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Also acts on 3-(3,4-dihydroxyphenyl)lactate. Involved with EC 2.3.1.140 rosmarinate synthase in the biosynthesis of rosmarinic acid. Group: Enzymes. Synonyms: HPRP. Enzyme Commission Number: EC 1.1.1.237. CAS No. 117590-77-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0144; hydroxyphenylpyruvate reductase; EC 1.1.1.237; 117590-77-9; HPRP. Cat No: EXWM-0144.
The enzyme is involved in the biosynthesis of the 3-dimethylallyl-4-hydroxyphenylpyruvate moiety of the aminocoumarin antibiotics clorobiocin and novobiocin. Group: Enzymes. Synonyms: CloQ; 4HPP dimethylallyltransferase; NovQ. Enzyme Commission Number: EC 2.5.1.111. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2727; 4-hydroxyphenylpyruvate 3-dimethylallyltransferase; EC 2.5.1.111; CloQ; 4HPP dimethylallyltransferase; NovQ. Cat No: EXWM-2727.
4-hydroxyphenylpyruvate decarboxylase
Reacts with dopamine to give the benzylisoquinoline alkaloid skeleton. Group: Enzymes. Synonyms: 4-hydroxyphenylpyruvate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.80. CAS No. 109300-96-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4829; 4-hydroxyphenylpyruvate decarboxylase; EC 4.1.1.80; 109300-96-1; 4-hydroxyphenylpyruvate carboxy-lyase. Cat No: EXWM-4829.
4-hydroxyphenylpyruvate dioxygenase
The Pseudomonas enzyme contains one Fe3+ per mole of enzyme; the enzymes from other sources may contain essential iron or copper. Group: Enzymes. Synonyms: p-hydroxyphenylpyruvic hydroxylase; p-hydroxyphenylpyruvate hydroxylase; p-hydroxyphenylpyruvate oxidase; p-hydroxyphenylpyruvic oxidase; p-hydroxyphenylpyruvate dioxygenase; p-hydroxyphenylpyruvic acid hydroxylase; 4-hydroxyphenylpyruvic acid dioxygenase. Enzyme Commission Number: EC 1.13.11.27. CAS No. 9029-72-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0546; 4-hydroxyphenylpyruvate dioxygenase; EC 1.13.11.27; 9029-72-5; p-hydroxyphenylpyruvic hydroxylase; p-hydroxyphenylpyruvate hydroxylase; p-hydroxyphenylpyruvate oxidase; p-hydroxyphenylpyruvic oxidase; p-hydroxyphenylpyruvate dioxygenase; p-hydroxyphenylpyruvic acid hydroxylase; 4-hydroxyphenylpyruvic acid dioxygenase. Cat No: EXWM-0546.
4-hydroxyphenylpyruvate oxidase
Involved in tyrosine degradation pathway in Arthrobacter sp. Group: Enzymes. Enzyme Commission Number: EC 1.2.3.13. CAS No. 78213-74-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1207; 4-hydroxyphenylpyruvate oxidase; EC 1.2.3.13; 78213-74-8. Cat No: EXWM-1207.
1-Cyano-6-(methylsulfonyl)-7-nitro-9H-xanthen-9-one is an impurity of Mesotrione (M225765), a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of lepospermone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C15H8N2O6S. US Biological Life Sciences.
Worldwide
1-Cyano-6-(methylsulfonyl)-9H-xanthen-9-one
1-Cyano-6-(methylsulfonyl)-9H-xanthen-9-one is a related compound of Mesotrione (M225765), a herbicide that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C15H9NO4S, Molecular Weight: 299.3. US Biological Life Sciences.
2-Bromo-6- (3- (methylsulfonyl) -4-nitrophenoxy) benzaldehyde is an intermediate in the synthesis of 1-Cyano-6-(methylsulfonyl)-7-nitro-9H-xanthen-9-one (C981885), which is an impurity of Mesotrione (M225765), a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of lepospermone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C14H10BrNO6S. US Biological Life Sciences.
Worldwide
3, 5-Dioxocyclohexane carboxylic Acid Ethyl Ester
A reactant in the preparation of plant growth retardants and cyclopropane carbonyloxy cyclohexenone derivs. as hydroxyphenylpyruvate dioxygenase inhibitors. Group: Biochemicals. Alternative Names: Ethyl 3, 5-Dioxocyclohexane carboxylate. Grades: Highly Purified. CAS No. 27513-35-5. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
3- (Trifluoromethoxy) aniline
3- (Trifluoromethoxy) aniline is reactant in the synthesis of pyrazolone-quinazolone hybrids as human hydroxyphenylpyruvate dioxygenase inhibitors which is a potential treatment for type I tyrosinemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 1535-73-5. Pack Sizes: 1g, 10g. Molecular Formula: C7H6F3NO. US Biological Life Sciences.
Worldwide
4-hydroxymandelate synthase
Requires Fe2+. Involved in the biosynthesis of the vancomycin group of glycopeptide antibiotics. Group: Enzymes. Synonyms: 4-hydroxyphenylpyruvate dioxygenase II. Enzyme Commission Number: EC 1.13.11.46. CAS No. 280566-04-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0564; 4-hydroxymandelate synthase; EC 1.13.11.46; 280566-04-3; 4-hydroxyphenylpyruvate dioxygenase II. Cat No: EXWM-0564.
Binds a [4Fe-4S] cluster. The cluster is coordinated by 3 cysteines and an exchangeable AdoMet molecule. The first stage of catalysis is reduction of the 2 AdoMet to produce 2 methionine and 2 5'-deoxyadenosin-5-yl radicals that extract a hydrogen from each of the substrates permitting the condensation of the two. The overall reaction catalysed is the transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylaminopyrimidine-2,4(1H,3H)-dione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO). 7,8-Didemethyl-8-hydroxy-5-deazariboflavin is the chromophore of the hydride carrier coenzyme F420. Group: Enzymes. Synonyms: FO synthase. Enzyme Commission Number: EC 2.5.1.77. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2815; 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; EC 2.5.1.77; FO synthase. Cat No: EXWM-2815.
Adamantoic Acid
Adamantoic Acid is an inhibitor of chorismate mutase activity and hydroxyphenylpyruvate synthase. It inhibits TTR conformational changes facilitating amyloid fibril formation. Group: Biochemicals. Alternative Names: 1-Adamantanecarboxylic Acid; 1-Adamantane-1-carboxylic Acid; 1-Adamantylcarboxylic Acid; 1-Carboxyadamantane; NSC 94182; Tricyclo[3.3.1.13, 7]decane-1-carboxylic Acid. Grades: Highly Purified. CAS No. 828-51-3. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
chorismate mutase
In enzymology, a chorismate mutase (EC 5.4.99.5) is an enzyme that catalyzes the chemical reaction for the conversion of chorismate to prephenate in the pathway to the production of phenylalanine and tyrosine, also known as the shikimate pathway. Group: Enzymes. Synonyms: hydroxyphenylpyruvate synthase. Enzyme Commission Number: EC 5.4.99.5. CAS No. 9068-30-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5592; chorismate mutase; EC 5.4.99.5; 9068-30-8; hydroxyphenylpyruvate synthase. Cat No: EXWM-5592.
glutamate-prephenate aminotransferase
A pyridoxal-phosphate protein. Aspartate can also act as the amino donor, but more slowly (cf. EC 2.6.1.78, aspartate-prephenate aminotransferase). The enzyme from higher plants shows a marked preference for prephenate as substrate compared to pyruvate, phenylpyruvate or 4-hydroxyphenylpyruvate. Group: Enzymes. Synonyms: prephenate transaminase (ambiguous); PAT (ambiguous); L-glutamate:prephenate aminotransferase. Enzyme Commission Number: EC 2.6.1.79. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2919; glutamate-prephenate aminotransferase; EC 2.6.1.79; prephenate transaminase (ambiguous); PAT (ambiguous); L-glutamate:prephenate aminotransferase. Cat No: EXWM-2919.
HPPD-IN-3
HPPD-IN-3 (compound 25) is a potent inhibitor of 4-Hydroxyphenylpyruvate dioxygenase ( HPPD ), with IC 50 of 10 nM, more potency than Mesotrione (HY-12853) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3024245-46-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161308.
indolepyruvate ferredoxin oxidoreductase
Contains thiamine diphosphate and [4Fe-4S] clusters. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and p-hydroxyphenylpyruvate as substrates. This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity. For examples of other members of this family, see EC 1.2.7.3, 2-oxoglutarate synthase and EC 1.2.7.7, 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin). Group: Enzymes. Synonyms: 3-(indol-3-yl)pyruvate synthase (ferredoxin); IOR. Enzyme Commission Number: EC 1.2.7.8. CAS No. 158886-06-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1231; indolepyruvate ferredoxin oxidoreductase; EC 1.2.7.8; 158886-06-7; 3-(indol-3-yl)pyruvate synthase (ferredoxin); IOR. Cat No: EXWM-1231.
Isoxaflutole
Isoxaflutole (Merlin; RP-201772) is a selective herbicide for pre-emergence control of a wide range of important broadleaf and grass weeds in corn and sugarcane. Isoxaflutole is a precursor and delivery vector of diketonitrile (DKN), which is an inhibitor for 4-hydroxyphenylpyruvate dioxygenase ( HPPD ), leads to a characteristic bleaching of susceptible species [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Merlin; RP-201772. CAS No. 141112-29-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116139.
Leptospermone
Leptospermone is a competitive, reversible inhibitor for p-Hydroxyphenylpyruvate dioxygenase ( HPPD ), with an IC 50 of 12.1 μM. Leptospermone exhibits herbicidal activity for its bleaching effect [1]. Uses: Scientific research. Group: Natural products. CAS No. 567-75-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114991.
Native Bovine Tautomerase
In enzymology, phenylpyruvate tautomerase or Macrophage migration inhibitory factor (EC 5.3.2.1) is an enzyme that catalyzes the chemical reaction:keto-phenylpyruvate<-> enol-phenylpyruvate. Phenylpyruvate tautomerase has also been found to exhibit the same keto-enol tautomerism for 4-Hydroxyphenylpyruvic acid, which is structurally similar to phenylpyruvate but contains an additional hydroxyl moiety in the para position of the aromatic ring. This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting keto-and enol-groups. This enzyme participates in tyrosine metabolism and phenylalanine metabolism. Applications: Tautomerase from bovine kidney has been used in a study to assess tritium isotope effects in the reaction catalyzed by 4-hydroxyphenylpyruvate dioxygenase. tautomerase from bovine kidney has also been used in a study to investigate human macrophage migration inhibitory factor. Group: Enzymes. Synonyms: Tautomerase; phenylpyruvate tautomerase; EC 5.3.2.1; phenylpyruvic keto-. Enzyme Commission Number: EC 5.3.2.1. CAS No. 9023-54-5. Tautomerase. Activity: 1-4 units/mg protein (Lowry), ~10 units/mL. Storage: -20°C. Form: aqueous solution. Source: Bovine kidney. Species: Bovine. Tautomerase; phenylpyruvate tautomerase; EC 5.3.2.1; phenylpyruvic keto-enol isomerase; 9023-54-5. Cat No: NATE-0691.
Nitisinone
Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I. Group: Biochemicals. Alternative Names: 2-[2-Nitro-4- (trifluoromethyl) benzoyl]-. Grades: Highly Purified. CAS No. 104206-65-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Nitisinone
Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase ( 4-HPPD ) inhibitor with an IC 50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NTBC; Nitisone; SC0735. CAS No. 104206-65-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0607.
Nitisinone
Nitisinone(SC0735) is an inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase. Uses: Enzyme inhibitors. Synonyms: 2-[2-Nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione; NTBC; Nitisone. Grades: >98%. CAS No. 104206-65-7. Molecular formula: C14H10F3NO5. Mole weight: 329.23.
Nitisinone-13C6
Labeled Nitisinone. Nitisinone is a herbicidal triketone that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), an enzyme involved in plastoquinone biosynthesis in plants and in tyrosine catabolism in mammals. It is used in treatment of inherited tyrosinemia type I. Group: Biochemicals. Alternative Names: 2-[2-Nitro-4- (trifluoromethyl) benzoyl]-. Grades: Highly Purified. CAS No. 1246815-63-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
prephenate dehydrogenase
This enzyme in the enteric bacteria also possesses chorismate mutase activity (EC 5.4.99.5 chorismate mutase) and converts chorismate into prephenate. Group: Enzymes. Synonyms: hydroxyphenylpyruvate synthase; chorismate mutase-prephenate dehydrogenase. Enzyme Commission Number: EC 1.3.1.12. CAS No. 9044-92-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1286; prephenate dehydrogenase; EC 1.3.1.12; 9044-92-2; hydroxyphenylpyruvate synthase; chorismate mutase-prephenate dehydrogenase. Cat No: EXWM-1286.
rosmarinate synthase
Involved, with EC 1.1.1.237 (hydroxyphenylpyruvate reductase) in the biosynthesis of rosmarinic acid. Characterized from the plant Melissa officinalis L. (lemon balm). Group: Enzymes. Synonyms: rosmarinic acid synthase; caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase; 4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase; RAS (gene name). Enzyme Commission Number: EC 2.3.1.140. CAS No. 117590-80-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2079; rosmarinate synthase; EC 2.3.1.140; 117590-80-4; rosmarinic acid synthase; caffeoyl-coenzyme A:3,4-dihydroxyphenyllactic acid caffeoyltransferase; 4-coumaroyl-CoA:4-hydroxyphenyllactic acid 4-coumaroyl transferase; RAS (gene name). Cat No: EXWM-2079.
Sulcotrione
Sulcotrione is a β-triketone herbicide which can inhibit hydroxyphenylpyruvate dioxygenase ( HPPD ). Uses: Scientific research. Group: Signaling pathways. CAS No. 99105-77-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-107368.
3,5-Diiodo-4-hydroxyphenylpyruvic acid
3,5-Diiodo-4-hydroxyphenylpyruvic acid. Group: Biochemicals. Alternative Names: (4-Hydroxy-3,5-diiodophenyl)pyruvic acid. Grades: Highly Purified. CAS No. 780-00-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C9H6I2O4. US Biological Life Sciences.
3,5-Diiodo-4-hydroxyphenylpyruvic Acid ((4-Hydroxy-3,5-diiodophenyl)pyruvic Acid). Group: Biochemicals. Alternative Names: (4-Hydroxy-3,5-diiodophenyl)pyruvic Acid. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
4-?Hydroxyphenylpyruvic acid
4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine. Uses: Scientific research. Group: Natural products. CAS No. 156-39-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W010040.
4-Hydroxyphenylpyruvic acid
4-Hydroxyphenylpyruvic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 156-39-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Hydroxyphenylpyruvic acid
Hydroxyphenylpyruvic acid. CAS No: 156-39-8
Sarchem Laboratories New Jersey NJ
tyrosine transaminase
A pyridoxal-phosphate protein. L-Phenylalanine can act instead of L-tyrosine. The mitochondrial enzyme may be identical with EC 2.6.1.1 (aspartate transaminase). The three isoenzymic forms are interconverted by EC 3.4.22.32 (stem bromelain) and EC 3.4.22.33 (fruit bromelain). The enzyme can also catalyse the final step in the methionine-salvage pathway of Klebsiella pneumoniae. Group: Enzymes. Synonyms: tyrosine aminotransferase; glutamic-hydroxyphenylpyruvic transaminase; glutamic phenylpyruvic aminotransferase; L-phenylalanine 2-oxoglutarate aminotransferase; L-tyrosine aminotransferase; phenylalanine. Enzyme Commission Number: EC 2.6.1.5. CAS No. 9014-55-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2891; tyrosine transaminase; EC 2.6.1.5; 9014-55-5; tyrosine aminotransferase; glutamic-hydroxyphenylpyruvic transaminase; glutamic phenylpyruvic aminotransferase; L-phenylalanine 2-oxoglutarate aminotransferase; L-tyrosine aminotransferase; phenylalanine aminotransferase; phenylalanine transaminase; phenylalanine-α-ketoglutarate transaminase; phenylpyruvate transaminase; phenylpyruvic acid transaminase; tyrosine-α-ketoglutarate aminotransferase; tyrosine-α-ketoglutarate transaminase; tyrosine-2-ketoglutarate aminotransferase; TyrAT. Cat No: EXWM-2891.
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