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4-Hydroxy-4-Phenylpiperidine Hydrochloride acts as an anticonvulsant due to the substituted piperidine in the structure. It also, being a metabolite of Haloperidol (H103700), may contain antipsychotic properties. Group: Biochemicals. Alternative Names: 4-Phenyl-4-hydroxypiperidine; 4-Phenyl-4-piperidinol Hydrochloride; NSC 71658 Hydrochloride; 1,4'-Bipiperidin]-4'-ol Hydrochloride. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences.
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JDTic
A 4-phenylpiperidine derivative, for the κ-opioid receptor. Uses: A selective opioid kappa receptor antagonist. Synonyms: (3R)-7-hydroxy-N-[1-[(3R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide. Grades: ≥98%. CAS No. 361444-66-8. Molecular formula: C28H39N3O3. Mole weight: 465.64.
JDTic dihydrochloride
JDTic dihydrochloride is a highly selective antagonist for the κ-opioid receptor with IC50 value of 0.02nM without affecting the μ- or δ-opioid receptors. It is a 4-phenylpiperidine derivative and distantly structurally related to analgesic drugs such as meperidine and ketobemidone and more closely to the mu opioid antagonist alvimopan. It is structurally distinct from other kappa antagonists such as norbinaltorphimine. It is more selective and potent for KOR activity than other KOR antagonists. It is shown to block the antinociceptive response of nicotine in the tail-flick test with a dose-dependent manner. It can also block the nicotine withdrawal signs in mice vi... it can also block the nicotine withdrawal signs in mice via effecting the expression of a cpa associated with nicotine withdrawal. it is also reported to decrease the number of somatic withdrawal signs in morphine-dependent rats. it may produce antidepressant and anxiolytic effects and may be used in the treatment of addiction to cocaine and morphine. Synonyms: JDTic (2HCl);(3R)-1,2,3,4-Tetrahydro-7-hydroxy-N-[(1S)-1-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-2-methylpropyl]-3-isoquinolinecarboxamide hydrochloride;(R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4- . Grades: 95%. CAS No. 785835-79-2. Molecular formula: C28H41Cl2N3O3. Mole weight: 538.55.
CP 101606
CP 101606 is a potent and selective NR2B antagonist of N-Methyl-D-Aspartate (NMDA) glutamate receptors. It decreases pentylenetetrazol-induced seizures. Synonyms: CP-101606; CP 101606; CP101606; Traxoprodil; 1-((1S,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol. Grades: 99%. CAS No. 134234-12-1. Molecular formula: C20H25NO3. Mole weight: 327.42.
A highly selective antagonist for NR2B subunit containing nMDA receptors (IC50 = 0.039uM for NR2B and >100uM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research. Group: Biochemicals. Grades: Highly Purified. CAS No. 134234-12-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Dechloro Haloperidol
Dechloro Haloperidol is also known as Haloperidol impurity B. Synonyms: 1-(4-Fluorophenyl)-4-(4-Hydroxy-4-Phenyl-1-Piperidyl)Butan-1-One; 1-(4-Fluorophenyl)-4-(4-hydroxy-4-phenyl-1-piperidinyl)-1-butanone; 4'-Fluoro-4-(4-hydroxy-4-phenylpiperidino)butyrophenone; Haloperidol impurity B; R 1838. Grades: > 95%. CAS No. 3109-12-4. Molecular formula: C21H24FNO2. Mole weight: 341.42.
Haloperidol EP Impurity A
Haloperidol EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(4-fluorophenyl)-4-(4-hydroxy-4-phenylpiperidin-1-yl)butan-1-one. CAS No. 3109-12-4. Molecular Formula: C21H24FNO2. Mole Weight: 341.42. Catalog: APB3109124.
Loperamide Impurity 4
Loperamide Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide. Molecular Formula: C29H34N2O2. Mole Weight: 442.26. Catalog: APB02146.