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| Product | Description | |
|---|---|---|
| Hepcidin-2 | Hepcidin-2 is isolated from Mus musculus. It seems to act as a signaling molecule involved in the maintenance of iron homeostasis. |  |
| Hepcidin-22 (human) | Hepcidin-22 (human) is an inactive degradation product of Hepcidin-25 found in human urine. Synonyms: H-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys4-Cys10, Cys7-Cys20, Cys8-Cys19, Cys11-Cys16, air oxidized); L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-glycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinyl-glycyl-L-methionyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (4->10),(7->20),(8->19),(11->16)-tetrakis(disulfide). Grades: ≥95%. CAS No. 342790-22-1. Molecular formula: C99H151N29O25S9. Mole weight: 2436.06. | |
| Hepcidin-24 (human) | Hepcidin-24, an excellent substitute for biotinylated or heavy isotope-labeled hepcidin-25, is used as an internal reference in the determination of Hep-25 by mass spectrometry-based methods, for example in human serum or urine. Synonyms: H-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys6-Cys22, Cys9-Cys12, Cys10-Cys18, Cys13-Cys21, air oxidized); des-Asp1-Hepcidin-24. Grades: ≥95%. Molecular formula: C109H165N33O28S9. Mole weight: 2674.31. | |
| Hepcidin-25 (human) | Hepcidin-25 (hepatic bactericidal protein), also known as LEAP-1 (liver-expressed antimicrobial peptide), is found independently in human blood ultrafiltration and urine. It is mainly expressed in liver and belongs to a new family of small vertebrate antimicrobial peptides that contain 8 cysteine residues and has obvious antibacterial and antifungal activities. Hepcidin is the main human iron regulatory hormone, which can bind to iron exporter ferroportin and induce its internalization and degradation, thus blocking iron efflux from cells. Uses: Anti-infective agents. Synonyms: LEAP-1 (human); H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-His-Arg-Ser-Lys-Cys-Gly-Met-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys7-Cys23, Cys10-Cys13, Cys11-Cys19, Cys14-Cys22); L-alpha-aspartyl-L-threonyl-L-histidyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-glycyl-L-cysteinyl-L-cysteinyl-L-histidyl-L-arginyl-L-seryl-L-lysyl-L-cysteinyl-glycyl-L-methionyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (7->23),(10->13),(11->19),(14->22)-tetrakis(disulfide); Hepcidin Hepc25 (human); Hepcidin-25. Grades: ≥95% by HPLC. CAS No. 1356390-47-0. Molecular formula: C113H170N34O31S9. Mole weight: 2789.35. | |
| Hepcidin-1 (mouse) | Two kinds of hepcidin are found in mice. Hepcidin-1, a homolog of human Hepcidin-25 in serum, may be involved in murine brain iron metabolism. Hepcidin-2 is a pentapeptide with different sequences in urine. Synonyms: H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr-OH (Disulfide bridge: Cys7-Cys23, Cys10-Cys22, Cys11-Cys19, Cys13-Cys14); L-alpha-aspartyl-L-threonyl-L-asparagyl-L-phenylalanyl-L-prolyl-L-isoleucyl-L-cysteinyl-L-isoleucyl-L-phenylalanyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-cysteinyl-L-cysteinyl-L-asparagyl-L-asparagyl-L-seryl-L-glutaminyl-L-cysteinyl-glycyl-L-isoleucyl-L-cysteinyl-L-cysteinyl-L-lysyl-L-threonine (7->23),(10->22),(11->19),(13->14)-tetrakis(disulfide); L-α-Aspartyl-L-threonyl-L-asparaginyl-L-phenylalanyl-L-prolyl-N-[(1R, 4R, 7S, 10S, 13R, 18R, 21R, 24S, 30R, 33S, 36S, 39S, 42S, 45R, 50R, 53S)-53-(4-aminobutyl)-18-{[(2S)-6-amino-1-{[(1S, 2R)-1-carboxy-2-hydroxypropyl]amino}-1-oxo-2-hexanyl]carbamoyl}-39, 42-bis(2-amino-2-oxoethyl)-33-(3-amino-3-oxopropyl)-7-benzyl-10, 24-di[(2S)-2-butanyl]-36-(hydroxymethyl)-3, 6, 9, 12, 20, 23, 26, 29, 32, 35, 38, 41, 44, 52, 55, 60-hexadecaoxo-15, 16, 47, 48, 57, 58, 63, 64-octathia-2, 5, 8, 11, 19, 22, 25, 28, 31, 34, 37, 40, 43, 51, 54, 61-hexadecaazatetracyclo[28.25.4.44, 21.245, 50]pentahexacont-13-yl]-L-isoleucinamide. Grades: ≥95%. CAS No. 1676104-75-8. Molecular formula: C111H169N31O35S8. Mole weight: 2754.28. | |
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