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Ibudilast. Group: Biochemicals. Grades: Purified. CAS No. 50847-11-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ibudilast
Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barrier, is well tolerated, is active on oral administration, reduces glial activation and attenuates pain symptoms in diverse rat models of neuropathic pain. In addition, it enhances acute morphine analgesia and attenuates morphine tolerance and withdrawal. Thus ibudilast may improve opioid efficacy and is a promising therapeutic candidate for neuropathic pain. Synonyms: MN-166, MN166, MN 166, AV-411, AV 411, AV411, KC404; KC-404; KC 404; Ibudilast. Grade: >98%. CAS No. 50847-11-5. Molecular formula: C14H18N2O. Mole weight: 230.31.
Ibudilast
Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase ( PDE ) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KC-404; AV-411; MN-166. CAS No. 50847-11-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0763.
Ibudilast
Ibudilast. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IBUDILAST;IBUDILAST-D7;KC-404;1-PROPANONE, 2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL];2-isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine;2-METHYL-1-[2-(1-METHYLETHYL)PYRAZOLO[1,5-A]PYRIDIN-3-YL]-1-PROPANONE;3-ISOBUTYRYL-2-ISOPROPYLPYRAZOLO(1,5-A)PYRIDINE;2-methyl-1-(2-(1-methylethyl)pyrazolo(1,5-a)pyridin-3-yl)-1-propanon. Appearance: solid. CAS No. 50847-11-5. Molecular formula: C14H18N2O. Mole weight: 230.31. Purity: 99+%. IUPACName: 2-methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one. Canonical SMILES: CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C. Density: 1.09. Product ID: ACM50847115. Alfa Chemistry ISO 9001:2015 Certified.
Ibudilast-d3 (Major)
Labeled Ibudilast. A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral). Group: Biochemicals. Alternative Names: 2-Methyl-1-[2- (1-methylethyl) pyrazolo[1, 5-a]pyridin-3-yl]-1-propanone-d3; 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one-d3; 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine-d3; 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine-d3; AV 411-d3; KC 404-d3; Ketas-d3. Grades: Highly Purified. CAS No. 102064-45-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ibudilast-[d7]
Ibudilast-[d7] is a labelled analogue of Ibudilast. Ibudilast is a phosphodiesterase inhibitor with anti-inflammatory, vasodilator and neuroprotective properties. It can be used in the treatment of asthma, stroke and multiple sclerosis. Synonyms: Ibudilast D7. Grade: 95% by HPLC; 95% atom D. CAS No. 1204192-90-4. Molecular formula: C14H11D7N2O. Mole weight: 237.35.
Ibudilast impurity 2
Ibudilast impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 101162-42-9. Molecular formula: C14H20N2O3. Mole weight: 264.33. Catalog: APB101162429.
Ibudilast impurity 4
Ibudilast impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 102064-45-9. Molecular formula: C14H14D4N2O. Mole weight: 234.34. Catalog: APB102064459.
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