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| Product | Description | |
|---|---|---|
| Imiquimod | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C14H16N4. CAS No. 99011-02-6. Prepack ID 40279313-1g. Molecular Weight 240.31. See USA prepack pricing. |  |
| Imiquimod | An agonist of TLR7 with immune response modifying activity, Approved for basal cell carcinoma, In Phase III for VIN and CIN, Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. Uses: An immune response modifier. it stimulates the production of interferon-a. Synonyms: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837; S-26308; Aldara; TMX-101; 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-; 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine; 1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-ylamine; Aldara; Beselna; Keravort; R 837; R837; S 26308; TMX 101; Zartra; Zyclara. Grades: >98%. CAS No. 99011-02-6. Molecular formula: C14H16N4. Mole weight: 240.30. |  |
| Imiquimod | Cell-permeable. Topical immune response modifier that displays anti-angiogenic, anti-viral and anti-inflammatory properties. Up-regulates IL-18 and down-regulates MMP-9 through recognition of Toll-like receptor 7 (TLR7) and subsequent activation of MyD88-dependent pathway. Stimulates proinflammatory cytokine production interferon-alpha (IFN-alpha), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) and activates NF-kappaB. Caspase-3 activator that directly induces procaspase-3 cleavage. Anti-cancer compound. Apoptosis inducer. Antiproliferative, independent of immune system activation or function. Approved treatment for external genital warts caused by human papillomavirus infection. Group: Biochemicals. Alternative Names: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837; S-26308. Grades: Highly Purified. CAS No. 99011-02-6. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C14H16N4. US Biological Life Sciences. |  Worldwide |
| Imiquimod | Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 837. CAS No. 99011-02-6. Pack Sizes: 100 mg; 200 mg; 500 mg. Product ID: HY-B0180. |  |
| Imiquimod hydrochloride | Imiquimod hydrochloride is an immune response modifier. It acts as a toll-like receptor 7 agonist. It is commonly used topically to treat warts on the skin of the genital and anal areas. It is also used to treat certain diseases of the skin, including skin cancers, such as basal cell carcinoma, Bowen's disease, superficial squamous cell carcinoma, some superficial malignant melanomas, and actinic keratosis. It can lead to the activation of Langerhans cells, which subsequently migrate to local lymph nodes to activate the adaptive immune system when applied to skin. Synonyms: R 837 hydrochloride; R837 hydrochloride; R-837 hydrochloride; 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-, hydrochloride (1:1); 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(2-methylpropyl)-, monohydrochloride; Imiquimod monohydrochloride. Grades: ≥95%. CAS No. 99011-78-6. Molecular formula: C14H17ClN4. Mole weight: 276.76. | |
| Imiquimod hydrochloride | Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 837 hydrochloride. CAS No. 99011-78-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0180A. | |
| Imiquimod Impurity 1 (S-26704) | used in the design of immunomodulating agents for use as vaccine adjuvants and anticancer treatments. Synonyms: 2-Hydroxy Imiquimod; 4-Amino-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; R 842; R 842 (pharmaceutical); 1-(4-Amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol; 2-Hydroxy Imiquimod. Grades: > 95%. CAS No. 112668-45-8. Molecular formula: C14H16N4O. Mole weight: 256.31. | |
| Imiquimod Impurity 2 | Imiquimod Impurity 2 is an immune response modifier. It stimulates the production of interferon-a. Synonyms: 3-Hydroxy Imiquimod; 4-Amino-β-methyl-1H-imidazo[4,5-c]quinoline-1-propanol. Grades: > 95%. CAS No. 1807606-78-5. Molecular formula: C14H16N4O. Mole weight: 256.30. | |
| Imiquimod Impurity 3 | Synonyms: N-(4-Isobutylamino-quinolin-3-yl)-formamide. Grades: > 95%. Molecular formula: C14H17N3O. Mole weight: 243.31. | |
| Imiquimod Impurity 4 | Imiquimod Impurity 4 is one of Imiquimod impurities, Imiquimod is an immune response modifier. It stimulates the production of interferon-a. Molecular formula: C15H16N4O. Mole weight: 268.31. | |
| Imiquimod Impurity 5 | Imiquimod Impurity 5 is one of Imiquimod impurities, Imiquimod is an immune response modifier. It stimulates the production of interferon-a. CAS No. 853793-02-9. Molecular formula: C15H18N4. Mole weight: 254.33. | |
| Imiquimod Impurity 6 | Imiquimod Impurity 6 is one of Imiquimod impurities, Imiquimod is an immune response modifier. It stimulates the production of interferon-a. CAS No. 99010-99-8. Molecular formula: C14H15N3O. Mole weight: 241.29. | |
| Imiquimod maleate | Imiquimod maleate is an immune response modifier. It acts as a toll-like receptor 7 agonist. It is commonly used topically to treat warts on the skin of the genital and anal areas. It is also used to treat certain diseases of the skin, including skin cancers, such as basal cell carcinoma, Bowen's disease, superficial squamous cell carcinoma, some superficial malignant melanomas, and actinic keratosis. It can lead to the activation of Langerhans cells, which subsequently migrate to local lymph nodes to activate the adaptive immune system when applied to skin. Uses: Imiquimod maleat is commonly used topically to treat warts on the skin of the genital and anal areas. it is also used to treat certain diseases of the skin, including skin cancers, such as basal cell carcinoma, bowen's disease, superficial squamous cell carcinoma, some superficial malignant melanomas, and actinic keratosis. Synonyms: R 837 maleate; R837 maleate; R-837 maleate. Grades: >98%. CAS No. 896106-16-4. Molecular formula: C18H20N4O4. Mole weight: 356.38. | |
| Imiquimod maleate | Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 837 maleate. CAS No. 896106-16-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0180B. | |
| Imiquimod Related Compound A | a pharmacologically active compound related to Imiquimod. Synonyms: Desamino Imiquimod; 1-Isobutyl-1H-imidazo[4,5-c]quinoline; USP Imiquimod Related Compound A; 1-Isobutyl-1H-imidazo-[4,5-c]-quinoline. Grades: > 95%. CAS No. 99010-24-9. Molecular formula: C14H15N3. Mole weight: 225.30. | |
| Imiquimod Related Compound B | A pharmacologically active compound related to Imiquimod, a toll-like receptor 7 agonist used as an immune response modifier. Synonyms: Desamino Imiquimod N-Oxide; 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinoline 5-Oxide; 1-Isobutyl-1H-imidazo[4,5-c]quinoline N-Oxide; USP Imiquimod Related Compound B. Grades: > 95%. CAS No. 99010-63-6. Molecular formula: C14H15N3O. Mole weight: 241.30. | |
| Imiquimod Related Compound C | a pharmacologically active compound related to Imiquimod. Synonyms: 4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline, NSC 672965. Grades: > 95%. CAS No. 99010-64-7. Molecular formula: C14H14ClN3. Mole weight: 259.74. | |
| Imiquimod Related Compound D | a pharmacologically active compound related to Imiquimod. Synonyms: 1-Propyl-1H-imidazo[4,5-c]quinolin-4-amine; Desmethyl-N-propyl Imiquimod. Grades: > 95%. CAS No. 853792-81-1. Molecular formula: C13H14N4. Mole weight: 226.28. | |
| Imiquimod Related Compound E | a pharmacologically active compound related to Imiquimod. Synonyms: N4-Isobutylquinoline-3,4-diamine. Grades: > 95%. CAS No. 99010-09-0. Molecular formula: C13H17N3. Mole weight: 215.30. | |
| 2-Hydroxy Imiquimod | 1-(4-Amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol, has been shown to activate a toll-like receptor 7/8 Independent Cytokine, which can be used in the design of immunomodulating agents for use as vaccine adjuvants and anticancer treatments. Group: Biochemicals. Grades: Highly Purified. CAS No. 112668-45-8. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C14H16N4O. US Biological Life Sciences. | Worldwide |
| N-Formyl Imiquimod | N-Formyl Imiquimod is one of Imiquimod impurities, Imiquimod is an immune response modifier. It stimulates the production of interferon-a. Synonyms: N-[1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-yl]-formamide. CAS No. 910644-52-9. Molecular formula: C15H16N4O. Mole weight: 268.31. | |
| Gardiquimod | Immune response modifier. Antiviral and antitumor compound. Selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-kappaB in HEK 293 cells expressing TLR7 at 0.1ug/ml. 10 times more active than Imiquimod. At high concentrations (3ug/ml) slightly activates TLR8. Shows adjuvant activity to increase the effectiveness of vaccines. Group: Biochemicals. Alternative Names: 1- (4-Amino-2-ethylamino methyl imidazo [4, 5-c] quinolin-1-yl) -2- methyl propan-2-ol, 4-Amino-2-[(ethylamino)methyl]-?,?-dimethyl-1H-Imidazo[4,5-c]quinoline-1-ethanol. Grades: Highly Purified. CAS No. 1020412-43-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O. US Biological Life Sciences. | Worldwide |
| Gardiquimod TFA | Gardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier. The core structure is 1H-imidazo[4,5-c]quinoline, as found in related drugs such as imiquimod and resiquimod. It is structurally very similar to resiquimod differing only by an oxygen for nitrogen switch. Group: Others. Alternative Names: Gardiquimod TFA salt; Gardiquimod. CAS No. 1159840-61-5. Molecular formula: C19H24F3N5O3. Mole weight: 427.43. Appearance: Solid powder. Purity: >98%. IUPACName: 1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol 2,2,2-trifluoroacetate. Canonical SMILES: CC (O) (C)CN1C (CNCC)=NC2=C1C3=CC=CC=C3N=C2N. O=C (O)C (F) (F)F. Catalog: ACM1159840615. |  |
| Hyperforin dicyclohexylammonium salt | Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca 2+ levels by activating Ca 2+ -conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin dicyclohexylammonium salt modulates γδ T cells to secret IL-17α, improves Imiquimod (HY-B0180)-induced psoriasis-like mice model [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hyperforin DCHA. CAS No. 238074-03-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-116330A. | |
| RIPK1-IN-19 | RIPK1-IN-19 (compound 10b) is a selective RIPK1 inhibitor ( IC 50 =15 nM). RIPK1-IN-19 displays potent protective activity in TNFα-induced systemic inflammatory response syndrome (SIRS) model and Imiquimod (IMQ)-induced psoriasis model. RIPK1-IN-19 can be used in research on inflammation and immune system diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763831-43-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157456. | |
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