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| Product | Description | |
|---|---|---|
| EDA-GppNHp (EDA-GMPPNP) - 5-TAMRA | EDA-GppNHp (EDA-GMPPNP) - 5-TAMRA is a versatile and indispensable fluorescently labeled nucleotide analogue widely employed in the field of biomedical research. It serves as a paramount tool facilitating comprehensive investigations into the intricate interplay between nucleotides and their cognate proteins. Moreover, its applicability spans across diverse experimental setups involving the meticulous scrutiny of nucleotide-binding proteins, the probing of molecular sensors and the elucidation of intricate fluorescence resonance energy transfer (FRET) assays. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-[(β,γ)-imido] triphosphate, labeled with 5-TAMRA, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C38H43N10O18P3(free acid). Mole weight: 1020.73 (free acid). |  |
| EDA-GppNHp (EDA-GMPPNP) - ATTO-488 | EDA-GppNHp (EDA-GMPPNP) - ATTO-488, a fluorescently labeled nucleotide analog, is a vital tool for the study of nucleotide-binding proteins and their interactions. Its utility extends to fluorescence resonance energy transfer (FRET) experiments, where it plays an essential role in monitoring protein conformational changes linked with the actions of nucleotide binding and hydrolysis. EDA-GppNHp has also proven to be useful in the investigation of ATPase and GTPase activities, and in the development of assays for G protein-coupled receptor (GPCR) signaling. Its multifaceted nature offers nuanced insights into complex protein interactions, positioning it as a favorite among researchers invested in these areas. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-[(β,γ)-imido] triphosphate, labeled with ATTO 488, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C38H44N11O23P3S2(free acid). Mole weight: 1179.87 (free acid). | |
| EDA-GppNHp (EDA-GMPPNP) - ATTO-647N | EDA-GppNHp (EDA-GMPPNP) - ATTO-647N is a cutting-edge fluorescent dye conjugate with immense potential application in studying intricate G protein signaling pathways and their dynamic interplay. By effectively illuminating GTP-binding proteins, EDA-GppNHp (EDA-GMPPNP) - ATTO-647N allows for a comprehensive exploration of their involvement in a myriad of afflictions, encompassing the realms of cancer and neurological disorders. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-[(β,γ)-imido] triphosphate, labeled with ATTO 647N, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C13H23N8O14P3- ATTO 647N (free acid). Mole weight: 1236.03 (free acid). | |
| EDA-GppNHp (EDA-GMPPNP) - Biotin | EDA-GppNHp is a derivative compound conjugated with biotin known also as EDA-GMPPNP, widely employed in the biomedical field. Its utilization primarily revolves around deciphering intricate cellular mechanisms, particularly those associated with G protein signaling pathways. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-[(β,γ)-imido] triphosphate - Biotin, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C23H37N10O16P3S (free acid). Mole weight: 834.58 (free acid). | |
| EDA-GppNHp (EDA-GMPPNP) - Cy3 | EDA-GppNHp (EDA-GMPPNP) - Cy3 is a highly versatile and indispensable fluorescent probe, used to unravel the enigmatic mysteries of G proteins and their intricate network of alliances in a myriad of cellular processes. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-[(β,γ)-imido] triphosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C44H59N10O21P3S2(free acid). Mole weight: 1221.05 (free acid). | |
| EDA-GppNHp (EDA-GMPPNP) - Cy5 | EDA-GppNHp (EDA-GMPPNP) - Cy5 is an essential fluorescent dye utilized within the biomedical industry as a protein labeler and detector. Its valuable usage is attributed to its distinctive ability to investigate, study and analyze the activation of G proteins and its associated downstream outcomes in the ailments of cancer and neurological disorders. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-[(β,γ)-imido] triphosphate, labeled with Cy5, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C46H61N10O21P3S2(free acid). Mole weight: 1247.08 (free acid). | |
| 6-Thio-GppNHp | 6-Thio-GppNHp - A Biochemical Product with Revolutionary potential! This product is indispensable in biosciences research and allows scientists to deeply probe the intricacies of G protein signaling pathways. An entirely non-hydrolyzable analog of GTP, 6-Thio-GppNHp has opened up a vast realm of investigations into the effects of G protein activation, intracellular signal transduction, and some of the most enigmatic diseases plaguing humankind - cardiac arrhythmias, immune response, and cancer. Join the path-breaking efforts today with your 6-Thio-GppNHp! Synonyms: (6-Thio-GMPPNP); 6-Thio-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H17N6O12P3S (free acid). Mole weight: 538.25 (free acid). | |
| 8-Bromo-GppNHp | 8-Bromo-GppNHp, a biochemical known for its role in investigating the signaling pathways of G proteins, is gaining notoriety in the field of biomedical research. Primarily, the product is utilized to study G protein-coupled receptors (GPCRs) and their downstream effectors. Beyond that, the research community has found it to be instrumental in studies related to various diseases -- among them cancer, cardiovascular afflictions, and diabetes. As the product continues to prove its worth, it is sure to remain an increasingly important tool for those in the field of biomedical science. Synonyms: (8Br-GppNHp, 8Br-GMPPNP); 8-Bromo-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O13P3Br (free acid). Mole weight: 601.09 (free acid). | |
| 8-Iodo-GppNHp | 8-Iodo-GppNHp, a chemical compound employed in biomedicine to inquire into G-protein signaling pathways, often functions as a non-hydrolyzable GTP analog, providing a means of exploring the activity of G-protein coupled receptors and their associated downstream effectors and target proteins. Its application has examined various afflictions, such as cancer and neurological disorders, advancing our understanding of these conditions. Synonyms: (8I-GppNHp, 8I-GMPPNP); 8-Iodo-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H16N6O13P3I (free acid). Mole weight: 648.09 (free acid). | |
| Guanosine-5'-[(beta,gamma)-imido]triphosphate sodium salt | Guanosine-5'-[(beta,gamma)-imido]triphosphate sodium salt is a vital compound extensively used in biomedical field for its role as a potent activator of G protein-coupled receptors (GPCRs). It facilitates signal transduction pathways in various cellular processes, including neurotransmission, hormone regulation and immune responses. Synonyms: GMPPNP; GppNHp. Molecular formula: C10H17N6O13P3·xNa. Mole weight: 522.20 (free acid). | |
| Guanosine-5'-[(b,gamma)-imido]triphosphate sodium salt | Guanosine-5'-[(b,gamma)-imido]triphosphate sodium salt. Group: Biochemicals. Alternative Names: GMPPNP; GppNHp. Grades: Highly Purified. CAS No. 148892-91-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H17N6O13P3·xNa. US Biological Life Sciences. |  Worldwide |
| Mant-GppNHp | MANT-GppNHp bind to G alpha(I)-proteins with low affinity and are ineffective at activating G alpha. Besides, MANT-GppNHp constitutes a novel class of potent competitive AC inhibitors. Synonyms: (Mant-GMPPNP); 2'/3'-O-(N-Methyl-anthraniloyl)-guanosine-5'-[(β,γ)-imido]triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. CAS No. 148821-01-6. Molecular formula: C18H24N7O14P3(free acid). Mole weight: 655.34 (free acid). | |
| TNP-GppNHp | TNP-GppNHp is an exceedingly sturdy GTP analogue, serving as a catalyst in instigating the activation of GTP-binding proteins, thereby affording an opportunity to scrutinize their intricate signaling cascades. Synonyms: (TNP-GMPPNP); 2',3'-O-Trinitrophenyl-guanosine-5'-[(β,γ)-imido]triphosphate, Triethylammonium salt. Grades: ≥ 90 % by HPLC. Molecular formula: C16H17N9O19P3. Mole weight: 732.28. | |
| GppNHp - Tetralithium salt | The tetrasodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Tetralithium salt; GMPPNHP. Grades: ≥ 95 % by HPLC. CAS No. 64564-03-0. Molecular formula: C10H13N6ONa413P3. Mole weight: 611.13. | |
| GppNHp - Trisodium salt | The trisodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Trisodium salt; GMPPNHP. Grades: ≥ 90 % by HPLC. CAS No. 148892-91-5. Molecular formula: C10H14N6Na3O13P3. Mole weight: 588.14. | |
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