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IM-12 is an inhibitor of GSK-3?, with an IC50 of 53 nM, and also enhances Wnt signalling. Uses: Scientific research. Group: Signaling pathways. CAS No. 1129669-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12292.
GSK3? Inhibitor XIX, IM-12
The GSK3? Inhibitor XIX, IM-12 controls the biological activity of GSK3?. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
An impurity of Brexpiprazole, a dopamine D2 partial agonist used as an atypical antipsychotic drug. Brexpiprazole has been approved for the treatment of schizophrenia. Synonyms: Brexpiprazole Impurity-12. CAS No. 2116542-19-7. Molecular formula: C22H20N2O4. Mole weight: 376.41.
8-(N-Acetylamino-L-arginine)-goserelin
8-(N-Acetylamino-L-arginine)-goserelin is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-D-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro(Ac)-NHNHCONH2; (S)-N-((9S,12S,15R,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-15-(tert-butoxymethyl)-9-((S)-2-(2-carbamoylhydrazinecarbonyl)pyrrolidine-1-carbonyl)-18-(4-hydroxybenzyl)-21-(hydroxymethyl)-28-(1H-imidazol-5-yl)-4-imino-12-isobutyl-2,11,14,17,20,23,26-heptaoxo-3,5,10,13,16,19,22,25-octaazaoctacosan-27-yl)-5-oxopyrrolidine-2-carboxamide. Molecular formula: C61H86N18O15. Mole weight: 1311.47.
Glucagon arbitrary peak IV
Glucagon arbitrary peak IV is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Synonyms: H-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Glu-Trp-Leu-Met-Asn-Thr-OH; (2S,5S,8S,11S,14S,17S,20S,23S,26S)-14-((1H-indol-3-yl)methyl)-5-(2-amino-2-oxoethyl)-26-((6S,9S,12S,15S)-1-amino-6-((S)-2-amino-3-hydroxypropanamido)-15-(3-amino-3-oxopropyl)-9-(3-guanidinopropyl)-1-imino-12-methyl-7,10,13-trioxo-2,8,11,14-tetraazahexadecanamido)-23-benzyl-17-(2-carboxyethyl)-2-((R)-1-hydroxyethyl)-11-isobutyl-20-isopropyl-8-(2-(methylthio)ethyl)-4,7,10,13,16,19,22,25-octaoxo-3,6,9,12,15,18,21,24-octaazaoctacosane-1,28-dioic acid. Molecular formula: C76H117N23O23S. Mole weight: 1752.95.
H-Arg-Thr-Leu-Glu-Gly-Ser-OH
H-Arg-Thr-Leu-Glu-Gly-Ser-OH is a protected hexapeptide used in peptide synthesis. It comprises arginine (Arg), threonine (Thr), leucine (Leu), glutamic acid (Glu), glycine (Gly), and serine (Ser), with a free -OH group at the C-terminus for further modifications or coupling. This peptide is designed for controlled reactivity and stability, and can be utilized in various applications including peptide-based drug design, molecular recognition studies, and functional peptide research. Synonyms: Arg-Thr-Leu-Glu-Gly-Ser; (6S,9S,12S,15S,21S)-1,6-Diamino-15-(2-carboxyethyl)-9-((R)-1-hydroxyethyl)-21-(hydroxymethyl)-1-imino-12-isobutyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosan-22-oic acid. Grade: ≥95%. Molecular formula: C26H47N9O11. Mole weight: 661.71.
The pentapeptide TRSAW is a potent inhibitor of osteoclastic bone resorption in vitro. Synonyms: (6S,9S,12S,15S)-15-((1H-indol-3-yl)methyl)-1-amino-6-((2S,3R)-2-amino-3-hydroxybutanamido)-9-(hydroxymethyl)-1-imino-12-methyl-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid; pTH-rP (107-111) (human, bovine, dog, horse, mouse, rabbit, rat). CAS No. 138949-73-2. Molecular formula: C27H41N9O8. Mole weight: 619.67.
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