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| Product | Description | |
|---|---|---|
| Idelalisib | Idelalisib (CAL-101; GS-1101) is a highly selective and orally bioavailable p110δ inhibitor with an IC 50 of 2.5 nM, showing 40- to 300-fold selectivity for p110δ over other PI3K class I enzymes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CAL-101; GS-1101. CAS No. 870281-82-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13026. |  |
| Idelalisib | Idelalisib is a kinase inhibitor. In combination with rituximab, it was used for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Synonyms: Idelalisib; CAL101; CAL 101; CAL-101; GS1101; GS 1101; GS-1101, Idelalisib. Grade: > 95%. CAS No. 870281-82-6. Molecular formula: C22H18FN7O. Mole weight: 415.432. |  |
| Idelalisib | It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is a member of purines, an organofluorine compound, a member of quinazolines, an aromatic amine and a secondary amino compound. Alternative Names: Idelalisib CAL-101 Zydelig GS-1101. CAS No. 870281-82-6. Product ID: API870281826. Molecular formula: C22H18FN7O. Mole weight: 415.4. EINECS: 807-438-9. SMILES: CCC(C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5. Appearance: White to off-white powder. Standard: Facility GMP. Category: Anti-Tumor APIs. |  |
| Idelalisib-[d5] | Idelalisib-[d5] is the labelled analogue of Idelalisib. Idelalisib is a chemotherapy drug used for the treatment of relapsed chronic lymphocytic leukemia (CLL), follicular B-cell non-Hodgkin lymphoma and small lymphocytic lymphoma (SLL). Synonyms: Idelalisib D5. Grade: 95% by HPLC; 95% atom D. CAS No. 1830330-31-8. Molecular formula: C22H13D5FN7O. Mole weight: 420.45. | |
| Idelalisib Metabolit | Idelalisib Metabolite is a metabolite of Idelalisib, a drug primarily employed in the treatment of chronic lymphocytic leukemia and follicular lymphoma. Synonyms: GS-563117. Grade: > 95%. Molecular formula: C22H18FN7O2. Mole weight: 431.43. | |
| Idelalisib Metabolit-d5 | Idelalisib Metabolit-d5. Grade: > 95%. Molecular formula: C22H13FN7O2D5. Mole weight: 436.46. | |
| Idelalisib N-Glucuronide | Idelalisib N-Glucuronide is an exclusive metabolite of Idelalisib, a prominent therapeutic agent for chronic lymphocytic leukemia (CLL), follicular lymphoma, and small lymphocytic lymphoma, exhibiting its efficacious function as a precise and strategic kinase inhibitor. Grade: > 95%. Molecular formula: C28H27FN7O7. Mole weight: 592.57. | |
| 2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone | 2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino) benzamide to a nonracemic quinazoline as the key step. Group: Biochemicals. Grades: Highly Purified. CAS No. 870281-86-0. Pack Sizes: 100mg, 500mg. Molecular Formula: C17H16FN3O. US Biological Life Sciences. |  Worldwide |
| 2-Amino-6-fluoro-N-phenylbenzamide | 2-Amino-6-fluoro-N-phenylbenzamide is used as reactant/reagent in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino) benzamide to a nonracemic quinazoline as the key step. 2-Amino-6-fluoro-N-phenyl-benzamide is obtained from 2-fluoro-6-nitro-benzoic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 1417456-04-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C13H11FN2O, Molecular Weight: 230.24. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-6-nitro-N-phenylbenzamide | 2-Fluoro-6-nitro-N-phenylbenzamide is an intermediate used in the synthesis of an antitumor agent Idelalisib I. Group: Biochemicals. Grades: Highly Purified. CAS No. 870281-83-7. Pack Sizes: 250mg, 1g. Molecular Formula: C13H9FN2O3, Molecular Weight: 260.22. US Biological Life Sciences. | Worldwide |
| 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]-4(3H)-quinazolinone | 5-Fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]-4(3H)-quinazolinone is an impurity of Idelalisib, which is a kinase inhibitor used in combination with rituximab for the treatment of relapsed or refractory chronic lymphocytic leukemia (CLL). Synonyms: 4(3H)-Quinazolinone, 5-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]-; 4(3H)-Quinazolinone, 5-fluoro-3-phenyl-2-[(1S)-1-(1H-purin-6-ylamino)ethyl]-; (S)-2-(1-(9H-Purin-6-ylamino)ethyl)-5-fluoro-3-phenylquinazolin-4(3H)-one. Grade: 95%. CAS No. 870281-17-7. Molecular formula: C21H16FN7O. Mole weight: 401.40. | |
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