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1, 5-Cyclooctadiene (pyridine) (tri cyclohexylphosphine) iridium (I) Hexafluorophosphate is a catalyst that is used in the synthesis of 4α,5-Dihydro Simvastatin (D450010). 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. CAS No. 64536-78-3. Pack Sizes: 50mg, 100mg. Molecular Formula: C31H48F6IrNP2. US Biological Life Sciences.
Worldwide
1-Isopropyl-3-(4-fluorophenyl)indole-d7
1-Isopropyl-3-(4-fluorophenyl)indole-d7 is an isotope labelled derivative of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C17H9D7FN. US Biological Life Sciences.
2-(1,2-bis(4-fluorophenyl)-2-oxoethyl)-4-methyl-3-oxo-N-phenylpentanamide is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 4-Fluoro-β-(4-fluorophenyl)-α-(2-methyl-1-oxopropyl)-γ-oxo-N-phenylbenzenebutanamide. CAS No. 693793-82-7. Molecular formula: C26H23F2NO3. Mole weight: 435.46.
2-(2-(4-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 2-(2-(4-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxo-N-phenylpentanamide; 4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide. CAS No. 125971-96-2. Molecular formula: C26H24FNO3. Mole weight: 417.47.
2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenyl-Ethyl]-4-Methyl-3-Oxo-Pentanoic Acid, (2-Benzyloxy-Phenyl)-Amide-[d5]. Uses: A deuterated intermediate of the metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with. Synonyms: 4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-β-phenyl-N-[2-(phenylmethoxy)phenyl]benzenebutanamide-d5; 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-d5-ethyl]-4-methyl-3-oxo-pentanoic Acid, (2-Benzyloxy-phenyl)-amide. Grade: 95% atom D. CAS No. 1020719-43-0. Molecular formula: C33H25D5FNO4. Mole weight: 528.62.
2-[2-(4-Fluorophenyl)-2-Oxo-1-Phenyl-Ethyl]-4-Methyl-3-Oxo-Pentanoic Acid-[d5]. Uses: A deuterated intermediate of the metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with. Synonyms: 4-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-β-phenyl-N-[4-(phenylmethoxy)phenyl]benzenebutanamide-d5; 4-Methyl-3-oxo-N-(4-benzyloxyphenyl)-2-[1-phenyl-2-(4-fluorophenyl)-2-oxoethyl]pentamide-d5; 2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-d5-ethyl]-4-methyl-3-oxo-pentanoic Acid, (4-Benzyloxy-phenyl)-amide. Grade: 95% atom D. CAS No. 1020719-44-1. Molecular formula: C33H25D5FNO4. Mole weight: 528.62.
2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethylidene]-4-methyl-3-oxo-N-phenylpentanamide is an impurity of Atorvastatin (A791750) which is a selective, competitive HMG-CoA reductase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1331869-19-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C26H22FNO3, Molecular Weight: 415.46. US Biological Life Sciences.
Worldwide
2,2-Dibromo-1-(4-fluorophenyl)-2-phenylethanone
2,2-Dibromo-1-(4-fluorophenyl)-2-phenylethanone is an impurity/metabolite of Atorvastatin (A791730), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 100mg. Molecular Formula: C14H9Br2FO, Molecular Weight: 372.03. US Biological Life Sciences.
Worldwide
2,2-Dimethylbutanoyl Chloride
2,2-Dimethylbutanoyl chloride is a reagent that is used in the synthesis of 4α,5-Dihydro Simvastatin (D450010). 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. CAS No. 5856-77-9. Pack Sizes: 1g, 5g. Molecular Formula: C6H11ClO. US Biological Life Sciences.
Worldwide
2,3,4,5-Dianhydro Rosuvastatin Methyl Ester
2,3,4,5-Dianhydro Rosuvastatin Methyl Ester is an impurity of Rosuvastatin (R700500, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H26FN3O4S, Molecular Weight: 459.53. US Biological Life Sciences.
Worldwide
2,3-Anhydro Rosuvastatin Calcium Salt
2,3-Anhydro Rosuvastatin Calcium Salt is an impurity of Rosuvastatin (R700500, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: 2(C22H27FN3O5S-) Ca2+, Molecular Weight: 2464.534008. US Biological Life Sciences.
Worldwide
2,3-Anhydro Rosuvastatin Methyl Ester
2,3-Anhydro Rosuvastatin Methyl Ester is an impurity of Rosuvastatin (R700500, Ca Salt); a selective, competitive HMG-CoA reductase inhibitor and antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H28FN3O5S, Molecular Weight: 477.55. US Biological Life Sciences.
2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid is an intermediate useful in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1391194-36-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C33H33FN2O5, Molecular Weight: 556.62. US Biological Life Sciences.
2-(4-Fluorophenyl)-δ-hydroxy-5-(1-methylethyl)- β -oxo-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of rac-3-Oxo Atorvastatin Sodium Salt (O847150), which is a byproduct impurity of Atorvastatin Calcium (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 947262-20-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C37H41FN2O5, Molecular Weight: 612.73. US Biological Life Sciences.
2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C32H37NO4. Mole weight: 499.64.
2-((4S,6S)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. CAS No. 2165770-84-1. Molecular formula: C10H19NO4. Mole weight: 217.27.
2-Amino-2'-fluorobenzophenone
An intermediate in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Synonyms: 2-Amino-2'-fluoro-benzophenone; (2-Amino-phenyl)-(2-fluoro-phenyl)-methanone. Grade: ≥ 95%. CAS No. 1581-13-1. Molecular formula: C13H10FNO. Mole weight: 215.22.
2-Amino-4'-fluorobenzophenone
2-Amino-4'-fluorobenzophenone is an intermediate in the preparation of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Uses: An intermediate in the preparation of the anticholesteremic pitavastatin. Synonyms: 2-Aminophenyl 4-Fluorophenyl Ketone; o-(p-Fluorobenzoyl)aniline; (2-Amino-4'-fluoro-phenyl)-phenyl-methanone; 2-Amino-4'-fluorobenzophenone. Grade: ≥95%. CAS No. 3800-6-4. Molecular formula: C13H10FNO. Mole weight: 215.22.
2-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester-[d5] is the labelled analogue of 2-Benzyloxy Atorvastatin Acetonide tert-Butyl Ester, which is a metabolite of Atorvastatin. Uses: A deuterated intermediate of the metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with. Synonyms: 2-Benzyloxy Atorvastatin-d5 Acetonide tert-Butyl Ester. Grade: 98% atom D. CAS No. 265989-41-1. Molecular formula: C47H48D5FN2O6. Mole weight: 765.96.
[ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium-d5 Bromide is the isotope labelled analog of [ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium Bromide which is used to prepare artificial HMG-CoA reductase inhibitors. It is also used in the synthesis of pitavastatin calcium. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C37H25D5BrFNP, Molecular Weight: 623.549999999999. US Biological Life Sciences.
[[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenyl-phosphonium Bromide is an impurity in the production of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: Pitavastatin Impurity 44 Bromide; Phosphonium, [[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenyl-, bromide (1:1). Grade: ≥95%. CAS No. 154057-58-6. Molecular formula: C37H30BrFNP. Mole weight: 618.52.
2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol is one of Pitavastatin intermediates. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Uses: Pitavastatin intermediate. Synonyms: 2-Cyclopropyl-4-(4'-fluorophenyl)Quinolyl-3-methanol; Pitavastatin Impurity 31. Grade: ≥95%. CAS No. 121660-11-5. Molecular formula: C19H16FNO. Mole weight: 293.33.
2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Methyl 2-cyclopropyl-4-phenylquinoline-3-carboxylate; 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester; DTXSID00857071; AKOS022175172; SB72967; Methyl2-cyclopropyl-4-phenylquinoline-3-carboxylate. CAS No. 868536-53-2. Molecular formula: C20H17NO2. Mole weight: 303.35.
(2-Cyclopropyl-4-phenylquinolin-3-yl)methanol
(2-Cyclopropyl-4-phenylquinolin-3-yl)methanol is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (2-CYCLOPROPYL-4-PHENYLQUINOLIN-3-YL)METHANOL; MFCD28384714; SY320331; (2-Cyclopropyl-4-phenyl-3-quinolyl)methanol; F86792. Molecular formula: C19H17NO. Mole weight: 275.34.
2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde
2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: 2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde; 2153433-59-9. Grade: 98%. CAS No. 2153433-59-9. Molecular formula: C19H15NO. Mole weight: 273.33.
2'-Ethyl Simvastatin
2'-Ethyl Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. CAS No. 79902-42-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H34O5, Molecular Weight: 390.51. US Biological Life Sciences.
Worldwide
2'-Ethyl Simvastatin-d6
Isotope labelled 2'-Ethyl Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H28D6O5, Molecular Weight: 396.55. US Biological Life Sciences.
Worldwide
2-Fluoro Atorvastatin tert-Butyl Ester
2-Fluoro Atorvastatin tert-Butyl Ester is an impurity formed in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1099474-28-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C40H47FN2O5. US Biological Life Sciences.
Worldwide
2-Fluoro Atorvastatin tert-Butyl Ester
2-Fluoro Atorvastatin tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6R)-6-(2-(2-(2-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6R)-6-[2-[2-(2-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. CAS No. 1099474-28-8. Molecular formula: C40H47FN2O5. Mole weight: 654.81.
2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester-[d5] is the labelled analogue of 2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester, which is a metabolite of Atorvastatin. Uses: A deuterated intermediate of the metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with. Synonyms: 2-Hydroxy Atorvastatin-D5 Acetonide tert-Butyl Ester. Grade: 95% atom D. CAS No. 265989-42-2. Molecular formula: C40H42D5FN2O6. Mole weight: 675.84.
2-Hydroxy Atorvastatin Lactone-[d5]
2-Hydroxy Atorvastatin Lactone-[d5] is the labelled analogue of 2-Hydroxy Atorvastatin Lactone, which is a metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Uses: An isotopically labelled metabolite of atorvastin, a selective, competitive hmg-coa reductase inhibitor. atorvastin is the only drug in its class specfically indicated for lowering both elevated ldl-cholesterol and triglycerides in patients with hypercho. Synonyms: 2-Hydroxy Atorvastatin Lactone D5; 5-(4-Fluorophenyl)-N-(2-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide-d5; O-Hydroxy atorvastatin lactone-d5. Grade: ≥95%; ≥98% atom D. CAS No. 265989-50-2. Molecular formula: C33H28D5FN2O5. Mole weight: 561.65.
2-Hydroxy Atorvastatin tert-Butyl Ester-d5
2-Hydroxy Atorvastatin tert-Butyl Ester-d5 is an intermediate in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C37H38D5FN2O6, Molecular Weight: 635.78. US Biological Life Sciences.
Worldwide
2-Methyl Simvastatin (Mixture Of Diasteroisomers)
2-Methyl Simvastatin is an impurity of Simvastatin, a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Grades: Highly Purified. CAS No. 774611-54-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C26H40O5. US Biological Life Sciences.
Worldwide
3,4-Epoxy-6-keto-4a,5-ene Simvastatin
3,4-Epoxy-6-keto-4A,6-ene Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus and a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
3-(4-Fluorophenyl)-1H-indole
3-(4-Fluorophenyl)-1H-indole is a reagent used in the synthesis indole based sigma receptor ligands. Also used in the preparation of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Grades: Highly Purified. CAS No. 101125-32-0. Pack Sizes: 2.5g, 5g. Molecular Formula: C14H10FN. US Biological Life Sciences.
Worldwide
3',5'-Dihydrodiol Simvastatin (Mixture of Diastereomers)
A metabolite of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 3',5'-Dihydrodiol Simvastatin(Mixture of Diastereomers). CAS No. 198818-02-9. Molecular formula: C25H40O7. Mole weight: 452.58.
3-a-Hydroxy Pravastatin Sodium Salt (3-a-iso-Pravastatin)
A metabolite of Pravastatin, a competitive inhibitor of HMG-CoA reductase. Bioactive metabolite of mevastatin. Group: Biochemicals. Alternative Names: 3-a-iso-Pravastatin. Grades: Highly Purified. CAS No. 81093-43-8. Pack Sizes: 1mg. US Biological Life Sciences.
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline is used to prepare artificial HMG-CoA reductase inhibitors. It is also used to synthesize pitavastatin calcium via stereoselective Wittig olefination reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 154057-56-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C19H15BrFN. US Biological Life Sciences.
Worldwide
3-Hydroxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?7,?8,?8a-hexahydro-3-hydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester. Grade: > 95%. CAS No. 134523-09-4. Molecular formula: C25H38O6. Mole weight: 434.57.
3-Hydroxy Simvastatin Acid, Sodium Salt
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 3"-Hydroxy Simvastatin Acid Sodium Salt; 3-Hydroxy Simvastatin Acid, Sodium Salt. Grade: > 95%. Molecular formula: C25H39O7 Na. Mole weight: 451.59 22.99.
3-Methylene Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol in the liver. Synonyms: 3-Butenoic acid, 2,2,3-trimethyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α,3α,7β,8β(2S*,4S*),8aβ]]-; [1S-[1α,3α,7β,8β(2S*,4S*),8aβ]]-2,2,3-Trimethyl-3-butenoic Acid 1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester; 3-Methylene Simvastatin Impurity; Simvastatin-3-en; (1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2,3-trimethylbut-3-enoate. Grade: ≥95%. CAS No. 79902-62-8. Molecular formula: C26H38O5. Mole weight: 430.58.
3-O-Ethyl Rosuvastatin
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Grade: > 95%. Molecular formula: C24H32FN3O6S. Mole weight: 509.6.
3-Oxo Rosuvastatin Sodium Salt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: 3-Oxo Rosuvastatin SodiuM Salt; -7-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(Methylsulfonyl)aMino]-5-pyriMidinyl]-5-hydroxy-3-oxo-. Grade: > 95%. CAS No. 1346606-28-7. Molecular formula: C22H25FN3O6S. Na. Mole weight: 501.51.
(3R,5R)-Fluvastatin Sodium Salt
3R,5R)-Fluvastatin Sodium Salt is a prominent compound in the biomedical industry, aiding in the research of hypercholesterolemia. As a member of the esteemed statin class, it exerts its action by effectively inhibiting the pivotal enzyme HMG-CoA reductase. This paramount compound is frequently recommended to ameliorate LDL cholesterol levels. Grade: > 95%. Molecular formula: C24H25FNO4Na. Mole weight: 433.46.
(3R,5R)-Rosuvastatin Methyl Ester
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester. Grade: > 95%. CAS No. 1776088-23-3. Molecular formula: C23H30FN3O6S. Mole weight: 495.57.
(3R,5R)-Rosuvastatin Sodium Salt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3R,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium. Grade: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
(3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt
(3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-7,8-dihydro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid Sodium Salt. Molecular formula: C25H23FNNaO4. Mole weight: 443.44.
(3R,5S)-6-Chloro-3,5-dihydroxyhexanoic Acid tert-Butyl Ester is an intermediate in the synthesis of Rosuvastatin (R700500), a selective, competitive HMG-CoA reductase inhibitor. Group: Biochemicals. Alternative Names: (3R,5S)-6-Chloro-3,5-dihydroxy-,Hexanoic Acid 1,1-dimethylethyl Ester. Grades: Highly Purified. CAS No. 154026-93-4. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt
(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Defluoro Pitavastatin. Molecular formula: C25H24NNaO4. Mole weight: 425.45.
(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester is an intermediate in the synthesis of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (3R,5S,E)-Tert-butyl 7-(2-cyclopropyl-4-phenylquinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Pitavastatin Impurity compound C; 2-Methyl-2-propanyl (3R,5S,6E)-7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoate; 6-Heptenoic acid, 7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-. Grade: 97%. Molecular formula: C29H33NO4. Mole weight: 459.58.
(3R,5S)-Atorvastatin Acetonide tert-Butyl Ester
(3R,5S)-Atorvastatin Acetonide tert-Butyl Ester is the impuritiy of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Synonyms: tert-butyl 2-((4R,6S)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; (4R,6S)-6-[2-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl 1,3-Dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl (4R,6S)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate. CAS No. 947249-30-1. Molecular formula: C40H47FN2O5. Mole weight: 654.81.
(+)-3R,5S-Fluvastatin-d6 sodium salt
One of the isotopic labelled isomers of Fluvastatin, which is a HMG-CoA reductase inhibitor and could be used as an antilipemic agent. Synonyms: (+)-(3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt-d6. Molecular formula: C24H19FNO4D6.Na. Mole weight: 439.60.
(3R,5S)-Fluvastatin sodium
(3R,5S)-Fluvastatin ((3R,5S)-XU 62-320) sodium is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (3R,5S)-XU 62-320. CAS No. 94061-80-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14664F.
A synthetic HMG-CoA reductase inhibitor. Antilipemic. Group: Biochemicals. Alternative Names: (3R,5S)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. Grades: Highly Purified. CAS No. 94061-80-0. Pack Sizes: 1mg. Molecular Formula: C24H25FNNaO4, Molecular Weight: 433.45. US Biological Life Sciences.
Worldwide
(3R)-Hydroxperoxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3R,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grade: > 95%. CAS No. 1092716-42-1. Molecular formula: C25H38O7. Mole weight: 450.57.
An impurity of Pitavastatin, an HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increases HDL cholesterol in the blood. Synonyms: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, (3S,5R,6E)-; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid; (3S,5R,E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid. Grade: 95%. CAS No. 254452-86-3. Molecular formula: C25H24FNO4. Mole weight: 421.46.
(3S,5R)-Fluvastatin-[d6] sodium
(3S,5R)-Fluvastatin-[d6] sodium is the labelled isomer of Fluvastatin, which is a HMG-CoA reductase inhibitor and could be used as an antilipemic agent. Synonyms: (3S,5R)-Fluvastatin D6 sodium; (-)-(3S,5R)-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid-d6 Sodium Salt; (-)-3S,5R-Fluvastatin-d6 sodium salt; [R-[R*,S*-(E)]]-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid-d6 Monosodium Salt; ent-Fluvastatin-d6 Sodium Salt. Grade: 98%. CAS No. 2249799-35-5. Molecular formula: C24H19D6FNNaO4. Mole weight: 439.48.
(3S,5R)-Pitavastatin Calcium
A metabolite of Pitavastatin which is a potent inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Synonyms: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grade: > 95%. CAS No. 254452-88-5. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.86.
(3S,5R)-Rosuvastatin Methyl Ester
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Synonyms: (3S,5R)-Rosuvastatin Methyl Ester. Grade: > 95%. CAS No. 1112048-62-0. Molecular formula: C23H30FN3O6S. Mole weight: 495.57.
(3S,5R)-Rosuvastatin Sodium Salt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Grade: > 95%. Molecular formula: C22H27FN3O6S. Na. Mole weight: 503.53.
(3S,5S)-Atorvastatin sodium salt
Atorvastatin is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective against hypercholesterolemia and certain dyslipidemias. Synonyms: 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid, monosodium salt; 3S,5S-Atorvastatin Sodium; sodium (3S,5S)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate. Grade: ≥98%. CAS No. 1428118-38-0. Molecular formula: C33H34FN2O5·Na. Mole weight: 580.6.
(3S,5S)-Atorvastatin Sodium Salt
A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. Group: Biochemicals. Alternative Names: ( βS,δS)-2-(4-Fluorophenyl)- β , δ -dihydroxy-5- (1-methylethyl)-3-phenyl-4-[ (phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium; 3S,5S-Atorvastatin Sodium. Grades: Highly Purified. CAS No. 501121-34-2. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C33H34FN2NaO5, Molecular Weight: 580.62. US Biological Life Sciences.
Worldwide
(3S, 5S)-Dihydroxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?4,?6,?7,?8,?8a-octahydro-4,?6-dihydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester, [1S-[1α,?3α,?4β,?6α,?7β,?8β(2S*,?4S*)?,?8aβ]?]?- (9CI). Grade: > 95%. CAS No. 159143-77-8. Molecular formula: C25H40O7. Mole weight: 452.58.
(3S,5S) Rosuvastatin Calcium Salt
An impurity of Rosuvastatin.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Grade: > 95%. Molecular formula: C44H54F2N6O12S2. Ca. Mole weight: 1001.16.
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