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4-Hydroxyisoleucine is an orally active amino acid that can be isolated from fenugreek seeds. 4-Hydroxyisoleucine displays insulinotropic and antidiabetic properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Hydroxy-L-isoleucine. CAS No. 781658-23-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N6858.
4-Hydroxyisoleucine
4-Hydroxyisoleucine, which comes from the seeds of Trigonella foenum-graecum L, could inhibit palmitate-induced, ROS-associated inflammation and restored insulin sensitivity through regulating IRS-1 function. It acts to improve insulin resistance by promoting mitochondrial biogenesis in high fructose diet fed STZ induced diabetic rats. Besides, 4-Hydroxyisoleucine could remarkably improve high glucose-induced IR in 3T3-L1 adipocytes. Meanwhile, 4-HIL could inhibit the secretion of TNF-alpha. Synonyms: 4-HYDROXY-L-ISOLEUCINE; (2S,3R)-2-aMino-4-hydroxy-3-Methylpentanoic acid. Grades: >98%. CAS No. 781658-23-9. Molecular formula: C6H13NO3. Mole weight: 147.17.
4-Hydroxyisoleucine (Hydroxyisoleucine)
4-Hydroxyisoleucine (Hydroxyisoleucine). Group: Biochemicals. Alternative Names: 4-Hydroxy-L-isoleucine; (2S,3R,4S)-4-Hydroxy-L-isoleucine,55399-93-4. Grades: Plant Grade. CAS No. 781658-23-9. Pack Sizes: 20mg. Molecular Formula: C6H13NO3, Molecular Weight: 147.172. US Biological Life Sciences.
2-?Ethyl-?2,?5-?dihydro-?4-?hydroxy-?3-?methyl-?5-?oxo-2-?furancarboxylic Acid Methyl Ester is an by-product intermediate formed during the synthesis of 4,5-Dimethyl-3-hydroxy-2(5H)-furanone (D473600), a fragrant compound that is a key indicator of maple syrup urine disease, a disorder affecting newborn children that is the result of its inability to properly metabolize Valine (V094205), Leucine (L330110) and Isoleucine (I820175). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is naturally found in fenugreek seeds, and is an odourant present in sherry wines. Group: Biochemicals. Grades: Highly Purified. CAS No. 112026-00-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H12O5. US Biological Life Sciences.
Worldwide
3-Hydroxy-2-methylbutyryl-CoA
3-Hydroxy-2-methylbutyryl-CoA is an intermediate in the metabolization of Isoleucine to 2-Methylbutyryl-CoA. Synonyms: S-(3-Hydroxy-2-methylbutyrate) Coenzyme A; S-(3-Hydroxy-2-methylbutanoate) Coenzyme A; 2-Methyl-3-hydroxybutyryl-CoA. CAS No. 6701-38-8. Molecular formula: C26H44N7O18P3S. Mole weight: 867.65.
acetolactate synthase
This enzyme requires thiamine diphosphate. The reaction shown is in the pathway of biosynthesis of valine; the enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine. Group: Enzymes. Synonyms: α-acetohydroxy acid synthetase; α-acetohydroxyacid synthase; α-acetolactate synthase; α-acetolactate synthetase; acetohydroxy acid synthetase; acetohydroxyacid synthase; acetolactate pyruvate-lyase (carboxylating); acetolactic synthetase. Enzyme Commission Number: EC 2.2.1.6. CAS No. 9027-45-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2033; acetolactate synthase; EC 2.2.1.6; 9027-45-6; α-acetohydroxy acid synthetase; α-acetohydroxyacid synthase; α-acetolactate synthase; α-acetolactate synthetase; acetohydroxy acid synthetase; acetohydroxyacid synthase; acetolactate pyruvate-lyase (carboxylating); acetolactic synthetase. Cat No: EXWM-2033.
Enniatin A (Lateritin I)
Enniatins are a family of depsipeptides produced several Fusarium species. The enniatins have been shown to act as ionophores. More recently their effects on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin A is one of four major analogs of the enniatin complex and has previously not been available for investigation. Cyclohexadepsipeptide mycotoxin. One of four major analogs in the enniatin complex. Commonly found food contaminant in cereals and their products. Ionophore antibiotic. Incorporation into the cell membrane forms dimeric structures that transport monovalent ions across the membrane (especia...:Fusarium sp. MST-FP1765. Group: Biochemicals. Alternative Names: Lateritin I; Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-isoleucyl]; N-(D-2-Hydroxy-3-methylbutyryl)-N-methyl-Isoleucine Trimol. Cyclic Ester; 1,7,13-Trioxa-4,10,16-triazacyclooctadecane Cyclic Peptide Deriv.;Cyclo(D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl-D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl-D-α-hydroxyisovaleryl-N-methyl-L-isoleucyl). Grades: Highly Purified. CAS No. 2503-13-1. Pack Sizes: 500ug. Molecular Formula: C??H??N?O?, Molecular Weight: 681.9. US Biological Life Sciences.
Worldwide
Hypeptin
Hypeptin is produced by the strain of Pseudomonas sp. PB-6269. Hypeptin has the activity of anti-anaerobic gram-positive bacteria and anti-anaerobic gram-negative bacteria (weakly), and also has the effect on aerobic gram-positive bacteria. Synonyms: UNII-0V1I6WBK4F; L-Isoleucine, N-(N-(N-(N2-(N2-(N2-(N-L-alanyl-D-leucyl)-D-arginyl)-erythro-3-hydroxy-L-asparaginyl)-erythro-3-hydroxy-D-asparaginyl)-erythro-beta-hydroxy-L-tyrosyl)-threo-3-hydroxy-L-leucyl)-, lambda-lactone. Grades: >98%. CAS No. 124883-38-1. Molecular formula: C44H71N13O15. Mole weight: 1022.11.
Methyl 2-((1R,3R)-3-amino-1-hydroxy-4-methylpentyl)thiazole-4-carboxylate hydrochloride, a chemical substance employed as a research tool in the biomedical sector, serves to shed light upon the intricate metabolic pathways implicated in L-isoleucine metabolism. Through this elucidation, the compound becomes instrumental in deepening our understanding of perplexing genetic conditions, including the notorious maple syrup urine disease, whilst simultaneously offering fascinating insights into potential cures for both cancer and neurological maladies. Driven by its incredible versatility and promising indications, researchers endeavor to unearth the full extent of Methyl 2-((1R,3R)-3-amino-1-hydroxy-4-methylpentyl)thiazole-4-carboxylate hydrochloride's vast potential in the future. Synonyms: 4-Thiazolecarboxylic acid, 2-[(1R,3R)-3-amino-1-hydroxy-4-methylpentyl]-, methyl ester, hydrochloride (1:1). CAS No. 921927-91-5. Molecular formula: C11H19ClN2O3S. Mole weight: 294.8.
ROSEOTOXIN
Roseotoxin is a cyclic depeptide that can improve allergic contact dermatitis through a unique anti-inflammatory mechanism. Synonyms: CYCLO[2-HYDROXY-4-METHYL-PENTANOIC ACID-3-METHYL-PROLIN-ISOLEUCINE-N-METHYL-VALINE-N-METHYL-ALANINE-BETA-ALANINE]; ROSEOTOXIN; roseotoxin B; Cyclo[2-Hydroxy-4-methyl-pentanoic acid-3-methyl-prolin-Isoleucine-N-methyl-Valine-N-methyl-Alanine-beta-Alanine]; Cy. CAS No. 55466-29-0. Molecular formula: C30H49N5O7. Mole weight: 591.74.
Phomopsinamine is a potent mycotoxin and an effective microtubule inhibitor produced by the fungus, Phomopsis leptostromiformis. Phomopsinamine is formed by hydrolysis of the dicarboxylic acid of phomopsin A. Synonyms: Isoleucinamide, (βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-, cyclic (15?3)-ether, (2E)-; Phomopsinamine A; (2E)-(βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-isoleucinamide, cyclic (15?3)-ether; (S)-N-((E)-1-amino-3-methyl-1-oxopent-2-en-2-yl)-1-((3R,4S,7S,10S,11S)-15-chloro-3-ethyl-16,11-dihydroxy-3-methyl-10-(methylamino)-6,9-dioxo-7-(prop-1-en-2-yl)-2-oxa-5,8-diaza-1(1,3)-benzenacycloundecaphane-4-carbonyl)-2,5-dihydro-1H-pyrrole-2-carboxamide. Grades: >95% by HPLC. CAS No. 89085-54-1. Molecular formula: C32H43ClN6O8. Mole weight: 675.17.
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