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Hydroxylation Single Nanotubes 0.7-2.5 nm. Uses: Designed for use in research and industrial production. Product Category: Carbon Nanotubes. CAS No. 7440-44-0. Product ID: ACM7440440-241. Alfa Chemistry ISO 9001:2015 Certified.
Industrial grade hydroxylation MWCNTs 10-30nm
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, O
Industrial grade hydroxylation MWCNTs 20-40nm
Carbon black oil appears as a dark colored liquid with a petroleum-like odor. Less dense than water and insoluble in water. Vapors heavier than air.;Carbon, activated is a black grains that have been treated to improve absorptive ability. May heat spontaneously if not properly cooled after manufacture.;Carbon, animal or vegetable origin appears as a black powder or granular mixed with a tar or starch and water binder pressed into regular lumps or briquettes. Heats slowly and ignites in air especially if wet.;Graphite (natural) appears as a mineral form of the element carbon. Hexagonal crystals or thin leaf-like layers. Steel-gray to black with a metallic luster and a greasy feel. An electrical conductor. Used for high-temperature crucibles, as a lubricant and in "lead" pencils.;DryPowder; DryPowder, Liquid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, WetSolid, OtherSolid, Liquid; DryPowder, WetSolid, Liquid; Liquid; OtherSolid; OtherSolid, GasVapor, Liquid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid, Liquid; WetSolid; WetSolid, Liquid;OtherSolid; PelletsLargeCrystals;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, OtherSolid; WetSolid;DryPowder; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, WetSolid; Liquid; OtherSolid; PelletsLargeCrystals; PelletsLargeCrystals, O
1,4-DPCA
The pro-angiogenic factor HIF-1α is targeted for destruction in non-hypoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH). It is a promotor of wound healing and tissue regeneration in mice. Synonyms: 1,4-dihydrophenonthrolin-4-one-3-carboxylic acid. Grades: ≥98%. CAS No. 331830-20-7. Molecular formula: C13H8N2O3. Mole weight: 240.2.
1- (4-Fluorophenyl) piperazine
1- (4-Fluorophenyl) piperazine is a major metabolite of Niaparazine, a sedative, hypnotic drug. Metabolites of Niaprazine occurred by N-dealkylation, N-dearylation, aromatic hydroxylation and N-oxidation. Group: Biochemicals. Alternative Names: 1- (p-Fluorophenyl) piperazine; N- (4-Fluorophenyl) piperazine; N- (p-Fluorophenyl) piperazine; p-Fluorophenyl piperazine. Grades: Highly Purified. CAS No. 2252-63-3. Pack Sizes: 1g. US Biological Life Sciences.
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1- (4-Fluorophenyl) piperazine Dihydrochloride
1- (4-Fluorophenyl) piperazine is a major metabolite of Niaparazine, a sedative, hypnotic drug. Metabolites of Niaprazine occurred by N-dealkylation, N-dearylation, aromatic hydroxylation and N-oxidation. Group: Biochemicals. Alternative Names: 1- (4-Fluorophenyl) piperazine Hydrochloride. Grades: Highly Purified. CAS No. 64090-10-3. Pack Sizes: 1g. US Biological Life Sciences.
1-(5-Chloro-2-hydroxyphenyl)-2,2,2-trifluoroethanone is used as a reagent in the synthesis of 1,2,3-benzoxathiazine-based oxaziridine derivatives as potent oxygen-atom transfer agents for catalytic carbon-hydrogen hydroxylation and alkene epoxidation. Group: Biochemicals. Grades: Highly Purified. CAS No. 870614-04-3. Pack Sizes: 10mg, 50mg. Molecular Formula: C8H4ClF3O2, Molecular Weight: 224.56. US Biological Life Sciences.
1-(5-Chloro-2-methoxyphenyl)-2,2,2-trifluoroethanone is used as a reagent in the synthesis of 1,2,3-benzoxathiazine-based oxaziridine derivatives as potent oxygen-atom transfer agents for catalytic carbon-hydrogen hydroxylation and alkene epoxidation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H6ClF3O2. US Biological Life Sciences.
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16 β-Hydroxytestosterone
16 β-Hydroxytestosterone is a testosterone metabolite synthesized using an active site substitution in cytochrome P450 resulting in steroid hydroxylation. Group: Biochemicals. Grades: Highly Purified. CAS No. 17528-90-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C19H28O3, Molecular Weight: 304.42. US Biological Life Sciences.
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17α-hydroxyprogesterone deacetylase
A microsomal cytochrome P-450 (heme-thiolate) protein that catalyses two independent reactions at the same active site - the 17-hydroxylation of pregnenolone and progesterone, which is part of glucocorticoid hormones biosynthesis (EC 1.14.14.19), and the conversion of the 17-hydroxylated products via a 17,20-lyase reaction to form androstenedione and 3β-hydroxyandrost-5-en-17-one, leading to sex hormone biosynthesis. The activity of this reaction is dependent on the allosteric interaction of the enzyme with cytochrome b5 without any transfer of electrons from the cytochrome. The enzymes from different organisms differ in their substrate specificity. While the enzyme...son do not accept the former, and the enzyme from guinea pig does not accept the latter. Group: Enzymes. Synonyms: C-17/C-20 lyase; 17α-hydroxyprogesterone acetaldehyde-lyase; CYP17; CYP17A1 (gene name); 17α-hydroxyprogesterone 17,20-lyase. Enzyme Commission Number: EC 1.14.14.32. CAS No. 62213-24-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0930; 17α-hydroxyprogesterone deacetylase; EC 1.14.14.32; 62213-24-5; C-17/C-20 lyase; 17α-hydroxyprogesterone acetaldehyde-lyase; CYP17; CYP17A1 (gene name); 17α-hydroxyprogesterone 17,20-lyase. Cat No: EXWM-0930.
(1R)-(-)-10-Camphorsulfonamide
A useful synthetic intermediate. Used for asymmetric hydroxylation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences.
Worldwide
(1R)-(-)-10-Camphorsulfonyl Chloride
A useful synthetic intermediate. Used for asymmetric hydroxylation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences.
Worldwide
(1R)-(+)-(10-Camphorsulfonyl)imine
A useful synthetic intermediate. Used for asymmetric hydroxylation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences.
Worldwide
(1S)-(+)-10-Camphorsulfonamide
A useful synthetic intermediate. Used for asymmetric hydroxylation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences.
Worldwide
(1S)-(+)-10-Camphorsulfonyl Chloride
A useful synthetic intermediate. Used for asymmetric hydroxylation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences.
Worldwide
(1S)-(-)-(10-Camphorsulfonyl)imine
A useful synthetic intermediate. Used for asymmetric hydroxylation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences.
Worldwide
2,3-dihydroxybenzoate 3,4-dioxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing). Other names in common use include o-pyrocatechuate oxygenase, 2,3-dihydroxybenzoate 1,2-dioxygenase, 2,3-dihydroxybenzoic oxygenase, and 2,3-dihydroxybenzoate oxygenase. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: o-pyrocatechuate oxygenase; 2,3-dihydroxybenzoate 1,2-dioxygenase; 2,3-dihydroxybenzoic oxygenase; 2,3-dihydroxybenzoate oxygenase; 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing). Enzyme Commission Number: EC 1.13.11.14. CAS No. 9032-31-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0533; 2,3-dihydroxybenzoate 3,4-dioxygenase; EC 1.13.11.14; 9032-31-9; o-pyrocatechuate oxygenase; 2,3-dihydroxybenzoate 1,2-dioxygenase; 2,3-dihydroxybenzoic oxygenase; 2,3-dihydroxybenzoate oxygenase; 2,3-dihydroxybenzoate:oxygen 3,4-oxidoreductase (decyclizing). Cat No: EXWM-0533.
2-(4-Heptyn-1-yloxy)tetrahydro-2H-pyran
2-(4-Heptyn-1-yloxy)tetrahydro-2H-pyran is used as a reagent to synthesize tetradeuterio fatty acids, compounds that assist in the studies of enzyme-catalyzed hydroxylation reactions. Group: Biochemicals. Grades: Highly Purified. CAS No. 1420074-18-5. Pack Sizes: 250mg, 25g. Molecular Formula: C12H20O2, Molecular Weight: 196.29. US Biological Life Sciences.
Worldwide
(24S)-24,25-Dihydroxyvitamin D3
(24S)-24,25-Dihydroxycholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. Synonyms: (24S)-24,25-Dihydroxyvitamin D3; 55700-58-8; (24S)-Secalciferol; 24S,25-Dihydroxycholecalciferol; (24S)-24,25-dihydroxyvitamin D3 / (24S)-24,25-dihydroxycholecalciferol; (5Z,7E)-(3S,24S)-9,10-seco-5,7,10(19)-cholestatriene-3,24,25-triol; EVQ6RX7DAN; Secalciferol, (24S)-; 24S,25-Dihydroxyvitamin D3; (3S, 6R) -6- [ (1R, 3aS, 4E, 7aR) -4- [ (2Z) -2- [ (5S) -5-hydroxy-2-methylidenecyclohexylidene] ethylidene] -7a-methyl-2, 3, 3a, 5, 6, 7-hexahydro-1H-inden-1-yl] -2-methylheptane-2, 3-diol; 24(S),25-Dihydroxyvitamin D3; PRI-1202; LMST03020274; MFCD11114064; AKOS030526847; CS-0931; HY-15439; MS-27263; (24S)-24,25-Dihydroxyvitamin D3, >=95.0% (HPLC); 2,3-HEPTANEDIOL, 2-METHYL-6-((1R,3AS,4E,7AR)-OCTAHYDRO-4-((2Z)-2-((5S)-5-HYDROXY-2-METHYLENECYCLOHEXYLIDENE)ETHYLIDENE)-7A-METHYL-1H-INDEN-1-YL)-, (3S,6R)-. Grades: >98%. CAS No. 55700-58-8. Molecular formula: C27H44O3. Mole weight: 416.64.
25-Hydroxy Vitamin D3 3,3-Aminopropyl Ether
Vitamin D3 analog. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.[2] At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3] Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.[4][5]. Group: Biochemicals. Alternative Names: ( ε R, 1R, 3aS, 4E, 7aR) -4- [ (2Z) -2- [ (5S) -5- (3-Aminopropoxy) -2- methyl enecyclohexylidene] ethylidene] octahydro- α , α , ε , 7a-tetra methyl -1H-indene-1-pentanol; (3 β,5Z,7E)-3-(3-Aminopropoxy)-9,10-secocholesta-5,7,10(19)-trien-25-ol; 3-O-(2-Aminoethyl)-25-hydroxyvitamin D3. Grades: Highly Purified. CAS No. 163018-26-6. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
25-Hydroxyvitamin D3 3-Glucuronide
25-Hydroxyvitamin D3 3-Glucuronide is an glucuronidated conjugate of 5-Hydroxyvitamin D3, the principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-25-Hydroxy-9,10-secocholesta-5,7,10(19)-trien-3-yl β-D-Glucopyranosiduronic Acid. Grades: Purified. CAS No. 170512-14-8. Pack Sizes: 500ug. Molecular Formula: C??H??O?, Molecular Weight: 576.76. US Biological Life Sciences.
Worldwide
25-Hydroxyvitamin D3 3-Hemisuccinate
25-Hydroxyvitamin D3 3-Hemisuccinate is a conjugate of 5-Hydroxyvitamin D3 (C125700), the principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator. Also used in the preparation and synthesis of antisera to be used in the immunoassay of 25-Hydroxyvitamin D3. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-3-(Hydrogen Butanedioate)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; 25-Hydroxycholecalciferol-3-hemisuccinate; Calcidiol 3-Hemisuccinate. Grades: Highly Purified. CAS No. 69511-19-9. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
25-Hydroxyvitamin D3 3-Hemisuccinate-d6
25-Hydroxyvitamin D3 3-Hemisuccinate-d6 is the isotope labelled analog of 25-Hydroxyvitamin D3 3-Hemisuccinate (H995855); a conjugate of 5-Hydroxyvitamin D3 (C125700) which is the principal circulating form of vitamin D3 formed in the liver by hydroxylation at C-25. Calcium regulator. Also used in the preparation and synthesis of antisera to be used in the immunoassay of 25-Hydroxyvitamin D3. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C31H42D6O5, Molecular Weight: 506.75. US Biological Life Sciences.
Worldwide
25-Hydroxy Vitamin D3 3-Sulfate Sodium Salt
25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days. Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol 3-(Hydrogen Sulfate) Sodium Salt; 25-Hydroxyvitamin D3 3-Sulfate Sodium Salt; 25-Hydroxyvitamin D3 3 β-Sulfate Sodium Salt; Calcifediol 3-Sulfate Sodium Salt. Grades: Purified. Pack Sizes: 2.5mg. Molecular Formula: C??H??NaO?S, Molecular Weight: 502.68. US Biological Life Sciences.
Worldwide
25-Hydroxyvitamin D3 (Calcifediol)
A metabolite of Vitamin D. The principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; 25-hydroxycholecalcifero l; 25-Hydroxyvitamin D; 25-Hydroxyvitamin D3; Calcidiol; Didrogyl; Hidroferol; Ro 8-8892. Grades: Highly Purified. CAS No. 19356-17-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C??H??O?, Molecular Weight: 400.64. US Biological Life Sciences.
Worldwide
(25R)-5 β-Cholestane-3α,7α,26-triol
(25S)-5 β-Cholestane-3α,7α,26-triol, can be used in the study of stereospecific side-chain hydroxylations in the biosynthesis of chenodeoxycholic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 66807-58-7. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C27H48O3, Molecular Weight: 420.67. US Biological Life Sciences.
Worldwide
25(S)-27-Hydroxy cholesterol
25(S)-27-Hydroxy cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRα and LXRβ in vitro with EC50 values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis. Synonyms: (25S)-26-hydroxy cholesterol; 26-OHC. Grades: ≥95%. CAS No. 56845-83-1. Molecular formula: C27H46O2. Mole weight: 402.7.
(25S)-5 β-Cholestane-3α,7α,26-triol
(25S)-5 β-Cholestane-3α,7α,26-triol, can be used in the study of stereospecific side-chain hydroxylations in the biosynthesis of chenodeoxycholic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 66807-59-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C27H48O3, Molecular Weight: 420.67. US Biological Life Sciences.
Worldwide
2-aminobenzenesulfonate 2,3-dioxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of two atoms o oxygen into the other donor. The systematic name of this enzyme class is 2-aminobenzenesulfonate,NADH:oxygen oxidoreductase (2,3-hydroxylating, ammonia-forming). This enzyme is also called 2-aminosulfobenzene 2,3-dioxygenase. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: 2-aminosulfobenzene 2,3-dioxygenase. Enzyme Commission Number: EC 1.14.12.14. CAS No. 156621-16-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0683; 2-aminobenzenesulfonate 2,3-dioxygenase; EC 1.14.12.14; 156621-16-8; 2-aminosulfobenzene 2,3-dioxygenase. Cat No: EXWM-0683.
2-Bromo-LSD
2-Bromo-LSD (BOL-148; Bromolysergide) is a Dopamine Receptor antagonist that directly affects dopamine neurons in the substantia nigra neostriatum. 2-Bromo-LSD increases the hydroxylation of tyrosine in striatum and antagonizes the decrease of Apomorphine-induced DOPA accumulation. 2-Bromo-LSD also blocks the 5-HT Receptor mediated DOPA formation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BOL-148; Bromolysergide. CAS No. 478-84-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121675.
2-Cyano-5-fluorophenol
2-Cyano-5-fluorophenol is used in the study of substituent effect on fluorobenzene derivatives on cytochrome P 450-catalyzed hydroxylation at adjacent ortho aromatic carbon center. Group: Biochemicals. Grades: Highly Purified. CAS No. 186590-01-2. Pack Sizes: 1g, 2.5g. Molecular Formula: C7H4FNO, Molecular Weight: 137.11. US Biological Life Sciences.
Worldwide
2'-deoxymugineic-acid 2'-dioxygenase
Requires iron(II). It is also likely that this enzyme can catalyse the hydroxylation of 3-epihydroxy-2'-deoxymugineic acid to form 3-epihydroxymugineic acid. Group: Enzymes. Synonyms: IDS3. Enzyme Commission Number: EC 1.14.11.24. CAS No. 133758-62-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0641; 2'-deoxymugineic-acid 2'-dioxygenase; EC 1.14.11.24; 133758-62-0; IDS3. Cat No: EXWM-0641.
2-Methyl-1,2-di-4-pyridinyl-1-propanone
2-Methyl-1,2-di-4-pyridinyl-1-propanone is an analog of Metyrapone (M338990). Studies show that 2-Methyl-1,2-di-4-pyridinyl-1-propanone induced blockage of 18-hydroxylation in the adrenal cortex of rats which increased the activity in the zona glomerulosa and of the mineralocorticoids. Group: Biochemicals. Grades: Highly Purified. CAS No. 17286-92-9. Pack Sizes: 100mg, 500mg. Molecular Formula: C14H14N2O, Molecular Weight: 226.27. US Biological Life Sciences.
IQ-type carcinogens found in cooked food are biotransformed and bind to DNA through sequential N2-hydroxylation and. Group: Biochemicals. Alternative Names: NO2-MeIQx. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Requires ATP. The reaction in mammals possibly involves dehydrogenation to give a 24(25)-double bond followed by hydration. However, in amphibians such as the Oriental fire-bellied toad (Bombina orientalis), it is probable that the product is formed via direct hydroxylation of the saturated side chain of (25R)-3α,7α,12α-trihydroxy-5β-cholestan-26-oate and not via hydration of a 24(25) double bond. In microsomes, the free acid is preferred to the coenzyme A ester, whereas in mitochondria, the coenzyme A ester is preferred to the free-acid form of the substrate. Group: Enzymes. Synonyms: trihydroxycoprostanoyl-CoA oxidase; THC-CoA oxidase; THCA-CoA oxidase; 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA oxidase; 3α,. Enzyme Commission Number: EC 1.17.99.3. CAS No. 119799-47-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1103; 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA 24-hydroxylase; EC 1.17.99.3; 119799-47-2; trihydroxycoprostanoyl-CoA oxidase; THC-CoA oxidase; THCA-CoA oxidase; 3α,7α,12α-trihydroxy-5β-cholestanoyl-CoA oxidase; 3α,7α,12α-trihydroxy-5β-cholestan-26-oate 24-hydroxylase. Cat No: EXWM-1103.
3-carboxy-cis,cis-muconate cycloisomerase
This enzyme belongs to the family of isomerases, specifically intramolecular lyases. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: β-carboxymuconate lactonizing enzyme; 3-carboxymuconolactone hydrolase; 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.2. CAS No. 9075-77-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5621; 3-carboxy-cis,cis-muconate cycloisomerase; EC 5.5.1.2; 9075-77-8; β-carboxymuconate lactonizing enzyme; 3-carboxymuconolactone hydrolase; 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). Cat No: EXWM-5621.
3-epi-25-Hydroxy Vitamin D3
The epimer metabolite of Calcifediol or 25-hydroxyvitamin D3. Calcifediol (INN), also known as calcidiol, 25-hydroxycholecalcifero l, or 25-hydroxyvitamin D (abbreviated 25(OH)D),[1] is a prehormone that is produced in the liver by hydroxylation of vitamin D3(cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase which was isolated by Michael F. Holick. Physicians worldwide measure this metabolite to determine a patient's vitamin D status.[2] At a typical daily intake of vitamin D3, its full conversion to calcifediol takes approximately 7 days.[3] Calcifediol is then converted in the kidneys (by the enzyme 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the active form of vitamin D. It can also be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.[4][5]. Group: Biochemicals. Alternative Names: ( ε R, 1R, 3aS, 4E, 7aR) -Octahydro-4- [ (2Z) -2- [ (5R) -5-hydroxy-2- methyl enecyclohexylidene] ethylidene] - α , α , ε , 7a-tetra methyl -H-indene-1-pentanol; (3α,5Z,7E)-9,10-Seco-cholesta-5,7,10(19)-triene-3,25-diol; 3-epi-25-Hydroxyvitamin D3. Grades: Highly Purified. CAS No. 73809-05-9. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
3-epi-6-deoxocathasterone 23-monooxygenase
This enzyme is involved in brassinosteroid biosynthesis. C-23 hydroxylation shortcuts bypass campestanol, 6-deoxocathasterone, and 6-deoxoteasterone and lead directly from (22S,24R)-22-hydroxy-5α-ergostan-3-one and 3-epi-6-deoxocathasterone to 3-dehydro-6-deoxoteasterone and 6-deoxotyphasterol. Group: Enzymes. Synonyms: cytochrome P450 90C1; CYP90D1; CYP90C1. Enzyme Commission Number: EC 1.14.13.112. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0712; 3-epi-6-deoxocathasterone 23-monooxygenase; EC 1.14.13.112; cytochrome P450 90C1; CYP90D1; CYP90C1. Cat No: EXWM-0712.
3-hydroxybenzoate 2-monooxygenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is 3-hydroxybenzoate,hydrogen-donor:oxygen oxidoreductase (2-hydroxylating). Other names in common use include 3-hydroxybenzoate 2-hydroxylase, and 3-HBA-2-hydroxylase. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: 3-hydroxybenzoate 2-hydroxylase; 3-HBA-2-hydroxylase. Enzyme Commission Number: EC 1.14.99.23. CAS No. 73507-96-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1041; 3-hydroxybenzoate 2-monooxygenase; EC 1.14.99.23; 73507-96-7; 3-hydroxybenzoate 2-hydroxylase; 3-HBA-2-hydroxylase. Cat No: EXWM-1041.
3-oxoadipate CoA-transferase
This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is succinyl-CoA:3-oxoadipate CoA-transferase. Other names in common use include 3-oxoadipate coenzyme A-transferase, and 3-oxoadipate succinyl-CoA transferase. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: 3-oxoadipate coenzyme A-transferase; 3-oxoadipate succinyl-CoA transferase. Enzyme Commission Number: EC 2.8.3.6. CAS No. 9026-16-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3424; 3-oxoadipate CoA-transferase; EC 2.8.3.6; 9026-16-8; 3-oxoadipate coenzyme A-transferase; 3-oxoadipate succinyl-CoA transferase. Cat No: EXWM-3424.
4-carboxymuconolactone decarboxylase
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: γ-4-carboxymuconolactone decarboxylase; 4-carboxymuconolactone carboxy-lyase; 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming). Enzyme Commission Number: EC 4.1.1.44. CAS No. 37289-46-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4789; 4-carboxymuconolactone decarboxylase; EC 4.1.1.44; 37289-46-6; γ-4-carboxymuconolactone decarboxylase; 4-carboxymuconolactone carboxy-lyase; 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate carboxy-lyase (4,5-dihydro-5-oxofuran-2-acetate-forming). Cat No: EXWM-4789.
4-Ethoxycarbonylphenylboronic acid
4-Ethoxycarbonylphenylboronic acid is used as a reactant in the oxidation of phenol hydroxylation reaction, hydrolysis are aromatic, suzuki - with quinoline carboxylic acid ester coupling reaction, etc. Synonyms: 4-Borono-benzoic Acid 1-Ethyl Ester; p-Borono-benzoic Acid 1-Ethyl Ester; 4-Carboethoxybenzeneboronic Acid; Ethyl 4-Boronobenzoate; MFCD02179441; p-ethoxycarbonylphenylboronic acid; Benzoic acid, 4-borono-, 1-ethyl ester; SCHEMBL5122; KSC489M1F; (4-Ethoxycarbonylphenyl)Boronic Acid; (4-(ethoxycarbonyl)phenyl)boronic acid. Grades: > 98 % (HPLC). CAS No. 4334-88-7. Molecular formula: C9H11BO4. Mole weight: 193.99.
The enzyme, characterized from yeast and mammals, catalyses the hydroxylation of carbon 2 of long- or very-long-chain fatty acids attached to (4R)-4-hydroxysphinganine during de novo ceramide synthesis. The enzymes from yeast and from mammals contain an N-terminal cytochrome b5 domain that acts as the direct electron donor to the desaturase active site. The newly introduced 2-hydroxyl group has R-configuration. cf. EC 1.14.18.7, dihydroceramide fatty acyl 2-hydroxylase. Group: Enzymes. Synonyms: FA2H (gene name); SCS7 (gene name). Enzyme Commission Number: EC 1.14.18.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0968; 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase; EC 1.14.18.6; FA2H (gene name); SCS7 (gene name). Cat No: EXWM-0968.
4-methylphenol dehydrogenase (hydroxylating)
A flavocytochrome c (FAD). Phenazine methosulfate can act as acceptor. A quinone methide is probably formed as intermediate. The first hydroxylation forms 4-hydroxybenzyl alcohol; a second hydroxylation converts this into 4-hydroxybenzaldehyde. Group: Enzymes. Synonyms: p-cresol-(acceptor) oxidoreductase (hydroxylating); p-cresol methylhydroxylase; 4-cresol dehydrogenase (hydroxylating). Enzyme Commission Number: EC 1.17.99.1. CAS No. 66772-07-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1101; 4-methylphenol dehydrogenase (hydroxylating); EC 1.17.99.1; 66772-07-4; p-cresol-(acceptor) oxidoreductase (hydroxylating); p-cresol methylhydroxylase; 4-cresol dehydrogenase (hydroxylating). Cat No: EXWM-1101.
5-epiaristolochene 1,3-dihydroxylase
A heme-thiolate protein (P-450). Kinetic studies suggest that 1β-hydroxyepiaristolochene is mainly formed first followed by hydroxylation at C-3. However the reverse order via 3α-hydroxyepiaristolochene does occur. Group: Enzymes. Synonyms: 5-epi-aristolochene 1,3-dihydroxylase; EAH. Enzyme Commission Number: EC 1.14.13.119. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0719; 5-epiaristolochene 1,3-dihydroxylase; EC 1.14.13.119; 5-epi-aristolochene 1,3-dihydroxylase; EAH. Cat No: EXWM-0719.
7α,27-Dihydroxycholesterol
7α,27-Dihydroxycholesterol is an oxysterol characterized by its oxidized side chains and is produced through the hydroxylation of 27-Hydroxycholesterol (27-OHC); it serves as a metabolite of interest in lipidomic analyses of various pathological conditions, including neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome, and diabetes. Notably, levels of 7α,27-di-OHC decrease following lipopolysaccharide activation, and it also functions as a ligand for Epstein-Barr virus-induced gene 2 (EBI2). Additionally, 7α,27-di-OHC exists as a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC). Uses: Scientific research. Group: Signaling pathways. CAS No. 4725-24-0. Pack Sizes: 1 mg. Product ID: HY-W414548.
Adamantane-d16
Adamantane-d16 is used in the fast catalytic hydroxylation of hydrocarbons with ruthenium porphyrins. Unlabeled adamantane derivatives have been used to treat influenza, as well as serve as NMDA receptor channel blockers for a wide range of pharmaceutical application. Group: Biochemicals. Alternative Names: Tricyclo[3.3.1.13, 7]decane-1, 2, 2, 3, 4, 4, 5, 6, 6, 7, 8, 8, 9, 9, 10, 10-d16; Tricyclo[3.3.1.13, 7]decane-d16; Perdeuteroadamantane. Grades: Highly Purified. CAS No. 30470-60-1. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
aromatase
A cytochrome P-450. The enzyme catalyses three sequential hydroxylations of the androgens androst-4-ene-3,17-dione and testosterone, resulting in their aromatization and forming the estrogens estrone and 17β-estradiol, respectively. The direct electron donor to the enzyme is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: CYP19A1 (gene name); estrogen synthetase (incorrect). Enzyme Commission Number: EC 1.14.14.14. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0911; aromatase; EC 1.14.14.14; CYP19A1 (gene name); estrogen synthetase (incorrect). Cat No: EXWM-0911.
Ascorbic Acid USP (L-Ascorbic acid, Vitamin C)
Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs. Group: Biochemicals. Alternative Names: (+)-Ascorbic Acid; 100M; L-threo-Ascorbic Acid. Grades: Cell Culture Grade. CAS No. 50-81-7. Pack Sizes: 100g, 250g, 500g, 1Kg, 2.5Kg, 5Kg. US Biological Life Sciences.
Worldwide
aureusidin synthase
A copper-containing glycoprotein that plays a key role in the yellow coloration of flowers such as Antirrhinum majus (snapdragon). The enzyme is a homologue of plant polyphenol oxidase and catalyses two separate chemical transformations, i.e. 3-hydroxylation and oxidative cyclization (2',-dehydrogenation). H2O2 activates reaction (1) but inhibits reaction (2). Originally considered to act on the phenol but now thought to act mainly on the 4'-O-β-D-glucoside in vivo. Group: Enzymes. Synonyms: AmAS1. Enzyme Commission Number: EC 1.21.3.6. CAS No. 320784-48-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1253; aureusidin synthase; EC 1.21.3.6; 320784-48-3; AmAS1. Cat No: EXWM-1253.
benzaldehyde dehydrogenase (NAD+)
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is benzaldehyde:NAD+ oxidoreductase. Other names in common use include benzaldehyde (NAD+) dehydrogenase, and benzaldehyde dehydrogenase (NAD+). This enzyme participates in benzoate degradation via hydroxylation and toluene and xylene degradation. Group: Enzymes. Synonyms: benzaldehyde (NAD) dehydrogenase; benzaldehyde dehydrogenase (NAD). Enzyme Commission Number: EC 1.2.1.28. CAS No. 37250-93-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1134; benzaldehyde dehydrogenase (NAD+); EC 1.2.1.28; 37250-93-4; benzaldehyde (NAD) dehydrogenase; benzaldehyde dehydrogenase (NAD). Cat No: EXWM-1134.
benzaldehyde dehydrogenase (NADP+)
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is benzaldehyde:NADP+ oxidoreductase. Other names in common use include NADP+-linked benzaldehyde dehydrogenase, and benzaldehyde dehydrogenase (NADP+). This enzyme participates in benzoate degradation via hydroxylation and toluene and xylene degradation. Group: Enzymes. Synonyms: NADP-linked benzaldehyde dehydrogenase; benzaldehyde dehydrogenase (NADP). Enzyme Commission Number: EC 1.2.1.7. CAS No. 9028-89-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1171; benzaldehyde dehydrogenase (NADP+); EC 1.2.1.7; 9028-89-1; NADP-linked benzaldehyde dehydrogenase; benzaldehyde dehydrogenase (NADP). Cat No: EXWM-1171.
Bufuralol hydrochloride
Bufuralol (Ro-34787) is a β-adrenoceptor blocker with partial peripheral vasodilating activity and is potentially useful for the treatment of hypertension. It is primarily metabolized by cytochrome P450 (CYP) isoform CYP2D6, with CYP1A2 and CYP2C19 also contributing to 1'-hydroxylation. Most beta blockers are aryloxypropanolamine-based, in this rare exception, the benzofuran oxygen is part of a ring instead of derived from the epichlorohydrin precursor. Synonyms: Ro 3-4787. Grades: ≥95%. CAS No. 60398-91-6. Molecular formula: C16H23NO2·HCl. Mole weight: 297.8.
Bupropion Morpholinol
Bupropion Morpholinol is a major metabolite of the dopamine transport inhibitor and nicotinic antagonist bupropion. It is formed by hydroxylation of bupropion on the tert-butyl group and cyclizes to an acetal. It is a racemic preparation of the R,R-hydroxy bupropion and S,S-hydroxy bupropion isomers. Synonyms: Hydroxy Bupropion, Mixture of Stereoisomers; 2-(3-Chlorophenyl)-3,5,5-triMethyl-; 2-Hydroxy-2-(3'-chlorophenyl)-3,5,5-trimethylmorpholine. Grades: > 95%. CAS No. 357399-43-0. Molecular formula: C13H18ClNO2. Mole weight: 255.75.
Calcifediol-d6
A metabolite of Vitamin D. The principal circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Calcium regulator. Group: Biochemicals. Alternative Names: (3 β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol-d6; 25-Hydroxycholecalciferol-d6; 25-Hydroxyvitamin D-d6; 25-Hydroxyvitamin D3-d6; Calcidiol-d6; Didrogyl-d6; Hidroferol-d6; Ro 8-8892-d6. Grades: Highly Purified. CAS No. 78782-98-6. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Calcifediol monohydrate
Calcifediol monohydrate is a prehormone that is produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme cholecalciferol 25-hydroxylase. It can be converted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation. Uses: Bone density conservation agents. Synonyms: 25-hydroxy Vitamin D3 monohydrate. Grades: >98%. CAS No. 63283-36-3. Molecular formula: C27H46O3. Mole weight: 418.65.
Calcioic Acid
Calcioic Acid is the end product of metabolism of Calcifediol (C125700), which is a metabolite of Vitamin D. Calcifedio is the main circulating form of vitamin D3, formed in the liver by hydroxylation at C-25. Group: Biochemicals. Grades: Highly Purified. CAS No. 76794-34-8. Pack Sizes: 100ug, 250ug. Molecular Formula: C23H34O3, Molecular Weight: 358.51. US Biological Life Sciences.
Worldwide
Calcium Ascorbate Dihydrate
Calcium Ascorbate Dihydrate is a salt of Ascorbic Acid (A786990), physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs. Group: Biochemicals. Grades: Highly Purified. CAS No. 5743-28-2. Pack Sizes: 1g, 5g. Molecular Formula: C12H14O12Ca 2[H2O], Molecular Weight: 426.36. US Biological Life Sciences.
Worldwide
Calcium Ascorbate Dihydrate
Calcium Ascorbate Dihydrate is a salt of Ascorbic Acid, physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs. Synonyms: L-Ascorbic Acid Calcium Salt Hydrate; L-Ascorbic Acid Calcium Salt Dihydrate; Calcium L-Ascorbate Dihydrate; Calcium Ascorbate Dihydrate. Grades: 98%. CAS No. 5743-28-2. Molecular formula: C12H14O12Ca 2(H2O). Mole weight: 426.36.
Calcium L-ascorbate dihydrate
Calcium L-ascorbate dihydrate, commonly called vitamin C calcium salt, is a biologically important antioxidant and a required coenzyme for various hydroxylation reactions and for collagen synthesis. Applications: A physiological antioxidant and coenzyme. Group: Coenzymes. Synonyms: L-Ascorbic acid calcium salt dihydrate; Vitamin C calcium salt. CAS No. 5743-28-2. Mole weight: 426.34. Appearance: Powder. Form: Solid. L-Ascorbic acid calcium salt dihydrate; Vitamin C calcium salt; Calcium L-ascorbate dihydrate; 5743-28-2. Cat No: COEC-049.
carboxy-cis,cis-muconate cyclase
This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: 3-carboxymuconate cyclase; 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.5. CAS No. 37318-55-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5631; carboxy-cis,cis-muconate cyclase; EC 5.5.1.5; 37318-55-1; 3-carboxymuconate cyclase; 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). Cat No: EXWM-5631.
Cedrol
Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes. Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, insecticidal, and anti-fungal activities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cypress camphor. Product Category: Inhibitors. Appearance: Pale yellow to yellow green solid. CAS No. 77-53-2. Molecular formula: C15H26O. Mole weight: 222.37. Purity: 0.99. IUPACName: (1S,2R,5S,7R,8R)-2,6,6,8-Tetramethyltricyclo[5.3.1.01,5]undecan-8-ol. Canonical SMILES: CC1CCC2C13CCC(C(C3)C2(C)C)(C)O. Density: 0.9479 g/cm³. Product ID: ACM77532. Alfa Chemistry ISO 9001:2015 Certified.
Chlorohydroquinone (Technical Grade, ~90%)
Chlorohydroquinone is a component of polyethers based on organotin with potential application to breast cancer treatment via growth inhibition. Also a component in the synthesis of contraceptive agents in pharmaceutical compounds. It is also used within hydroxylation and catalysis organic reactions in the synthesis of pharmacologically active phenolic compounds. Group: Biochemicals. Alternative Names: Chloroquinol; Monochloro hydroquinone; NSC 427; NSC 5934; 1,4-Dihydroxy-2-chlorobenzene; 1-Chloro-2,5-dihydroxybenzene; 2-Chloro-1,4-benzenediol; 2-Chloro-1,4-dihydroxybenzene; 2-Chloro-1,4-hydroquinone; 2-Chlorohydroquinone; Chloro-p-hydroquinone. Grades: Purified. CAS No. 615-67-8. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
chlorophyllide-a oxygenase
Chlorophyll b is required for the assembly of stable light-harvesting complexes (LHCs) in the chloroplast of green algae, cyanobacteria and plants. Contains a mononuclear iron centre. The enzyme catalyses two successive hydroxylations at the 7-methyl group of chlorophyllide a. The second step yields the aldehyde hydrate, which loses H2O spontaneously to form chlorophyllide b. Chlorophyll a and protochlorophyllide a are not substrates. Group: Enzymes. Synonyms: chlorophyllide a oxygenase; chlorophyll-b synthase; CAO. Enzyme Commission Number: EC 1.14.13.122. CAS No. 216503-73-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0723; chlorophyllide-a oxygenase; EC 1.14.13.122; 216503-73-0; chlorophyllide a oxygenase; chlorophyll-b synthase; CAO. Cat No: EXWM-0723.
This enzyme, found in several bacterial pathogens, is involved in degradation of the host cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25R) conformation. The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.141, cholest-4-en-3-one 26-monooxygenase. The enzyme can receive electrons from ferredoxin reductase in vitro, its natural electron donor is not known yet. Group: Enzymes. Synonyms: CYP142. Enzyme Commission Number: EC 1.14.13.221. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0824; cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.221; CYP142. Cat No: EXWM-0824.
This enzyme, found in several bacterial pathogens, is involved in degradation of the host's cholesterol. It catalyses the hydroxylation of the C-26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate, initiating the degradation of the alkyl side-chain of cholesterol. The products are exclusively in the (25S) configuration. It is a two-component system consisting of a P-450 (heme thiolate) oxygenase (Cyp125) and a ferredoxin reductase (most likely KshB, which is also a part of EC 1.14.13.142, 3-ketosteroid 9α-monooxygenase). The enzyme also accepts cholesterol as a substrate. cf. EC 1.14.13.221, cholest-4-en-3-one 27-monooxygenase. Group: Enzymes. Synonyms: CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxyl. Enzyme Commission Number: EC 1.14.13.141. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0741; cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]; EC 1.14.13.141; CYP125; CYP125A1; cholest-4-en-3-one 27-monooxygenase (misleading); cholest-4-en-3-one,NADH:oxygen oxidoreductase (26-hydroxylating); cholest-4-en-3-one 26-monooxygenase (ambiguous). Cat No: EXWM-0741.
cholesterol 25-hydroxylase
Unlike most other sterol hydroxylases, this enzyme is not a cytochrome P-450. Instead, it uses diiron cofactors to catalyse the hydroxylation of hydrophobic substrates. The diiron cofactor can be either Fe-O-Fe or Fe-OH-Fe and is bound to the enzyme through interactions with clustered histidine or glutamate residues. In cell cultures, this enzyme down-regulates cholesterol synthesis and the processing of sterol regulatory element binding proteins (SREBPs). Group: Enzymes. Synonyms: cholesterol 25-monooxygenase. Enzyme Commission Number: EC 1.14.99.38. CAS No. 60202-07-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1049; cholesterol 25-hydroxylase; EC 1.14.99.38; 60202-07-5; cholesterol 25-monooxygenase. Cat No: EXWM-1049.
Cholesterol-25-Hydroxylase, Human (CH25H)
Cholesterol-25-Hydroxylase (CH25H) is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. Group: Molecular Biology. Pack Sizes: 10ug, 50ug, 100ug. US Biological Life Sciences.
Worldwide
cholesterol monooxygenase (side-chain-cleaving)
A heme-thiolate protein (cytochrome P-450). The reaction proceeds in three stages, with two hydroxylations at C-22 and C-20 preceding scission of the side-chain between carbons 20 and 22. The initial source of the electrons is NADPH, which transfers the electrons to the adrenodoxin via EC 1.18.1.6, adrenodoxin-NADP+ reductase. Group: Enzymes. Synonyms: cholesterol desmolase; cytochrome P-450scc; C27-side chain cleavage enzyme; cholesterol 20-22-desmolase; cholesterol C20-22 desmolase; cholesterol side-chain cleavage enzyme; cholesterol side-chain-cleaving enzyme; steroid 20-22 desmolase; steroid 20-22-lyase; CYP11A1 (gene name). Enzyme Commission Number: EC 1.14.15.6. CAS No. 37292-81-2, 440354-98-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0949; cholesterol monooxygenase (side-chain-cleaving); EC 1.14.15.6; 37292-81-2, 440354-98-3; cholesterol desmolase; cytochrome P-450scc; C27-side chain cleavage enzyme; cholesterol 20-22-desmolase; cholesterol C20-22 desmolase; cholesterol side-chain cleavage enzyme; cholesterol side-chain-cleaving enzyme; steroid 20-22 desmolase; steroid 20-22-lyase; CYP11A1 (gene name). Cat No: EXWM-0949.
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