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| Product | Description | |
|---|---|---|
| HATU | A peptide coupling reagent. Group: Biochemicals. Alternative Names: 1-[Bis (dimethylamino) methylene]-1H-1, 2, 3-triazolo[4, 5-b]pyridinium 3-Oxide Hexafluorophosphate. Grades: Highly Purified. CAS No. 148893-10-1. Pack Sizes: 5g. US Biological Life Sciences. |  Worldwide |
| HATU | HATU (1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base (N,N-diisopropylethylamine, DIPEA) to form amide bonds [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148893-10-1. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-Y1703. |  |
| HATU | HATU, a triazolopyridine dirivative, has been found to be a peptide coupling reagent and could be used in the formation of of Aurora A kinase inhibitors. Synonyms: HATU; 2-(7-Aza-1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate; O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; 1H-1,2,3-Triazolo[4,5-b]pyridinium, 1-[bis(dimethylamino)methylene]-, 3-oxide, hexafluorophosphate(1-) (1:1); O-(7-Azabenzotriazol-1-yl)-N,N,N,N-tetramethyl uronium hexafluorophosphate; 1H-1,2,3-Triazolo[4,5-b]pyridinium, 1-[bis(dimethylamino)methylene]-, hexafluorophosphate(1-), 3-oxide; 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxide hexafluorophosphate. Grade: 98%. CAS No. 148893-10-1. Molecular formula: C10H15F6N6OP. Mole weight: 380.23. |  |
| HATU | Similar to HBTU, but reacts faster with less epimerization during coupling. Nevertheless, HATU is preferred to HBTU in most rapid coupling protocols (while it is utilized in the same manner as HBTU). Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 1- [Bis (Dimethylamino) Methylene] -1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate. CAS No. 148893-10-1. |  Luxembourg Bio Technologies |
| O-(7-Azabenzotriazol-1-yl)-N,N,N',N'- tetramethyluronium hexafluorophosphate (HATU) | 1g Pack Size. Group: Biochemicals, Peptide Reagents. Formula: C10H15F6N6OP. CAS No. 148893-10-1. Prepack ID 40746229-1g. Molecular Weight 380.23. See USA prepack pricing. |  |
| O-(7-Azabenzotriazol-1-yl)-N,N,N',N'- tetramethyluronium hexafluorophosphate (HATU) | 25g Pack Size. Group: Biochemicals, Peptide Reagents. Formula: C10H15F6N6OP. CAS No. 148893-10-1. Prepack ID 40746229-25g. Molecular Weight 380.23. See USA prepack pricing. | |
| O-(7-Azabenzotriazol-1-yl)-N,N,N',N'- tetramethyluronium hexafluorophosphate (HATU) | 5g Pack Size. Group: Biochemicals, Peptide Reagents. Formula: C10H15F6N6OP. CAS No. 148893-10-1. Prepack ID 40746229-5g. Molecular Weight 380.23. See USA prepack pricing. | |
| Biotin-PEG-CH2CO2H, MW 1K-10K | Biotin-PEG-CH2CO2H, MW 1,000 is a carboxyl polyPEG used for biotinylation due to its strong binding with avidin/streptavidin. The carboxyl is reactive with amine in the presence of activating agent, such as HATU or EDC, to generate a covalent amide bond. Please contact us for GMP-grade inquiries. | |
| Fmoc-ACA-OH | Fmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates by Fmoc SPPS. Fmoc-ACA-OH must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled with HATU/collidine. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases. Treatment of the ACC peptide obtained after TFA cleavage with an aqueous base causes facile decarboxylation and formation of the AMC peptide. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-ACA-OH, 7-N-Fmoc-aminocoumarin-4-acetic acid. Product Category: Amino Acids. CAS No. 378247-75-7. Mole weight: 441.43. Product ID: ACM378247757. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Fmoc-N-Me-Cys(Trt)-OH | Building block for introduction of N-α-methyl-cysteine amino-acid residues by Fmoc SPPS. Fmoc SPPS of Cysteine-Containing Peptides. Uses: Fmoc-n-me-cys(trt)-oh is a fmoc-protected derivative of n-methyl cysteine used as a building block to prepare peptide thioesters under acidic conditions. the residue attached to the amino group of n-methylcysteine can migrate to the cysteinyl thiol group, resulting in the formation of a peptide thioester. the introduction of this fmoc-protected derivative is best achieved using hatu as a coupling reagent in the presence of dipea (n, n-diisopropylethylamine). it can also be used to prepare fmoc-n-me-cys(trt)-oallyl intermediate for the solid-phase synthesis of dithiol triostin a. Additional or Alternative Names: N-α-Fmoc-N-α-methyl-S-trityl-L-cysteine. Product Category: Amino Acids. CAS No. 944797-51-7. Mole weight: 599.74. Product ID: ACM944797517. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fmoc-TOAC-OH | Fmoc-TOAC-OH is a useful tool for the incorporation of the ESR spin-label TOAC into peptide sequences by Fmoc SPPS. Incorporation of this derivative and the following residue is best achieved using HATU activation. TFA/water/TIS should be used for cleavage of TOAC-containing peptides. The use of EDT should be avoided as it can cause permanent reduction of the nitroxide radical. Following cleavage, the TOAC peptide should be treated with aqueous ammonia in air to regenerate the nitroxide from the hydroxylamine that is generated by the TFA treatment. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-TOAC-OH, 2,2,6,6-Tetramethylpiperidine-N-oxyl-4-(9-fluorenylmethyloxycarbonyl-amino)-4-carboxylic acid. Product Category: Amino Acids. CAS No. 93372-25-9. Mole weight: 437.51. Product ID: ACM93372259-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| HDMA | Increased coupling efficiency and lower racemization compared to HATU. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 1- [ (Dimethylamino) (Morpholino) Methylene] -1H-[1,2,3]triazolo[4,5-b]pyridine-1-ium 3-oxide hexafluorophosphate. CAS No. 958029-37-3. Registered patent of Luxembourg Bio Technologies. | Luxembourg Bio Technologies |
| N-(acid-PEG3)-N-bis(PEG3-biotin) | N-(acid-PEG3)-N-bis(PEG3-biotin) is a branched biotin linker that can be used for protein labeling. The carboxylic acid group can react with primary amines in the presence of activators such as EDC and HATU. The hydrophilic PEG branch increases the water solubility of the compound. Please contact us for GMP-grade inquiries. Synonyms: N-(acid-PEG3)-N-bis(PEG3-biotin); BP-24425. Grade: 0.98. Molecular formula: C45H81N7O15S2. Mole weight: 1024.3. | |
| N-(Azido-PEG2)-N-Biotin-PEG3-acid | N-(Azido-PEG2)-N-Biotin-PEG3-acid is aclick chemistry biotinylation reagent. The azide group enables Click Chemistry. The terminal carboxylic acid can react with primary amino groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Grade: 98%. CAS No. 2112731-59-4. Molecular formula: C25H44N6O9S. Mole weight: 604.7. | |
| N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt | N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt is a branched biotinylation reagent for labeling. The carboxylic acid groups can react with primary amines in the presence of EDC and HATU to form stable amide bonds. Please contact us for GMP-grade inquiries. Grade: 0.98. CAS No. 2112731-49-2. Molecular formula: C42H78N4O18S. Mole weight: 959.2. | |
| PyOxim | PyOxim is a novel reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. It is has excellent solubility in DMF and is stable in solution under an inert atmosphere for two days. Unlike HATU and HBTU, it cannot cause chain terminating side reactions and is, therefore, ideal for the synthesis of cyclic peptides. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents. Synonyms: pyoxime; AS-10531; SC-13336; CS-0068035; K-4853; J-009012; (Ethyl cyano(hydroxyimino)acetato)-tri-(1-pyrrolidinyl)-phosphonium hexafluorophosphate; [cyano-(ethoxycarbonyl)methyleneaminooxy]tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)?-[ethyl 2-cyano-2-[(hydroxy-κO)?imino]?acetato]?tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(?1-). Grade: > 98% (HPLC). CAS No. 153433-21-7. Molecular formula: C17H29F6N5O3P2. Mole weight: 527.38. | |
| PyOxim® | Highly efficient coupling reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: [Ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinylphosphonium hexafluorophosphate. CAS No. 153433-21-7. | Luxembourg Bio Technologies |
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