Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C14H16N4. CAS No. 99011-02-6. Prepack ID 40279313-1g. Molecular Weight 240.31. See USA prepack pricing.
Imiquimod
Cell-permeable. Topical immune response modifier that displays anti-angiogenic, anti-viral and anti-inflammatory properties. Up-regulates IL-18 and down-regulates MMP-9 through recognition of Toll-like receptor 7 (TLR7) and subsequent activation of MyD88-dependent pathway. Stimulates proinflammatory cytokine production interferon-alpha (IFN-alpha), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) and activates NF-kappaB. Caspase-3 activator that directly induces procaspase-3 cleavage. Anti-cancer compound. Apoptosis inducer. Antiproliferative, independent of immune system activation or function. Approved treatment for external genital warts caused by human papillomavirus infection. Group: Biochemicals. Alternative Names: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; R-837; S-26308. Grades: Highly Purified. CAS No. 99011-02-6. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C14H16N4. US Biological Life Sciences.
Worldwide
Imiquimod
Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 837. CAS No. 99011-02-6. Pack Sizes: 100 mg; 200 mg; 500 mg. Product ID: HY-B0180.
Imiquimod - CAS 99011-02-6
An imidazoquinoline compound that acts as a potent immunomodulator and displays anti-angiogenic, anti-viral and anti-inflammatory properties. Group: Fluorescence/luminescence spectroscopy.
Imiquimod-[d9]
Imiquimod-[d9] is a detuterated Imiquimod. Imiquimod is a medication of the immune response modifier class for the treatment of genital warts, superficial basal cell carcinoma, and actinic keratosis. Synonyms: Imiquimod-d9; 1-(2-(methyl-d3)propyl-1,1,2,3,3,3-d6)-1H-imidazo[4,5-c]quinolin-4-amine; 4-amino-1-isobutyl-1h-imidazo[4,5-c]quinoline-d9. Grade: > 95%. CAS No. 2712126-48-0. Molecular formula: C14H7N4D9. Mole weight: 249.36.
Imiquimod hydrochloride
Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 837 hydrochloride. CAS No. 99011-78-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0180A.
Imiquimod maleate
Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 837 maleate. CAS No. 896106-16-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0180B.
Imiquimod Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Imiquimod Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Imiquimod Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Imiquimod Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Imiquimod Related Compound E
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
2-Hydroxy Imiquimod
1-(4-Amino-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol, has been shown to activate a toll-like receptor 7/8 Independent Cytokine, which can be used in the design of immunomodulating agents for use as vaccine adjuvants and anticancer treatments. Group: Biochemicals. Grades: Highly Purified. CAS No. 112668-45-8. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C14H16N4O. US Biological Life Sciences.
Worldwide
Gardiquimod
Immune response modifier. Antiviral and antitumor compound. Selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-kappaB in HEK 293 cells expressing TLR7 at 0.1ug/ml. 10 times more active than Imiquimod. At high concentrations (3ug/ml) slightly activates TLR8. Shows adjuvant activity to increase the effectiveness of vaccines. Group: Biochemicals. Alternative Names: 1- (4-Amino-2-ethylamino methyl imidazo [4, 5-c] quinolin-1-yl) -2- methyl propan-2-ol, 4-Amino-2-[(ethylamino)methyl]-?,?-dimethyl-1H-Imidazo[4,5-c]quinoline-1-ethanol. Grades: Highly Purified. CAS No. 1020412-43-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O. US Biological Life Sciences.
Worldwide
Gardiquimod TFA
Gardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier. The core structure is 1H-imidazo[4,5-c]quinoline, as found in related drugs such as imiquimod and resiquimod. It is structurally very similar to resiquimod differing only by an oxygen for nitrogen switch. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Gardiquimod TFA salt; Gardiquimod. Product Category: Others. Appearance: Solid powder. CAS No. 1159840-61-5. Molecular formula: C19H24F3N5O3. Mole weight: 427.43. Purity: >98%. IUPACName: 1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol 2,2,2-trifluoroacetate. Canonical SMILES: CC(O)(C)CN1C(CNCC)=NC2=C1C3=CC=CC=C3N=C2N.O=C(O)C(F)(F)F. Product ID: ACM1159840615. Alfa Chemistry ISO 9001:2015 Certified. Categories: Gardiquimod trifluoroacetate.
Hyperforin dicyclohexylammonium salt
Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin dicyclohexylammonium salt modulates Ca 2+ levels by activating Ca 2+ -conducting non-selective canonical TRPC6 channels. Hyperforin dicyclohexylammonium salt also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin dicyclohexylammonium salt modulates γδ T cells to secret IL-17α, improves Imiquimod (HY-B0180)-induced psoriasis-like mice model [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hyperforin DCHA. CAS No. 238074-03-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-116330A.
RIPK1-IN-19
RIPK1-IN-19 (compound 10b) is a selective RIPK1 inhibitor ( IC 50 =15 nM). RIPK1-IN-19 displays potent protective activity in TNFα-induced systemic inflammatory response syndrome (SIRS) model and Imiquimod (IMQ)-induced psoriasis model. RIPK1-IN-19 can be used in research on inflammation and immune system diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763831-43-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157456.
Zabedosertib
Zabedosertib (BAY 1834845) is a selective, orally active IRAK4 inhibitor with immunomodulatory potential, IC50 is 3.55 nM. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors[1]. Zabedosertib exhibits anti-inflammatory property against IL-?, LPS (HY-D1056) and Imiquimod (HY-B1080) induced inflammation[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1834845. CAS No. 1931994-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139374.
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.