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| Product | Description | |
|---|---|---|
| hormone-sensitive lipase | This enzyme is a serine hydrolase. Compared with other lipases, hormone-sensitive lipase has a uniquely broad substrate specificity. It hydrolyses all acylglycerols (triacylglycerol, diacylglycerol and monoacylglycerol) as well as cholesteryl esters, steroid fatty acid esters, retinyl esters and p-nitrophenyl esters. It exhibits a preference for the 1- or 3-ester bond of its acylglycerol substrate compared with the 2-ester bond. The enzyme shows little preference for the fatty acids in the triacylglycerol, although there is some increase in activity with decreasing chain length. The enzyme activity is increased in response to hormones that elevate intracellular levels of cAMP. Group: Enzymes. Synonyms: HSL. Enzyme Commission Number: EC 3.1.1.79. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3507; hormone-sensitive lipase; EC 3.1.1.79; HSL. Cat No: EXWM-3507. |  |
| 2-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic Acid Ethyl Ester | A boronic acid ester derivative as inhibitor of hormone-sensitive lipase. Group: Biochemicals. Grades: Highly Purified. CAS No. 346656-34-6. Pack Sizes: 1g. US Biological Life Sciences. |  Worldwide |
| Cyclipostin A | It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 20 nmol/L against HSL in rats. Molecular formula: C23H41O7P. Mole weight: 460.54. |  |
| Cyclipostin P | It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 30 nmol/L against HSL in rats. Synonyms: (1beta)-4beta-(Hexadecyloxy)-6-methyl-8-oxo-3,5,9-trioxa-4-phosphabicyclo[5.3.0]deca-6-ene 4-oxide; (6S)-6alpha-(Hexadecyloxy)-8-methyl-3,3abeta-dihydro-1H,4H,6H-2,5,7-trioxa-6-phosphaazulene-1-one 6-oxide. Molecular formula: C23H41O6P. Mole weight: 444.54. | |
| Cyclipostin P2 | It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 40 nmol/L against HSL in rats. Molecular formula: C23H41O6P. Mole weight: 444.54. | |
| Cyclipostin S | It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 20 nmol/L against HSL in rats. Molecular formula: C24H43O6P. Mole weight: 458.57. | |
| [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase | The enzyme is activated by AMP. EC 1.1.1.34, hydroxymethylglutaryl-CoA reductase (NADPH) is inactivated by the phosphorylation of the enzyme protein. Histones can also act as acceptors. The enzyme can also phosphorylate hepatic acetyl-CoA carboxylase (EC 6.4.1.2) and adipose hormone-sensitive lipase (EC 3.1.1.79). Thr-172 within the catalytic subunit (α-subunit) is the major site phosphorylated by the AMP-activated protein kinase kinase. GTP can act instead of ATP. Group: Enzymes. Synonyms: AMPK; AMP-activated protein kinase; HMG-CoA reductase kinase; β-hydro. Enzyme Commission Number: EC 2.7.11.31. CAS No. 172522-01-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3152; [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase; EC 2.7.11.31; 172522-01-9; AMPK; AMP-activated protein kinase; HMG-CoA reductase kinase; β-hydroxy-β-methylglutaryl-CoA reductase kinase; [hydroxymethylglutaryl-CoA reductase (NADPH2)] kinase; 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase; 3-hydroxy-3-methylglutaryl-CoA reductase kinase; hydroxymethylglutaryl coenzyme A reductase kinase; hydroxymethylglutaryl coenzyme A reductase kinase (phosphorylating); hydroxymethylglutaryl-CoA reductase kinase; reductase kinase; STK29. Cat No: EXWM-3152. | |
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