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Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: ICI-118630 acetate. CAS No. 145781-92-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13673A.
Goserelin Acetate
Goserelin Acetate. Group: Biochemicals. Alternative Names: 6-[O-(1,1-Dimethylethyl)-D-serine]-1-9-luteinizing Hormone-releasing Factor (swine) 2- (Aminocarbonyl) hydrazide Acetate; Fertilan;D-Ser(But)6Azgly10-gonadorelin. Grades: Highly Purified. CAS No. 145781-92-6. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N??O??; x C?H?O?, Molecular Weight: 1269.41. US Biological Life Sciences.
Worldwide
Goserelin Acetate
Goserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that binds to the GNRH receptor. Synonyms: Fertilan; Zoladex; Glp-His-Trp-Ser-Tyr-[D-Ser(tBu)]-Leu-Arg-Pro-Azagly-NH2. CAS No. 145781-92-6. Molecular formula: C61H88N18O16. Mole weight: 1329.46.
Goserelin EP Impurity C is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-D-Pro-NHNHCONH2; [9-D-proline]goserelin; (9-D-proline)goserelin. Molecular formula: C59H84N18O14. Mole weight: 1269.43.
Goserelin EP Impurity D
Goserelin EP Impurity D is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-NHNHCONH2; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-N'-carbamoyl-L-argininehydrazide; des-9-L-proline-goserelin. Molecular formula: C54H77N17O13. Mole weight: 1172.32.
Goserelin EP Impurity H
Goserelin EP Impurity H is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-D-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHNHCONH2; [1-(5-oxo-D-proline)]goserelin. Molecular formula: C59H84N18O14. Mole weight: 1269.43.
Goserelin EP Impurity I
Goserelin EP Impurity I is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Pro-Pro-NHNHCONH2; endo-8a,8b-di-L-proline-goserelin. Molecular formula: C69H98N20O16. Mole weight: 1463.67.
Goserelin EP Impurity J
Goserelin EP Impurity J is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-Pro-NHNHCONH2; endo-8a-L-proline-goserelin. Molecular formula: C64H91N19O15. Mole weight: 1366.55.
Goserelin EP Impurity K
Goserelin EP Impurity K is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-Ser(Ac)-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHNHCONH2; L-pyroglutamyl-L-histidyl-L-tryptophyl-O-acetyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-N'-carbamoyl-L-prolinehydrazide; [4-(O-acetyl-L-serine)]goserelin. Molecular formula: C61H86N18O15. Mole weight: 1311.47.
Goserelin Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Goserelin System Suitability Mixture
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
4-D-Ser-goserelin
4-D-Ser-goserelin is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-D-Ser(Ac)-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHNHCONH2; L-pyroglutamyl-L-histidyl-L-tryptophyl-O-acetyl-D-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-N'-carbamoyl-L-prolinehydrazide; 4-(acetyl-D-serine)goserelin. Molecular formula: C61H86N18O15. Mole weight: 1311.47.
4-(glycolyl-L-serine)goserelin
4-(glycolyl-L-serine)goserelin is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-D-Ser(Glycolyl)-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHNHCONH2; (6S,9S,12R,15S,18S)-18-((S)-2-((S)-3-(1H-imidazol-5-yl)-2-((S)-5-oxopyrrolidine-2-carboxamido)propanamido)-3-(1H-indol-3-yl)propanamido)-1-amino-12-(tert-butoxymethyl)-6-((S)-2-(2-carbamoylhydrazinecarbonyl)pyrrolidine-1-carbonyl)-15-(4-hydroxybenzyl)-1-imino-9-isobutyl-8,11,14,17-tetraoxo-2,7,10,13,16-pentaazanonadecan-19-yl 2-hydroxyacetate. Molecular formula: C61H86N18O16. Mole weight: 1327.45.
4-(Lactyl-L-serine)goserelin
4-(Lactyl-L-serine)goserelin is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-D-Ser(Lactyl)-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHNHCONH2; (6S,9S,12R,15S,18S)-18-((S)-2-((S)-3-(1H-imidazol-5-yl)-2-((S)-5-oxopyrrolidine-2-carboxamido)propanamido)-3-(1H-indol-3-yl)propanamido)-1-amino-12-(tert-butoxymethyl)-6-((S)-2-(2-carbamoylhydrazinecarbonyl)pyrrolidine-1-carbonyl)-15-(4-hydroxybenzyl)-1-imino-9-isobutyl-8,11,14,17-tetraoxo-2,7,10,13,16-pentaazanonadecan-19-yl 2-hydroxypropanoate. Molecular formula: C62H88N18O16. Mole weight: 1341.47.
6-(des-t-butyl-D-serine)-goserelin
6-(des-t-butyl-D-serine)-goserelin is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-D-Ser-Tyr-D-Ser-Leu-Arg-Pro-NHNHCONH2; (S)-N-((6S,9S,12S,15S,18S,21S,24S)-21-((1H-indol-3-yl)methyl)-1-amino-6-((S)-2-(2-carbamoylhydrazinecarbonyl)pyrrolidine-1-carbonyl)-15-(4-hydroxybenzyl)-12,18-bis(hydroxymethyl)-25-(1H-imidazol-5-yl)-1-imino-9-isobutyl-8,11,14,17,20,23-hexaoxo-2,7,10,13,16,19,22-heptaazapentacosan-24-yl)-5-oxopyrrolidine-2-carboxamide. Molecular formula: C55H76N18O14. Mole weight: 1213.33.
8-(N-Acetylamino-L-arginine)-goserelin
8-(N-Acetylamino-L-arginine)-goserelin is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-D-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro(Ac)-NHNHCONH2; (S)-N-((9S,12S,15R,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-15-(tert-butoxymethyl)-9-((S)-2-(2-carbamoylhydrazinecarbonyl)pyrrolidine-1-carbonyl)-18-(4-hydroxybenzyl)-21-(hydroxymethyl)-28-(1H-imidazol-5-yl)-4-imino-12-isobutyl-2,11,14,17,20,23,26-heptaoxo-3,5,10,13,16,19,22,25-octaazaoctacosan-27-yl)-5-oxopyrrolidine-2-carboxamide. Molecular formula: C61H86N18O15. Mole weight: 1311.47.
(Des-Gly10,D-Ser(tBu)6,Pro-NHNH29)-LHRH
(Des-Gly10,D-Ser(tBu)6,Pro-NHNH29)-LHRH is the impurity E of the Goserelin. Synonyms: Decarbamoylgoserelin; H-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHNH2; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-L-prolinehydrazide; 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-1-9-luteinizing hormone-releasing factor (swine), hydrazide. Grade: 95%. CAS No. 147688-42-4. Molecular formula: C58H83N17O13. Mole weight: 1226.39.
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