guanosine 3',5'-cyclic monophosphate sodium salt suppliers USA
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Guanosine 3?,5?-cyclic Monophosphate, Sodium Salt - CAS 40732-48-7
Important intracellular second messenger implicated in the action of nitric oxide in many cell types. Group: Fluorescence/luminescence spectroscopy.
2',3'-cGAMP sodium salt
2',3'-cGAMP sodium is an endogenous cGAMP in mammalian cells. 2',3'-cGAMP sodium binds to STING with a high affinity and is a potent inducer of interferon-&beta. 2',3'-cGAMP is an effective adjuvant that boosts the production of antigen-specific antibodies and T cell responses in mice. Synonyms: Cyclic [G(2',5')pA(3',5')p] sodium; cyclic GMP-AMP sodium; 2',3'-cyclic GMP-AMP sodium; 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt. Grades: 95%. CAS No. 2734858-36-5. Molecular formula: C20H22N10Na2O13P2. Mole weight: 718.38.
2',3'-cGMP sodium
2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Guanosine 2',3'-cyclic monophosphate sodium salt. CAS No. 15718-49-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N8245.
8-[(6-Amino)hexyl]-amino-cGMP
8-[(6-Amino)hexyl]-amino-cGMP, a derivative of cyclic guanosine monophosphate (cGMP), displays potential for therapeutic use in diseases like hypertension and erectile dysfunction. This analogue's efficacy lies within its ability to enhance smooth muscle relaxation and trigger vasodilation. With the potential to alleviate the symptoms of these ailments, 8-[(6-Amino)hexyl]-amino-cGMP offers a promising avenue for further study and development. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P (free acid). Mole weight: 459.39 (free acid).
8-NBD-cGMP
8-NBD-cGMP is a fluorescent activator of both isozymes I α and I β of cGMP-dependent protein kinase. 8-NBD-cGMP fluoresces strongly in hydrophobic environments. Synonyms: 8- (2-[7-Nitro-4-benzofurazanyl]aminoethylthio) guanosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 115993-88-9. Molecular formula: C18H17N9NaO10PS. Mole weight: 605.41.
cGMP
cGMP, a cyclic guanosine monophosphate, possesses an essential role in governing numerous physiological processes. Significantly employed as a pharmacological focal point in the biomedical realm to combat the likes of hypertension and pulmonary arterial hypertension, its potency is immense. Furthermore, it is intricately involved in the signal transduction pathways of selected neurotransmitters and hormones. Synonyms: Guanosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H12N5O7P (free acid). Mole weight: 345.20 (free acid).
Guanosine-3',5'-cyclic monophosphorothioate,rp-isomer sodium salt
Guanosine-3',5'-cyclic monophosphorothioate,rp-isomer sodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 8-PIP-cAMP, 31357-06-9, P0872_SIGMA, CTK8F7436, AG-F-04393, 8-Piperidinoadenosine 3,5-monophosphate sodium salt, 8-Piperidinoadenosine 3 inverted exclamation marka,5 inverted exclamation marka-monophosphate sodium salt, Adenosine,8-piperidino-, cyclic 3,5-(hydrogen phosphate) (8CI);4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.; 8-Piperidino-cyclicAMP; 8-Piperidinoadenosine 3,5-monophosphate; Cyclic 8-piperidino-3,5-AMP. Product Category: Heterocyclic Organic Compound. Appearance: white solid. CAS No. 31357-06-9. Molecular formula: C15H20N6O6P.Na. Mole weight: 434.32. Purity: 0.96. IUPACName: sodium;(4aR,6R,7R,7aS)-6-(6-amino-8-piperidin-1-ylpurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol. Canonical SMILES: C1CCN(CC1)C2=NC3=C(N2C4C(C5C(O4)COP(=O)(O5)[O-])O)N=CN=C3N.[Na+]. Product ID: ACM31357069. Alfa Chemistry ISO 9001:2015 Certified.
Guanosine,N-(6-aminohexyl)-,cyclic 3',5'-(hydrogen phosphate)(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-AH-CGMP SODIUM SALT;N2-(6-AMINOHEXYL) GUANOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;n2-(6-aminohexyl)guanosine-3',5'-cyclicmonophosphate(2-ah-cgmp). Product Category: Heterocyclic Organic Compound. Appearance: Crystallized or lyophilized solid. CAS No. 205368-58-7. Molecular formula: C16H25N6O7P. Mole weight: 466.36. Purity: 0.96. IUPACName: sodium;9-[(4aR,6R,7R,7aS)-7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-(6-aminohexylamino)-3H-purin-6-one. Canonical SMILES: C1C2C(C(C(O2)N3C=NC4=C3NC(=NC4=O)NCCCCCCN)O)OP(=O)(O1)[O-].[Na+]. Product ID: ACM205368587. Alfa Chemistry ISO 9001:2015 Certified.
2'-[DY505-05]-AHC-cGMP
2'-[DY505-05]-AHC-cGMP is a fluorescent cGMP analogue (λexc505 nm, λem530 nm) that can be used for phosphodiesterase studies. Synonyms: 2'- O- (6- [DY-505-05]- aminohexylcarbamoyl))guanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H37N9O12P · Na. Mole weight: 865.7.
2'-TAMRA-AEC-cGMP
2'-TAMRA-AEC-cGMP is a fluorescent cGMP analogue (λexc555 nm, λem580 nm) that can be used for phosphodiesterase studies. Synonyms: 2'- O- (2- [Tetramethylrhodaminyl] aminoethylcarbamoyl) guanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H37N9O12P · Na. Mole weight: 865.7.
2'-TAMRA-AHC-cGMP
2'-TAMRA-AHC-cGMP is a fluorescent cGMP analogue (λexc555 nm, λem580 nm) that can be used for phosphodiesterase studies. Synonyms: 2'- O- (6- [Tetramethylrhodaminyl] aminohexylcarbamoyl) guanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C42H45N9O12P · Na. Mole weight: 921.8.
8-pCPT-cGMP
8-pCPT-cGMP is a selective activator of cGMP-dependent protein kinase type I α and type II, as well as of cGMP-gated ion channels. It has higher membrane permeability and stability towards many phosphodiesterases. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 51239-26-0. Molecular formula: C16H14ClN5O7PS · Na. Mole weight: 509.8.
c[3'-AHC-G(2',5')pA(3',5')p]
c[3'-AHC-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. Synonyms: Cyclic (3'- O- (6- aminohexylcarbamoyl)guanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C27H38N12O14P2 (free acid). Mole weight: 816.6 (free acid).
c[3'-Fluo-AHC-G(2',5')pA(3',5')p]
c[3'-Fluo-AHC-G(2',5')pA(3',5')p] is a fluorescent analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator. Synonyms: Cyclic (3'-O- (6-[fluoresceinyl]aminohexylcarbamoyl) guanosine- (2'?5') -monophosphate-adenosine- (3'?5') -monophosphate) , sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C48H48N12O20P2. Mole weight: 1174.9.
c[8-AET-G(2',5')pA(3',5')p]
c[8-AET-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which is used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. c[G(2',5')pA(3',5')p] is the metazoan second messenger produced by cGAMP synthase (cGAS), the mammalian intrinsic immune DNA sensor. Synonyms: Cyclic (8- (2- aminoethylthio)guanosine- (2' -≥ 5')- monophosphate- adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C22H29N11O13P2S (free acid). Mole weight: 749.6 (free acid).
c[8-Fluo-AET-G(2',5')pA(3',5')p]
c[8-Fluo-AET-G(2',5')pA(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger. It is a potential tracer in immunoassays and commonly used for affinity chromatography and pull-down assays. Synonyms: Cyclic(8-(2-[fluoresceinyl]aminoethylthio)-guanosine-(2'?5')-monophosphate-adenosine-(3'?5')-monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C43H39N11O19P2S (free acid). Mole weight: 1107.9 (free acid).
c[G(2',5')p-2'-AHC-A(3',5')p]
c[G(2',5')p-2'-AHC-A(3',5')p] is an analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator, which can be used as a ligand for affinity chromatography or for coupling of labelling structures such as fluorophores. Synonyms: Cyclic (guanosine- (2' -≥ 5')- monophosphate- 2'- O- (6- aminohexylcarbamoyl)adenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C27H38N12O14P2 (free acid). Mole weight: 816.6 (free acid).
c[G(2',5')p-2'-dA(3',5')p]
c[G(2',5')p-2'-dA(3',5')p] is a 2'-deoxy analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING stimulator, which can be used for studying ligand-receptor interactions. Synonyms: Cyclic (guanosine- (2' -≥ 5')- monophosphate- 2'- deoxyadenosine- (3' -≥ 5')- monophosphate), sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C20H24N10O12P2 (free acid). Mole weight: 658.4 (free acid).
c[G(2',5')p-2'-Fluo-AHC-A(3',5')p]
c[G(2',5')p-2'-Fluo-AHC-A(3',5')p] is a fluorescent analogue of c[G(2',5')pA(3',5')p], the metazoan cyclic dinucleotide second messenger and STING activator. Synonyms: Cyclic (guanosine- (2'?5') -monophosphate-2'-O- (6-[fluoresceinyl]aminohexylcarbamoyl) adenosine- (3'?5') -monophosphate) , sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C48H48N12O20P2. Mole weight: 1174.9.
Cyclic GMP sodium salt
Cyclic GMP or cGMP is a second messenger and it is biosynthesized from GTP by guanylate cyclases. Nitric oxide and natriuretic peptides arw activators of guanylate cyclases. cGMP activates protein kinase G (PKG) and modulates ion channel conductance, with signaling affecting diverse processes including smooth muscle relaxation and proliferation, phototransduction, and energy homeostasis. Synonyms: cGMP; Cyclic guanosine monophosphate; Guanosine 3'5'-cyclic monophosphate; Monosodium-GMP. Grades: ≥98%. CAS No. 40732-48-7. Molecular formula: C10H11N5O7P·Na. Mole weight: 367.2.
DB-cGMP
DB-cGMP, an exceedingly compelling analogue of cyclic guanosine monophosphate (cGMP), a pivotal secondary messenger in myriad biological processes, serves as an invaluable tool in biomedical research. With a primary focus on unraveling the intricate role of cGMP in signal transduction pathways, cellular proliferation, and apoptosis, it facilitates the understanding of diseases stemming from aberrant cGMP signaling. Synonyms: N2, 2'- O- Dibutyrylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 51116-00-8. Molecular formula: C18H23N5O9P · Na. Mole weight: 507.4.
Guanosine-2'(3')-monophosphate disodium salt
Guanosine-2'(3')-monophosphate disodium salt, a remarkable biomedicine product, emerges as a potent weapon in combating a myriad of multifarious diseases. Its unrivaled prowess as a precursor to cyclic guanosine monophosphate, an integral second messenger orchestrating intricate cellular signaling pathways, renders it indispensable. Synonyms: Guanylic acid disodium salt; Guanosine 2'-3'-monophosphate disodium salt mixed Isomers; 2'-Guanylic acid, disodium salt; (2R,3R,4R,5R)-2-(2-amino-6-hydroxypurin-9-yl)-4-hydroxy-5-(hydroxymethyl)oxola n-3-yl dihydrogen phosphate, sodium salt, sodium salt. Grades: 98%. CAS No. 70347-42-1. Molecular formula: C10H12N5O8PNa2. Mole weight: 407.18.
Guanosine 3?,5?-cyclic Monophosphorothioate, ?-Phenyl-1,N²-etheno-8-bromo-, Rp-Isomer, Sodium Salt - CAS 172806-20-1
A metabolically-stable, competitive inhibitor of protein kinase G types 1? and 1? (Ki = 30 nM). Group: Fluorescence/luminescence spectroscopy.
Guanosine,8-bromo-,cyclic 3',5'-[hydrogen(R)-phosphorothioate](9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: RP-8-BR-CGMPS;RP-8-BR-CGMPS, NA;RP-8-BR-CGMPS SODIUM SALT;RP-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOTE, SODIUM SALT;GUANOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-BROMO-, RP-ISOMER, SODIUM SALT;8-BROMOGUANOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP. Product Category: Heterocyclic Organic Compound. Appearance: White lyophilized powder. CAS No. 150418-07-8. Molecular formula: C10H11BrN5O6PS. Mole weight: 440.167. Density: 2.53 g/cm³. Product ID: ACM150418078. Alfa Chemistry ISO 9001:2015 Certified.
Rp-8-pCPT-cGMPS
Rp-8-pCPT-cGMPS is a selective inhibitor of protein kinase G I a, I ß and especially of type II, which stimulates retinal cGMP channels and discriminates between kinase and channel effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to Rp-cGMPS or Rp-8-Br-cGMPS, it exhibits more lipophilic and membrane-permeant properties. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 153660-04-9. Molecular formula: C16H14ClN5O6PS2 · Na. Mole weight: 525.9.
Rp-cGMPS
Rp-cGMPS is an inhibitor of protein kinase G Iα with an antagonistic effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Both membrane permeability and kinase specificity of Rp-cGMPS are low. Synonyms: Guanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 86562-09-6. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3.
Sp-8-pCPT-cGMPS
Sp-8-pCPT-cGMPS is a stimulator of protein kinase G type I α and type II with superior membrane permeability and stability. Uses: Enzyme inhibitors. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 160385-87-5. Molecular formula: C16H14ClN5O6PS2 · Na. Mole weight: 525.9.
Sp-cGMPS
Sp-cGMPS is a resistant stimulator of cGMP-dependent protein kinases. Synonyms: Guanosine- 3', 5'- cyclic monophosphorothioate, Sp- isomer, sodium salt. Grades: ≥ 99% by HPLC. CAS No. 86562-10-9. Molecular formula: C10H11N5O6PS · Na. Mole weight: 383.3.
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