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2'-Deoxyguanosine-5'-diphosphate is a fundamental biomedical entity enabling DNA research and development, exercising a pivotal function in the intricate process of DNA replication and repair. Synonyms: dGDP; Deoxyguanosine 5'-diphosphate; deoxyguanosine diphosphate; 2'-deoxyguanosine 5'-(trihydrogen diphosphate); 2'-Deoxy-GDP; Guanosine, 2'-deoxy-, 5'-(trihydrogen pyrophosphate); Guanosine, 2'-deoxy-, 5'-pyrophosphate. Grade: ≥98% by HPLC. CAS No. 3493-9-2. Molecular formula: C10H15N5O10P2. Mole weight: 427.20.
2'-Deoxyguanosine-5'-diphosphate disodium salt
2'-Deoxyguanosine-5'-diphosphate disodium salt, a biochemical reagent employed in the investigation of DNA synthesis and repair, as well as in the formation of DNA adducts, and DNA sequencing templates creation, holds potential as a therapeutic agent in the fight against pathologies such as HIV. Synonyms: Guanosine 5'-(trihydrogen diphosphate), 2'-deoxy-, disodium salt; 2'-Deoxyguanosine 5'-diphosphoric acid α,β-disodium salt; Disodium 2'-deoxyguanosine 5'-diphoshate; Disodium 2'-deoxy-5'-O-{[(hydroxyphosphinato)oxy]phosphinato}guanosine. Grade: ≥95% by HPLC. CAS No. 78101-74-3. Molecular formula: C10H13N5O10P2.2Na. Mole weight: 471.16.
6-Thioguanosine-5'-O-diphosphate(6-t-gdp)
6-Thioguanosine-5'-O-diphosphate(6-t-gdp). Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thiogdp, p(S)pg, 6-thioguanosine 5-diphosphate, Guanosine 5-(beta-thio)diphosphate, CID3035439, Guanosine 5-(trihydrogen diphosphate), 6-thio-, 9beta-Ribofuranosyl-2-amino-6-mercaptopurine 5-diphosphate, 16541-19-8. Product Category: Heterocyclic Organic Compound. CAS No. 16541-19-8. Molecular formula: C10H15N5O10P2S. Mole weight: 459.266122 [g/mol]. Purity: 0.96. IUPACName: [(2R,3S,4R)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate. Product ID: ACM16541198. Alfa Chemistry ISO 9001:2015 Certified. Categories: 6-thioguanosine diphosphate.
7-Methylguanosine 5'-diphosphate sodium
7-Methylguanosine 5'-diphosphate sodium is a pivotal biomolecular recompound assuming a critical function as a substrate stimulus for catalytic enzymes engaged in RNA bioresearch and development. Simultaneously, it exerts influential control over intricate cellular mechanisms encompassing gene expression modulation and cell signaling orchestration. Synonyms: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-, inner salt, compd. with sodium salt(1:1); m7GDP sodium salt; 7-Methyl-guanosine-5'-diphosphate sodium salt; 7-Methyl-GDP sodium salt; 7-Methylguanosine diphosphate sodium salt; N7-Methyl-GDP sodium salt; 7-Methylguanosine 5'-diphosphate monosodium salt; 1H-Purinium, 2-amino-6,9-dihydro-9-[5-O-[hydroxy(phosphonooxy)phosphinyl]-β-D-ribofuranosyl]-7-methyl-6-oxo-, inner salt, monosodium salt. Grade: ≥95% by HPLC. CAS No. 104809-16-7. Molecular formula: C11H16N5NaO11P2. Mole weight: 479.21.
7-Methylguanosine 5'-diphosphate TEA salt
m7GDP TEA salt, a derivative nucleoside, bears significant implications in the study of RNA capping. Notably, it partakes in the capping of mRNA during transcription and substantiates an inhibitory effect against viral infections, such as Flavivirus, rendering it an invaluable research asset. Synonyms: Guanosine 5'-(trihydrogen diphosphate), 7-methyl-, inner salt, compd. with N,N-diethylethanamine (1:x); m7GDP TEA salt; 7-Methyl-guanosine-5'-diphosphate TEA salt; 7-Methyl-GDP TEA salt; 7-Methylguanosine diphosphate TEA salt; N7-Methyl-GDP TEA salt. Grade: ≥95% by HPLC. CAS No. 240137-50-2. Molecular formula: C11H17N5O11P2.xC6H15N. Mole weight: 457.23 (free acid).
a,b-Methyleneguanosine 5'-diphosphate sodium salt
a,b-Methyleneguanosine 5'-diphosphate sodium salt, as a fundamental chemical compound, finds wide applications in the biomedical sector due to its therapeutic potential across diverse diseases. With its significant contribution to vital cellular mechanisms and signal transduction pathways, this compound essentially facilitates the synthesis and metabolism of guanosine triphosphate, a pivotal molecule implicated in numerous biological processes. Synonyms: GMPCP; GPCP. Molecular formula: C11H17N5O10P2·xNa. Mole weight: 441.23 (free acid).
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
This enzyme belongs to the family of hydrolases, specifically those acting on diphosphoric monoester bonds. This enzyme participates in purine metabolism. Group: Enzymes. Synonyms: guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase; PpGpp-3'-pyrophosphohydrolase; PpGpp phosphohydrolase. Enzyme Commission Number: EC 3.1.7.2. CAS No. 70457-12-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3763; guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; EC 3.1.7.2; 70457-12-4; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphatase; PpGpp-3'-pyrophosphohydrolase; PpGpp phosphohydrolase. Cat No: EXWM-3763.
Guanosine 3',5'-diphosphate tetralithium salt. Group: Biochemicals. Alternative Names: 3',5'-Diphosphoguanosine tetralithium salt. Grades: Highly Purified. CAS No. 32452-17-8,55612-39-0,3237-37-4. Pack Sizes: 50mg. Molecular Formula: C10H11Li4N5O11P2. US Biological Life Sciences.
Worldwide
Guanosine 3',5'-Diphosphate Tetralithium Salt
Guanosine 3',5'-Diphosphate Tetralithium Salt is a drug transporter on the arachnoid barrier cells that contribute to blood-cerebrospinal fluid barrier. Synonyms: Guanosine 3',5'-Bis(dihydrogen Phosphate) Tetralithium Salt; 3',5'-Diphosphoguanosine Tetralithium Salt. CAS No. 55612-39-0. Molecular formula: C10H11Li4N5O11P2. Mole weight: 466.93.
Guanosine 3'-diphosphate 5'-triphosphate
Guanosine 3'-diphosphate 5'-triphosphate is a pivotal molecule entwined in signal transduction and protein synthesis, emerging as an indispensable compound. It exert its prowess as an enthusiastic bestower of energy during translation, while adroitly orchestrating the activity of G-proteins. It assumes a role in unraveling the enigmatic dynamics of enzyme kinetics, nucleotide metabolism and the meticulous dissection of ailments synonymous to G-protein signaling cascades. Synonyms: Guanosine-3',5'-pentaphosphate; Guanosine pentaphosphate; pppGpp; Guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate); ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydroxy-3-((hydroxy(phosphonooxy)phosphoryl)oxy)tetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 5'-Triphosphoguanosine 3'-diphosphate. Grade: ≥95%. CAS No. 38918-96-6. Molecular formula: C10H18N5O20P5. Mole weight: 683.14.
Guanosine 3'-(trihydrogen diphosphate), 5'-(trihydrogen diphosphate) is an imperative molecule aiding in the study against cancer, viral infections and neurological disorders. Synonyms: ppGpp; Guanosine 3',5'-bisdiphosphate. Grade: 95%. CAS No. 32452-17-8. Molecular formula: C10H17N5O17P4. Mole weight: 603.16.
Guanosine 5'-diphosphate
Guanosine 5'-diphosphate (GDP) is a nucleotide composed of the base guanine, the sugar ribose, and two phosphate groups. It plays a crucial role in cellular processes, acting as a substrate in signal transduction pathways and as a building block in RNA synthesis. GDP is also involved in energy transfer and regulatory mechanisms within cells, particularly in GTP-binding proteins and metabolic pathways. Synonyms: GDP; ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; Guanosine diphosphate; 2-amino-9-{5-O-[hydroxy(phosphonooxy)phosphoryl]-β-D-ribofuranosyl}-9H-purin-6-ol; Guanosine 5'-(trihydrogen diphosphate). Grade: ≥95% by HPLC. CAS No. 146-91-8. Molecular formula: C10H15N5O11P2. Mole weight: 443.20.
Guanosine 5'-diphosphate disodium salt
Guanosine 5'-diphosphate disodium salt is an imperative biomolecule esteemed in the biomedical sector, exhibiting noteworthy involvement in cellular signaling and serves as a substrate for diverse nucleic acid metabolism-encompassing enzymes. Its significance is exemplified through extensive employment in research and manufacturing, enabling comprehensive exploration of G-protein coupled receptors, protein synthesis and drug discovery-related signaling pathways, as well as disease research. Synonyms: GDP-Na2; Disodium 5'-O-{[(hydroxyphosphinato)oxy]phosphinato}guanosine; GDP.Na2; 5'-GDP-Na2; Guanosine 5'-(trihydrogen diphosphate), disodium salt; Guanosinepyrophosphate, disodium salt; Disodium guanosine 5'-diphosphate; Guanosine-5'-diphosphoric acid disodium salt. Grade: 98%. CAS No. 7415-69-2. Molecular formula: C10H13N5Na2O11P2. Mole weight: 487.16.
Guanosine 5'-diphosphate disodium salt
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K + channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)- ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: GDP disodium salt. CAS No. 7415-69-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-113066A.
Guanosine 5'-Diphosphate Disodium Salt
Pyruvate kinase substrate. Guanosine-5'-diphosphate disodium salt is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors. It is also used to study cell signaling processes mediate by guanine nucleotide exchange factors. Group: Biochemicals. Alternative Names: 5'-GDP·2Na; Guanosine 5'-diphosphoric acid disodium salt. Grades: Highly Purified. CAS No. 7415-69-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C10H13N5O11P2·2Na, Molecular Weight: 487.17. US Biological Life Sciences.
Worldwide
Guanosine-5'-diphosphate disodium salt (GDP)
100mg Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C10H13N5Na2O11P2. CAS No. 7415-69-2. Prepack ID 78355753-100mg. Molecular Weight 487.16. See USA prepack pricing.
Guanosine-5'-diphosphate disodium salt ≥95% (HPLC)
Guanosine-5'-diphosphate disodium salt ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Guanosine 5?-diphosphate sodium salt
Type I, ?96% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Guanosine 5'-diphosphate sodium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 43139-22-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C10H15N5O11P2·xNa. US Biological Life Sciences.
Worldwide
Guanosine 5'-Diphosphate Triammonium Salt
Guanosine 5'-Diphosphate Triammonium Salt is an intermediate in the eukaryotic messenger ribonucleic acid cap binding protein synthesis. Synonyms: Guanosine 5'-(Trihydrogen Diphosphate), Triammonium Salt; Triammonium Guanosine 5'-Diphosphate. CAS No. 79441-34-2. Molecular formula: C10H16N6O11P2. Mole weight: 458.22.
Guanosine 5?-diphosphate tris salt from Saccharomyces cerevisiae
Type VI, ?92.5%. Group: Fluorescence/luminescence spectroscopy.
Guanosine-5'-O-(2-thiodiphosphate)
GDP-βS is guanosine 5'-O-(2-thiodiphosphate), a modified form of guanosine diphosphate (GDP) where the oxygen in the β-phosphate position is replaced by a sulfur atom. It is commonly used as a non-hydrolyzable analog of GDP in biochemical studies to investigate GTPase activity, signal transduction pathways, and molecular mechanisms involving GTP-binding proteins (G proteins). Synonyms: 5'-Guanylic acid, anhydride with phosphorothioic acid (1:1); 5'-Guanylic acid, monoanhydride with phosphorothioic acid; GDP-βS; Guanosine 5'-(β-thiodiphosphate); Guanosine 5'-O-(2-thiodiphosphate); Guanosine 5'-O-(β-thiodiphosphate); Guanyl-5'-yl thiophosphate. Grade: ≥90% by HPLC. CAS No. 71376-97-1. Molecular formula: C10H15N5O10P2S. Mole weight: 459.27.
Guanosine 5'-O-(2-Thiodiphosphate) Trilithium Salt
Guanosine 5'-O-(2-Thiodiphosphate) Trilithium Salt is a GDP analog which could inhibits G-protein activation. Synonyms: 5'-Guanylic acid, monoanhydride with phosphorothioic acid, trilithium salt; EINECS 308-328-9; Guanosine 5'-O-(2-thiodiphosphate) trilithium salt; trilithium; [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dioxidophosphinothioyl phosphate; Guanosine 5'-[beta-thio]diphosphate trilithium salt; GDP-beta-S-Li3; GDPbetaS trilithium salt; Guanosine 5'-O-(2-Thiodiphosphate), Trilithium Salt; MFCD00057735; Guanosine 5-O-(2-thiodiphosphate)trilithium salt; Guanosine,5'-esterwith thiodiphosphoric acid([(ho)2p(o)]2s)(9ci); Guanosine 5'-[beta-thio]diphosphate trilithium salt, >=85% (HPLC), powder. CAS No. 97952-36-8. Molecular formula: C10H12Li3N5O10P2S. Mole weight: 477.07.
Also hydrolyses other guanosine 5'-triphosphate derivatives with at least one unsubstituted phosphate group on the 3'-position, but not GTP, ATP or adenosine 5'-triphosphate 3'-diphosphate. Group: Enzymes. Synonyms: pppGpp 5'-phosphohydrolase; guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase; guanosine pentaphosphatase; guanosine pentaphosphate phosphatase; guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase; guanosine pentaphosphate phosphohydrolase. Enzyme Commission Number: EC 3.6.1.40. CAS No. 85130-44-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4617; guanosine-5'-triphosphate,3'-diphosphate phosphatase; EC 3.6.1.40; 85130-44-5; pppGpp 5'-phosphohydrolase; guanosine 5'-triphosphate-3'-diphosphate 5'-phosphohydrolase; guanosine pentaphosphatase; guanosine pentaphosphate phosphatase; guanosine 5'-triphosphate 3'-diphosphate 5'-phosphatase; guanosine pentaphosphate phosphohydrolase. Cat No: EXWM-4617.
2',3'-O-(Methoxymethylene)-6-thio-guanosine
2',3'-O-(Methoxymethylene)-6-thio-guanosine is an intermediate in the synthesis of Thioguanosine Diphosphate Ammonium Salt (T350775). Thioguanosine Diphosphate is a thiopurine metabolite found in red blood cells of patients undergoing long-term azatioprine therapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 1213237-01-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C12H15N5O5S. US Biological Life Sciences.
Worldwide
2',3'-O-(Methoxymethylene)-6-thio-guanosine
2',3'-O-(Methoxymethylene)-6-thio-guanosine is an intermediate in the synthesis of Thioguanosine Diphosphate Ammonium Salt. Thioguanosine Diphosphate is a thiopurine metabolite found in red blood cells of patients undergoing long-term azatioprine therapy. Synonyms: 2-Amino-9-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2-methoxytetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-1H-purine-6(9H)-thione. CAS No. 1213237-01-4. Molecular formula: C12H15N5O5S. Mole weight: 341.34.
5'-Phosphoguanylyl-(3'->5')-guanosine
5'-Phosphoguanylyl-(3'->5')-guanosine. Group: Biochemicals. Alternative Names: pGpG; P1-(5-Guanosyl)-P2-(5-guanosyl)-(3->5)-diphosphate sodium salt. Grades: Highly Purified. CAS No. 33008-99-0. Pack Sizes: 250ug. Molecular Formula: C20H26N10O15P2·xNa. US Biological Life Sciences.
Worldwide
6-Thio-GDP
6-Thio-GDP, a significant compound, plays a pivotal role in the biomedical realm, primarily owing to its immense potential for treating cancer and autoimmune disorders. The compound's exceptional structure lends itself to exerting compelling inhibitory influences on distinct signaling pathways, thus offering substantial prospects as a targeted therapy contender. Synonyms: 6-Thio-guanosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 16541-19-8. Molecular formula: C10H15N5O10P2S (free acid). Mole weight: 459.26 (free acid).
6-Thio-GpCp
6-Thio-GpCp, a compound that exhibits inhibitory activities against viral replication as well as DNA synthesis in cancerous cells, is a compound with immense potential in the fight against viral infections and specific types of cancer. It has demonstrated compelling data in preclinical trials and is currently under development for further clinical investigation. Synonyms: (6-Thio-GMPCP); 6-Thio-guanosine-5'-[(α,β)-methyleno]diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C11H17N5O9P2S (free acid). Mole weight: 457.29 (free acid).
8-Bromo-GDP
8-Bromo-GDP is an exemplary and formidable analogue of guanosine diphosphate (GDP), facilitating the research of GTP-binding proteins and the mechanisms of signaling pathways, protein enmeshment and GTPase activity. Synonyms: (8Br-GDP); 8-Bromo-guanosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H14N5O11P2Br (free acid). Mole weight: 522.09 (free acid).
8-Iodo-GDP
8-Iodo-GDP, a nucleotide analog, facilitates in the study of molecular mechanisms of signal transduction with promising applications in cancer therapies. Along with its ability to inhibit assembly and disassembly of the microtubule network,it has also garnered significant attention for its potential in treating neurological diseases, including Alzheimer's and Huntington's. Synonyms: (8I-GDP); 8-Iodo-guanosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H14N5O11P2I (free acid). Mole weight: 569.10 (free acid).
adenylosuccinate synthase
In molecular biology, Adenylosuccinate synthase (EC 6.3.4.4.) is an enzyme that plays an important role in purine biosynthesis, by catalysing the guanosine triphosphate (GTP)-dependent conversion of inosine monophosphate (IMP) and aspartic acid to guanosine diphosphate (GDP), phosphate and N(6)-(1,2-dicarboxyethyl)-AMP. Group: Enzymes. Synonyms: IMP-aspartate ligase; adenylosuccinate synthetase; succinoadenylic kinosynthetase; succino-AMP synthetase. Enzyme Commission Number: EC 6.3.4.4. CAS No. 9023-57-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5796; adenylosuccinate synthase; EC 6.3.4.4; 9023-57-8; IMP-aspartate ligase; adenylosuccinate synthetase; succinoadenylic kinosynthetase; succino-AMP synthetase. Cat No: EXWM-5796.
α-1,3/4-fucosyltransferase from Helicobacter mustelae, Recombinant
A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate.
α-1,3/4-fucosyltransferase from Helicobacter mustelae, Recombinant
A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. Group: Enzymes. Synonyms: Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Enzyme Commission Number: EC 2.4.1.65. CAS No. 37277-69-3. Purity: min 95% by SDS-PAGE. α-fucosyltransferase. Source: E. coli. Species: Helicobacter mustelae. Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Cat No: NATE-1484.
α-1,3-fucosyltransferase from Helicobacter pylori, Recombinant
A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate.
α-1,3-fucosyltransferase from Helicobacter pylori, Recombinant
A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. Group: Enzymes. Synonyms: glycoprotein 3-alpha-L-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase; EC 2.4.1.214; Glycoprotein 3-alpha-L-fucosyltransferase. Enzyme Commission Number: EC 2.4.1.214. CAS No. 68247-53-0. Purity: min 95% by SDS-PAGE. α-fucosyltransferase. Source: E. coli. Species: Helicobacter pylori. glycoprotein 3-alpha-L-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc alpha 1,3-fucosyltransferase; EC 2.4.1.214; Glycoprotein 3-alpha-L-fucosyltransferase. Cat No: NATE-1483.
Ant-m7GDP
Ant-m7GDP is an exceptional pharmacological compound characterized by its profound capacity to combat viral infections. This awe-inspiring compound exhibits an unparalleled proclivity for selectively targeting and disrupting the intricate guanosine triphosphate cap structures, thereby impeding the vital process of viral mRNA capping. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-diphosphate, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C18H22N6O12P2 (free acid). Mole weight: 576.35 (free acid).
carboxylic acid-CoA ligase (GDP-forming)
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. Group: Enzymes. Synonyms: acyl-CoA synthetase (GDP-forming); acyl coenzyme A synthetase (guanosine diphosphate forming). Enzyme Commission Number: EC 6.2.1.10. CAS No. 37318-59-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5668; carboxylic acid-CoA ligase (GDP-forming); EC 6.2.1.10; 37318-59-5; acyl-CoA synthetase (GDP-forming); acyl coenzyme A synthetase (guanosine diphosphate forming). Cat No: EXWM-5668.
cellulose synthase (GDP-forming)
Involved in the synthesis of cellulose. A similar enzyme [EC 2.4.1.12, cellulose synthase (UDP-forming)] utilizes UDP-glucose. Group: Enzymes. Synonyms: cellulose synthase (guanosine diphosphate-forming); cellulose synthetase; guanosine diphosphoglucose-1,4-β-glucan glucosyltransferase; guanosine diphosphoglucose-cellulose glucosyltransferase; GDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.29. CAS No. 9027-18-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2523; cellulose synthase (GDP-forming); EC 2.4.1.29; 9027-18-3; cellulose synthase (guanosine diphosphate-forming); cellulose synthetase; guanosine diphosphoglucose-1,4-β-glucan glucosyltransferase; guanosine diphosphoglucose-cellulose glucosyltransferase; GDP-glucose:1,4-β-D-glucan 4-β-D-glucosyltransferase. Cat No: EXWM-2523.
diphosphate-purine nucleoside kinase
The enzyme from the Acholeplasma class of Mollicutes catalyses the conversion of adenosine, guanosine and inosine to AMP, GMP and IMP. ATP cannot substitute for diphosphate as a substrate. Group: Enzymes. Synonyms: pyrophosphate-purine nucleoside kinase. Enzyme Commission Number: EC 2.7.1.143. CAS No. 70356-41-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2973; diphosphate-purine nucleoside kinase; EC 2.7.1.143; 70356-41-1; pyrophosphate-purine nucleoside kinase. Cat No: EXWM-2973.
EDA-GDP
EDA-GDP is a paramount nucleotide analogue, proficiently engrossed in DNA reparation. It ardently contributes in the research of maladies associated with DNA impairment, including cancer. Serving as a forerunner in the DNA synthesis pathway, EDA-GDP conspicuously propels the efficacy of reparative mechanisms, thus fostering the rehabilitation of genomic stability. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C13H21N7O12P2(free acid). Mole weight: 529.29 (free acid).
EDA-GDP - ATTO-488
EDA-GDP - ATTO-488 is a fluorescent labeling compound unlocking a myriad of imaging and detection possibilities across diverse applications, including the ever-evolving domains of cell biology and molecular biology research. Specifically engineered to label GTP-binding proteins and proficiently probe GTPase activity, EDA-GDP - ATTO-488 is used for comprehending intricate signaling pathways in various debilitating diseases. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, labeled with ATTO 488, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C38H42N10O21P2S2(free acid). Mole weight: 1100.87 (free acid).
EDA-GDP - ATTO-532
EDA-GDP - ATTO-532, a common fluorescent probe utilized in research on Rho GTPase signaling pathways, proves useful in monitoring small GTPases, specifically Rac1, Cdc42, and RhoA. The said GTPases govern cellular processes, including cell migration, division, and cytoskeleton organization. EDA-GDP - ATTO-532's broad applications also extend to investigating various diseases that relate to Rho GTPase dysregulation, namely cancer, neurological disorders, and developmental abnormalities. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, labeled with ATTO 532, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C42H49N10O21P2S2(free acid). Mole weight: 1155.97 (free acid).
EDA-GDP - ATTO-647N
EDA-GDP - ATTO-647N is a widely applied fluorescent dye conjugate, serving as a remarkable tool for protein, nucleic acid and biomolecule labeling within diverse bioimaging contexts. Its luminous emission, characterized by ATTO-647N, facilitates precise visualization and tracking of distinct molecular entities present in biological specimens. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, labeled with ATTO 647N, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C13H21N7O12P2- ATTO 647N (free acid). Mole weight: 1156.29 (free acid).
EDA-GDP - BDP-FL
EDA-GDP - BDP-FL, a fluorescent probe, is widely employed in scrutinizing GTPase activity and signaling pathways. By monitoring small GTPases and their interactions with proteins, it serves as a reliable tool for investigating various pathophysiological processes, including cancer, where small GTPases have acquired a prominent role in growth and metastasis. Synonyms: also known as BODIPY® FL-GDP; 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, labeled with BODIPY® FL, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C27H34BF2N9O13P2(free acid). Mole weight: 803.37 (free acid).
EDA-GDP - Cy3
EDA-GDP - Cy3 is a highly esteemed fluorescent dye, ingeniously facilitating the research of proteins and nucleic acids. Whether the pursuit involves cell imaging, flow cytometry, or fluorescence microscopy, the utility of EDA-GDP - Cy3 proves indispensably insightful. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, labeled with Cy3, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C44H57N9O19P2S2(free acid). Mole weight: 1142.05 (free acid).
EDA-GDP - Cy5
EDA-GDP - Cy5, an illuminating fluorescent labeling reagent, magnifies the intricacies of cell biology and biomedicine with its remarkable affinity for proteins and protein-protein interactions. This reagent sheds light on the activity of GTPase enzymes implicated in diverse diseases, including cancer. As a luminous ally in biostudies, it dispels the shadows of mystery from the cellular world. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, labeled with Cy5, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C46H59N9O19P2S2(free acid). Mole weight: 1168.09 (free acid).
EDA-m7GDP
EDA-m7GDP emerges as a prominent biochemical entity extensively employed in studying influenza and hepatitis C. This compound assumes a paramount role in inhibiting the replication of virals. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2(free acid). Mole weight: 544.33 (free acid).
EDA-m7GDP - 5/6-TAMRA
EDA-m7GDP - 5/6-TAMRA is a fluorescently labeled ligand used in binding assays to study interaction with GTPases, specifically the RAS family. It is also utilized in studying mRNA decapping enzymes such as the DcpS enzyme. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with 5/6-TAMRA. Grade: ≥ 95 % by HPLC. Molecular formula: C39H43N9O16P2(free acid). Mole weight: 955.76 (free acid).
EDA-m7GDP - 5-FAM
EDA-m7GDP is a small molecule used in the biomedicine industry for the study of RNA processing and modification. It serves as a substrate analog for RNA cap methyltransferase and is used to investigate the role of the cap structure and its modification in RNA processing. EDA-m7GDP is also used in the development of potential antiviral drugs as it inhibits viral RNA cap formation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 5FAM, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C35H33N7O18P2(free acid). Mole weight: 901.63 (free acid).
EDA-m7GDP - 6-FAM
EDA-m7GDP - 6-FAM is a fluorescently labeled analog of the mRNA cap structure, used in biomedicine to study and track mRNA metabolism and protein synthesis. It can also aid in the identification and screening of inhibitors for mRNA capping enzymes, and has potential use in the development of drugs for diseases linked to aberrant mRNA processing, such as cancer and viral infections. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with 6 FAM, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C35H33N7O18P2(free acid). Mole weight: 901.63 (free acid).
EDA-m7GDP - 6-JOE
EDA-m7GDP - 6-JOE, a revered biochemical reagent in the realm of biomedical research, is meticulously employed to scrutinize the immensely intricate cogency of mRNA cap structure in the context of gene expression. Inevitably, the multifarious uses of this mystical compound are riveting, given its intrinsic importance as a formidable inhibitor of cap-dependent translation. Additionally, EDA-m7GDP - 6-JOE is a pragmatic model to study the elusive mechanisms of viral mRNA translation; and to further delve into, with precision, the molecular basis of grievous ailments such as cancer and viral infections. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with 6-JOE, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C37H35Cl2N7O20P2(free acid). Mole weight: 1029.08 (free acid).
EDA-m7GDP - 6-ROX
EDA-m7GDP-6-ROX, a fluorescently-labeled GDP derivative, is a widely-utilized biochemistry research tool for probing the complex interactions involving GTPase-associated proteins and their respective GTPases. Its usage is heavily linked to unraveling intricate signaling pathways implicated in the pathogenesis of dreadful diseases like cancer and neurodegeneration. Through its utilization, valuable insights into the underlying mechanisms of these ailments can be obtained. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with 6-ROX. Grade: ≥ 95 % by HPLC. Molecular formula: C47H51N9O16P2(free acid). Mole weight: 1059.92 (free acid).
EDA-m7GDP - ATTO-390
EDA-m7GDP - ATTO-390 is a fluorescent analog of m7GDP, a cap structure found at the 5' end of mRNA. It can be used to study cap-dependent translation initiation in cells, as well as drug screening assays for compounds that either enhance or inhibit protein synthesis. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 390, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C34H46N8O15P2(free acid). Mole weight: 868.73 (free acid).
EDA-m7GDP - ATTO-425
EDA-m7GDP - ATTO-425, a fluorescent nucleotide analogue widely employed in biochemical studies of RNA metabolism, finds a unique utility in unravelling the molecular intricacies of RNA capping. Of equal significance is its efficacy in monitoring RNA transportation in vivo, rendering it the most sought-after choice in live cell imaging. In essence, EDA-m7GDP - ATTO-425 continues to be an indispensable tool in deciphering RNA's elusive language. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 425, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C36H48N8O17P2(free acid). Mole weight: 926.76 (free acid).
EDA-m7GDP - ATTO-465
EDA-m7GDP - ATTO-465 is a fluorescent nucleotide analog that paves the way for scientists to scrutinize RNA cap structures with great accuracy and precision. This product is widely utilized in the biomedical field, enabling researchers to investigate cap structures on mRNA molecules. Undoubtedly, this is an impressive tool in hunting down the molecular basis of malignant tumors and viral infections. In particular, EDA-m7GDP - ATTO-465's exceptional sensitivity and specificity makes it the first choice for studies of cap structures in RNA and their modification, such as those involved in gene expression regulation and viral escape. Turn to this high-performance product and gain insight into cap structures, opening up novel opportunities for therapeutic development. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 465. Grade: ≥ 95 % by HPLC. Molecular formula: C31H38N10O13P2(free acid). Mole weight: 820.64 (free acid).
EDA-m7GDP - ATTO-488
EDA-m7GDP - ATTO-488 is a fluorescent probe used in biomedical field for studying cellular signaling pathways. It specifically targets m7GDP is a modified nucleotide involved in mRNA capping. This probe enables the visualization and analysis of mRNA capping processes, which play a crucial role in gene expression regulation. It can be utilized for investigating various diseases and drug development related to mRNA metabolism and translation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 488, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C39H44N10O21P2S2(free acid). Mole weight: 1114.16 (free acid).
EDA-m7GDP - ATTO-495
EDA-m7GDP-ATTO-495 - a fluorescent analog recognized for its ability to detect RNA cap structure - has now become a hallmark of research that delves into the intricacies of RNA capping mechanisms. Its invaluable contributions extend beyond that, however, as it also plays a vital role in the study of viral infections - Dengue, West Nile, Zika, and the like - hence making it a valuable asset in the scientific community's quest for knowledge. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 495. Grade: ≥ 95 % by HPLC. Molecular formula: C35H46N10O13P2(free acid). Mole weight: 876.75 (free acid).
EDA-m7GDP - ATTO-532
EDA-m7GDP - ATTO-532 is a fluorescent analog of the 7-methylguanosine diphosphate nucleotide, widely used in biochemical and molecular biology research. This product specifically targets RNA cap-binding proteins, serving as a useful tool for the study of cap-dependent translation initiation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 532, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C43H52N10O21P2S2(free acid). Mole weight: 1171.01 (free acid).
EDA-m7GDP - ATTO-540Q
EDA-m7GDP-ATTO-540Q: a fluorescent derivative of immense value in the field of RNA structural analysis. This compound, revered for its ability to label the cap structures of RNA and detect RNA-labeling within cells, is a critical tool for those studying RNA processing and translational regulation. Scientists worldwide rely upon EDA-m7GDP-ATTO-540Q as a comprehensive fluorescent probe to facilitate their research in the field of RNA structural analysis. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 540Q, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- ATTO 540Q (free acid). Mole weight: 1084.33 (free acid).
EDA-m7GDP - ATTO-550
EDA-m7GDP - ATTO-550, a fluorescent probe commonly employed in the realm of biomedical research, serves as a powerful tool to investigate the intricate interplay between mRNA and translation initiation factors. Through its intrinsic capacity to detect and quantitate eIF4E binding to the mRNA cap structure, this versatile instrument has proven to be of paramount significance in comprehending the underlying mechanisms of cancerous and viral-induced infections. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 550, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 550 (free acid). Mole weight: 1119.33 (free acid).
EDA-m7GDP - ATTO-565
EDA-m7GDP - ATTO-565 is a fluorescently labeled Guanosine diphosphate (GDP) analog used for studying guanine nucleotide binding proteins (G proteins) in biomedical research. It can be utilized in the detection of G protein activation and signaling pathways related to various diseases, including cancer and neurological disorders. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 565. Grade: ≥ 95 % by HPLC. Molecular formula: C45H51N9O16P2(free acid). Mole weight: 1035.89 (free acid).
EDA-m7GDP - ATTO-580Q
EDA-m7GDP - ATTO-580Q is a fluorescent-labeled nucleotide analog used in biomedical research to study the dynamics of mRNA cap structure and protein-RNA interactions. It is commonly used to investigate RNA translation and to screen for potential antiviral drugs targeting cap-dependent translation initiation. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 580Q, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- ATTO 580Q (free acid). Mole weight: 1220.33 (free acid).
EDA-m7GDP - ATTO-590
EDA-m7GDP - ATTO-590, a fluorescent tag of immense utility in the field of biomedical research, grants an opportunity to probe deeper into the intricate interplay between the eukaryotic translation initiation factor 4E (eIF4E) and the mRNA cap structures. The luminosity of the fluorescent tag coupled with the specificity of the binding between eIF4E and the mRNA cap help researchers visualize their interactions in vivo, paving the way for novel insights into the intricate regulation of protein synthesis and new avenues for cancer therapy. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 590. Grade: ≥ 95 % by HPLC. Molecular formula: C51H59N9O16P2(free acid). Mole weight: 1116.02 (free acid).
EDA-m7GDP - ATTO-594
EDA-m7GDP - ATTO-594 is a fluorescent counterpart of the cap structure of mRNA, specifically engineered to investigate RNA processing and transportation. It offer insights into the fundamental mechanisms that regulate these vital cellular activities, enabling researchers to assess intricate interactions between key proteins and enzymes involved in RNA metabolism. Its diverse functionalities make it a promising tool for drug development and studying malignant diseases such as cancer. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 594, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C14H24N7O12P2- ATTO 594 (free acid). Mole weight: 1331.33 (free acid).
EDA-m7GDP - ATTO-612Q
EDA-m7GDP - ATTO-612Q, a fluorescent derivative employed for bioanalytical purposes, finds significant use as an RNA cap structure detection reagent. This molecule is often implemented to investigate the engagement of cap-binding proteins. Its relevance lies in the development of drugs targeted towards cap-binding proteins in pathologies such as viral infections and malignancies. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-7-methyl-guanosine-5'-diphosphate, labeled with ATTO 612Q, Triethylammonium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C14H24N7O15P3- ATTO 612Q (free acid). Mole weight: 1216.33 (free acid).
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