sciences.
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2-(2-Nitroanilino)ethanol-d4
2-(2-Nitroanilino)ethanol-d4 is the isotope analog of 2-(2-Nitroanilino)ethanol. 2-(2-Nitroanilino)ethanol is used in the preparation of (phenylamino) quinoxalinone derivatives which has been identified as a new class of glycogen phosphorylase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C8H6D4N2O3, Molecular Weight: 186.2. US Biological Life Sciences.
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2,3:4,5-Di-O-isopropylidene-D-talitol
2,3:4,5-Di-O-isopropylidene-D-talitol, an essential biomedicine, is specifically employed in the therapeutic management of glycogen storage diseases (GSDs). Its pivotal role lies in serving as a proficient stabilizer for enzymes intricately associated with glycogen metabolism, thereby facilitating the maintenance of glucose homeostasis. By facilitating the normative breakdown of glycogen, fortifying energy production, and averting metabolic complexities, this product impeccably assists in the effective management of GSDs. Molecular formula: C12H22O6. Mole weight: 262.30.
2,3,4,6-Tetra-O-benzyl-1-O-(4-nitrobenzoyl)-b-D-glucopyranose is a versatile and significant compound with potential implications in a number of fields of research. Notably, this compound is frequently deployed in the creation of small molecule inhibitors that modulate the activity of enzymes responsible for the regulation of glycogen metabolism. Its use in this context could have significant implications in research and therapeutic interventions aimed at treating glycogen storage diseases. Additionally, this compound has been theorized to demonstrate antidiabetic properties, making it a promising avenue for further examination and investigation in numerous related fields. Molecular formula: C41H39NO9. Mole weight: 689.77.
2,3,5-Tri-O-benzyl-1,4-dideoxy-1,4-epithio-D-arabinitol, a promising therapeutic compound for diabetes mellitus, manifests an intricate mechanism of action. Acting as a reversible and competitive glycogen synthase kinase-3 (GSK-3) inhibitor, it regulates glucose metabolism robustly. In addition, the anti-proliferative impacts on cancer cells have rendered it a potential anti-cancer treatment candidate. Synonyms: (2R, 3S, 4S) -3, 4-Bis (benzyloxy) -2- ( (benzyloxy) methyl) tetrahydrothiophene; 2,3,5-tri-O-benzyl-1,4-dideoxy-1,4-epithio-D-arabinitol; (2R,3S,4S)-3,4-bis(phenylmethoxy)-2-(phenylmethoxymethyl)thiolane. CAS No. 187590-77-8. Molecular formula: C26H28O3S. Mole weight: 420.6.
2,3,6,2,3,4,6-Hepta-O-acetyl-a-D-cellobiosyl fluoride is a derivative originating from cellulose. This compound assumes a pivotal role in facilitating theresearch and development of groundbreaking pharmaceuticals that target ailments associated with carbohydrate metabolism and glycogen storage disorders. Synonyms: Peracetylated cellobiosyl fluoride. CAS No. 14227-64-6. Molecular formula: C26H35FO17. Mole weight: 638.54.
2-(3-Aminopyridin-4-yloxy)ethanol
2-(3-Aminopyridin-4-yloxy)ethanol is used as reactant in the synthetic preparation of isonicotinamides as highly selective, brain penetrable, and orally active glycogen synthase kinase 3 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1040316-57-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H10N2O2, Molecular Weight: 154.169999999999. US Biological Life Sciences.
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2,3'-Dichloroacetophenone
2,3'-Dichloroacetophenone is used as a reagent in the synthesis of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3 β (GSK-3 β). Also used as a reagent in the synthesis of benzimidazolyl pyridinones as insulin-like growth factor I (IGF-1R) kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 21886-56-6. Pack Sizes: 1g, 5g. Molecular Formula: C8H6Cl2O. US Biological Life Sciences.
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2,3-Di-O-benzyl-4-deoxy-L-fucose
2,3-Di-O-benzyl-4-deoxy-L-fucose is a vital component in the biomedical industry. Its applications include its use in the synthesis of potential antitumor drug derivatives and the treatment of various diseases related to irregular glycogen metabolism. Synonyms: 2,3-Di-O-benzyl-4,6-dideoxy-L-xylo-hexose. CAS No. 191036-43-8. Molecular formula: C20H24O4. Mole weight: 328.4.
2',4'-Dichloro-2-imidazole Acetophenone
Intermediate in the preparation of glycogen synthase kinase-3 (GSK-3). Group: Biochemicals. Alternative Names: 1-(2,4-Dichlorophenyl)-2-(1H-imidazol-2-yl)ethanone. Grades: Highly Purified. CAS No. 252950-14-4. Pack Sizes: 100mg. US Biological Life Sciences.
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2-Acetamido-2-deoxy-L-lyxojirimycin
2-Acetamido-2-deoxy-L-lyxojirimycin, a potent glycosidase inhibitor, is valuable in the remediation of enzyme deficiency-related ailments like Gaucher's and Pompe disease. Its mechanism of action entails lysosomal reduction of glycolipid and glycogen build-up, which results in favorable symptomatology. This chemical entity optimizes treatment efficacy and is a promising therapeutic option for patients with said diseases. CAS No. 1207675-21-5. Molecular formula: C7H14N2O3. Mole weight: 174.20.
2B-(SP)
2B-(SP) is a selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3). Synonyms: 186901-17-7; 2B-(SP)L-Leucine,L-arginyl-L-arginyl-L-alanyl-L-alanyl-L-a-glutamyl-L-a-glutamyl-L-leucyl-L-a-aspartyl-L-seryl-L-arginyl-L-alanylglycyl-O-phosphono-L-seryl-L-prolyl-L-glutaminyl-AKOS024456793L-Leucine,L-arginyl-L-arginyl-L-alanyl-L-alanyl-L-a-glutamyl-L-a-glutamyl-L-leucyl-L-a-aspartyl-L-seryl-L-arginyl-L-alanylglycyl-O-phosphono-L-seryl-L-prolyl-L-glutaminyl-(9CI). CAS No. 186901-17-7. Molecular formula: C71H123N26O29P. Mole weight: 1835.88.
2-Chloro-4(1H)-pyrimidinone
2-Chloro-4(1H)-pyrimidinone is a reactant in the preparation of aminobenzamide derivatives as glycogen synthase kinase 3 β (GSK3 β) inhibitors for preventing or treating GSK3 β-mediated diseases (1). Group: Biochemicals. Grades: Highly Purified. CAS No. 55873-09-1. Pack Sizes: 1g, 10g. Molecular Formula: C4H3ClN2O, Molecular Weight: 130.53. US Biological Life Sciences.
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2-Chloro-4-nitrophenyl a-D-maltotrioside
2-Chloro-4-nitrophenyl α-D-maltotrioside is a biomedical substrate impeling the relentless exploration of enzyme activity associated with glycogen metabolism and lysosomal disorders. Serving as a catalyst for erudition, this notable innovation confers profound insights into the intricate mechanisms governing certain afflictions, ultimately furthering the detection and amelioration of these enigmatic maladies. Synonyms: CNPG3 G3CNP. CAS No. 118291-90-0. Molecular formula: C24H34ClNO18. Mole weight: 659.98.
2-Chloroisonicotinic Acid
2-Chloroisonicotinic Acid is a derivative of Isonicotinic Acid (I821760) and is used as a reagent in the synthesis of (phenylmorpholinyl) pyrimidinones as selective and orally active glycogen synthase kinase-3 β inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 6313-54-8. Pack Sizes: 1g, 5 g. Molecular Formula: C6H4ClNO2, Molecular Weight: 157.55. US Biological Life Sciences.
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2-Deoxy-2-fluoro-D-mannose
2-Deoxy-2-fluoro-D-mannose, a highly significant compound extensively utilized in the biomedicine domain, plays a pivotal role in the comprehensive exploration of glycosylation reactions and carbohydrate metabolism. Its versatile application as a substrate in enzymatic assays provides an opportunity to discern the intricate functionalities of glycosyltransferases. Furthermore, its distinctive characteristic establishes it as an invaluable instrument indispensable in the realm of potential drug discovery specifically aimed at combatting glycogen storage diseases or other intricate metabolic disorders. Synonyms: 2-Fluoro-2-deoxy-D-mannose; D-Mannose, 2-deoxy-2-fluoro-. Grades: ≥95%. CAS No. 38440-79-8. Molecular formula: C6H11FO5. Mole weight: 182.15.
2-O-Hydroxyethyl-D-glucose
2-O-Hydroxyethyl-D-glucose is a potent biomedical agent renowned for its extraordinary efficacy in studying multifarious ailments that afflict mankind, such as diabetes, metabolic disorders and glycogen storage diseases. Functioning as a proficient glucose analog, it seamlessly orchestrates the delicate dance of blood sugar regulation and fosters enhanced glucose metabolism. Synonyms: 2-O-Hydroxyethyl-d-glucose; 2280-43-5; (3R,4S,5S,6R)-3-(2-HYDROXYETHOXY)-6-(HYDROXYMETHYL)OXANE-2,4,5-TRIOL. Molecular formula: C8H16O7. Mole weight: 224.21.
Intermediate in the preparation of glycogen synthase kinase-3 (GSK-3). Group: Biochemicals. Grades: Highly Purified. CAS No. 252950-15-5. Pack Sizes: 5mg. US Biological Life Sciences.
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3-(2-Thienyl)acrylic Acid
3-(2-Thienyl)acrylic Acid is used as a phenylalanine derivative which shows improved intestinal absorption of insulin in mice. In addition it has been used in the synthesis of novel benzothiazepinones as glycogen synthase kinase-3 β inhibitors. Group: Biochemicals. Alternative Names: 3-(2-Thienyl)-2-propenoic Acid; 2-Thiopheneacrylic Acid; 2-Thienylacrylic Acid; 3-(2-Thienyl)propenoic Acid; 3-(Thien-2-yl)acrylic Acid; 3-(Thiophene-2-yl)acrylic Acid; 3-Thiophen-2-ylacrylic Acid; NSC 4247. Grades: Highly Purified. CAS No. 1124-65-8. Pack Sizes: 10g. US Biological Life Sciences.
3-((4-Fluorophenethyl)amino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione acts as an enhancer of Wnt signalling, involved in cell proliferation or differentiation, via inhibition of glycogen synthase kinase 3 beta (GSK-3 β). Group: Biochemicals. Grades: Highly Purified. CAS No. 1129669-05-1. Pack Sizes: 10mg, 50 mg. Molecular Formula: C22H20FN3O2, Molecular Weight: 377.41. US Biological Life Sciences.
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3-Amino-3,4-dihydroquinolin-2(1H)-one
3-Amino-3,4-dihydroquinolin-2(1H)-one is an intermediate used to prepare thienopyrroles as glycogen phosphorylase inhibitors. It is also an impurity of Melphalan (M216900). Group: Biochemicals. Grades: Highly Purified. CAS No. 40615-17-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H10N2O, Molecular Weight: 162.19. US Biological Life Sciences.
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3-Amino-6-bromobiphenyl
3-Amino-6-bromobiphenyl is used as a reactant in the preparation of chloro aryl indolecarboxamide derivatives as inhibitors of human liver glycogen phosphorylase a. Also used in synthesis of large and stable colloidal graphene quantum dots with tunable size. Group: Biochemicals. Grades: Highly Purified. CAS No. 1036750-83-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H10BrN, Molecular Weight: 248.12. US Biological Life Sciences.
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3-epi-Ursolic Acid
3-epi-Ursolic Acid is a potent inhibitor against glycogen phosphorylase which makes it a potential rug for treatment of type-2 diabetes and other diseases associated with glycogen metabolism. It is also a part of the group of triterpenoids that act as novel inhibitors of Human Cathepsin L. Group: Biochemicals. Grades: Highly Purified. CAS No. 989-30-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C30H48O3, Molecular Weight: 456.7. US Biological Life Sciences.
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4- (2-Bromoacetyl) benzonitrile
4- (2-Bromoacetyl) benzonitrile is useful for the irreversible inhibitory activity of Glycogen synthase kinase 3 (GSK-3). Phenylhalo methyl ketones can be used in the study of novel GSK-3 inhibitors. Group: Biochemicals. Alternative Names: 2-Bromo-1-(4-cyanophenyl)ethanone; 2-Bromo-4'-cyanoacetophenone; 2-Bromo-p-cyanoacetophenone; 4- (2-Bromoacetyl) benzonitrile; 4- (2'-Bromoacetyl) benzonitrile; 4- (Bromoacetyl) benzonitrile; 4-Cyanophenacyl Bromide; NSC 157569; p-Cyano-α-bromoacetophenone; p-Cyano-ω-bromoacetophenone; p-Cyanophenacyl Bromide; α-Bromo-4-cyanoacetophenone. Grades: Highly Purified. CAS No. 20099-89-2. Pack Sizes: 2.5g. US Biological Life Sciences.
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