Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| 3-O-Benzyl-1-thiophenyl-L-iduronic acid |  | |
| 4-? Methyl-? 2-? oxo-? 2H-? 1-? benzopyran-? 7-? yl-β -? D-? glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate | As a protected metabolite of 4-Methylumbelliferyl α-L-Idopyranosiduronic Acid, 4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester is a fluorogenic substrate in the assay of a-L-Iduronidase and is useful in the detection of Hurlers syndrome. Synonyms: 4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester. Grades: 95%. CAS No. 101014-65-7. Molecular formula: C23H24O12. Mole weight: 492.43. | |
| 4-Methylumbelliferyl a-L-idopyranosiduronic acid 2-sulphate disodium salt | 4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-IdoA 2-sulfate) is a fluorogenic substrate for α-L-iduronidase that has been used in an assay to detect Hurler syndrome. It is also a substrate for iduronate-2-sulfatase that can be used for diagnosis of Hunter disease (MPS II). Synonyms: 4-Methylumbelliferyl-α-L-Idopyranosiduronic Acid 2-sulfate disodium salt; 4-MU-α-IdoA 2-sulfate disodium salt; (2R,3S,4S,5R,6S)-3,4-dihydroxy-6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)-5-(sulfonatooxy)tetrahydro-2H-pyran-2-carboxylate disodium salt. Grades: ≥98%. CAS No. 1045020-74-3. Molecular formula: C16H14Na2O12S. Mole weight: 476.3. | |
| 4-Methylumbelliferyl a-L-idopyranosiduronic acid cyclohexylammonium salt | 4-Methylumbelliferyl a-L-idopyranosiduronic acid cyclohexylammonium salt is a key compound used in the biomedical industry for studying lysosomal storage diseases. It serves as a substrate to measure the activity of iduronate-2-sulfatase, an enzyme involved in the degradation of glycosaminoglycans. This product enables precise and sensitive detection of enzyme deficiencies related to Hurler, Hunter, and Sanfilippo syndromes, facilitating disease diagnosis and treatment monitoring. Synonyms: 4-Methylumbelliferyl a-L-iduronic acid cyclohexylammonium salt 4-MU-a-L-ldoA CHX. CAS No. 66895-33-8. Molecular formula: C16H16O9.C6H13N. Mole weight: 451.47. | |
| 4-Methylumbelliferyl a-L-idopyranosiduronic acid sodium salt | It is a fluorogenic substrate in the assay of a-L-Iduronidase. Synonyms: Sodium (4-methylumbelliferyl a-L-idopyranosid)uronate; 4-Methylumbelliferyl α-L-Iduronic Acid, Sodium Salt; Sodium 4-methyl-2-oxo-2H-chromen-7-yl α-L-idopyranosiduronate; 2H-1-Benzopyran-2-one, 7-(α-L-idopyranuronosyloxy)-4-methyl-, sodium salt (1:1). Grades: ≥95%. CAS No. 89157-94-8. Molecular formula: C16H15NaO9. Mole weight: 374.27. | |
| 5-Deoxy-5-fluoro-1,2-O-isopropylidene-D-iduronic acid-3,6 lactone | | |
| L-Iduronic acid | L-Iduronic acid, a highly significant compound prevalent in the biomedical field, finds extensive application. In the pursuit of combating diverse ailments like cancer, cardiovascular diseases, and inflammatory disorders, this compound serves as an indispensable component for drug synthesis. Its remarkable attributes render it crucial for formulating drug delivery systems that augment therapeutic efficacy. Synonyms: Iduronic acid, L-; Aldehydo-L-iduronic acid. Grades: ≥95%. CAS No. 2073-35-0. Molecular formula: C6H10O7. Mole weight: 194.14. | |
| L-Iduronic acid-1,6-13C2 | L-Iduronic acid-1,6-13C2 is a valuable biochemical utilized in the biomedical industry for its role in synthesizing drugs used to study diseases related to abnormal glycosaminoglycan metabolism. Its isotopic label, 13C2, aids in research and drug development, facilitating accurate tracing and analysis of metabolic pathways. Molecular formula: 13C2C4H10O7. Mole weight: 2523.81. | |
| L-Iduronic acid sodium salt | L-Iduronic acid sodium salt, a highly significant compound prevalent in the biomedical field, finds extensive application. In the pursuit of combating diverse ailments like cancer, cardiovascular diseases, and inflammatory disorders, this compound serves as an indispensable component for drug synthesis. Its remarkable attributes render it crucial for formulating drug delivery systems that augment therapeutic efficacy. Uses: A constituent of certain mucopolysaccharides. Synonyms: Sodium L-iduronate; L-Iduronic acid, monosodium salt; (2R,3S,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexanoate sodium salt. Grades: ≥95%. CAS No. 61199-83-5. Molecular formula: C6H9NaO7. Mole weight: 216.12. | |
| 4-Methylumbelliferyl 1,2-O-(Dibutylsulfane)-α-L-Idopyranuronic Acid Methyl Ester | As an intermediate used in the synthesis of 4-Methylumbelliferyl α-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt, 4-Methylumbelliferyl 1,2-O-(dibutylsulfane)-α-L-Idopyranuronic Acid Methyl Ester is a fluorogenic substrate in the assay of α-L-Iduronidase. A fluorimetric enzyme assay for the diagnosis of MPS II (Hunter disease). Molecular formula: C25H34O9S. Mole weight: 510.6. | |
| 4-Methylumbelliferyl a-L-iduronide | It is a fluorogenic substrate for α-L-iduronidase. Synonyms: 4-methyl-2-oxo-2H-1-benzopyran-7-yl α-L-idopyranosiduronic acid; 4-Methylumbelliferyl-α-L-Idopyranosiduronic Acid; 4-MU-α-IdoA; MU-α-IdoA?. Grades: ≥90%. CAS No. 66966-09-4. Molecular formula: C16H16O9. Mole weight: 352.29. | |
| α-L-Iduronidase from Human, Recombinant | This enzyme catalyses the hydrolysis of unsulfated α-L-iduronosidic linkages in dermatan sulfate. In lysosomal degradation process α-L-Iduronidase plays a crucial role. It hydrolyzes the non-reducing terminal α-L-iduronic acid residues in GAGs, including dermatan sulfate and heparan sulfate. It is involved in the degeneration of glycosaminoglycans such as dermatan sulfate and heparan sulfate. It is found in the lysosomes of cells. Applications: Α-l-iduronidase may be used for leukocyte assay in the study of a-l-iduronidase deficiency in new born. Group: Enzymes. Synonyms: Iduronidase; EC 3.2.1.76; L-iduronidase; alpha-L-iduronidase); glycosaminoglycan alpha-L-iduronohydrolase; IDUA; α-L-Iduronidase. Enzyme Commission Number: EC 3.2.1.76. IDUA. Mole weight: 71 kDa. Activity: >7,500 units/μg protein. Storage: Store at -20°C. Form: Supplied as a solution in 40 mM sodium acetate , 400 mM NaCl and 20% (v/v) glycerol, pH 5.0. Source: Mouse NSO cells. Species: Human. Iduronidase; EC 3.2.1.76; L-iduronidase; alpha-L-iduronidase); glycosaminoglycan alpha-L-iduronohydrolase; IDUA; α-L-Iduronidase. Cat No: NATE-0930. |  |
| Chondroitin ABC lyase from Bacteroides thetaiotaomicron, Recombinant | Chondroitinase ABC is an enzyme from Bacteroides thetaiotaomicron that cleaves the endo-1,4-β-galactosaminic bonds between acetylgalactosamine and either glucuronic or iduronic acid. Group: Enzymes. Synonyms: chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; EC 4.2.2.20. Enzyme Commission Number: EC 4.2.2.20. Purity: >90% as judged by SDS-PAGE. Chondroitinase ABC. Mole weight: 47.6 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacteroides thetaiotaomicron. chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; EC 4.2.2.20. Cat No: NATE-1548. | |
| chondroitin AC lyase | Acts on chondroitin 4-sulfate and chondroitin 6-sulfate, but less well on hyaluronate. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of GlcA. GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming the repeating disaccharide [-4)IdoA(α1-3)GalNAc(β1-]n of DS. Both the concentrations and locations of sulfate-ester substituents vary with glucosaminoglycan source. Group: Enzymes. Synonyms: chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC. Enzyme Commission Number: EC 4.2.2.5. CAS No. 9047-57-8. ChnAC. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5104; chondroitin AC lyase; EC 4.2.2.5; 9047-57-8; chondroitinase (ambiguous); chondroitin sulfate lyase; chondroitin AC eliminase; chondroitinase AC; ChnAC. Cat No: EXWM-5104. | |
| Chondroitinase B from Flavobacterium heparinum, Recombinant | In enzymology, a chondroitin B lyase (EC 4.2.2.19) is an enzyme that catalyzes the chemical reaction:Eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (deltaUA-GalNAc-4S). This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The enzyme cleaves, via an elimination mechanism, polysaccharide chains containing 1-4 linkages between hexosamines and iduronic acid residues in dermatan sulfate (chondroit...preparation of di-and oligo-saccharides of dermatan sulfate. Group: Enzymes. Synonyms: Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. Purity: > 90 % by reversed phase HPLC analysis. ChonB. Mole weight: 54,779 Da. Activity: > 550 IU/mg (substrate: dermatan sulfate). Stability: Expiration is 30 months from manufacturing date, frozen at -70°C in aqueous buffers containing Sodium Chloride, Sodium Phosphate and Sucrose 5%. Source: Flavobacterium heparinum. Species: Flavobacterium heparinum. Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Pack: vial of 5 ug. Cat No: NATE-0130. | |
| chondroitin B lyase | This is the only lyase that is known to be specific for dermatan sulfate as substrate. The minimum substrate length required for catalysis is a tetrasaccharide. In general, chondroitin sulfate (CS) and dermatan sulfate (DS) chains comprise a linkage region, a chain cap and a repeat region. The repeat region of CS is a repeating disaccharide of glucuronic acid (GlcA) and N-acetylgalactosamine (GalNAc) [-4)GlcA(β1-3)GalNAc(β1-]n, which may be O-sulfated on the C-4 and/or C-6 of GalNAc and C-2 of GlcA. GlcA residues of CS may be epimerized to iduronic acid (IdoA) forming the repeating disaccharide [-4)IdoA(α1-3)GalNAc(β1-]n of DS. Both the concentrations and locations of sulfate-ester substituents vary with glucosaminoglycansource. Group: Enzymes. Synonyms: chondroitinase B; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. ChonB. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5094; chondroitin B lyase; EC 4.2.2.19; 52227-83-5; chondroitinase B; ChonB; ChnB. Cat No: EXWM-5094. | |
| Heparinase I | This enzyme selectively cleaves highly sulfated polysaccharide chains containing 1-4 linkages between N-sulfated glucaoamine and 2-O-sulfated iduronic acid. It cleaves heparin sulfate but only to a limited extent in the sulfated zone. It also cleaves the antithrombin III pentasaccharide unit in the heparin molecule. Optimum pH 7.0-7.6. Stabilised with 0.2-0.4% BSA, 0.22 μm sterile filtered and dispensed into sterile tubes/vials. Synonyms: Native Flavobacterium Heparinum Heparinase I; EC 4.2.2.7; Heparinase I; Heparin Eliminase; Heparinase; Heparin Lyase; Heparinase I From Bacteroides Eggerthii, Recombinant. Grades: 95%. CAS No. 9025-39-2. Mole weight: 42.8 kDa. | |
| Heparinase I from Bacteroides eggerthii, Recombinant | Heparin-degrading lyase that recognizes heparin sulfate proteoglycan as its primary substrate. Heparinase I and III plays vital role in various biological processes: modulate cell-growth factor interactions, cell-lipoprotein interactions, neovascularization. It cleaves highly sulphated polysaccharide chains in presence of 2-O-sulfated α-L-idopyranosyluronic acid and β-D-glucopyranosyluronic acid residues of polysaccharides. Bacteroides heparinase i cloned from bacteroides eggerthii, also called heparin lyase i, is active on heparin and the highly sulfated domains of heparan sulfate. the reaction yields oligosaccharide products containing unsaturated uroni...heparinase i has a much higher rate of cleavage for 2-o sulfated iduronic acid residues. limited digest of porcine mucosal heparin with flavobacterium heparinum heparinase i results in sulfated heparin oligosaccharides structures previously reported. limited digest of porcine mucosal heparin with the bacteroides heparinase i results in heparin oligosaccharides with a lower extent of sulfation as reported. Group: Enzymes. Synonyms: Heparinase; Heparin lyase; Heparin eliminase; Heparin-sulfate lyase; Heparin-sulfate eliminase; Heparitin-sulfate lyase; Heparinase I; Heparinase III; Heparin lyase II; Heparinase II. CAS No. 9025-39-2. Purity: > 95% determined by SDS-PAGE | |
| Heparinase II from Flavobacterium heparinum | This enzyme cleaves most links in heparin and heparin sulfate. It is relatively non-specific for 1-4 links in sulfated polysaccharide chains between hexosamines and glucuronic acid plus iduronic acids, but does not fully depolymerise either. Optimum pH 7.0-7.6. Stabilised with 0.2-0.4% BSA, 0.22 μm sterile filtered and dispensed into sterile tubes/vials. Synonyms: Heparinase II; Heparin lyase II; EC 4.2.2.8. CAS No. 149371-12-0. Mole weight: 84.1 kDa. | |
| Heparinase III | The enzyme cleaves 1-4 linkages between N-acetylated or N-sulphated glucosamine and glucuronic acid residues. It is only active towards heparan sulfate in the low sulphated zone and does not cleave heparin or low molecular weight heparins. Highly sulfated zones are resistant to it and activity towards iduronic acid is very low. Stabilised with 0.2-0.4% BSA, 0.22 μm sterile filtered and dispensed into sterile tubes/vials. Synonyms: Heparinase III from Flavobacterium heparinum; Heparin Lyase III; Heparitinase I; Heparan monosulfate lyase; Heparin sulfate eliminase; Heparin-sulfate lyase. CAS No. 37290-86-1. Mole weight: 70.8 kDa. | |
| Native Flavobacterium heparinum Chondroitinase B | Chondroitinase B cleaves, via an elimination mechanism, polysaccharide chains containing 1-4 linkages between hexosamines and iduronic acid residues in dermatan sulfate (chondroitin B).The reaction yields oligosaccharide products (mainly disaccharides) containing unsaturated uronic acids which can be detected by UV spectroscopy at 232 nm. Applications: Research reagent (glycobiology, preparation of oligosaccharide libraries from dermatan sulfate).determination of contents of chondrotin sulfates by hplc. Group: Enzymes. Synonyms: Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Enzyme Commission Number: EC 4.2.2.19. CAS No. 52227-83-5. ChonB. Mole weight: 55 kDa. Activity: >200 IU/mg (substrate: dermatan sulfate). Stability: 12 months frozen at -20°C in aqueous buffers containing sodium phosphate and sucrose 5%. Source: Flavobacterium heparinum. Chondroitinase B; EC 4.2.2.19; chondroitin B lyase; ChonB; ChnB. Cat No: NATE-1950. | |
| unsaturated chondroitin disaccharide hydrolase | The enzyme releases 4-deoxy-4,5-didehydro D-glucuronic acid or 4-deoxy-4,5-didehydro L-iduronic acid from chondroitin disaccharides, hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1?3) and (1?4) bonds. It prefers the sulfated disaccharides to the unsulfated disaccharides. Group: Enzymes. Synonyms: UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Enzyme Commission Number: EC 3.2.1.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3864; unsaturated chondroitin disaccharide hydrolase; EC 3.2.1.180; UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Cat No: EXWM-3864. | |
| 1,2-O-Isopropylidene- β-L-idofuranuronic Acid 5-(4-Nitrobenzoate) | 1,2-O-Isopropylidene- β-L-idofuranuronic Acid 5-(4-Nitrobenzoate) is an intermediate in the synthesis of fluorogenic substrate in the assay of a-L-Iduronidase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 1g. Molecular Formula: C16H15NO9. US Biological Life Sciences. |  Worldwide |
| L-iduronidase | Iduronidase (EC 3.2.1.76, L-iduronidase, alpha-L-iduronidase, laronidase) is an enzyme with the systematic name glycosaminoglycan alpha-L-iduronohydrolase. This enzyme catalyses the hydrolysis of unsulfated alpha-L-iduronosidic linkages in dermatan sulfate.It is a glycoprotein enzyme found in the lysosomes of cells. It is involved in the degeneration of glycosaminoglycans such as dermatan sulfate and heparan sulfate. The enzyme acts by hydrolyzing the terminal alpha-L-induronic acid residues of these molecules, degrading them. The protein is reported as having a mass of approximately 83 kilodaltons. Group: Enzymes. Synonyms: α-L-iduronidase. Enzyme Commission Number: EC 3.2.1.76. CAS No. 9073-56-7. IDUA. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3940; L-iduronidase; EC 3.2.1.76; 9073-56-7; α-L-iduronidase. Cat No: EXWM-3940. | |
| Methyl 1,2,3,4-Tetra-O-Acetyl-Α-L-Idopyranuronate | Heterocyclic Organic Compound. Alternative Names: Methyl 1,2,3,4-Tetra-O-acetyl-|A-L-iduronate, |A-L-Idopyranuronic Acid Methyl Ester Tetraacetate, Methyl 1,2,3,4-Tetra-O-acetyl-|A-L-idopyranuronate, 108032-41-3. CAS No. 108032-41-3. Molecular formula: C15H20O11. Mole weight: 376.32. Purity: 0.96. IUPACName: methyl (2R,3S,4S,5R,6S)-3,4,5,6-tetraacetyloxyoxane-2-carboxylate. Canonical SMILES: CC (=O)OC1C (C (OC (C1OC (=O)C)OC (=O)C)C (=O)OC)OC (=O)C. Catalog: ACM108032413. |  |
| Native Proteus vulgaris Chondroitinase ABC | Chondroitinase ABC catalyzes the eliminative degradation of polysaccharides containing (1-4)-β-D-hexosaminyl and (1-3)-β-D-glucuronosyl or (1-3)-α-L-iduronosyl linkages to disaccharides containing 4-deoxy-β-D-gluc-4-enuronosyl groups. It acts on chondroitin 4-sulfate, chondroitin 6-sulfate, and dermatan sulfate, and acts slowly on hyaluronate. The molecular weight is found to be approximately 120 kDa with 2 non-identical subunits of molecular masses 86 kDa and 32 kDa. The pH optimum is found to be 8.0 with chondroitin sulfate and 6.8 with hyaluronic acid and tempeRature optimum is 37°C. 1 mM Zn2+ acts as an inhibitor, while 0.05 M acetate is an activ...BC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; 9024-13-9. Enzyme Commission Number: EC 4.2.2.4. CAS No. 9024-13-9. Chondroitinase ABC. Activity: 50-250 units/mg protein (using chondroitin sulfate C as substrate); 0.3-3 units/mg solid (using chondroitin sulfate C as substrate). Storage: -20°C. Form: lyophilized powder. Source: Proteus vulgaris. EC 4.2.2.4, chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; 9024-13-9. Cat No: NATE-0131. | |
Our database is helping our users find suppliers everyday.
