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| Product | Description | |
|---|---|---|
| Guanidine phosphate | Guanidine phosphate. Group: Biochemicals. Grades: Highly Purified. CAS No. 5423-23-4. Pack Sizes: 500g, 1kg, 2kg, 5kg, 10kg. Molecular Formula: CH5N3·H3PO4. US Biological Life Sciences. |  Worldwide |
| E6446 | E6446 is a TLR inhibitor. E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to challenge doses of cytidine-phosphate-guanidine (CpG)-containing DNA, which stimulates TLR9. Group: Inhibitors. Alternative Names: E6446; E 6446; E-6446. CAS No. 1219925-73-1. Molecular formula: C27H35N3O3. Mole weight: 449.6. Appearance: Solid powder. Purity: >98%. IUPACName: 6-(3-Pyrrolidin-1-yl-propoxy)-2-[4-(3-pyrrolidin-1-yl-propoxy)-phenyl]-benzooxazole. Canonical SMILES: C1 (C2=CC=C (OCCCN3CCCC3)C=C2)=NC4=CC=C (OCCCN5CCCC5)C=C4O1. Catalog: ACM1219925731. |  |
| Guanosine 3',5'-cyclic monophosphate | Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Synonyms: D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate; 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-1H-purin-6-one. Grades: ≥ 95%. CAS No. 7665-99-8. Molecular formula: C10H12N5O7P. Mole weight: 345.21. |  |
| Guanosine 5'-monophosphate | Guanosine 5'-monophosphate is a purine ribonucleoside 5'-monophosphate having guanine as the nucleobase. It has a role as a metabolite, a biomarker, an Escherichia coli metabolite and a mouse metabolite. It is a guanosine 5'-phosphate and a purine ribonucleoside 5'-monophosphate. It is a conjugate acid of a guanosine 5'-monophosphate(2-). Guanosine 5'-monophosphate. A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. Synonyms: 5-Guanylic Acid; 5'-GMP; GMP; Guanidine Monophosphate; Guanosine 5'-Phosphate; Guanosine 5'-Phosphoric Acid; Guanosine Monophosphate; Guanylic Acid. Grades: ≥95%. CAS No. 85-32-5. Molecular formula: C10H14N5O8P. Mole weight: 363.22. | |
| Native Aspergillus oryzae Ribonuclease T1 | Ribonuclease T1 (RNase T1) from Aspergillus oryzae is an endoribonuclease that hydrolyzes after G residues. Cleavage occurs between the 3-phosphate group of a guanidine ribonucleotide and 5-hydroxyl of the adjacent nucleotide. The initial product is a 2:3 cyclic phosphate nucleoside that is hydrolyzed to the corresponding 3-nucleoside phosphate. It differs from Pancreatic RNase in that it attacks the guanine sites specifically to yield 3'-GMP and oligonucleotides with a 3'-GMP terminal group. Applications: Ribonuclease t1 (rnase t1) from aspergillus oryzae is used to digest denatured rna prior to sequencing and is used for protein folding studies. Group: Enzymes. Synonyms: Ribonuclease T1; EC 3.1.27.3; g. Enzyme Commission Number: EC 3.1.27.3. CAS No. 9026-12-4. Rnase. Activity: 300,000-600,000 units/mg protein. Storage: -20°C. Form: ammonium sulfate suspension; Suspension in 2.8 M (NH4)2SO4 solution. Source: Aspergillus oryzae. Ribonuclease T1; EC 3.1.27.3; guanyloribonuclease; Aspergillus oryzae ribonuclease; RNase N1; RNase N2; ribonuclease N3; ribonuclease U1; ribonuclease F1; ribonuclease Ch; ribonuclease PP1; ribonuclease SA; RNase F1; ribonuclease C2; binase; RNase Sa; guanyl-specific RNase; RNase G; RNase T1; ribonuclease guaninenucleotido-2'-transferase (cyclizing); ribonuclease N3; ribonuclease N1; 9026-12-4. Cat No: NATE-0658. |  |
| 1-[4-(4-Ethoxyphenyl)thiazol-2-yl]-guanidine Hydrobromide | 1-[4-(4-Ethoxyphenyl)thiazol-2-yl]-guanidine Hydrobromide is related to 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide (M226305), which is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is also used in the preparation of thiazole compounds as myosin light chain phosphatase inhibitors for prostate cancer treatment. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg. Molecular Formula: C12H14N4OS; HBr, Molecular Weight: 262.34. US Biological Life Sciences. | Worldwide |
| 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide | 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is used in the preparation of antiulcer agents, specifically 4-Substituted 2-guanidinothiazoles, which are reversible, competitive, and selective inhibitors of gastric H+,K+-ATPase. 1-(4-(4-Methoxyphenyl)thiazol-2-yl)guanidine Hydrobromide is also used in the preparation of thiazole compounds as myosin light chain phosphatase inhibitors for prostate cancer treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 96996-05-3. Pack Sizes: 500mg, 1g. Molecular Formula: C11H12N4OS; HBr, Molecular Weight: 248.31. US Biological Life Sciences. | Worldwide |
| Adenosine-2',3'-cyclic Phosphate, Dicyclohexyl guanidinium Salt | Adenosine-2',3'-cyclic Phosphate, Dicyclohexyl guanidinium Salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| D-Homoarginine Hemisulfate | D-Homoarginine Hemisulfate is an enantiomer of L-Homoarginine, which is an inhibitor of alkaline phosphatase isoenzymes. Synonyms: N6-(Aminoiminomethyl)-D-lysine Hemisulfate Salt; (R)-2-Amino-6-guanidinohexanoic Acid Hemisulfate Salt. CAS No. 32733-73-6. Molecular formula: C14H34N8O8S. Mole weight: 474.54. | |
| guanidinodeoxy-scyllo-inositol-4-phosphatase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. Group: Enzymes. Synonyms: 1-guanidino-scyllo-inositol 4-phosphatase; 1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase. Enzyme Commission Number: EC 3.1.3.40. CAS No. 9055-28-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3644; guanidinodeoxy-scyllo-inositol-4-phosphatase; EC 3.1.3.40; 9055-28-1; 1-guanidino-scyllo-inositol 4-phosphatase; 1-guanidino-1-deoxy-scyllo-inositol-4-P phosphohydrolase. Cat No: EXWM-3644. | |
| Hh Signaling Antagonist XII, MRT-83 (N- (2-Methyl-5- (3- (3, 4, 5-trimethoxybenzoyl) guanidino) phenyl) - (1, 1-biphenyl) -4-carboxamide) | A cell-permeable acylguanidine compound that is shown to block Hh signaling and act as a potent, reversible and high-affinity Smo (Smoothened) antagonist. Displays 20-60 -fold greater potency than Cyclopamine and competitively inhibits bodipy-cyclopamine binding to Smo (IC50 = 4.6 and 14nM in HEK293-hSMO and HEK293-mSMO cells, respectively). Represses ShhN (N-myristoylated Shh) signaling (IC50=15nM for Gli-dependent luciferase activity in Shh-light2 cells) and SAG- induced C3H10T1/2 cell differentiation (IC50=10nM in an alkaline phosphatase activity assay). Inhibits ShhN (3nM) and SAG (10nM)-mediated proliferation of rat cerebellar granule cell precursors (IC50 ~3 and 6nM, respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| L-Homoarginine hydrochloride | L-Homoarginine is an alkaline phosphatase inhibitor found in blood, cerebrospinal fluid (CSF), and urine, as well as in human intestine and testes tissues. L-Homoarginine also acts as a substrate of CAT1, CAT2A and CAT2B, and CAT1 is a key site with regard to physiological relevance and interactions with related substrates such as L-arginine. Synonyms: NSC 145416; (S)-2-Amino-6-guanidinohexanoic acid hydrochloride. Grades: ≥95%. CAS No. 1483-01-8. Molecular formula: C7H16N4O2·HCl. Mole weight: 224.7. | |
| L-Homoarginine hydrochloride | L-Homoarginine may be used to create non-natural proteins for studies of post-translational protein modifications. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements. L-Homoarginine is used to study the mechanisms of nitric oxide production by cells via nitric oxide synthase(s). L-Homoarginine is used as a selective mammalian alkaline phosphatase isoenzyme inhibitor. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Group: Amino acids. Alternative Names: (S)-2-Amino-6-guanidinohexanoic acid hydrochloride. CAS No. 1483-01-8. Molecular formula: H2NC(=NH)NH(CH2)4CH(NH2)CO2H · HCl. Mole weight: 224.69. Canonical SMILES: Cl[H].N[C@@H](CCCCNC(N)=N)C(O)=O. ECNumber: 216-045-6. Catalog: ACM1483018-1. | |
| L-Homoarginine, Hydrochloride (2-Amino-6-guanidino-hexanoic Acid, HCl) | An inhibitor of alkaline phosphatase isoenzymes. Group: Biochemicals. Alternative Names: 2-Amino-6-guanidino-hexanoic Acid, HCl. Grades: Highly Purified. CAS No. 1483-01-8. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
| scyllo-inosamine-4-phosphate amidinotransferase | 1D-1-Guanidino-3-amino-1,3-dideoxy-scyllo-inositol 6-phosphate, streptamine phosphate and 2-deoxystreptamine phosphate can also act as acceptors; canavanine can act as donor. Group: Enzymes. Synonyms: L-arginine:inosamine-P-amidinotransferase; inosamine-P amidinotransferase; L-arginine:inosamine phosphate amidinotransferase; inosamine-phosphate amidinotransferase. Enzyme Commission Number: EC 2.1.4.2. CAS No. 52227-63-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2023; scyllo-inosamine-4-phosphate amidinotransferase; EC 2.1.4.2; 52227-63-1; L-arginine:inosamine-P-amidinotransferase; inosamine-P amidinotransferase; L-arginine:inosamine phosphate amidinotransferase; inosamine-phosphate amidinotransferase. Cat No: EXWM-2023. | |
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