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Golvatinib golvatinib (also known as E7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c-Met and VEGFR-2, which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases. c-Met and VEGFR-2 are upregulated in a variety of various tumor cell types and play important roles in tumor cell growth, migration and angiogenesis. Synonyms: E7050; E-7050; E 7050; Golvatinib. CAS No. 928037-13-2. Molecular formula: C33H37F2N7O4. Mole weight: 633.701. BOC Sciences 8
Golvatinib Golvatinib (E-7050) is a potent dual inhibitor of both c-Met and VEGFR2 kinases with IC 50 s of 14 and 16 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-7050. CAS No. 928037-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13068. MedChemExpress MCE
Golvatinib Golvatinib. Group: Biochemicals. Alternative Names: N- [2-Fluoro-4- [ [2- [ [ [4- (4- methyl -1-piperazinyl) -1-piperidinyl] carbonyl] amino] -4-pyridinyl] oxy] phenyl] -N'- (4-fluorophenyl) -1, 1-cyclopropane dicarboxamide; N- [2-Fluoro-4- [ [2- [ [ [4- (4-methylpiperazin-1-yl) piperidin-1-yl] carbonyl] amino] pyridin-4-yl] oxy] phenyl] -N'- (4-fluorophenyl) cyclopropane-1, 1-dicarboxamide. Grades: Highly Purified. CAS No. 928037-13-2. Pack Sizes: 1mg. Molecular Formula: C33H37F2N7O4, Molecular Weight: 633.69. US Biological Life Sciences. USBiological 3
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