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11-Hydroxy-N-methyldesloratadine is an impurity of Loratadine, which is a histamine H1 receptor antagonist used to treat allergies. Synonyms: 8-Chloro-5,6-dihydro-11-hydroxy-11-(1-methylpiperidin-4-yl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine; 11-Hydroxy-N-methyl Dihydro Loratadine; 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol, 8-chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-; Loratadine Hydroxy deacyl analog; 8-Chloro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol; (11RS)-8-Chloro-11-hydroxy-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine. Grade: ≥95%. CAS No. 38089-93-9. Molecular formula: C20H23ClN2O. Mole weight: 342.86.
11-(N-Hydroxy) Loratadine 1-Oxide
11-(N-Hydroxy) Loratadine 1-Oxide is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Molecular formula: C19H19ClN2O2. Mole weight: 342.82.
12-Fluoro Dihydroloratadine
12-Fluoro Dihydroloratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 4-(8-Chloro-10,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-yl)-4-fluoro-ethyl Ester 1-Piperidinecarboxylic Acid; 1-Piperidinecarboxylic acid, 4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-4-fluoro-, ethyl ester; 1-Piperidinecarboxylic acid, 4-(8-chloro-10,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-5-yl)-4-fluoro-, ethyl ester; Ethyl 4-(8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-4-fluoropiperidine-1-carboxylate. Grade: ≥95%. CAS No. 125743-79-5. Molecular formula: C22H24ClFN2O2. Mole weight: 402.89.
12-Hydoxy Loratadine
12-Hydoxy Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Molecular formula: C22H25ClN2O3. Mole weight: 400.90.
1-[4-[ (4-Chlorophenyl) phenylmethyl]-1-piperazinyl]ethanone Hydrochloride is a derivative of Cetirizine (C281100), a nonsedating type histamine H1-receptor antagonist. Antihystaminic. Group: Biochemicals. Grades: Highly Purified. CAS No. 19178-80-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H21ClN2O; HCl, Molecular Weight: 328.843645999999. US Biological Life Sciences.
An impurity of Azelastine. Azelastine is a selective histamine H1 receptor antagonist used primarily for the treatment of allergic rhinitis and perennial rhinitis, including the relief of nasal congestion, runny nose, sneezing and itchy nose. Synonyms: Benzoic acid, 2-(hexahydro-1-methyl-1H-azepin-4-yl)hydrazide; Azelastine EP impurity B; 1-Benzoyl-2-((4RS)-1-methylhexahydro-1H-azepin-4-yl)diazane; (+/-)-1-Benzoyl-2-(1-methylhexahydro-1H-azepin-4-yl)diazane; Benzoic acid N'-(1-methyl-azepan-4-yl)-hydrazide; Azelastine Hydrochloride Impurity B. Grade: 95%. CAS No. 110406-94-5. Molecular formula: C14H21N3O. Mole weight: 247.34.
(1-Benzylpiperidin-4-yl)diphenyl-d10-methanol
(1-Benzylpiperidin-4-yl)diphenyl-d10-methanol is an intermediate in the synthesis of Fexofenadine-d10 Hydrochloride, the labeled analogue of Fexofenadine Hydrochloride (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C25H17D10NO, Molecular Weight: 367.55. US Biological Life Sciences.
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1-Methylazepan-4-one
1-Methylazepan-4-one is a methyl derivative of Azepan-4-one (A809755, HCl) and a useful synthetic intermediate in the synthesis of N-Methyl-4-[1- (4-chlorophenyl) -1-phenylethoxy) hexahydroazepine (M295095); an impurity in the synthesis of Clemastine Fumarate (C568500) which is a H1 histamine receptor antagonist and antihistaminic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1859-33-2. Pack Sizes: 250mg, 2.5g. Molecular Formula: C7H13NO, Molecular Weight: 127.18. US Biological Life Sciences.
Worldwide
1-Oxo Fexofenadine-d10 Methyl Ester
1-Oxo Fexofenadine-d10 Methyl Ester is the labeled analogue of 1-Oxo Fexofenadine Methyl Ester (O870040), an intermediate in the preparation of Fexofenadine (F322470). It can also be used for the synthesis of an oxidation metabolite of Terfenadine (T114500),a H1-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C33H29D10NO4, Molecular Weight: 523.73. US Biological Life Sciences.
2- [ [ (1, 1-dimethylethyl) dimethylsilyl] oxy] propanoic Acid Ethyl Ester is an intermediate in the synthesis of Cetirizine (C291155), an nonsedating type histamine H1-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 105198-38-7. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H24O3Si. US Biological Life Sciences.
2- (2- (4- ( (4-Chlorophenyl) (phenyl) methyl) piperazin-1-yl) ethoxy) acetic Acid sodium salt is an intermediate in the synthesis of Cetirizine (C291155), an nonsedating type histamine H1-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 130018-91-6. Pack Sizes: 25mg, 100mg. Molecular Formula: C21H24ClN2NaO3. US Biological Life Sciences.
Worldwide
2-[2-(Dimethylamino)ethyl]-1-indanone
An impurity of Dimethindene. Dimethindene is a potent antihistamine with antipruritic properties, commonly used to treat allergies, itching, and nasal congestion. Uses: Dimethindene impurity, a histaminic h1 receptor antagonist. Synonyms: 2-[2-(Dimethylamino)ethyl]-2,3-dihydro-1H-inden-1-one; 2-(2-Dimethylamino-ethyl)-indan-1-one; Dimetindene EP Impurity E; Dimetindene Impurity E; (2RS)-2-[2-(Dimethylamino)ethyl]-2,3-dihydro-1H-inden1-one. Grade: ≥95%. CAS No. 3409-21-0. Molecular formula: C13H17NO. Mole weight: 203.28.
2,3-Dihydroxy Desloratadine
2,3-Dihydroxy Desloratadine is a derivative of Desloratadine (D290250) which is a nonsedating-type histamine H1-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H19ClN2O2, Molecular Weight: 342.82. US Biological Life Sciences.
Worldwide
2,3-Dihydroxy Desloratadine 3-Glucuronide
2,3-Dihydroxy Desloratadine 3-Glucuronide is one of loratadine metabolites. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: Dihydroxy Desloratadine 3-β-D-Glucuronide. Molecular formula: C25H27ClN2O8. Mole weight: 518.95.
2- (4- (4- (4- (Diphenylmethylene) piperidin-1-yl) butanoyl) phenyl) -2-methylpropanoic Acid Methyl Ester is an impurity of fexofenadine (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 1025909-08-3. Pack Sizes: 100mg, 1g. Molecular Formula: C33H37NO3. US Biological Life Sciences.
[2- [4- [ (4-Chlorophenyl) phenylmethyl] -1-piperazinyl] ethoxy] acetyl Chloride is an intermediate in the synthesis of Cetirizine (C281100), a non-sedating type histamine H1-receptor antagonist whose activity lies in the (R) Isomer primarily. Group: Biochemicals. Grades: Highly Purified. CAS No. 776284-33-4. Pack Sizes: 25mg, 100mg. Molecular Formula: C21H24Cl2N2O2. US Biological Life Sciences.
[2- [4- [ (4-Chlorophenyl) phenylmethyl] -1-piperazinyl] ethoxy] acetyl Chloride Dihydrochloride is an intermediate in the synthesis of Cetirizine (C291155), an nonsedating type histamine H1-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 324047-28-1. Pack Sizes: 50mg, 100mg. Molecular Formula: C21H24Cl2N2O2. US Biological Life Sciences.
2-[ (4-Chlorophenyl) (4-piperidinyloxy) methyl]pyridine is an intermediate in the synthesis of Bepotastine besylate (B317000), a non-sedating H1-antagonist that has anti-inflammatory activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 122368-54-1. Pack Sizes: 2.5g, 10g. Molecular Formula: C17H19ClN2O. US Biological Life Sciences.
Worldwide
2-Chloro Loratadine
2-Chloro Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 4-(2,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(2,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate; ethyl 4-(2,8-dichloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-c]pyridin-11-ylidene)piperidine-1-carboxylate. Grade: 95%. CAS No. 165739-64-0. Molecular formula: C22H22Cl2N2O2. Mole weight: 417.33.
2-Cyano Loratadine
2-Cyano Loratadine is an intermediate in the synthesis of Loratadine, which is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: Intermediate for the synthesis of 2-hydroxymethyl loratadine. Synonyms: 4-(8-Chloro-2-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Loratadine 2-Nitrile; Ethyl 4-(8-chloro-2-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 4-(8-chloro-2-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester. Grade: ≥95%. CAS No. 860010-31-7. Molecular formula: C23H22ClN3O2. Mole weight: 407.89.
2-Decarboxymethyl-2-formyl E-Olopatadine Hydrochloride is an impurity of Olopatadine Hydrochloride (O575000) which is a dual acting histamine H1-receptor antagonist and mast cell stabilizer. Antiallergic; antihistaminic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C20H22ClNO2, Molecular Weight: 343.85. US Biological Life Sciences.
Worldwide
2-Formyl Loratadine
2-Formyl Loratadine is a by-product of Loratadine, which is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: A by-product of 2-hydroxymethyl loratadine. Synonyms: 4-(8-Chloro-2-formyl-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(8-chloro-2-formyl-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate. Grade: ≥95%. CAS No. 1076198-15-6. Molecular formula: C23H23ClN2O3. Mole weight: 410.89.
2-Hydroxy Fenspiride
A metabolite of Fenspiride. Fenspiride is an α adrenergic and H1 histamine receptor antagonist. Synonyms: 8-[2-(2-Hydroxyphenyl)ethyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one. Grade: > 95%. CAS No. 441781-21-1. Molecular formula: C15H20N2O3. Mole weight: 276.34.
2-Hydroxymethyl Loratadine
2-Hydroxymethyl Loratadine is an impurity of Loratadine, which is a histamine H1 receptor antagonist used to treat allergies. Synonyms: Ethyl 4-[8-chloro-5,6-dihydro-2-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylate; 4-[8-Chloro-5,6-dihydro-2-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Ester; 1-Piperidinecarboxylic acid, 4-[8-chloro-5,6-dihydro-2-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-, ethyl ester; Loratadine 2-Hydroxymethyl Impurity (USP). Grade: ≥95%. CAS No. 609806-39-5. Molecular formula: C23H25ClN2O3. Mole weight: 412.91.
2-Methoxycarbonyl loratadine
2-Methoxycarbonyl loratadine is an intermediate for the synthesis of Loratadine, which is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: Intermediate for the synthesis of 2-hydroxymethyl loratadine. Synonyms: 8-Chloro-11-[1-(ethoxycarbonyl)-4-piperidinylidene]-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-2-carboxylic Acid Methyl Ester; Methyl 8-chloro-11-[1-(ethoxycarbonyl)-4-piperidinylidene]-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-2-carboxylate; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine-2-carboxylic acid, 8-chloro-11-[1-(ethoxycarbonyl)-4-piperidinylidene]-6,11-dihydro-, methyl ester. Grade: ≥95%. CAS No. 860010-37-3. Molecular formula: C24H25ClN2O4. Mole weight: 440.92.
2-Oxopropyl 2- (2- (4- ( (4-Chlorophenyl) (phenyl) methyl) piperazin-1-yl) ethoxy) acetate is an intermediate in the synthesis of Cetirizine (C291155), an nonsedating type histamine H1-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C24H29ClN2O4. US Biological Life Sciences.
2-?[ (RS) ?-? (4-?Methylphenyl) ?phenylmethoxy]?-?N, ?N-?dimethylethanamine Hydrochloride is an impurity of Diphenhydramine (D486900), is an H1-histamine receptor antagonist. Diphenhydramine is categorized as an antihistaminic; sedative, hypnotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 4024-34-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C18H23NO; (HCl). US Biological Life Sciences.
An impurity of Bepotastine besylate, a histamine H1 receptor antagonist that has been approved in Japan for the treatment of allergic rhinitis and uriticaria/puritus. Synonyms: 2-[(S)-(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine L-Tartrate. CAS No. 210095-58-2. Molecular formula: C17H19ClN2O.C4H6O6. Mole weight: 452.89.
2-[ (S) - (4-Chlorophenyl) (4-piperidinyloxy) methyl]pyridine L-Tartrate
2-[ (S) - (4-Chlorophenyl) (4-piperidinyloxy) methyl]pyridine (2R,3R)-2,3-dihydroxybutanedioate is used as a reagent to prepare optically active 4-[ (4-chlorophenyl-2-pyridyl) methoxy]piperidine, a compound that is used as an intermediate in the synthesis of antihistamines and antiallergy agents. (S) -2-[ (4-Chlorophenyl) (4-piperidinyloxy) methyl]pyridine is also an intermediate of Bepotastine besylate (B317000), a non-sedating H1-antagonist that has anti-inflammatory activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 210095-58-2. Pack Sizes: 5g, 25g. Molecular Formula: C21H25ClN2O7. US Biological Life Sciences.
Worldwide
2- (tert-Butyldi methyl silanyloxy) propan-1-ol
2- (tert-Butyldi methyl silanyloxy) propan-1-ol is an intermediate in the synthesis of Cetirizine (C291155), an nonsedating type histamine H1-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 142072-07-9. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H22O2Si. US Biological Life Sciences.
3-Bromo-8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is one of loratadine intermediates. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 3-bromo-8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-one; 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 3-bromo-8-chloro-5,6-dihydro-. Grade: ≥95%. CAS No. 156073-28-8. Molecular formula: C14H9BrClNO. Mole weight: 322.58.
3-Hydroxy Desloratadine
3-Hydroxy Desloratadine is an active metabolite of Loratadine, which is a nonsedating-type histamine H1 receptor antagonist, used to treat allergies. Synonyms: 3-hydroxydesloratadine; 8-Chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol. Grade: > 95%. CAS No. 119410-08-1. Molecular formula: C19H19ClN20. Mole weight: 326.82.
3-Hydroxy Desloratadine Dihydrochloride Hydrate
3-Hydroxy Desloratadine Dihydrochloride Hydrate is one of loratadine metabolites. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol Dihydrochloride Hydrate; 3-Hydroxydesloratadine Dihydrochloride Hydrate; Sch 45581 Dihydrochloride Hydrate. Molecular formula: C19H23Cl3N2O2. Mole weight: 417.76.
3-Hydroxy Loratadine
3-Hydroxy Loratadine is an intermediate for the preparation of Loratadine, which is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: An intermediate for the preparation of 3-hydroxy desloratadine. Synonyms: 4-(8-Chloro-5,6-dihydro-3-hydroxy-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-3-hydroxy-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester; 3-hydroxyloratadine; Ethyl 4-(8-chloro-3-hydroxy-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate. Grade: 95%. CAS No. 183483-15-0. Molecular formula: C22H23ClN2O3. Mole weight: 398.88.
3-Methoxy loratadine
3-Methoxy loratadine is a derivative of Loratadine, which is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: Useful as inhibitor of both farnesyl protein transferase and geranylgeranyl protein transferase in the treatment of cell-proliferative diseases. Synonyms: 4-(8-Chloro-5,6-dihydro-3-methoxy-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-3-methoxy-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester; 3-methoxyloratadine; Ethyl 4-(8-chloro-3-methoxy-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate. Grade: ≥95%. CAS No. 165739-73-1. Molecular formula: C23H25ClN2O3. Mole weight: 412.91.
An impurity of Azelastine. Azelastine is a selective histamine H1 receptor antagonist used primarily for the treatment of allergic rhinitis and perennial rhinitis, including the relief of nasal congestion, runny nose, sneezing and itchy nose. Grade: ≥95%. CAS No. 53242-89-0. Molecular formula: C20H20ClN3O. Mole weight: 353.85.
4-(8-Chloro-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11(6H)-ylidene)piperidin-1-yl Benzoate is an protected intermediate in the synthesis of Desloratadine (D290250), an nonsedating-type histamine H1-receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one is an impurity of Loratadine, which is a histamine H1 receptor antagonist used to treat allergies. Synonyms: 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 4,8-dichloro-5,6-dihydro-; 4,8-Dichloro-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-one; Dichlorobenzocycloheptapyridinone; Loratadine Impurity. Grade: ≥95%. CAS No. 133330-60-6. Molecular formula: C14H9Cl2NO. Mole weight: 278.13.
4-Cyano Loratadine
4-Cyano Loratadine is an intermediate in the synthesis of Loratadine, which is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: Intermediate for the synthesis of 4-hydroxymethyl loratadine. Synonyms: 4-(8-Chloro-4-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-Piperidinecarboxylic Acid Ethyl Ester; Loratadine 4-Nitrile; Ethyl 4-(8-chloro-4-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 4-(8-chloro-4-cyano-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester. Grade: ≥95%. CAS No. 860010-33-9. Molecular formula: C23H22ClN3O2. Mole weight: 407.89.
4-Formyl Loratadine
4-Formyl Loratadine is a by-product of Loratadine, which is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: A by-product of 4-hydroxymethyl loratadine. Synonyms: 4-(8-Chloro-4-formyl-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(8-chloro-4-formyl-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate. Grade: ≥95%. CAS No. 1076198-16-7. Molecular formula: C23H23ClN2O3. Mole weight: 410.89.
4-Hydroxymethyl Loratadine
4-Hydroxymethyl Loratadine is an impurity of Loratadine, which is a histamine H1 receptor antagonist used to treat allergies. Synonyms: Ethyl 4-[8-chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylate; 1-Piperidinecarboxylic acid, 4-[8-chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-, ethyl ester; 4-[8-Chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Ester. Grade: ≥95%. CAS No. 609806-40-8. Molecular formula: C23H25ClN2O3. Mole weight: 412.91.
4-Hydroxymethyl Loratadine Hydrochloride
4-Hydroxymethyl Loratadine Hydrochloride is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: Ethyl 4-[8-chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylate Hydrochloride; 1-Piperidinecarboxylic acid, 4-[8-chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-, ethyl ester, hydrochloride (1:1); 4-[8-Chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Ester Hydrochloride. Grade: 92%. Molecular formula: C23H26Cl2N2O3. Mole weight: 449.37.
5,6-Dehydro-N-methyl Desloratadine
5,6-Dehydro-N-methyl Desloratadine is one of Loratadine derivatives. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: A derivative of loratadine as dual antagonist of platelet activating factor (paf) and histamine. Synonyms: 8-chloro-11-(1-methyl-4-piperidinylidene)-11H-benzo[5,6]cyclohepta[1,2-b]pyridine; Loratadine Impurity 32. Grade: ≥95%. CAS No. 117811-18-4. Molecular formula: C20H19ClN2. Mole weight: 322.83.
5-Hydroxyindole-3-acetic Acid
HIAA is an antagonist of histamine H1 receptor that is used to treat allergies. Synonyms: 2-(5-hydroxy-1H-indol-3-yl)acetic acid; 2-(5-hydroxy-1H-indol-3-yl)acetic acid. CAS No. 54-16-0. Molecular formula: C10H9NO3. Mole weight: 191.18.
5-Hydroxyindole-3-acetic Acid-[d2]
5-Hydroxyindole-3-acetic Acid-[d2] is the labelled analogue of 5-Hydroxyindole-3-acetic Acid, which is an impurity of Chlorpheniramine. Chlorpheniramine is a histamine H1 receptor antagonist that is used to treat allergy symptoms. Synonyms: 5-Hydroxyindole-3-acetic Acid D2; (5-Hydroxy-1H-indol-3-yl)acetic Acid-D2; 5-HIAA-D2; 5-Hydroxy-1H-indole-3-acetic Acid-D2; 5-Hydroxy-3-indolylacetate-D2; 5-Hydroxy-IAA-D2; 5-Hydroxyheteroauxin-D2; 5-Hydroxyindol-3-ylacetic Acid-D2; 5-Hydroxyindoleacetic Acid-D2; 5-Oxyindoleacetic Acid-D2; NSC 90432-D2. Grade: ≥98%; ≥99% atom D. CAS No. 56209-31-5. Molecular formula: C10H7D2NO3. Mole weight: 193.20.
5-Methoxy-3-methyl-2-pyridinecarbonitrile
5-Methoxy-3-methyl-2-pyridinecarbonitrile is one of loratadine intermediates. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 5-Methoxy-3-methylpicolinonitrile; 2-Pyridinecarbonitrile, 5-methoxy-3-methyl-; 2-Cyano-5-methoxy-3-methylpyridine. Grade: ≥95%. CAS No. 1256792-12-7. Molecular formula: C8H8N2O. Mole weight: 148.16.
8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]-11-pyridinol. Grade: 98%. CAS No. 117811-17-3. Molecular formula: C20H21ClN2O. Mole weight: 340.85.
8-chloro-11H-benzo[5,6]cyclo-hepta[1,2-b]pyridin-11-one is one of loratadine intermediates. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: Desloratadine Impurity 20; 13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-2-one; Desloratadine Dehydro 11-Oxo Impurity; 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 8-chloro-. Grade: ≥95%. CAS No. 117811-16-2. Molecular formula: C14H8ClNO. Mole weight: 241.67.
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 1-Oxide is an intermediate for the preparation of Loratadine, which is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: Intermediate for the preparation of loratadine impurities. Synonyms: 8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one N1-Oxide; 8-chloro-1-oxido-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-1-ium-11-one; 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 8-chloro-5,6-dihydro-, 1-oxide. Grade: ≥95%. CAS No. 133330-59-3. Molecular formula: C14H10ClNO2. Mole weight: 259.69.
8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 8-Chloro-5,6-dihydro-11H-benzo-[5,6]-cyclohepta-[1,2-b]-pyridin-11-ol; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol, 8-chloro-6,11-dihydro-. CAS No. 133330-72-0. Molecular formula: C14H12ClNO. Mole weight: 245.71.
8-Dechloro-10-chloro Desloratadine
8-Dechloro-10-chloro Desloratadine is one of Loratadine metabolites. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 10-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 10-chloro-6,11-dihydro-11-(4-piperidinylidene)-; 10-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; Desloratadine Impurity 3. Grade: 98%. CAS No. 1346600-61-0. Molecular formula: C19H19ClN2. Mole weight: 310.82.
8-Dechloro-10-chloro Loratadine
8-Dechloro-10-chloro Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 4-(10-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(10-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxyate. Grade: > 98%. CAS No. 1346605-16-0. Molecular formula: C22H23ClN2O2. Mole weight: 382.88.
8-Dechloro-7-chloro Desloratadine
8-Dechloro-7-chloro Desloratadine is one of Loratadine metabolites. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 7-chloro-6,11-dihydro-11-(4-piperidinylidene)-; 7-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; Desloratadine Impurity 1; 7-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine. Grade: 98%. CAS No. 1346601-53-3. Molecular formula: C19H19ClN2. Mole weight: 310.82.
8-Dechloro-7-chloro Loratadine
8-Dechloro-7-chloro Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 4-(7-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(7-Chloro-5,6-dihydro-11H-benzo[5,6] cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxyate. Grade: > 98%. CAS No. 1346602-19-4. Molecular formula: C22H23ClN2O2. Mole weight: 382.88.
8-Dechloro-7-chloro-N-methyl Desloratadine
8-Dechloro-7-chloro-N-methyl Desloratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 7-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; Desloratadine Impurity 4. Grade: 98%. CAS No. 1346600-30-3. Molecular formula: C20H21ClN2. Mole weight: 324.85.
8-Dechloro-9-chloro Loratadine
8-Dechloro-9-chloro Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: Loratadine (l469575) impurity. Synonyms: 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxyate. Grade: > 98%. CAS No. 109537-11-3. Molecular formula: C22H23ClN2O2. Mole weight: 382.88.
8-Deschloro-8-bromo Loratadine
8-Deschloro-8-bromo Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Grade: 98%. CAS No. 130642-60-3. Molecular formula: C22H23BrN2O2. Mole weight: 427.33.
8-Deschloro-8-bromo-N-methyl Desloratadine
8-Deschloro-8-bromo-N-methyl Desloratadine is one of Loratadine derivatives. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 8-Bromo-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 8-Bromo-11-(1-methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-bromo-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-; Desloratadine Impurity 18. Grade: ≥95%. CAS No. 130642-57-8. Molecular formula: C20H21BrN2. Mole weight: 369.30.
A 987306
A 987306 is a potent histamine H4 receptor antagonist (pKi = 8.24 and 8.47 in human and rat H4 receptors, respectively) with 162-, 620-, and > 1600-fold selectivity over human H3, H1 and H2 receptors. It suppresses zymosan-induced neutrophil reflux and attenuates thermal hypersensitivity in vivo (ED50 = 42 μmol/kg, ip). Synonyms: A 987306; A987306; A-987306; (±)-(7aR,11aR)-5,6,7a,8,9,10,11,11a-Octahydro-4-(1-piperazinyl)-benzofuran[2,3-h]quinazolin-2-amine. Grade: ≥98% by HPLC. CAS No. 1082954-71-9. Molecular formula: C18H25N5O. Mole weight: 327.42.
aceprometazine
Aceprometazine is a Histamine H1 receptor antagonist as an approved drug. It can be used in combination with meprobamate for the treatment of sleep disorders such as Insomnia. Uses: Insomnia. Synonyms: Mepronizine; Acepromethazine; Aceprometazine; Aceprometazina; Aceprometazinum; Aceprometazinum; Aceprometazina; 1-[10-[2-(Dimethylamino)propyl]-10H-phenothiazin-2-yl]ethanone; Acepromethazine. Grade: 95%. CAS No. 13461-01-3. Molecular formula: C19H22N2OS. Mole weight: 326.46.
Acrivastine
Acrivastine, also known as BW825C, is an antihistamine with peripheral H1-antagonist potency equal to that of triprolidine for the treatment of allergic rhinitis. Synonyms: (E)-3-[6-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridin-2-yl]prop-2-enoic acid; acrivastine; BW 825C; BW-825C; BW825C; Glaxo Wellcome brand of acrivastine; GlaxoSmithKline brand of acrivastine; Semprex. CAS No. 87848-99-5. Molecular formula: C22H24N2O2. Mole weight: 348.44.
Alcaftadine
Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis. Uses: Histamine h1 antagonists. Synonyms: Lastacaft. Grade: 0.98. CAS No. 147084-10-4. Molecular formula: C19H21N3O. Mole weight: 307.397.
Alcaftadine
Alcaftadine (R89674) is a histamine H1 receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis. Alcaftadine is a broad-spectrum antihistamine displaying a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. Alcaftadine also exhibits modulatory action on immune cell recruitment and mast cell stabilizing effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R89674. CAS No. 147084-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17039.
Alcaftadine-[d3]
Alcaftadine-[d3] is the labelled analogue of Alcaftadine, which is an H1 histamine receptor antagonist used to treat eye irritation caused by allergic conjunctivitis. Synonyms: Alcaftadine D3; 6,11-Dihydro-11-[1-(methyl-d3)-4-piperidinylidene]-5H-imidazo[2,1-b][3]benzazepine-3-carboxaldehyde; R 89674-d3; Lastacaft-d3. Grade: >95%. CAS No. 1794775-80-6. Molecular formula: C19H18D3N3O. Mole weight: 310.42.
Amthamine dihydrobromide
Amthamine dihydrobromide is the dihydrobromide salt of amthamine, which is a highly selective histamine H2 receptor agonist. It is a weak antagonist at H3 and has no activity at H1 receptors. It decreases myogenic tone and induces vasodilation of cerebral arteries in vitro. It can be used in the suppression of the release of serotonin and H2 receptor-mediated eosinophil peroxidase (EPO). It has been used to study the effect of mast cells on T regulatory cell function. Synonyms: 5-(2-Aminoethyl)-4-methylthiazol-2-amine Dihydrobromide; A 4730 Dihydrobromide; 2-Amino-4-methyl-5-thiazoleethanamine dihydrobromide; 2-Amino-5-(2-aminoethyl)-4-methylthiazole dihydrobromide. Grade: ≥99% by HPLC. CAS No. 142457-00-9. Molecular formula: C6H13N3SBr2. Mole weight: 319.06.
Antazoline
Antazoline is a first-generation antihistamine, binding to the histamine H1 receptor and blocking the action of endogenous histamine. Antazoline has a sedative effect and is used to prevent the typical allergic symptoms caused by histamine activities on capillaries, skin, mucous membranes, gastrointestinal and bronchial smooth muscles. Uses: Anti-allergic agents; histamine h1 antagonists. Synonyms: Benzyl-(4,5-dihydro-1H-imidazol-2-ylmethyl)-phenyl-amine; Phenazoline; Antasten; Antistin; Antastan; Antihistal; Antistine; Histostab; Imidamine; 2-(N-Phenyl-N-benzylaminomethyl)imidazoline; 2-(N-Benzylanilinomethyl)-2-imidazoline; 4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine; 2-Phenyl-benzyl-amino-methylimidazolin; 1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)-. Grade: 95%. CAS No. 91-75-8. Molecular formula: C17H19N3. Mole weight: 265.36.
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