Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| hydroperoxide dehydratase | Acts on a number of unsaturated fatty-acid hydroperoxides, forming the corresponding allene oxides. The product of the above reaction is unstable and is acted upon by EC 5.3.99.6, allene-oxide cyclase, to form the cyclopentenone derivative (15Z)-12-oxophyto-10,15-dienoate (OPDA), which is the first cyclic and biologically active metabolite in the jasmonate biosynthesis pathway. The enzyme from many plants belongs to the CYP-74 family of P-450 monooxygenases. Group: Enzymes. Synonyms: hydroperoxide isomerase; linoleate hydroperoxide isomerase; linoleic acid hydroperoxide isomerase; HPI; (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase; (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-fo. Enzyme Commission Number: EC 4.2.1.92. AOS. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5076; hydroperoxide dehydratase; EC 4.2.1.92; hydroperoxide isomerase; linoleate hydroperoxide isomerase; linoleic acid hydroperoxide isomerase; HPI; (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase; (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]; allene oxide synthase; AOS. Cat No: EXWM-5076. |  |
| 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase | The enzyme contains heme. The bifunctional enzyme from Aspergillus nidulans uses different heme domains to catalyse two separate reactions. Linoleic acid is oxidized within the N-terminal heme peroxidase domain to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate (cf. EC 1.13.11.60, linoleate 8R-lipoxygenase), which is subsequently isomerized to (5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate within the C-terminal P-450 heme thiolate domain. Group: Enzymes. Synonyms: 5,8-LDS (bifunctional enzyme); 5,8-linoleate diol synthase (bifunctional enzyme); 8-hydroperoxide isomerase; (8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((5S,8R,9Z,12Z)-5,8-dihydroxy-9,12-octadecadienoate-forming); PpoA. Enzyme Commission Number: EC 5.4.4.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5546; 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase; EC 5.4.4.5; 5,8-LDS (bifunctional enzyme); 5,8-linoleate diol synthase (bifunctional enzyme); 8-hydroperoxide isomerase; (8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((5S,8R,9Z,12Z)-5,8-dihydroxy-9,12-octadecadienoate-forming); PpoA. Cat No: EXWM-5546. | |
| 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase | The enzyme contains heme. The bifunctional enzyme from Gaeumannomyces graminis catalyses the oxidation of linoleic acid to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate (cf. EC 1.13.11.60, linoleate 8R-lipoxygenase), which is then isomerized to (7S,8S,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate. Group: Enzymes. Synonyms: 8-hydroperoxide isomerase (ambiguous); (8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-7,8-dihydroxy-9,12-octadecadienoate-forming). Enzyme Commission Number: EC 5.4.4.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5547; 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase; EC 5.4.4.6; 8-hydroperoxide isomerase (ambiguous); (8R,9Z,12Z)-8-hydroperoxy-9,12-octadecadienoate mutase ((7S,8S,9Z,12Z)-7,8-dihydroxy-9,12-octadecadienoate-forming). Cat No: EXWM-5547. | |
| phospholipid-hydroperoxide glutathione peroxidase | A protein containing a selenocysteine residue. The products of action of EC 1.13.11.12 lipoxygenase on phospholipids can act as acceptors; H2O2 can also act, but much more slowly (cf. EC 1.11.1.9 glutathione peroxidase). Group: Enzymes. Synonyms: peroxidation-inhibiting protein; PHGPX; peroxidation-inhibiting protein:peroxidase,glutathione (phospholipid hydroperoxide-reducing); phospholipid hydroperoxide glutathione peroxidase; hydroperoxide glutathione peroxidase. Enzyme Commission Number: EC 1.11.1.12. CAS No. 97089-70-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0493; phospholipid-hydroperoxide glutathione peroxidase; EC 1.11.1.12; 97089-70-8; peroxidation-inhibiting protein; PHGPX; peroxidation-inhibiting protein:peroxidase,glutathione (phospholipid hydroperoxide-reducing); phospholipid hydroperoxide glutathione peroxidase; hydroperoxide glutathione peroxidase. Cat No: EXWM-0493. | |
| Ritonavir Impurity G (Hydroperoxide Impurity) | An impurity of Ritonavir.Ritonavir is a selective HIV protease inhibitor. Synonyms: Thiazol-5-ylmethyl ((2S,3S,5S)-5-((S)-2-(3-((2-(2-hydroperoxypropan-2-yl)thiazol-4-yl)methyl)-3-methylureido)-3-methylbutanamido)-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate ; (Hydroperoxide Impurity). Grades: > 95%. Molecular formula: C37H48N6O7S2. Mole weight: 752.96. |  |
| Tert-Butyl-Hydroperoxide (TBHP) | Tert-Butyl-Hydroperoxide (TBHP). CAS No. 75-91-2. Molecular formula: C4H10O2. |  |
| trans-5-Phenyl-4-pentenyl hydroperoxide | ?90%, Solution in ethanol. Group: Fluorescence/luminescence spectroscopy. |  |
| 1-Iodoheptane | 1-Iodoheptane acts as a reagent in the preparation of glycosyl hydroperoxide, a potential antimalarial agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 4282-40-0. Pack Sizes: 250mg, 1g. Molecular Formula: C7H15I, Molecular Weight: 226.1. US Biological Life Sciences. |  Worldwide |
| 3-Chloroperbenzoic Acid (70-75%, wet with water) | 3-Chloroperbenzoic Acid (70-75%, wet with water). Group: Biochemicals. Alternative Names: 3-Chloro Benzene carboperoxoic Acid; m-Chloroperoxybenzoic Acid; 3-Chloro Benzene carboperoxoic acid; 3-Chloroperbenzoic acid; 3-Chloroperoxybenzoic Acid; MCPBA; NSC 97094; m-Chlorobenzoyl Hydroperoxide; m-Chloroperbenzoic Acid; m-Chloroperoxobenzoic Acid; m-Chloroperoxybenzoic Acid; m-Chloroperoxybenzoic Acid. Grades: Highly Purified. CAS No. 937-14-4. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| 4-hydroperoxycyclophosp hamide (4-HC) | A metabolite of Cyclophosphamide. Antineoplastic; bone marrow purging agent. Group: Biochemicals. Alternative Names: 2-[Bis (2-chloroethyl) amino]tetrahydro-2-oxido-2H-1, 3, 2-oxazaphosphorin-4-yl Hydroperoxide; 4-hydroperoxycyclofosfa mide ; Asta 6496. Grades: Highly Purified. CAS No. 39800-16-3. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C7H15Cl2N2O4P, Molecular Weight: 293.08. US Biological Life Sciences. | Worldwide |
| 9(S)-HpODE | 9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid. Uses: Scientific research. Group: Natural products. Alternative Names: 9-D-Hydroperoxylinoleic acid. CAS No. 29774-12-7. Pack Sizes: 50 μg (1.60 mM * 100 μL in Ethanol). Product ID: HY-118149. |  |
| allene-oxide cyclase | Allene oxides formed by the action of EC 4.2.1.92 hydroperoxide dehydratase, are converted into cyclopentenone derivatives. Group: Enzymes. Enzyme Commission Number: EC 5.3.99.6. CAS No. 118390-59-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5514; allene-oxide cyclase; EC 5.3.99.6; 118390-59-3. Cat No: EXWM-5514. | |
| Allene Oxide Synthase from Parthenium argentatum, Recombinant | Potent anti-oxidant enzyme to remove lipid hydroperoxides in biological samples. Allene oxide synthase converts lipoxygenase derived fatty acid hydroperoxides to unstable allene epoxides. In plants, allene oxide is a precursor of jasmonic acid, which is important for growth regulation. Applications: Allene oxide synthase is a potent anti-oxidant enzyme used to remove lipid hydroperoxides in various biological samples. it may also be used to study stress induced gene expression in plants. Group: Enzymes. Synonyms: hydroperoxide isomerase; linoleate hydroperoxide isomerase; linoleic acid hydroperoxide isomerase; HPI; (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydr. Enzyme Commission Number: EC 4.2.1.92. AOS. Activity: 25,000-40,000 units/mg protein. Storage: Store at -20°C. Form: Supplied as a solution in phosphate buffered sale pH 7.2. Source: E. coli. Species: Parthenium argentatum. hydroperoxide isomerase; linoleate hydroperoxide isomerase; linoleic acid hydroperoxide isomerase; HPI; (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase; (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate 12,13-hydro-lyase [(9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate-forming]; allene oxide synthase; AOS; EC 4.2.1.92; hydroperoxide dehydratase. Pack: vial of ~300 μg. Cat No: NATE-0808. | |
| Bis-(1-octyloxy-2,2,6,6-tetramethyl-4-piperidinyl)sebacate | Bis-(1-octyloxy-2,2,6,6-tetramethyl-4-piperidinyl)sebacate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: decanedioicacid,bis(2,2,6,6-tetramethyl-4-piperidinyl)ester,reactionproduc;tswithtert-buhydroperoxideandoctane;TINUVIN 123;DECANEDIOIC ACID, BIS(2,2,6,6-TETRAMETHYL-4-PIPERIDINYL)ESTER, REACTION PRODUCTS WITH 1,1-DIMETHYLETHYL-HYDROPEROXIDE AND OCTANE;BIS. Product Category: Polymer/Macromolecule. CAS No. 129757-67-1. Molecular formula: C44H84N2O6. Mole weight: 737.15. Product ID: ACM129757671. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bis(2,2,6,6-tetramethyl-1-(octyloxy)piperidin-4-yl) decanedioate. |  |
| colneleate synthase | A heme-thiolate protein (P-450). It catalyses the selective removal of pro-R hydrogen at C-8 in the biosynthesis of colneleic acid. It forms also (8E)-9-[(1E,3Z,6Z)-nona-1,3,6-trien-1-yloxy]non-8-enoic acid (i.e. colnelenate) from (9S,10E,12Z,15Z)-9-hydroperoxy-10,12,15-octadecatrienoate. The corresponding 13-hydroperoxides are poor substrates. The divinyl ethers colneleate and colnelenate have antimicrobial activity. Group: Enzymes. Synonyms: 9-divinyl ether synthase; 9-DES; CYP74D; CYP74D1; CYP74 cytochrome P-450; DES1; (8E)-9-[(1E,3E)-nona-1,3-dien-1-yloxy]non-8-enoate synthase. Enzyme Commission Number: EC 4.2.1.121. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4962; colneleate synthase; EC 4.2.1.121; 9-divinyl ether synthase; 9-DES; CYP74D; CYP74D1; CYP74 cytochrome P-450; DES1; (8E)-9-[(1E,3E)-nona-1,3-dien-1-yloxy]non-8-enoate synthase. Cat No: EXWM-4962. | |
| (E)-4-Oxo-2-nonenal | (E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-ONE. CAS No. 103560-62-9. Pack Sizes: 5 mg; 500 μg. Product ID: HY-114524. | |
| Ganodermanondiol | Ganodermanondiol is a melanogenesis inhibitor isolated from the Ganoderma lucidum.Ganodermanondiol exhibits potent cytoprotective effects on tert-butyl hydroperoxide-induced hepatotoxicity. Ganodermanondiol shows significant anti-HIV-1 protease activity with an IC50 of 90 μM. Ganodermanondiol exhibits a strong anticomplement activity against the classical pathway of the complement system with an IC50 of 41.7μM. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 107900-76-5. Molecular formula: C30H48O3. Mole weight: 456.7. Purity: 0.98. IUPACName: (5R,10S,13R,14R,17R)-17-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one. Canonical SMILES: CC(CCC(C(C)(C)O)O)C1CCC2(C1(CC=C3C2=CCC4C3(CCC(=O)C4(C)C)C)C)C. Product ID: ACM107900765-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ganodermanontriol | Ganodermanontriol, a sterol isolated from Ganoderma lucidum , induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 106518-63-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N1506. | |
| glutathione amide-dependent peroxidase | This enzyme, which has been characterized from the proteobacterium Marichromatium gracile, is a chimeric protein, containing a peroxiredoxin-like N-terminus and a glutaredoxin-like C terminus. The enzyme has peroxidase activity towards hydrogen peroxide and several small alkyl hydroperoxides, and is thought to represent an early adaptation for fighting oxidative stress. The glutathione amide disulfide produced by this enzyme can be restored to glutathione amide by EC 1.8.1.16 (glutathione amide reductase). Group: Enzymes. Enzyme Commission Number: EC 1.11.1.17. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0498; glutathione amide-dependent peroxidase; EC 1.11.1.17. Cat No: EXWM-0498. | |
| Glutathione Oxidized (GSSG, Glutathione Oxidase, Glutathiol, Glutathione Disulfide) | Glutathione is a tripeptide with applications in many metabolic areas, such as hydroperoxide removal, anti-ionization protection and reaction with and detoxification of cellular functions. Group: Biochemicals. Alternative Names: Glutathione disulfide; N, N'- [Dithiobis [1- [ (carboxymethyl) carbamoyl] ethylene] ] diglutamine; GSSG; Glutathione Disulphide; Glutathione-S-S-glutathione; Glutathione-SSG; Glutathone Disulfide; Oxidized L-Glutathione; Oxidized Glutathione; Oxiglutatione. Grades: Molecular Biology Grade. CAS No. 27025-41-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| glutathione peroxidase | A protein containing a selenocysteine residue. Steroid and lipid hydroperoxides, but not the product of reaction of EC 1.13.11.12 lipoxygenase on phospholipids, can act as acceptor, but more slowly than H2O2 (cf. EC 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase). Group: Enzymes. Synonyms: GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase. Enzyme Commission Number: EC 1.11.1.9. CAS No. 9013-66-5. GSH-Px. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0511; glutathione peroxidase; EC 1.11.1.9; 9013-66-5; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase. Cat No: EXWM-0511. | |
| hydroperoxy fatty acid reductase | The enzyme, characterized from the cyanobacterium Synechocystis PCC 6803, can reduce unsaturated fatty acid hydroperoxides and alkyl hydroperoxides. The enzyme, which utilizes NADPH generated by the photosynthetic electron transfer system, protects the cells from lipid peroxidation. Group: Enzymes. Synonyms: slr1171 (gene name); slr1992 (gene name); hydroperoxy fatty acid:NADPH oxidoreductase. Enzyme Commission Number: EC 1.11.1.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0504; hydroperoxy fatty acid reductase; EC 1.11.1.22; slr1171 (gene name); slr1992 (gene name); hydroperoxy fatty acid:NADPH oxidoreductase. Cat No: EXWM-0504. | |
| linoleate 8R-lipoxygenase | The enzyme contains heme. The bifunctional enzyme from Aspergillus nidulans uses different heme domains to catalyse two separate reactions. Linoleic acid is oxidized within the N-terminal heme peroxidase domain to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate, which is subsequently isomerized by the C-terminal P-450 heme thiolate domain to (5S,8R,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate (cf. EC 5.4.4.5, 9,12-octadecadienoate 8-hydroperoxide 8R-isomerase). The bifunctional enzyme from Gaeumannomyces graminis also catalyses the oxidation of linoleic acid to (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate, but its second domain isomerizes it to (7S,8S,9Z,12Z)-5,8-dihydroxyoctadeca-9,12-dienoate (cf. EC 5.4.4.6, 9,12-octadecadienoate 8-hydroperoxide 8S-isomerase). Group: Enzymes. Synonyms: linoleic acid 8R-dioxygenase; 5,8-LDS (bifunctional enzyme); 7,8-LDS (bifunctional enzyme); 5,8-linoleate diol synthase (bifunctio. Enzyme Commission Number: EC 1.13.11.60. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0580; linoleate 8R-lipoxygenase; EC 1.13.11.60; linoleic acid 8R-dioxygenase; 5,8-LDS (bifunctional enzyme); 7,8-LDS (bifunctional enzyme); 5,8-linoleate diol synthase (bifunctional enzyme); 7,8-linoleate diol synthase (bifunctional enzyme); PpoA. Cat No: EXWM-0580. | |
| Liproxstatin-1 hydrochloride | Liproxstatin-1 is a potent inhibitor of ferroptosis, a form of regulated necrosis associated with the iron-dependent accumulation of lipid hydroperoxides. Synonyms: N-[(3-Chlorophenyl)methyl]spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine hydrochloride. Grades: ≥98% by HPLC. CAS No. 2250025-95-5. Molecular formula: C19H21ClN4·HCl. Mole weight: 377.31. | |
| Methyl 3,17-Dioxo-4-androsten-19-oate | A methoxy hydroperoxide androstenedione derivative; analog of a potential aromatase intermediate. Group: Biochemicals. Alternative Names: 3,17-Dioxo-androst-4-en-19-oic Acid Methyl Ester. Grades: Highly Purified. CAS No. 22256-03-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ML 351 | ML 351 is a potent and selective inhibitor of 12/15-lipoxygenase (IC50 value 200 nM against human 12/15-LOX), which catalyzes the oxidation of polyunsaturated fatty acids to produce unsaturated fatty acid hydroperoxides. Studies indicate that ML351 is protective against oxidative glutamate toxicity in mouse neuronal HT22 cells, and reduces infarct size following permanent focal ischemia in a mouse model of ischemic stroke. Synonyms: ML 351; ML-351; ML351; CID 664510; CID664510; CID-664510; 5-(methylamino)-2-naphthalen-1-yl-1,3-oxazole-4-carbonitrile. Grades: 98%. CAS No. 847163-28-4. Molecular formula: C15H11N3O. Mole weight: 249.27. | |
| Native Bovine Glutathione Peroxidase | Glutathione peroxidase is an enzyme which reduced lipid hydroperoxides into their corresponding alcohols. It also reduces free hydrogen peroxide in to water. In vivo it is responsible for protecting hemoglobin from oxidative breakdown. Applications: Glutathione peroxidase from bovine erythr ocytes was used as a positive control in cloning and characterization of full-length cdnas encoding two glutathione peroxidases (gpxs) from globodera rost ochiensis. it was used for the determination of glutathione peroxidase activity in human milk. Group: Enzymes. Synonyms: EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Enzyme Commission Number: EC 1.11.1.9. CAS No. 9013-66-5. Mole weight: mol wt 84.5 kDa. Activity: > 300 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing 25% sucrose and 2.5% dithiothreitol with sodium phosphate buffer salts. Source: Bovine erythr ocytes. Species: Bovine. EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Cat No: NATE-0322. | |
| Native Escherichia coli Thioredoxin Reductase | Thioredoxin reductase (TrxR) is an NADPH-dependent oxidoreductase containing one FAD per subunit that reduces the active site disulfide in oxidised thioredoxin (Trx). The molecular weight of the isozymes from mammalian sources vary between 55-67 kDa as compared with 35 kDa in prokaryotes, plants or yeast. The substrate specificity of the mammalian enzyme is much broader than the prokaryotic enzyme reducing both mammalian and E. coli thioredoxins as well as well as non-disulfide substrates such selenite, lipoic acids, lipid hydroperoxides and hydrogen peroxide. Applications: Thioredoxin reductase from escherichia coli can be used in peroxidase-coupled thioredoxin system assay for assessing the peroxidase activitiy of cys-based thiol peroxidases. the product was used for determining the enzymatic activity of his6-ahp1p. Group: Enzymes. Synonyms: NADP-thioredoxi. Enzyme Commission Number: EC 1.8.1.9. CAS No. 9074-14-0. TrxR. Activity: >25 units/mg protein (Bradford). Storage: 2-8°C. Form: ammonium sulfate suspension; Suspension in 3.6 M (NH4)2SO4 containing 30 mM potassium phosphate buffer, pH 7.5, and 2 mM EDTA. Source: Escherichia coli. NADP-thioredoxin reductase; NADPH-thioredoxin reductase; thioredoxin reductase (NADPH); NADPH2:oxidized thioredoxin oxidoreductase; thioredoxin-disulfide reductase; EC 1.8.1.9; TrxR. Cat No: NATE-0718. | |
| Native Human Glutathione Peroxidase | Glutathione peroxidase is an enzyme which reduced lipid hydroperoxides into their corresponding alcohols. It also reduces free hydrogen peroxide in to water. In vivo it is responsible for protecting hemoglobin from oxidative breakdown. At the reported ph optimum of 8.8, we have found the activity to be approx. 10 times that at ph 7.0. however, to remain consistent with literature and avoid complications arising from non-enzymatic oxidation of gsh, our unit is defined at ph 7.0. Group: Enzymes. Synonyms: EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Enzyme Commission Number: EC 1.11.1.9. CAS No. 9013-66-5. GSH-Px. Activity: > 30 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing 25% sucrose, 3% dithiothreitol, and sodium phosphate buffer salts. Source: Human erythr ocytes. Species: Human. EC 1.11.1.9; GSH peroxidase; selenium-glutathione peroxidase; reduced glutathione peroxidase; 9013-66-5; GSH-Px, Glutathione:hydrogen-peroxide oxido-reductase; Glutathione Peroxidase. Cat No: NATE-0323. | |
| Native Rat Thioredoxin Reductase | Thioredoxin reductase (TrxR) is an NADPH-dependent oxidoreductase containing one FAD per subunit that reduces the active site disulfide in oxidised thioredoxin (Trx). The molecular weight of the isozymes from mammalian sources vary between 55-67 kDa as compared with 35 kDa in prokaryotes, plants or yeast. The substrate specificity of the mammalian enzyme is much broader than the prokaryotic enzyme reducing both mammalian and E. coli thioredoxins as well as well as non-disulfide substrates such selenite, lipoic acids, lipid hydroperoxides and hydrogen peroxide. Applications: Thioredoxin reductase from rat liver can be used for studying the uptake and reduction of a-lipoic acid... NADP-thioredoxin reductase; NADPH-thioredoxin reductase; thioredoxin reductase (NADPH); NADPH2:oxidized thioredoxin oxidoreductase; thioredoxin-disulfide reductase; EC 1.8.1.9; TrxR; 9074-14-0. Enzyme Commission Number: EC 1.8.1.9. CAS No. 9074-14-0. TrxR. Activity: > 100 units/mg protein (Bradford). Storage: -20°C. Form: buffered aqueous glycerol solution; Solution in 50 mM Tris-HCl, pH 7.5, 300 mM NaCl, 1 mM EDTA, and 10% glycerol. Source: Rat liver. Species: Rat. NADP-thioredoxin reductase; NADPH-thioredoxin reductase; thioredoxin reductase (NADPH); NADPH2:oxidized thioredoxin oxidoreductase; thioredoxin-disulfide reductase; EC 1.8.1.9; TrxR; 9074-14-0. Cat No: NATE-0713. | |
| Oxidation-Reduction Compound Library | A unique collection of 1279 compounds with defined prooxidant or antioxidant activity can be used for HTS and HCS; - Contains hydroperoxides, polyphenolics, metal chelators, thiols, thiol traps, radical scavengers, lazaroids and glutathione modulators as well as small molecule enzyme mimetics for SOD and glutathione peroxidase, and antioxidant natural products, etc. ?- Structurally diversified with potent bioactivity and cell permeable; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2900. Categories: Oxidation-Reduction Compounds Libraries. |  |
| peroxiredoxin | Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant proteins. They can be divided into three classes: typical 2-Cys, atypical 2-Cys and 1-Cys peroxiredoxins. The peroxidase reaction comprises two steps centred around a redox-active cysteine called the peroxidatic cysteine. All three peroxiredoxin classes have the first step in common, in which the peroxidatic cysteine attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid) (see mechanism). The second step of the peroxidase reaction, the regeneration of cysteine from S-hydroxycysteine, distinguishes the three peroxiredoxin classes. For typical 2-Cys Prxs, in the second step, the peroxidatic S-hydr...se thioredoxin as an electron donor. The 1-Cys Prxs conserve only the peroxidatic cysteine, so that its oxidized form is directly reduced to cysteine by the reductant molecule. Group: Enzymes. Synonyms: thioredoxin peroxidase; tryparedoxin peroxidase; alkyl hydroperoxide reductase C22; AhpC; TrxPx; TXNPx; Prx; PRDX. Enzyme Commission Number: EC 1.11.1.15. CAS No. 207137-51-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0496; peroxiredoxin; EC 1.11.1.15; 207137-51-7; thioredoxin peroxidase; tryparedoxin peroxidase; alkyl hydroperoxide reductase C22; AhpC; TrxPx; TXNPx; Prx; PRDX. Cat No: EXWM-0496. | |
| plant seed peroxygenase | A heme protein with calcium binding motif (caleosin-type). Enzymes of this type include membrane-bound proteins found in seeds of different plants. They catalyse the direct transfer of one oxygen atom from an organic hydroperoxide, which is reduced into its corresponding alcohol to a substrate which will be oxidized. Reactions catalysed include hydroxylation, epoxidation and sulfoxidation. Preferred substrate and co-substrate are unsaturated fatty acids and fatty acid hydroperoxides, respectively. Plant seed peroxygenase is involved in the synthesis of cutin. Group: Enzymes. Synonyms: plant peroxygenase, soybean peroxygenase. Enzyme Commission Number: EC 1.11.2.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0514; plant seed peroxygenase; EC 1.11.2.3; plant peroxygenase, soybean peroxygenase. Cat No: EXWM-0514. | |
| prostamide/prostaglandin F2α synthase | The enzyme contains a thioredoxin-type disulfide as a catalytic group. Prostamide H2 and prostaglandin H2 are the best substrates; the latter is converted to prostaglandin F2&alpha. The enzyme also reduces tert-butyl hydroperoxide, cumene hydroperoxide and H2O2, but not prostaglandin D2 or prostaglandin E2. Group: Enzymes. Synonyms: prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Enzyme Commission Number: EC 1.11.1.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0502; prostamide/prostaglandin F2α synthase; EC 1.11.1.20; prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Cat No: EXWM-0502. | |
| Traumatic Acid | Traumatic Acid, is the product of a biosynthetic pathway from a physiological role of alpha-ketol fatty acids in plant lipid hydroperoxide lyase metabolism. This compound is also used in would healing as it stimulates cell division to form a protective callus around the wound site. Group: Biochemicals. Grades: Highly Purified. CAS No. 6402-36-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C12H20O4, Molecular Weight: 228.28. US Biological Life Sciences. | Worldwide |
| ZZW-115 | ZZW-115 is a potent NUPR1 inhibitor. ZZW-115 induces ferroptosis in a mitochondria-dependent manner. ZZW-115 induces ROS accumulation followed by a ferroptotic cell death, which could be prevented by ferrostatin-1 (Fer-1) and ROS-scavenging agents. In addition, ZZW-115-treatment increases the accumulation of hydroperoxided lipids in these cells. ZZW-115-induced mitochondrial morphological changes, compatible with the ferroptotic process, as well as mitochondrial network disorganization and strong mitochondrial metabolic dysfunction, which are rescued by both Fer-1 and N-acetylcysteine (NAC). Of note, the expression of TFAM, a key regulator of mitochondrial biogenesis, is downregulated by ZZW-115. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ZZW-115; ZZW 115; ZZW115. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 801991-87-7. Molecular formula: C24H31F3N4S. Mole weight: 464.6. Purity: >98%. IUPACName: N,N-dimethyl-2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethan-1-amine. Canonical SMILES: FC(C(C=C1N2CCCN3CCN(CCN(C)C)CC3)=CC=C1SC4=C2C=CC=C4)(F)F. Product ID: ACM801991877. Alfa Chemistry ISO 9001:2015 Certified. | |
| 1, 3-Bis (methoxymethoxy) -5-[ (1E) -2-[4- (methoxymethoxy) phenyl]ethenyl]-benzene | 1, 3-Bis (methoxymethoxy) -5-[ (1E) -2-[4- (methoxymethoxy) phenyl]ethenyl]-benzene is a useful synthetic intermediate in the synthesis of Resveratrol Impurity B (H950990); an impurity of Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1 and also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Grades: Highly Purified. CAS No. 1414361-09-3. Pack Sizes: 1g, 10g. Molecular Formula: C20H24O6, Molecular Weight: 360.4. US Biological Life Sciences. | Worldwide |
| 3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-5-(phenylmethoxy)-phenol | 3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-5-(phenylmethoxy)-phenol is the impurity C of Resveratrol (R150000); a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1 and also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Grades: Highly Purified. CAS No. 678149-02-5. Pack Sizes: 5mg, 50mg. Molecular Formula: C21H18O3, Molecular Weight: 318.37. US Biological Life Sciences. | Worldwide |
| 3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-5-(phenylmethoxy)-phenol-d7 | 3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-5-(phenylmethoxy)-phenol-d7 is the isotope labelled analog of 3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-5-(phenylmethoxy)-phenol (H950995); the impurity C of Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1 and also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C21H11D7O3, Molecular Weight: 325.41. US Biological Life Sciences. | Worldwide |
| Allyl Bromide (Stabilized with Propylene Oxide) | Allyl Bromide is used as a reagent in the synthesis of Resveratrol derivatives. Resveratrol (R150000) is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Alternative Names: 3-Bromo-1-propene; 1-Bromo-2-propene; 2-Propenyl Bromide; 3-Bromo-1-propene; 3-Bromopropene; 3-Bromopropylene; Allyl Bromide; NSC 7596. Grades: Highly Purified. CAS No. 106-95-6. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| Allyl-d5 Bromide | Isotope labelled Allyl Bromide is used as a reagent in the synthesis of Resveratrol derivatives. Resveratrol (R150000) is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Alternative Names: 3-Bromo-1-propene-d5; 1-Bromo-2-propene-d5; 2-Propenyl Bromide-d5; 3-Bromo-1-propene-d5; 3-Bromopropene-d5; 3-Bromopropylene-d5; Allyl Bromide-d5; NSC 7596-d5. Grades: Highly Purified. CAS No. 102910-37-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| cis-Resveratrol | Minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Alternative Names: 5-[(1Z)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol; cis-3,4',5-Trihydroxystilbene; Z-5-[2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol; (Z)-Resveratrol. Grades: Highly Purified. CAS No. 61434-67-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| GXpep-3 | GXpep-3 is a novel polypeptide inhibitor of phospholipid hydroperoxidase glutathione peroxidase (GPX4). Currently GPX4 is found to be a target which selectively induces iron-dependent cell death (ferroptosis) in cancer cells that express mutant Ras. GXpep-3 is promisingly developed to be a antitumor drug. Uses: Antitumor. Synonyms: GXpep 3; GXpep3. | |
| Nafazatrom | Nafazatrom is a pyrazolinone derivative. It increases endogenous prostacyclin (PGI2) and has potential antimetastatic activities. It is used an antithrombotic drug that increases PGI2 levels. It inhibits the key prostaglandin catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase, which prolongs the biological half-life of PGI2 and prevents intravascular coagulation. It also serves as a reducing cofactor with the hydroperoxidase moiety of cyclooxygenase and accelerates the conversion of arachidonic acid into precursors of PGI2. It is a lipoxygenase inhibitor, reduces stimulated Prolactin secretion. It also reduces the incidence of accompanying arrhythmias in myocardial injuries. Uses: Nafazatrom is used an antithrombotic drug. Synonyms: 2,4-Dihydro-5-methyl-2-[2-(2-naphthalenyloxy)ethyl]-3H-pyrazol-3-one; Bay-g-6575; BAY g 6575; 3-methyl-1-(2-(naphthalen-2-yloxy)ethyl)-1H-pyrazol-5(4H)-one. Grades: 98%. CAS No. 59040-30-1. Molecular formula: C16H16N2O2. Mole weight: 268.32. | |
| Native Glycine max (soybean) Lipoxidase | Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure. Applications: The soybean enzyme will use arachidonic acid as a substrate, with ~ 15% of the activity indicated using linoleic acid as the substrate; the product of arachidonic acid oxidation is 12-or 15-hydroperoxyarachidonic acid (12-hpete or 15-hpete). Group: Enzymes. Synonyms: Lipoxygenases; EC 1.13.11.12; 9029-60-1; 13-lipoxidase; carotene oxidase; 13-lipoperoxidase; fat oxidase; 13-lipoxydase; lionoleate:O2 13-oxidoreductase; linoleate 13S-lipoxygenase. Enzyme Commission Number: EC 1.13.11.12. CAS No. 9029-60-1. Lipoxygenase. Mole weight: mol wt 108 kDa (two 54 kDa subunits). Activity: Type I, 500,000-1,000,000 units/mg protein; Type II, > 50,000 units/mg solid. Storage: 2-8°C. Form: Type I, ammonium sulfate suspension, Suspension in 2.3 M (NH4)2SO4 solution, pH approx. 6.0; Type II, lyophilized powder, Contains stabilizer and NaCl. Source: Glycine max (soybean). Lipoxygenases; EC 1.13.11.12; 9029-60-1; 13-lipoxidase; carotene oxidase; 13-lipoperoxidase; fat oxidase; 13-lipoxydase; lionoleate:O2 13-oxidoreductase; linoleate 13S-lipoxygenase. Cat No: NATE-0407. | |
| Resveratrol | Resveratrol (also known as SRT-501) is a phytoalexin derived from grapes and other food products with antioxidant and potential chemopreventive activities. Resveratrol induces phase II drug-metabolizing enzymes (anti-initiation activity), mediates anti-inflammatory effects and inhibits cyclooxygenase and hydroperoxidase functions (anti-promotion activity), and induces promyelocytic leukemia cell differentiation (anti-progression activity), thereby exhibiting activities in three major steps of carcinogenesis. This agent may inhibit TNF-induced activation of NF-kappaB in a dose-and time-dependent manner. Resveratrol is a natural compound used in cosmetic material. Uses: Ingredient of health care products. Synonyms: trans-Resveratrol; SRT-501; SRT 501; SRT501; RM1812; RM 1812; RM-1812; CA1201; CA 1201; CA-1201; Resvida; Vineatrol 20M; 3,4',5-Trihydroxystilbene; 3,4',5-Stilbenetriol. Grades: ≥98%. CAS No. 501-36-0. Molecular formula: C14H12O3. Mole weight: 228.24. | |
| Resveratrol-13C6 | Minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
