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| Product | Description | |
|---|---|---|
| Halofuginone | Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibro-proliferative diseases. Uses: Semisynthetic quinazolinone alkaloid anticoccidial. Synonyms: Halofuginone; Tempostatin; RU 19110; RU19110; RU-19110. Grades: > 95%. CAS No. 55837-20-2. Molecular formula: C16H17BrClN3O3. Mole weight: 414.684. |  |
| Halofuginone | Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K i of 18.3 nM [1] [2]. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity [3] [4]. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca 2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects [5]. Uses: Scientific research. Group: Natural products. Alternative Names: RU-19110. CAS No. 55837-20-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1584. |  |
| Halofuginone | Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-bromo-6-chloro-3-[3-[(2r,3s)-3-hydroxy-2-piperidyl]-2-oxopropyl]-4(3h)-quinazolinone;HALOFUGINONE;4(3h)-quinazolinone,7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropy;7-Bromo-6-chloro-3[3-(3-hydroxy-2-piperidi-nyl)-2-oxopropyl]-4(3H)-quinzolinone;trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-4(3h)-qui;trans-l);7-Bromo-6-chloro-3-(3-(3-hydroxypiperidin-2-yl)-2-oxopropyl)quinazolin-4(3H)-one;7-Bromo-6-chlorofebrifugine Hydrochloride. Product Category: Inhibitors. Appearance: Solid. CAS No. 55837-20-2. Molecular formula: C16H17BrClN3O3. Mole weight: 414.68. Purity: 0.9978. Canonical SMILES: O=C1N(CC(C[C@@H]2NCCC[C@H]2O)=O)C=NC3=C1C=C(Cl)C(Br)=C3. Product ID: ACM55837202. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Halofuginone (7-Bromo-6-Chlorofebrifunine, HAL, rel-7-Bromo-6-chloro-3-[3-(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4((3H)-quinazolinone) | Halogenated derivative of febrigugine. Used as an antiprotozoal. Group: Biochemicals. Alternative Names: 7-Bromo-6-Chlorofebrifunine, HAL, rel-7-Bromo-6-chloro-3-[3-(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4((3H)-quinazolinone. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Halofuginone hydrobromide | Halofuginone hydrobromide. Group: Biochemicals. Alternative Names: rel-7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone hydrobromide; trans-(+/-)-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4(3H)-quinazolinone monohydrobromide; RU 19110. Grades: Highly Purified. CAS No. 64924-67-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C16H18Br2ClN3O3. US Biological Life Sciences. | Worldwide |
| Halofuginone hydrobromide | Halofuginone hydrobromide is a salt form of Halofuginone, which is a coccidiostat used in veterinary medicine. Synonyms: DL-trans-7-Bromo-6-chloro-3-[3-(3-hydroxypiperidin-2-yl)-2-oxopropyl]-3H-quinazolin-4-one hydrobromide. CAS No. 64924-67-0. Molecular formula: C16H18Br2ClN3O3. Mole weight: 495.596. | |
| Halofuginone hydrobromide | Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K i of 18.3 nM [1] [2]. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity [3] [4]. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca 2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects [5]. Uses: Scientific research. Group: Natural products. Alternative Names: RU-19110 hydrobromide. CAS No. 64924-67-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N1584A. | |
| Halofuginone hydrochloride | Halofuginone hydrochloride. Group: Biochemicals. Alternative Names: rel-7-Bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone hydrochloride; 7-Bromo-6-chlorofebrifugine hydrochloride; HAL. Grades: Highly Purified. CAS No. 1217623-74-9. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C16H17BrClN3O3·HCl. US Biological Life Sciences. | Worldwide |
| Halofuginone Hydrochloride | Halofuginone Hydrochloride is the hydrochloride salt preparation of Halofuginone. Synonyms: rel-7-Bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone Hydrochloride; 7-Bromo-6-chlorofebrifugine Hydrochloride; HAL. Grades: > 95%. CAS No. 1217623-74-9. Molecular formula: C16H18BrCl2N3O3. Mole weight: 451.15. | |
| Halofuginone lactate | Halofuginone lactate, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K i of 18.3 nM [1] [2]. Halofuginone lactate is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity [3] [4]. Halofuginone lactate is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca 2+ channels. Halofuginone lactate has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU-19110 lactate. CAS No. 82186-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1584C. | |
| Halofuginone lactate | Halofuginone lactate. Group: Biochemicals. Grades: Highly Purified. CAS No. 82186-71-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C19H23BrClN3O6. US Biological Life Sciences. | Worldwide |
| Halofuginone lactate | Halofuginone lactate is a halogenated derivative of febrifugine. Halofuginone inhibits prolyl-tRNA synthetase in an ATP-dependent manner with a Ki of 18.3 nM. Grades: >95%. CAS No. 82186-71-8. Molecular formula: C19H23BrClN3O6. Mole weight: 504.76. | |
| Halofuginone Lactate | Halofuginone Lactate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 82186-71-8. Molecular Formula: C19H23BrClN3O6. Mole Weight: 504.76. Catalog: APB82186718. |  |
| Halofuginone (Standard) | Halofuginone (Standard) is the analytical standard of Halofuginone. This product is intended for research and analytical applications. Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM [1] [2]. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity [3] [4]. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects [5]. Uses: Scientific research. Group: Natural products. CAS No. 55837-20-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1584R. | |
| cis-Halofuginone | cis-Halofuginone. Group: Biochemicals. Alternative Names: rel-7-bromo-6-chloro-3-[[(3aS,7aS)-octahydro-2-hydroxyfuro[3,2-b]pyridin-2-yl]methyl]-4(3H)-quinazolinone. Grades: Highly Purified. CAS No. 1273594-72-1. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C16H17BrClN3O3. US Biological Life Sciences. | Worldwide |
| N,O-Bis(benzyloxycarbonyl) Halofuginone | Protected Halofuginone. Group: Biochemicals. Alternative Names: (2R, 3S) -rel-2-[3- (7-Bromo-6-chloro-4-oxo-3 (4H) -quinazolinyl) -2-oxopropyl]-3-[[ (phenylmethoxy) carbonyl]oxy]-1-piperidinecarboxylic Acid Phenylmethyl Ester. Grades: Highly Purified. CAS No. 1246816-41-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 7-Bromo-6-chloro-4(3H)-quinazolinone | 7-Bromo-6-chloro-4(3H)-quinazolinone is an important intermediate in the manufacturing of the anticoccidial drug (coccidiostat) halofuginone (Tempostatin). Group: Biochemicals. Alternative Names: 7-Bromo-6-chloro-4(1H)-quinazolinone. Grades: Highly Purified. CAS No. 17518-98-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Allyl Bromoridane | Allyl Bromoridane is used as an anticoccidial agent. Allyl Bromoridane is an intermediate of Febrifugine and Halofuginone. Group: Biochemicals. Alternative Names: trans-2-(3-Bromo-2-oxopropyl)-3-methoxy-1-piperidinecarboxylic Acid 2-Propenyl Ester. Grades: Highly Purified. CAS No. 117348-70-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bromoridane Hydrobromide | Bromoridane is a piperidylpropanone derivative having anti-coccidiosis activity. Bromoridane is an intermediate of Febrifugine and Halofuginone. Group: Biochemicals. Alternative Names: trans-. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| (-)-Deoxyhalofebrifugine Dihydrobromide | (-)-Deoxyhalofebrifugine is an analog of Halofuginone (H102500, HCl salt), a halogenated derivative of Febrifugine (F228500). Halofuginone is used as an antiprotozoal. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C16H19Br3ClN3O2, Molecular Weight: 560.51. US Biological Life Sciences. | Worldwide |
| (+)-Deoxyhalofebrifugine Dihydrobromide | (+)-Deoxyhalofebrifugine is an analog of Halofuginone (H102500, HCl salt), a halogenated derivative of Febrifugine (F228500). Halofuginone is used as an antiprotozoal. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C16H19Br3ClN3O2, Molecular Weight: 560.51. US Biological Life Sciences. | Worldwide |
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