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| Product | Description | |
|---|---|---|
| Herbimycin A | Herbimycin A, an ansamycin antibiotic , acts as a Src family kinase inhibitor. Herbimycin A binds to the SH domain and inhibits the activity of p60 v-src and p210 BCR-ABL Herbimycin A inhibits Hsp90 and impairs recovery from heat shock. Herbimycin A exhibits antiangiogenic activity in endothelial cells in vitro. Uses: Scientific research. Group: Natural products. CAS No. 70563-58-5. Pack Sizes: 1 mg; 2.5 mg; 500 μg; 100 μg. Product ID: HY-108486. |  |
| Herbimycin A | Herbimycin A is produced by the strain of Streptomyces hygroscopicus. It is an ansamycin antibiotic that acts as a Src family kinase inhibitor and Hsp90 inhibitor. It has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells. Uses: Enzyme inhibitors. Synonyms: Herbimycin; Antibiotic Tan 420F; NSC 305978. Grades: >98%. CAS No. 70563-58-5. Molecular formula: C30H42N2O9. Mole weight: 574.67. |  |
| Herbimycin A (Antibiotic TAN 420F, (15R)-17-Demethoxy-15-methoxy-11-O-methyl-geldanamycin) | Benzoquinone ansamycin antibiotic. Herbicidal compound. Potent, selective, irreversible and cell permeable protein tyrosine kinase inhibitor. Inhibitor of v-Src, Yes, Fps, Ros, Bcr-Abl and ErbB oncogene products. Antitumor compound. Antiangiogenic. Inhibits NF-kappaB activation and phosphorylation of phospholipase C-gamma1. Inhibitor of heat shock protein 90 (Hsp90). Binds Hsp90 and destabilizes client proteins leading to their ubiquitination and proteasomal degradation. Increases the sensitivity of certain cancer cells to chemotherapeutic agents. Neuroprotective. Antiparasitic, antischistosomal agent. Antiviral. Increase microtubules sensitivity to cold in plants. Group: Biochemicals. Grades: Highly Purified. CAS No. 70563-58-5. Pack Sizes: 100ug, 1mg. Molecular Formula: C30H42N2O9. US Biological Life Sciences. |  Worldwide |
| Herbimycin A, dihydro- (Antibiotic TAN 420E, Antibiotic NK 86-0084) | Antibiotic TAN 420E is the hydroquinone analogue of herbimycin A. It has been patented as an antibacterial, antifungal and antiprotozoan active. The study of Antibiotic TAN 402E has been over-shadowed by the more readily accessible quinone. Little is known of the selectively of the hydroquinone's biological profile compared to that of herbimycin A. Group: Biochemicals. Alternative Names: dihydro-Herbimycin A, Antibiotic NK 86-0084. Grades: Highly Purified. CAS No. 91700-93-5. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Herbimycin A from Streptomyces hygroscopicus | ≥95% (HPLC), powder. Uses: For analytical and research use. Group: Fluorescence/luminescence spectroscopy. CAS No. 70563-58-5. Pack Sizes: 0.1MG, 1MG. Mole Weight: 574.66. Catalog: AP70563585-A. Assay: ≥95% (HPLC). |  |
| Herbimycin A (Herbimycin, Antibiotic TAN 420F) | Herbimycin A is the major analogue of a complex of benzoquinone ansamycin antibiotics isolated from a Streptomyces hygroscopicus. Herbimycin A inhibits the 90-kD heat-shock protein (Hsp90) which provides essential chaperone support to various signal transduction molecules, including including certain steroid hormone receptors and select kinases. Herbimycin has also been shown to inhibit protein tyrosine kinase and angiogensis. Group: Biochemicals. Alternative Names: Herbimycin, Antibiotic TAN 420F. Grades: Highly Purified. CAS No. 70563-58-5. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Herbimycin B | It is produced by the strain of Streptomyces hygroscopicus. It is an ansamycin antibiotic that acts as a Src family kinase inhibitor. It has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells. Synonyms: Geldanamycin, 17-demethoxy-. Grades: ≥95%. CAS No. 76207-83-5. Molecular formula: C28H38N2O8. Mole weight: 530.61. | |
| Herbimycin C | It is produced by the strain of Streptomyces hygroscopicus. It is an ansamycin antibiotic that acts as a Src family kinase inhibitor. It has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells. Synonyms: Geldanamycin, 17-demethoxy-15-methoxy-, (15R)-. Grades: >98% by HPLC. CAS No. 91700-92-4. Molecular formula: C29H40N2O9. Mole weight: 560.64. | |
| Herbimycin C (Antibiotic TAN 420D) | Herbimycin C is a minor analogue of herbimycin complex isolated from Streptomyces hygroscopicus. Herbimycin C possesses potent antitumor activity and has been shown to convert Rous sarcoma virus-infected rat kidney cells into normal cells. Until now limited access has restricted a full investigation of the properties of herbimycin C. Research on related metabolites, herbimycin A and geldanamycin has stimulated intensive interest in this class as selective antitumor agents and for prolonging the viability of tissue-cultured cells and organs. Group: Biochemicals. Alternative Names: Antibiotic TAN 420D. Grades: Highly Purified. CAS No. 91700-92-4. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Herbimycin C, dihydro- (Antibiotic TAN 420C) | Antibiotic TAN 420C is a minor analogue of Herbimycin complex isolated from Streptomyces hygroscopicus. It is the hydroquinone of herbimycin C which is known to exhibit antitumor activity and has been shown to convert Rous sarcoma virus-infected rat kidney cells into normal cells. Group: Biochemicals. Alternative Names: Dihydro-herbimycin C. Grades: Highly Purified. CAS No. 91700-91-3. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Antibiotic tan 420c | Antibiotic tan 420c. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-ACETO-3-CHLORO-PROPYL ACETATE; HERBIMYCIN C, DIHYDRO- (ANTIBIOTIC TAN 420C); Antibiotic TAN 420C; ANTIBIOTIC TAN 420C; 2-Azabicyclo[16.3.1]docosane, geldanamycin deriv. Product Category: Heterocyclic Organic Compound. CAS No. 91700-91-3. Molecular formula: C29H42N2O9. Mole weight: 562.656. Purity: 0.96. IUPACName: Geldanamycin, 18,21-didehydro-17-demethoxy-18,21-dideoxo-18,21-dihydro. Density: 1.25±0.1 g/cm³ (20 °C, 760 mmHg). Product ID: ACM91700913. Alfa Chemistry ISO 9001:2015 Certified. Categories: TAN-420C. |  |
| TAN 420E | Antibiotic TAN 420E is a hydroquinone analogue of herbimycin A with antibacterial, antifungal and antiprotozoan activity. Synonyms: Dihydro-Herbimycin A; Dihydroherbimycin A. Grades: >95% by HPLC. CAS No. 91700-93-5. Molecular formula: C30H44N2O9. Mole weight: 576.68. | |
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