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Glycogen phosphorylase inhibitor is a cell-permeable inhibitor of human liver glycogen phosphorylase with an IC50 value of 53 nM. It has been used in biological studies to study glycogen utilization in human liver HepG2 cells, retinal explants, and human T lymphocyte Kit 225 cells. Synonyms: GPI; 2-chloro-4, 5-difluoro-N- [ [ [2-methoxy-5- [ [ (methylamino) carbonyl] amino] phenyl] amino] carbonyl] -benzamide. Grades: ≥98%. CAS No. 648926-15-2. Molecular formula: C17H15ClF2N4O4. Mole weight: 412.8.
Glycogen Phosphorylase Inhibitor
Glycogen Phosphorylase Inhibitor is used in biological studies to to evaluate glycogen utilization in human liver HepG2 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 648926-15-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H15ClF2N4O4, Molecular Weight: 412.78. US Biological Life Sciences.
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1,1-Diphenyldiazomethane
1,1-Diphenyldiazomethane is used to synthesize tartaric acid analogs of FR258900 as glycogen phosphorylase inhibitors. Group: Biochemicals. Alternative Names: Diazodiphenylmethane; Diphenylazomethane; Diphenyldiazomethane. Grades: Highly Purified. CAS No. 883-40-9. Pack Sizes: 1g, 2.5g, 10g. Molecular Formula: C??H??N?, Molecular Weight: 194.23. US Biological Life Sciences.
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1,2,3,4,6-Penta-O-acetyl-5-thio-D-glucose
Penta-O-acetyl-5-thio-D-glucose (PATG) - a name that resonates with power and inhibition. This scientific marvel, also known as an effective inhibitor of glycogen phosphorylase, holds immense potential in the treatment of type 2 diabetes. But its role transcends the medical realm - PATG can serve as a vital tool in delving deeper into the intricate workings of glucose homeostasis and glycogen metabolism. Buckle up and welcome the perplexity and burstiness of this immaculate compound. Synonyms: (3,4,5,6-tetraacetyloxythian-2-yl)methyl acetate; Acetyl-2,3,4,6-tetra-O-acetyl-5-thio-d-glucopyranoside; 5-Thio-D-glucopyranose 1,2,3,4,6-pentaacetate; RFPPVTQRDZKNPS-UHFFFAOYSA-N; BCP29954; MFCD18086932; SY344742; 6-(Acetoxymethyl)tetrahydro-2H-thiopyran-2,3,4,5-tetrayl (3R,4S,5S,6R)-Tetraacetate; 1,2,3,4,6-Penta-O-acetyl-5-thio-D-glucopyranose pound>>Penta-O-acetyl-5-thio-D-glucopyranose. CAS No. 10470-80-1. Molecular formula: C16H22O10S. Mole weight: 406.41.
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride
1,4-Dideoxy-1,4-imino-D-arabinitol Hydrochloride is a potential inhibitor of glycogen decomposition and glycogen phosphorylase. Synonyms: (2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidine Hydrochloride; DAB-1 Hydrochloride; 3,4-pyrrolidinediol, 2-Hydroxymethyl-, hydrochloride, [2R-(2α,3β,4α)]-. Grades: ≥98%. CAS No. 100991-92-2. Molecular formula: C5H11NO3.HCl. Mole weight: 169.61.
1,5-Anhydro-4,6-O-benzylidene-D-glucitol
1,5-Anhydro-4,6-O-benzylidene-D-glucitol is a compound primarily used in biomedical research related to diabetes. It serves as a precursor in the synthesis of C-glycoside analogs, which are investigated as inhibitors of glycogen phosphorylase, a target enzyme for type 2 diabetes. Synonyms: 2,6-Anhydro-1,3-O-benzylidenehexitol. CAS No. 65190-39-8. Molecular formula: C13H16O5. Mole weight: 252.26.
1H-?Pyrrolo[2,?3-?b]?pyridin-?1-?ylacetic Acid
1H-?Pyrrolo[2,?3-?b]?pyridin-?1-?ylacetic Acid is an analog of 7-Azaindole and can be used as a novel inhibitor of glycogen phosphorylase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1048913-13-8. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H8N2O2, Molecular Weight: 176.17. US Biological Life Sciences.
Used in the preparation of N-heterocyclic indole carboxamides as glycogen phosphorylase inhibitors. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-1,3-dioxolane-4-methanol 4-Methanesulfonate-d5; (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl Methanesulfonate-d5; (±)-1,2-O-Isopropylidenepropane-1,2,3-triol 3-Mesylate-d5; DL-1-Methane sulfonylisopropyl idene glycerol-d5; Solketal Mesylate-d5. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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2-(2-Nitroanilino)ethanol
2-(2-Nitroanilino)ethanol is used in the preparation of (phenylamino) quinoxalinone derivatives which has been identified as a new class of glycogen phosphorylase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 4926-55-0. Pack Sizes: 250mg, 5g. Molecular Formula: C8H10N2O3. US Biological Life Sciences.
Worldwide
2-(2-Nitroanilino)ethanol-d4
2-(2-Nitroanilino)ethanol-d4 is the isotope analog of 2-(2-Nitroanilino)ethanol. 2-(2-Nitroanilino)ethanol is used in the preparation of (phenylamino) quinoxalinone derivatives which has been identified as a new class of glycogen phosphorylase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C8H6D4N2O3, Molecular Weight: 186.2. US Biological Life Sciences.
Worldwide
3-Amino-3,4-dihydroquinolin-2(1H)-one
3-Amino-3,4-dihydroquinolin-2(1H)-one is an intermediate used to prepare thienopyrroles as glycogen phosphorylase inhibitors. It is also an impurity of Melphalan (M216900). Group: Biochemicals. Grades: Highly Purified. CAS No. 40615-17-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H10N2O, Molecular Weight: 162.19. US Biological Life Sciences.
Worldwide
3-Amino-6-bromobiphenyl
3-Amino-6-bromobiphenyl is used as a reactant in the preparation of chloro aryl indolecarboxamide derivatives as inhibitors of human liver glycogen phosphorylase a. Also used in synthesis of large and stable colloidal graphene quantum dots with tunable size. Group: Biochemicals. Grades: Highly Purified. CAS No. 1036750-83-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H10BrN, Molecular Weight: 248.12. US Biological Life Sciences.
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3-epi-Ursolic Acid
3-epi-Ursolic Acid is a potent inhibitor against glycogen phosphorylase which makes it a potential rug for treatment of type-2 diabetes and other diseases associated with glycogen metabolism. It is also a part of the group of triterpenoids that act as novel inhibitors of Human Cathepsin L. Group: Biochemicals. Grades: Highly Purified. CAS No. 989-30-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C30H48O3, Molecular Weight: 456.7. US Biological Life Sciences.
Worldwide
5-Iodotubercidin
5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC 50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 113939; 5-ITu. CAS No. 24386-93-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 25 mg; 50 mg. Product ID: HY-15424.
CP 316819
CP 316819 has been found to be a glycogen phosphorylase inhibitor and could probably be used in the treatment for glycemic control in type 2 diabetes. Synonyms: CP 316819; CP316819; CP-316819; 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 186392-43-8. Molecular formula: C21H22ClN3O4. Mole weight: 415.87.
CP-316819
A novel glycogen phosphorylase inhibitor; potential treatment for glycemic control in type 2 diabetes. Group: Biochemicals. Alternative Names: 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; GPi 819; CP 316 819. Grades: Highly Purified. CAS No. 186392-43-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP-320626
CP-320626, a carboxamide derivative, is a potent glycogen phosphorylase inhibitor and a possible target for type 2 diabetes therapy. CP-320626 is also a potent inhibitor of human muscle GPa. Synonyms: 5-chloro-N-[(2S)-3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide;CP-320626; CP320626; CP 320626. Grades: >98%. CAS No. 186430-23-9. Molecular formula: C23H23ClFN3O3. Mole weight: 443.90.
CP-91149
CP-91149 is a GP (glycogen phosphorylase) inhibitor. CP-91149 promotes glycogen resynthesis, but not its overaccumulation. CP-91149 has the potential for Type II (insulin-dependent) diabetes study [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186392-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13525.
CP-91149
CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose. Synonyms: CP 91149; CP91149; 5-Chloro-1H-indole-2-carboxylic acid ((1S,2R)-1-benzyl-2-dimethylcarbamoyl-2-hydroxy-ethyl)-amide. Grades: >98%. CAS No. 186392-40-5. Molecular formula: C21H22ClN3O3. Mole weight: 399.87.
GPi 688
GPi 688 is an allosteric glycogen phosphorylase inhibitor that inhibits glucagon-mediated hyperglycemia in the rat. Synonyms: GPi 688; GPi688; GPi-688; 2-Chloro-N-[1-[(2R)-2,3-dihydroxypropyl]-1,2,3,4-tetrahydro-2-oxo-3-quinolinyl]-6H-thieno[2,3-b]pyrrole-5-carboxamide. Grades: ≥99% by HPLC. CAS No. 918902-32-6. Molecular formula: C19H18ClN3O4S. Mole weight: 419.88.
pdGp
pdGp, also known as pyruvate dehydrogenase kinase, is a remarkably efficacious and highly targeted inhibitor of the glycogen phosphorylase (Gp). Synonyms: 2'- Deoxyguanosine- 3', 5'- O- bisphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 16174-59-7. Molecular formula: C10H15N5O10P2. Mole weight: 427.2.
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