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25g Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C5H4N4O. CAS No. 68-94-0. Prepack ID 46877163-25g. Molecular Weight 136.11. See USA prepack pricing.
Hypoxanthine
Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia. Uses: Scientific research. Group: Natural products. Alternative Names: Purin-6-ol; Sarcine. CAS No. 68-94-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0091.
Hypoxanthine-13c2,15N
Heterocyclic Organic Compound. Alternative Names: 1,9-Dihydro-. CAS No. 1246820-04-1. Molecular formula: C313C2H4N315NO. Mole weight: 139.09. Appearance: White Solid. Catalog: ACM1246820041.
Hypoxanthine-13C2,15N
A metabolite of Purine in cocaine addiction. Group: Biochemicals. Alternative Names: 1,9-Dihydro-. Grades: Highly Purified. CAS No. 1246820-04-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Hypoxanthine (6-Hydroxypurine)
Hypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies. Group: Biochemicals. Alternative Names: 1,9-Dihydro-6H-purin-6-one; 3H-Purin-6-ol; 6-Hydroxy-1H-purine; 6-Hydroxypurine; 6-Oxopurine; Hypoxanthine enol; NSC 129419; NSC 14665; Purin-6-ol; Sarcine; Sarkin; Sarkine; USP Didanosine Related Compound A. Grades: Highly Purified. CAS No. 68-94-0. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C5H4N4O, Molecular Weight: 136.11. US Biological Life Sciences.
Worldwide
Hypoxanthine 99+% (HPLC) (6-Hydroxypurine)
Hypoxanthine 99+% (HPLC) (6-Hydroxypurine). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
Hypoxanthine-guanine phosphoribosyltransferase from Human, Recombinant
HGPRT is a highly active enzyme that catalyzes the reversible transfer of the 5-phosphoribosyl group between α-D-5-phosphoribosyl-1-pyrophosphate (PRPP) and a purine base (hypoxanthine or guanine) to form a purine nucleotide IMP or GMP. The enzyme has been characterized for its affinity for natural substrates and velocity in forward and reverse directions. Group: Enzymes. Synonyms: Hypoxanthine phosphoribosyltransferase; HGPRTase; HPRT; Hypoxanthine-guanine phosphoribosyltransferase; HGPRT; EC 2.4.2.8. Enzyme Commission Number: EC 2.4.2.8. CAS No. 9016-12-0. HGPRT. Mole weight: 25kDa. Activity: > 1 Unit/mg protein. Storage: HPRT enzyme is provided in lyophilized form and should be stored at -20°C. Source: E. coli. Species: Human. Hypoxanthine phosphoribosyltransferase; HGPRTase; HPRT; Hypoxanthine-guanine phosphoribosyltransferase; HGPRT; EC 2.4.2.8. Cat No: NATE-1166.
Guanine and 6-mercaptopurine can replace hypoxanthine. Group: Enzymes. Synonyms: IMP pyrophosphorylase; transphosphoribosidase; hypoxanthine-guanine phosphoribosyltransferase; guanine phosphoribosyltransferase; GPRT; HPRT; guanosine 5'-phosphate pyrophosphorylase; IMP-GMP pyrophosphorylase; HGPRTase; 6-hydroxypurine phosphoribosyltransferase; 6-mercaptopurine phosphoribosyltransferas. Enzyme Commission Number: EC 2.4.2.8. CAS No. 9016-12-0. HGPRT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2691; hypoxanthine phosphoribosyltransferase; EC 2.4.2.8; 9016-12-0; IMP pyrophosphorylase; transphosphoribosidase; hypoxanthine-guanine phosphoribosyltransferase; guanine phosphoribosyltransferase; GPRT; HPRT; guanosine 5'-phosphate pyrophosphorylase; IMP-GMP pyrophosphorylase; HGPRTase; 6-hydroxypurine phosphoribosyltransferase; 6-mercaptopurine phosphoribosyltransferase; GMP pyrophosphorylase; guanine-hypoxanthine phosphoribosyltransferase; guanosine phosphoribosyltransferase; guanylate pyrophosphorylase; guanylic pyrophosphorylase; inosinate pyrophosphorylase; inosine 5'-phosphate pyrophosphorylase; inosinic acid pyrophosphorylase; inosinic pyrophosphorylase; 6-mercaptopurine phosphoribosyltransferase; purine-6-thiol phosphoribosyltransferase. Cat No: EXWM-2691.
2-Aza-8-oxo-hypoxanthine
2-Aza-8-oxo-hypoxanthine is a pharmaceutically active agent used to regulate cartenoid accumulation in citris juice sacs. It functions as a fairy-ring plant growth regulator. Group: Biochemicals. Grades: Highly Purified. CAS No. 1403820-30-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C4H3N5O2, Molecular Weight: 153.1. US Biological Life Sciences.
Worldwide
2'-Fluoro-2'-deoxy-arabinofuranosyl-hypoxanthine
2'-Fluoro-2'-deoxy-arabinofuranosyl-hypoxanthine is an efficacious antiviral compound, carefully and decisively thwarts the replication of viral DNA by vehemently interrupting the research and development of viral DNA. Synonyms: 2'-FANA-I; 9-(2'-Fluoro-2'-deoxy-β-D-arabinofuranosyl)hypoxanthine. Grades: ≥ 97%. Molecular formula: C10H11FN4O4. Mole weight: 270.22.
7-Deaza-2-mercapto-hypoxanthine
7-Deaza-2-mercapto-hypoxanthine. Group: Biochemicals. Alternative Names: 7-Deaza-6-hydroxy-2-mercaptopurine; 2-Thioxo-7-deazahypoxanthine; NSC 25976. Grades: Highly Purified. CAS No. 67831-84-9. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C6H5N3OS. US Biological Life Sciences.
7-Deaza-2-mercapto-hypoxanthine (7-Deaza-6-hydroxy-2-mercaptopurine). Group: Biochemicals. Alternative Names: 7-Deaza-6-hydroxy-2-mercaptopurine. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
9- (b-D-Arabinofuranosyl) hypoxanthine
9- (b-D-Arabinofuranosyl) hypoxanthine. Group: Biochemicals. Alternative Names: Arabinofuranosyl-hypoxanthine. Grades: Highly Purified. CAS No. 7013-16-3. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C10H12N4O5. US Biological Life Sciences.
Worldwide
Arabinofuranosyl-hypoxanthine (ara-HX)
Arabinofuranosyl-hypoxanthine (ara-HX) is a prodrug of Vidarabine for improving the oral bioavailability, which is an antiviral drug. Uses: Antiviral agents. Synonyms: Hypoxanthine arabinoside; 9-(β-D-Arabinofuranosyl)-hypoxanthine; 9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one; 9-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one. Grades: ≥ 99%. CAS No. 7013-16-3. Molecular formula: C10H12N4O5. Mole weight: 268.22.
2'-Amino-2'-deoxyinosine
2'-Amino-2'-deoxyinosine. Group: Biochemicals. Alternative Names: 9-(2-Amino-2-deoxy-b-D-ribofuranosyl)-hypoxanthine. Grades: Highly Purified. CAS No. 75763-51-8. Pack Sizes: 100mg, 500mg, 1g, 2g, 5g. Molecular Formula: C10H13N5O4. US Biological Life Sciences.
Worldwide
2'-Deoxy-2'-fluoroarabinoinosine
2'-Deoxy-2'-fluoroarabinoinosine is a nucleoside analog used in the treatment of viral infections such as hepatitis C and B. It exhibits potent antiviral activity by inhibiting viral RNA synthesis and acting as a chain terminator during viral genome replication. It has also been studied for its potential use in cancer treatment due to its ability to interfere with DNA synthesis. Synonyms: 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one; 9-(2-Deoxy-2-fluoro-D-arabinofuranosyl)hypoxanthine; 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-ol. Grades: ≥95%. CAS No. 98983-40-5. Molecular formula: C10H11FN4O4. Mole weight: 270.22.
2'-Deoxy-2'-fluoroinosine
2'-Deoxy-2'-fluoroinosine. Group: Biochemicals. Alternative Names: 2'-Fluoro-2'-deoxy-D-inosine; 9-(2-FIuoro-2-deoxy-b-D-ribofuranosyI)-hypoxanthine. Grades: Highly Purified. CAS No. 80049-87-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C10H11FN4O4. US Biological Life Sciences.
Worldwide
2'-Deoxyinosine
An Inosine analog with hypotensive activity. An impurity of the antiviral drug 2,3-Dideoxyinosine. Group: Biochemicals. Alternative Names: 1,9-Dihydro-9-(2-deoxy- β-D-ribofuranosyl)-6H-purin-6-one; 9-(2-Deoxy- β-D-erythro-pentofuranosyl)-1,9-dihydro-6H-purin-6-one; Hypoxanthine Deoxyriboside. Grades: Highly Purified. CAS No. 890-38-0. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
2'-Deoxyinosine
It is an inosine analogue with hypotensive activity and an impurity of the antiviral drug 2',3'-dideoxyinosine. Synonyms: 1,9-Dihydro-9-(2'-deoxy-β-D-ribofuranosyl)-6H-purin-6-one; 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-1,9-dihydro-6H-purin-6-one; Hypoxanthine Deoxyriboside; Didanosine EP Impurity C; 9-(2-Deoxy-beta-D-ribofuranosyl)hypoxanthine. Grades: ≥ 95 %. CAS No. 890-38-0. Molecular formula: C10H12N4O4. Mole weight: 252.23.
2'-Deoxyinosine 5'-monophosphate
2'-Deoxyinosine 5'-monophosphate, a vital biomolecule, intricately participates in the synthesis of DNA. With its involvement in the regulation of DNA replication and repair through the nucleotide dITP, this compound paves the way towards improved treatment processes. Notably, this biomolecule is also utilized in the management of autoimmune disorders inclusive of lupus and rheumatoid arthritis. Synonyms: Deoxyinosine monophosphate; 2''-Deoxyinosine-5''-monophosphoric acid; 2'-Deoxy-5'-inosinic acid; 2'-Deoxy-IMP; Hypoxanthine deoxyriboside; 9-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-9H-purin-6-ol. Grades: ≥98% by HPLC. CAS No. 3393-18-8. Molecular formula: C10H13N4O7P. Mole weight: 332.21.
2'-Fluoro-2'-deoxyinosine
2'-Fluoro-2'-deoxyinosine is a biomedical compound used in the reserch of viral infections, specifically for targeting RNA viruses. This compound acting by inhibiting viral replication, thus aiding in the research of these diseases. Synonyms: 9-(2'-Deoxy-2'-fluoro-β-D-ribofuranosyl)-hypoxanthine. Grades: ≥ 99%. Molecular formula: C10H11FN4O4. Mole weight: 270.22.
3'-Amino-2',3'-dideoxyadenosine
3'-Amino-2',3'-dideoxyadenosine is a useful research chemical, a nucleosides that inhibits hepatitis B virus (HBV) replication. Group: Biochemicals. Alternative Names: 9- (3-Amino-2, 3-dideoxy-b-D-erythro-pentafuranosyl) adenine; 9-(3-Amino-2,3-dideoxy-1-D-ribofuranosyI) hypoxanthine; [(2S,3S,5R)-3-amino-5-(6-aminopurin-9-yl)oxolan-2-yl]methanol. Grades: Highly Purified. CAS No. 7403-25-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C??H??N?O?, Molecular Weight: 250.26. US Biological Life Sciences.
Worldwide
3'-Amino-2',3'-dideoxyinosine
3'-Amino-2',3'-dideoxyinosine. Group: Biochemicals. Alternative Names: 9-(3-Amino-2,3-dideoxy-b-D-ribofuranosyl)-hypoxanthine. Grades: Highly Purified. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. US Biological Life Sciences.
Worldwide
3'-Amino-2',3'-dideoxyinosine
3'-Amino-2',3'-dideoxyinosine is a remarkable antiviral compound employed in the research of combatting HIV and hepatitis B afflictions. By impeding the nefarious reverse transcriptase enzyme, this illustrious compound diligently obstructs viral replication, thereby effectuating a substantial reduction in viral load. Synonyms: 9-(3-Amino-2,3-dideoxy-β-D-ribofuranosyl)-hypoxanthine. Grades: ≥ 99%. Molecular formula: C10H13N5O3. Mole weight: 251.24.
3-(Formylamino)-1H-pyrazole-4-carboxamide
An impurity of Allopurinol with inhibitory effects on human hypoxanthine phosphoribosyl transferase. Group: Biochemicals. Alternative Names: 3-Formamidopyrazole-4-carboxamide; Allopurinol Impurity B. Grades: Highly Purified. CAS No. 22407-20-1. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
4-Amino-6-mercaptopyrazolo[3,4-d]pyrimidine
Pyrazolo[3,4-d]pyrimidines have a close structural resemblance to the substrates for the enzyme xanthine oxidase, hypoxanthine (6-hydroxypurine) and xanthine (2. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
6-Amino-5-nitro-2-thiouracil
Hypoxanthine intermediate. Group: Biochemicals. Alternative Names: 6-Amino-2,3-dihydro-5-nitro-2-thioxo-4(1H)-pyrimidinone. Grades: Highly Purified. CAS No. 98020-47-4. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
6-Amino-5-nitro-2-thio-uracil-13C2,15N
Labeled Hypoxanthine intermediate. Group: Biochemicals. Alternative Names: 6-Amino-2,3-dihydro-5-nitro-2-thioxo-4(1H)-pyrimidinone-13C2,15N. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)hypoxanthine, a remarkable antiviral agent and immunosuppressant, exhibits significant potential in combating viral infections such as herpes simplex virus and cytomegalovirus. A potent mechanism arises from its ability to impede viral DNA replication through chain termination, thereby obstructing viral DNA elongation. Synonyms: 2'-FANA-I. Grades: 97%. Molecular formula: C10H11FN4O4. Mole weight: 270.22.
DEANO sodium is notric oxide donor. DEANO sodium potentiates the abilitv of hypoxanthine/xanthine oxidase to induce lipid peroxidation as well as DNA single- and double-strand breaks [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Diethylamine NONOate sodium; Diethylamine nitric oxide sodium. CAS No. 92382-74-6. Pack Sizes: 5 mg. Product ID: HY-160424.
DNA-deoxyinosine glycosylase
DNA-deoxyinosine glycosylase (EC 3.2.2.15) is an enzyme with systematic name DNA-deoxyinosine deoxyribohydrolase. Group: Enzymes. Synonyms: DNA(hypoxanthine) glycohydrolase; deoxyribonucleic acid glycosylase; hypoxanthine-DNA glycosylase. Enzyme Commission Number: EC 3.2.2.15. CAS No. 68247-62-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3969; DNA-deoxyinosine glycosylase; EC 3.2.2.15; 68247-62-1; DNA(hypoxanthine) glycohydrolase; deoxyribonucleic acid glycosylase; hypoxanthine-DNA glycosylase. Cat No: EXWM-3969.
Gedunin
Gedunin is a naturally occurring Hsp90 inhibitor. Induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). It also exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1 μM in parasite development and [3H]-hypoxanthine uptake assays respectively). Grades: >98%. CAS No. 2753-30-2. Molecular formula: C28H34O7. Mole weight: 482.57.
Guanine
Guanine is a purine base which is the component of nucleotides occurring in nucleic acids. Synonyms: 2-Amino-1,9-dihydro-6H-purin-6-one; 2-Amino-6-hydroxy-1H-purine; 2-Amino-6-hydroxypurine; 2-Aminohypoxanthine; 9H-Guanine; 2-Amino-hypoxanthine; Acyclovir Impurity B; Guanin. Grades: ≥98%. CAS No. 73-40-5. Molecular formula: C5H5N5O. Mole weight: 151.13.
Labeled Guanine. Guanine is on one of the five nucleobases incorporated into biological nucleic acids. Guanine, along with adenine and cytosine, is present in both DNA and RNA, whereas thymine is usually seen only in DNA, and uracil only in RNA. Group: Biochemicals. Alternative Names: 2-Amino-1,9-dihydro-6H-purin-6-one-4,8-13C2,7-15N; 2-Amino-6-hydroxy-1H-purine-4,8-13C2,7-15N; 2-Amino-6-hydroxypurine-4,8-13C2,7-15N; 2-Aminohypoxanthine-4,8-13C2,7-15N; 9H-Guanine-4,8-13C2,7-15N; 2-Amino-hypoxanthine-4,8-13C2,7-15N. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Inosine
Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond. Uses: Coenzymes. Synonyms: 1,9-Dihydro-9-β-D-ribofuranosyl-6H-purin-6-one; 9-β-D-Ribofuranosylhypoxanthine; Hypoxanthine 9-β-D-ribofuranoside; Hypoxanthine Ribonucleoside; Hypoxanthine Riboside; Hypoxanthosine; Ribonosine; Atorel; Oxiamin; Trophicardyl; Selfer. Grades: ≥98% by HPLC. CAS No. 58-63-9. Molecular formula: C10H12N4O5. Mole weight: 268.23.
Has neuroprotective properties improving axonal wiring. Has been used to treat stroke patients to restore neural function. Group: Biochemicals. Alternative Names: 1,9-Dihydro-9- β-D-ribofuranosyl-6H-purin-6-one-13C2,15N; 9- β -D-Ribofuranosyl hypoxanthine-13C2, 15N; Hypoxanthine 9- β-D-ribofuranoside-13C2,15N; Hypoxanthine Ribonucleoside-13C2,15N; Hypoxanthine Riboside-13C2,15N. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Inosine-15N4
Inosine is a non-canonical purine nucleoside commonly found in tRNAs. Uses: Biomolecular nmr, genetic therapy, metabolism, metabolomics. Group: 15n labeled compounds. Alternative Names: 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one; Hypoxanthosine; Hypoxanthine D-riboside. CAS No. 204634-01-5. Molecular formula: C10H1215N4O5. Mole weight: 272.2. Appearance: Individual. Canonical SMILES: O[C@H]1[C@] (O[C@@H] ([C@H]1O)CO) ([H])[15N]2C3=C (C ([15N]=C[15NH]3)=O)[15N]=C2. ECNumber: 200-390-4. Catalog: ACM204634015.
Inosine 5'-(tetrahydrogen triphosphate)
Inosine 5'-(tetrahydrogen triphosphate) is a bioactive organic molecule with immense therapeutic potential in addressing an array of ailments- from cancer, metabolic afflictions, to viral infections. It functions as an indispensable precursor for purine nucleotide synthesis, thereby stimulating ATP production, augmenting cellular energy reserves, and activating immune cells such as T-cells to ramp up response to various intruders. Synonyms: ITP; Hypoxanthine; Inosine-5'-Triphosphate. Grades: ≥98% by AX-HPLC. CAS No. 132-06-9. Molecular formula: C10H15N4O14P3. Mole weight: 508.10.
Leteprinim potassium
Leteprinim potassium (AIT-082), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim potassium is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AIT-082. CAS No. 192564-13-9. Pack Sizes: 5 mg. Product ID: HY-120251A.
L-Inosine
L-Inosine is a pivotal nucleoside, showcasing indispensible involvement in energy metabolism and purine nucleotide synthesis. Its profound significance thrives in the biomedical sector, where it acts as a adjunct for studying multifarious ailments such as immune-related disorders, neurodegenerative afflictions and cardiovascular maladies. Synonyms: 9-((2S,3S,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 9-beta-L-Ribofuranosylhypoxanthine; L-ribofuranosyl-Inosine; 1,9-Dihydro-9-β-L-ribofuranosyl-6H-purin-6-one; Hypoxanthine, 9-β-L-ribofuranosyl-; 9-(β-L-Ribofuranosyl)-3,9-dihydro-6H-purin-6-one. Grades: ≥97% by HPLC. CAS No. 21138-24-9. Molecular formula: C10H12N4O5. Mole weight: 268.23.
Purine nucleoside phosphorylase (also known as PNPase) is an enzyme (EC 2.4.2.1) involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine, in each case creating ribose phosphate. NP encodes the enzyme purine nucleoside phosphorylase that together with adenosine deaminase (ADA) serves a key role in purine catabolism, referred to as the salvage pathway. Mutations in either enzyme result in a severe combined immunodeficiency (SCID). Confusingly, the same abbreviation (PNPase), is also used for another, otherwise unrelated, enzyme, namely Polynucleotide Phosphorylase. Purine nucleoside phosphorylase produced in microorganism has a molecular mass of 32 kda. Applications: Useful for enzymatic determination of inorganic phosphate. Group: Enzymes. Synonyms: inos. Enzyme Commission Number: EC 2.4.2.1. CAS No. 9030-21-1. PNPase. Activity: > 500U/mL. Appearance: Colourless to light brown solution. Storage: -20°C. Form: Liquid. Source: Bacillus sp. inosine phosphorylase; PNPase; PUNPI; PUNPII; inosine-guanosine phosphorylase; nucleotide phosphatase; purine deoxynucleoside phosphorylase; purine deoxyribonucleoside phosphorylase; purine nucleoside phosphorylase; purine ribonucleoside phosphorylase; purine-nucleoside: phosphate ribosyltransferase; EC 2.4.2.1. Cat No: DIA-164.
Native Bovine Xanthine Oxidase
Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species. Xanthine oxidase was shown to be involved in the reduction of cytochrome c by the generation of superoxide anions following the oxidation of xanthine. These free radicals are responsible for reducing cytochrome c. Formerly e.c. 1.1.3.22. Group: Enzymes. Synonyms: Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17.3.2; 9002-17-9; XOD; Xanthine:oxygen oxidoreductase; hypoxanthine oxidase; hyp...in. Storage: 2-8°C. Form: Type I, Type II, ammonium sulfate suspension; Suspension in 2.3 M (NH4)2SO4 containing 1 mM sodium salicylate; Type III, ammonium sulfate suspension, Suspension in 2.3 M (NH4)2SO4, 10 mM sodium phosphate buffer, pH 7.8, containing 1 mM EDTA and 1 mM sodium salicylate; Type IV, lyophilized powder, Contains 0.5% sodium salicylate. Source: Bovine milk. Species: Bovine. Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17.3.2; 9002-17-9; XOD; Xanthine:oxygen oxidoreductase; hypoxanthine oxidase; hypoxanthine:oxygen oxidoreductase; Schardinger enzyme; hypoxanthine-xanthine oxidase; xanthine:O2 oxidoreductase; xanthine:xanthine oxidase. Cat No: NATE-0732.
Native Microbial Xanthine Oxidase
Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species. Xanthine oxidase was shown to be involved in the reduction of cytochrome c by the generation of superoxide anions following the oxidation of xanthine. These free radicals are responsible for reducing cytochrome c. Allopurinol is a synthetic drug show to inhibit xanthine oxidase. Applications: This enzyme is useful for enzymatic determination of inorganic phosphorus, 5?-nucleotidase and adenosine deaminase when coupled with purine-nucleoside phosphorylase and uricase. Group: Enzymes. Synonyms: Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17. Enzyme Commission Number: EC 1.17.3.2. CAS No. 9002-17-9. XAO. Mole weight: mol wt ~160 kDa. Activity: > 7 units/mg solid. Storage: -20°C. Form: Lyophilized powder containing BSA and sodium glutamate as stabilizers. Source: Microbial. Xanthine oxidase; XO; xanthine oxidoreductase; EC 1.17.3.2; 9002-17-9; XOD; Xanthine:oxygen oxidoreductase; hypoxanthine oxidase; hypoxanthine:oxygen oxidoreductase; Schardinger enzyme; hypoxanthine-xanthine oxidase; xanthine:O2 oxidoreductase; xanthine:xanthine oxidase. Cat No: NATE-0733.
Native Microorganism Xanthine oxidase
Xanthine oxidase is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid. These enzymes play an important role in the catabolism of purines in some species, including humans. Applications: This enzyme is useful for enzymatic determination of inorganic phosphorus, 5'-nucleotidase and adenosine deaminase when coupled with purine-nucleoside phosphorylase and uricase. Group: Enzymes. Synonyms: EC 1.1.3.22; Xanthine oxidase; XO; XAO. Enzyme Commission Number: EC 1.1.3.22. CAS No. 9054-84-6. XAO. Mole weight: approx. 160 kDa. Activity: Grade? 10U/mg-solid or more. Stability: Stable at-20°C for at least year. Appearance: Reddish brown amorphous powder, lyophilized. Source: Microorganism. EC 1.1.3.22; Xanthine oxidase; XO; XAO. Cat No: DIA-218.
Native Xanthine Dehydrogenase from Bovine milk
Xanthine oxidoreductase (XOR) catalyzes the formation of uric acid from hypoxanthine and xanthine, last two steps of purine catabolism. The mammalian enzyme is synthesized as a xanthine dehydrogenase form (XDH, EC 1.17.1.4), which uses NAD as the electron acceptor, but is converted into an xanthine oxidase form (XO, EC 1.1.3.22) by reversible (through sulfhydryl group oxidation) or irreversible (proteolysis) manner. Since most industrial protocols of XOR purification includes proteolysis step, commercial XOR enzyme is available only as oxidase form unable to use NAD as a an electron acceptor. Group: Enzymes. Synonyms: xanthine dehydrogenase; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase; XDH; EC 1.17.1.4. Enzyme Commission Number: EC 1.17.1.4. CAS No. 9054-84-6. XDH. Form: Lyophilized. Source: Bovine milk. Species: Bovine. xanthine dehydrogenase; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase; XDH; EC 1.17.1.4. Cat No: NATE-1065.
pteridine oxidase
Different from EC 1.17.3.2 xanthine oxidase; does not act on hypoxanthine. Group: Enzymes. Enzyme Commission Number: EC 1.17.3.1. CAS No. 74082-65-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1087; pteridine oxidase; EC 1.17.3.1; 74082-65-8. Cat No: EXWM-1087.
Purine nucleoside phosphorylase, Recombinant
Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine. Mutations in the PNP gene are responsible for purine nucleoside phosphorylase deficiency. Applications: Purine nucleoside phosphorylase is used to study nucleotide salvage pathways and purine metabolism. it is used to study purine nucleoside phosphorylase deficiency and responsible pnp genetic mutations. this product is recombinant and expressed in e. coli. Group: Enzymes. Synonyms: purine-nucleoside phosphorylase; inosine phosphorylase; PNPase; PUNPI; PUNPII; inosine-guanosine phosphorylase; nucleotide phosphatase; purine deoxynucleoside phosphorylase; purine deoxyribonucleoside phosphorylase; purine nucleoside phosphorylase; purine ribonucleoside phosp. Enzyme Commission Number: EC 2.4.2.1. CAS No. 9030-21-1. PNPase. Activity: > 120 U/mL. Storage: -20°C. Form: buffered aqueous solution (100 mM phosphate buffer with 1 mM MgCl2. Source: E. coli. purine-nucleoside phosphorylase; inosine phosphorylase; PNPase; PUNPI; PUNPII; inosine-guanosine phosphorylase; nucleotide phosphatase; purine deoxynucleoside phosphorylase; purine deoxyribonucleoside phosphorylase; purine nucleoside phosphorylase; purine ribonucleoside phosphorylase; EC 2.4.2.1; 9030-21-1. Cat No: NATE-0644.
Recombinant mutant (Met62Val) purine nucleoside phosphorylase from E. coli
Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine. Mutations in the PNP gene are responsible for purine nucleoside phosphorylase deficiency. Applications: These enzymes are widely used for the synthesis of modified nucleotides (virasol, cladribine, fludarabine) which are efficient antiviral and antitumor drugs. Group: Enzymes. Synonyms: purine-nucleoside phosphorylase; inosine phosphorylase; PNPase; PUNPI; PUNPII; inosine-guanosine phosphorylase; nucleotide phosphatase; purine deoxynucleoside phosphorylase; purine deoxyribonucleoside phosphorylase; purine nucleoside phosphorylase;. Enzyme Commission Number: EC 2.4.2.1. CAS No. 9030-21-1. Purity: > 95 %. PNPase. Mole weight: 156 kDa. Activity: 27 U/mg. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: E. coli. purine-nucleoside phosphorylase; inosine phosphorylase; PNPase; PUNPI; PUNPII; inosine-guanosine phosphorylase; nucleotide phosphatase; purine deoxynucleoside phosphorylase; purine deoxyribonucleoside phosphorylase; purine nucleoside phosphorylase; purine ribonucleoside phosphorylase; EC 2.4.2.1; 9030-21-1. Cat No: NATE-1000.
S-methyl-5'-thioinosine phosphorylase
No activity with S-methyl-5'-thioadenosine. The catabolism of of 5'-methylthioadenosine in Pseudomonas aeruginosa involves deamination to S-methyl-5'-thioinosine (EC 3.5.4.31, S-methyl-5'-thioadenosine deaminase) and phosphorolysis to hypoxanthine. Group: Enzymes. Synonyms: MTIP; MTI phosphorylase; methylthioinosine phosphorylase. Enzyme Commission Number: EC 2.4.2.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2673; S-methyl-5'-thioinosine phosphorylase; EC 2.4.2.44; MTIP; MTI phosphorylase; methylthioinosine phosphorylase. Cat No: EXWM-2673.
xanthine dehydrogenase
Acts on a variety of purines and aldehydes, including hypoxanthine. The mammalian enzyme can also convert all-trans retinol to all-trans-retinoate, while the substrate is bound to a retinoid-binding protein. The enzyme from eukaryotes contains [2Fe-2S], FAD and a molybdenum centre. The mammalian enzyme predominantly exists as the NAD-dependent dehydrogenase (EC 1.17.1.4). During purification the enzyme is largely converted to an O2-dependent form, xanthine oxidase (EC 1.17.3.2). The conversion can be triggered by several mechanisms, including the oxidation of cysteine thiols to form disulfide bonds [which can be catalysed by EC 1.8.4.7, enzyme-thiol transhydrogenase (glutathione-disulfide) in the presence of glutathione disulfide] or limited proteolysis, which results in irreversible conversion. The conversion can also occur in vivo. Group: Enzymes. Synonyms: NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase. Enzyme Commission Number: EC 1.17.1.4. CAS No. 9054-84-6. XDH. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1082; xanthine dehydrogenase; EC 1.17.1.4; 9054-84-6; NAD+-xanthine dehydrogenase; xanthine-NAD+ oxidoreductase; xanthine/NAD+ oxidoreductase; xanthine oxidoreductase. Cat No: EXWM-1082.
xanthine oxidase
An iron-molybdenum flavoprotein (FAD) containing [2Fe-2S] centres. Also oxidizes hypoxanthine, some other purines and pterins, and aldehydes, but is distinct from EC 1.2.3.1, aldehyde oxidase. Under some conditions the product is mainly superoxide rather than peroxide: RH + H2O + 2 O2 = ROH + 2 O2.- + 2 H+. The mammalian enzyme predominantly exists as an NAD-dependent dehydrogenase (EC 1.17.1.4, xanthine dehydrogenase). During purification the enzyme is largely converted to the O2-dependent xanthine oxidase form (EC 1.17.3.2). The conversion can be triggered by several mechanisms, including the oxidation of cysteine thiols to form disulfide bonds [which can be catalysed by EC 1.8.4.7, enzyme-thiol transhydrogenase (glutathione-disulfide) in the presence of glutathione disulfide] or limited proteolysis, which results in irreversible conversion. The conversion can also occur in vivo. Group: Enzymes. Synonyms: hypoxanthine o. Enzyme Commission Number: EC 1.17.3.2. CAS No. 9002-17-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1088; xanthine oxidase; EC 1.17.3.2; 9002-17-9; hypoxanthine oxidase; hypoxanthine:oxygen oxidoreductase; Schardinger enzyme; xanthine oxidoreductase; hypoxanthine-xanthine oxidase; xanthine:O2 oxidoreductase; xanthine:xanthine oxidase. Cat No: EXWM-1088.
Xanthine Oxidase from Arthrobacter sp.
Xanthine oxidase is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid. These enzymes play an important role in the catabolism of purines in some species, including humans. Group: Enzymes. Synonyms: EC 1.17.3.2; Xanthine oxidase; XO; XAO. Enzyme Commission Number: EC 1.17.3.2. CAS No. 9002-17-9. Mole weight: 160 kDa (gel). Activity: >50U/mg protein. Storage: Store at -20°C. Form: Reddish brown amorphous powder, lyophilized. Source: Arthrobacter sp. EC 1.17.3.2; Xanthine oxidase; XO; XAO; XOD. Cat No: NATE-1719.
XTP/dITP diphosphatase
The enzymes from the bacterium Escherichia coli and the archaea Methanococcus jannaschii and Archaeoglobus fulgidus are highly specific for XTP and dITP. The activity is dependent on divalent cations, Mg2+ is preferred. Group: Enzymes. Synonyms: hypoxanthine/xanthine dNTP pyrophosphatase; rdgB (gene name). Enzyme Commission Number: EC 3.6.1.66. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4639; XTP/dITP diphosphatase; EC 3.6.1.66; hypoxanthine/xanthine dNTP pyrophosphatase; rdgB (gene name). Cat No: EXWM-4639.
7N-[1- (2-Carboxy) ethyl]allopurinol
7N-[1- (2-Carboxy) ethyl]allopurinol. Group: Biochemicals. Alternative Names: 1,6-Dihydro-6-oxo-9H-purine-9-propanoic Acid; 9H-Hypoxanthin-9-ylpropionic Acid; NSC 79667. Grades: Highly Purified. CAS No. 34397-00-7. Pack Sizes: 250mg. US Biological Life Sciences.
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