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| Product | Description | |
|---|---|---|
| HBTU | HBTU is a coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-HBTU. CAS No. 94790-37-1. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-Y0912. |  |
| HBTU | HBTU is a coupling reagent used in peptide synthesis. HBTU has been shown to effectively suppress racemization. Group: Biochemicals. Alternative Names: 1-[Bis (dimethylamino) methylene]-1H-benzotriazolium Hexafluorophosphate(1-) 3-Oxide; N-HBTU. Grades: Highly Purified. CAS No. 94790-37-1. Pack Sizes: 10g. US Biological Life Sciences. |  Worldwide |
| HBTU | HBTU is coupling reagent for peptide synthesis. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: N-[(1H-benzotriazol-1-Yl) (Dimethylamino) Methylene] -N-methylmethanaminium hexaflourophosphate N-oxide. CAS No. 94790-37-1. |  Luxembourg Bio Technologies |
| HBTU (o-(Benzotriazol-1-yl)-N,N,N,N-tetramethyluronium hexafluorophosphate) | 100g Pack Size. Group: Biochemicals, Fluorinated Products, Peptide Reagents. Formula: C11H16F6N5OP. CAS No. 94790-37-1. Prepack ID 87448736-100g. Molecular Weight 379.24. See USA prepack pricing. |  |
| HBTU (o-(Benzotriazol-1-yl)-N,N,N,N-tetramethyluronium hexafluorophosphate) | 25g Pack Size. Group: Biochemicals, Fluorinated Products, Peptide Reagents. Formula: C11H16F6N5OP. CAS No. 94790-37-1. Prepack ID 87448736-25g. Molecular Weight 379.24. See USA prepack pricing. | |
| HBTU (o-(Benzotriazol-1-yl)-N,N,N,N-tetramethyluronium hexafluorophosphate) | 5g Pack Size. Group: Biochemicals, Fluorinated Products, Peptide Reagents. Formula: C11H16F6N5OP. CAS No. 94790-37-1. Prepack ID 87448736-5g. Molecular Weight 379.24. See USA prepack pricing. | |
| Fmoc-Cys(Trt)-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. The standard derivative for Fmoc SPPS of peptides containing Cys. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP, is to be employed, it is strongly recommended that collidine is used as the base , as this has been shown to significantly reduce loss of optical integrity during coupling. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Cys(Trt)-OH, N-α-Fmoc-S-trityl-L-cysteine. CAS No. 103213-32-7. Molecular formula: C37H31NO4S. Mole weight: 585.71. Catalog: ACM103213327-1. |  |
| Fmoc-Sec(pMeOBzl)-OH | Building block for the introduction of selenocysteine during Fmoc SPPS. Selenocysteine derivatives can undergo enantiomerization during coupling and can form dehydroalanine and β-piperidinylalanine containing side products during subsequent chain elongation. Therefore, activation methods, such as HBTU or PyBOP which involve the addition of a tertiary, base should be avoided for addition of the Sec and all subsequent residues. Cleavage and side-chain deprotection of Sec-containing peptides can be effected using tFA-m-cresol-thioanisole-EDT-water (80:5:5:5:5) or TFA-water-DCM-TIS (89:5:51) at 4 °C. As the Se-pMeOBzl bond is stable to TFA, these methods result in the formation of the corresponding Sev(pMeOBzl) peptide. Peptides containing two Sec(pMeOBzl) residues can be oxidized directly to the corresponding selenocystinyl peptides by treatment with 5-10% DMSO in TFA. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Sec(pMeOBzl)-OH, Fmoc-Sec(Mob)-OH, Fmoc-S-4-methoxybenzyl selenocysteine. CAS No. 150308-80-8. Molecular formula: C26H25NO5Se. Mole weight: 510.44. Catalog: ACM150308808. | |
| HATU | Similar to HBTU, but reacts faster with less epimerization during coupling. Nevertheless, HATU is preferred to HBTU in most rapid coupling protocols (while it is utilized in the same manner as HBTU). Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: 1- [Bis (Dimethylamino) Methylene] -1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate. CAS No. 148893-10-1. | Luxembourg Bio Technologies |
| HCTU | Aminium-based coupling reagent, analogous to HBTU, which in comparative studies was found to give superior results to TBTU in the synthesis of difficult peptides, in hindered couplings, and cyclizations. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(1H-6-Chlorobenzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9. | Luxembourg Bio Technologies |
| O-Benzotriazole-N,N,N',N'-tetramethyl-uronium-hexafluorophosphate | Peptide coupling reagent which suppresses racemization. Synonyms: HBTU; o-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium hexafluorophosphate; 2-(1h-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate; hbtu-reagent; MFCD00075445; N,N,N',N'-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate;[(benzotriazol-1-yloxy)-dimethylamino-methylene]-dimethyl-ammonium hexafluoro phosphate; O-(benzotriazol-1-yl)-N; SCHEMBL66487; KSC487E2N. Grades: ≥ 99% (HPLC). CAS No. 94790-37-1. Molecular formula: C11H16N5O.F6P. Mole weight: 379.24. |  |
| PyOxim | PyOxim is a novel reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. It is has excellent solubility in DMF and is stable in solution under an inert atmosphere for two days. Unlike HATU and HBTU, it cannot cause chain terminating side reactions and is, therefore, ideal for the synthesis of cyclic peptides. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents. Synonyms: pyoxime; AS-10531; SC-13336; CS-0068035; K-4853; J-009012; (Ethyl cyano(hydroxyimino)acetato)-tri-(1-pyrrolidinyl)-phosphonium hexafluorophosphate; [cyano- (ethoxycarbonyl) methyleneaminooxy]tris (1-pyrrolidinyl) phosphonium hexafluorophosphate; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)?-[ethyl 2-cyano-2-[(hydroxy-κO)?imino]?acetato]?tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(?1-). Grades: > 98% (HPLC). CAS No. 153433-21-7. Molecular formula: C17H29F6N5O3P2. Mole weight: 527.38. | |
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