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| Product | Description | |
|---|---|---|
| Anti-Human Polyvalent Immunoglobulins (G,A,M)-FITC antibody produced in goat | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Anti-Human Polyvalent Immunoglobulins (whole molecule)?FITC antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Mouse Polyvalent Immunoglobulins (G,A,M)?FITC antibody produced in goat | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Human immunoglobulin for anticomplementary activity | Human immunoglobulin for anticomplementary activity. Uses: For analytical and research use. Group: European pharmacopoeia (ph. eur.); pharmacopoeial standards. Alternative Names: Human normal immunoglobulin for intravenous administration, ?-Blood globulins,?-Globulins, ?-Globulin, Globulins, ?-globulin, Blood plasma ?-globulins, Globulin, blood, ?-, Plasma ?-globulins, Human normal immunoglobulin, Gamma globulins, Globulin, blood, gamma-, Intacglobin, Blood gamma-globulin, Human normal immunoglobulin, Gamma- blood globulin, Globulins, ?-, conjugates, Globulins, blood-serum ?-, Globulins, ?-, Globulins, blood serum, ?-, Gamma globulin, Gamma- blood globulins. CAS No. 9007-83-4. Catalog: APS9007834B. Format: Neat. Shipping: +5°C. | |
| Monoclonal Anti-Rabbit Immunoglobulins?Alkaline Phosphatase antibody produced in mouse | clone RG-16, purified immunoglobulin, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-Rabbit Immunoglobulins-FITC antibody produced in mouse | clone RG-16, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Prepro-Killer Cell Immunoglobulin-Like Receptor 3DL3 (23-31) | Riteau et al. used rabbit antiserum to perform immunofluorescence analysis on the Prepro-Killer Cell Immunoglobulin-Like Receptor 3DL3 (23-31) corresponding to the N-terminal sequence of KIR2DL4. It did not differ between the p49 and KIR2DL4 receptor. Synonyms: KIR3DL3 (23-31) (human); H-Val-Gly-Gly-Gln-Asp-Lys-Pro-Phe-Leu-OH. Grade: ≥95%. Molecular formula: C44H69N11O13. Mole weight: 960.09. |  |
| 3-(Aminomethyl)-4-fluorophenol Hydrobromide | 3-(Aminomethyl)-4-fluorophenol Hydrobromide is derived from 2-Fluoro-5-methoxybenzaldehyde, which is versatile reactant used in the solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg. Molecular Formula: C7H8FNO; HBr, Molecular Weight: 141.148090999999. US Biological Life Sciences. |  Worldwide |
| AA 147 | AA 147 is an endoplasmic reticulum (ER) proteostasis regulator. Activates the ATF6 transcriptional program independently of ER stress and/or global UPR activation. Selectively reduces secretion of amyloidogenic transthyretin (TTR) from HepG2 cells. Reduces amyloidogenic immunoglobulin light chain (ALLC) secretion from ALMC-2 cells (EC50 = 1.1 μM). Synonyms: N-(2-Hydroxy-5-methylphenyl)benzenepropanamide; N-(2-hydroxy-5-methylphenyl)-3-phenylpropanamide. Grade: ≥98%. CAS No. 393121-74-9. Molecular formula: C16H17NO2. Mole weight: 255.31. | |
| Abagovomab | Abagovomab is a murine IgG1 monoclonal anti-idiotype antibody that functionally imitates the tumor-associated antigen, CA-125. Abagovomab has been used in the research of ovarian cancer treatment. Synonyms: Immunoglobulin G1, anti-(mouse oc 125) (mouse monoclonal aca-125 clone 3D5 gamma-chain), disulfide with mouse monoclonal aca-125 clone 3D5 kappa-chain, dimer. Grade: 95%. CAS No. 792921-10-9. | |
| AMP-224 | A fusion protein that contains the extracellular domain of PD-1 ligand 2 (B7-DC; PDCDILG2) and the Fc region of human immunoglobulin (Ig) G1. AMP-224 does not bind normal activated T-cells, but binds to PD-1 on chronically stimulated T-cells and reduces their proliferation. Synonyms: 2661380; AMP-244; GSK-2661380; AMP 244; GSK 2661380; AMP244; GSK2661380. | |
| Anti-ADORA2A antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-BCL2L2 antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-CACNG2 antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-CLK2 antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-CRK antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-CSF3R antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-CSF3R antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-CUGBP1 antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-CYP1A2 antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-EphB1 (ELK Receptor)-EXT antibody produced in sheep | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-GDNF antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-IFNGR1 antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-IL10RB antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-IL12RB1 antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-INHBB antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-LIN7A antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-PPP2R1A antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-PRKCH antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-RASSF5 antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-SUMO2 antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-THBS1 antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-TLE1 antibody produced in rabbit | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-V5 Agarose Affinity Gel antibody produced in mouse | purified immunoglobulin, clone V5-10. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-VIM antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-WWOX antibody produced in mouse | purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Arcitumomab | Arcitumomab is a humanized monoclonal antibody raised against human carcinoembryonic antigen (CEA). Arcitumomab is used as a diagnostic imaging agent for colorectal cancers. Synonyms: IMMU 4; CEA-Scan; Immunoglobulin G1, anti-(human carcinoembryonic antigen) Fab' fragment (mouse monoclonal IMMU-4 γ1-chain), disulfide with mouse monoclonal IMMU-4 light chain. Grade: 95%. CAS No. 154361-48-5. | |
| Ascorbyl Palmitate | Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C. Ascorbyl palmitate can be widely used in whitening, freckle removal, anti-aging, wrinkle removal, antioxidant and other functional cosmetics. It is relatively safe, can be used with confidence, generally does not affect pregnant women, no acne-causing. Ascorbyl palmitate is a potent antioxidant and non-acidic, stable form of vitamin C. It has all the physiological activities of vitamin C, which can play an anti-inflammatory role, reduce melanin production, promote immunoglobulin synthesis, prevent and treat pigmentation caused by trauma, sunburn, acne, etc., whiten skin, maintain skin elasticity, reduce wrinkles, improve skin roughness, pallor, slack and other phenomena, delay skin natural aging and photoaging. It is a highly effective antioxidant and oxygen-free radical scavenger with a neutral pH. Synonyms: L-Ascorbic Acid, 6-hexadecanoate; L-Ascorbic Acid, 6-Palmitate; Palmitic Acid, 6-Ester with Ascorbic Acid; 6-Hexadecanoyl-L-ascorbic Acid; 6-Monopalmitoyl-L-ascorbate; 6-O-Palmitoyl-L-ascorbic Acid; 6-O-Palmitoylascorbic Acid; 6-Palmitate-L-ascorbic Acid; 6-Palmitoylascorbic Acid; Ascorbic Acid 6-Palmitate; Ascorbic Acid Palmitate; Ascorbyl 6-Palmitate; L-Ascorbyl Palmitate; NSC 402451; Ondascora. Grade: >98%. CAS No. 137-66-6. Molecular formula: C22H38O7. Mole weight: 414.53. | |
| Aselizumab | Aselizumab. Synonyms: Aselizumab; Aselizumab [inn]; Bnp 001; Hudreg-55; Immunoglobulin G4, anti-(L-selectin) (human-mouse monoclonal hudreg-55 heavy chain), disulfide with human-mouse monoclonal hudreg-55 light chain, dimer. Grade: 95%. CAS No. 395639-53-9. | |
| Belrestotug | Belrestotug (EOS-448) is an antagonistic anti- TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EOS-448; EOS884448; GSK4428859A. CAS No. 2574438-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990032. |  |
| Bertilimumab | Bertilimumab is a human monoclonal antibody that targets eotaxin-1, a potent chemoattractant of eosinophils and important regulator of eosinophil overall function. Bertilimumab has the potential for the treatment of allergy disorders. Synonyms: CAT-213; CAT 213; CAT213; Human anti-eotaxin 1 monoclonal antibody; Immunoglobulin G4, anti-(human eotaxin 1) (human monoclonal cat-213 gamma 4-chain), disulfide with human monoclonal cat-213 kappachain, dimer. Grade: 95%. CAS No. 375348-49-5. | |
| Bertilimumab | Bertilimumab. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Bertilimumab;Bertilimumab [inn];Cat-213;Human anti-eotaxin 1 monoclonal antibody;Immunoglobulin G4, anti-(human eotaxin 1) (human monoclonal cat-213 gamma 4-chain), disulfide with human monoclonal cat-213 kappachain, dimer. Product Category: Heterocyclic Organic Compound. CAS No. 375348-49-5. Product ID: ACM375348495. Alfa Chemistry ISO 9001:2015 Certified. |  |
| BiP inducer X | BiP inducer X, a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78, is an effective ER (endoplasmic reticulum) stress inhibitor. BiP inducer X preferentially induces BiP with slight inductions of GRP94, calreticulin, and C/EBP homologous protein. BiP inducer X protects neurons from ER stress[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 101714-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110188. | |
| Bovine Colostrum Powder | Colostrum is a milky fluid that comes from the breasts of humans, cows, and other mammals the first few days after giving birth, before true milk appears. It contains proteins, carbohydrates, fats, vitamins, minerals, and proteins (antibodies) that fight disease-causing agents such as bacteria and viruses. Antibody levels in colostrums can be 100 times higher than levels in regular cows milk. Group: Others. Synonyms: Bovine Colostrum; Bovine Immunoglobulin; Bovine Lacteal Compounds; Calostro; Colostrum Bovin; Colostrum Bovin Hyperimmune; Cow Milk Colostrum; Goat Colostrum; Hyperimmune Bovine Colostrum; Immunoglobuline Bovine; Lait Colostral; Protogala. Appearance: Yellow powder. Source: Bovine. Bovine Colostrum Powder. Cat No: BCP-0100. |  |
| Camrelizumab | Camrelizumab is an anti-PD-1 immune checkpoint inhibitor that is being investigated for hepatocellular carcinoma and Hodgkin lymphoma. Camrelizumab is a humanized anti-PD-1 IgG4 antibody that blocks the binding of PD-L1 and PD-L2 to PD-1 with immune checkpoint inhibitory and antineoplastic activities. Synonyms: Immunoglobulin G4, anti-(cell surface receptor) (human-Mus musculus monoclonal SHR-1210 heavy chain), disulfide with human-Mus musculus monoclonal SHR-1210 light chain, dimer; AiRuiKa; HR 301210; Immunoglobulin G4, anti-(human programmed cell death protein 1) (human-Mus musculus monoclonal SHR-1210 heavy chain), disulfide with human-Mus musculus monoclonal SHR-1210 light chain, dimer; INCSHR 01210; INCSHR 1210; INCSHR01210; SHR 1210. Grade: ≥98%. CAS No. 1798286-48-2. | |
| Capromab Pendetide | Capromab Pendetide is a radioimmunoscintigraphic imaging agent composed of a murine monoclonal antibody and a substance targeting radioisotopes. Capromab Pendetide is used in the research of prostate cancer. Synonyms: CYT 356; OncoScint Prostate; Immunoglobulin G1, anti-(human prostatic carcinoma cell) (mouse monoclonal 7E11-C5.3 γ1-chain), disulfide with mouse monoclonal 7E11-C5.3 light chain, dimer, N6-[N-[2-[[2-[bis(carboxymethyl)amino]ethyl](carboxymethyl)amino]ethyl]-N-(carboxymethyl)glycyl]-N2-(N-glycyl-L-tyrosyl)-L-lysine conjugate. Grade: 95%. CAS No. 145464-28-4. | |
| CEP-11981 | CEP-11981 is an orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR) and Tie2 receptor tyrosine kinases with potential antiangiogenic and antineoplastic activities. Pan-VEGFR/Tie2 tyrosine kinase inhibitor CEP-11981 selectively binds to VEGFR and Tie2 receptor tyrosine kinases, which may result the inhibition of endothelial cell migration, proliferation and survival and the inhibition of tumor cell proliferation and tumor cell death. VEGFR and Tie2 are frequently overexpressed by a variety of tumor cell types and play crucial roles in the regulation of angiogenesis and the maintenance of tumor blood vessels. Tie2 (tyrosine kinase with immunoglobulin-like and EGF-like domains) is activated by angiopoietin-1 (Ang-1). Synonyms: CEP-11981; CEP 11981; CEP11981. CAS No. 856691-93-5. Molecular formula: C28H27N7O. Mole weight: 477.57. | |
| chymosin | Neonatal gastric enzyme with high milk clotting and weak general proteolytic activity, formed from prochymosin. Found among mammals with postnatal uptake of immunoglobulins. In peptidase family A1(pepsin A family). Group: Enzymes. Synonyms: rennin (but this should be avoided since it leads to confusion with renin). Enzyme Commission Number: EC 3.4.23.4. CAS No. 9001-98-3. Rennin. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4276; chymosin; EC 3.4.23.4; 9001-98-3; rennin (but this should be avoided since it leads to confusion with renin). Cat No: EXWM-4276. | |
| Cobolimab | Cobolimab is a monoclonal antibody directed against the inhibitory T-cell receptor, T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), with potential immune checkpoint inhibitory and antineoplastic activities. Cobolimab has the potential for the treatment of non-small cell lung cancer (NSCLC). Synonyms: TSR-022; TSR 022; TSR022; GSK-4069889; GSK 4069889; GSK4069889. Grade: 95%. CAS No. 2022215-65-0. | |
| Crizanlizumab | Crizanlizumab is a monoclonal antibody used for the prevention of vaso-occlusive crises (VOCs) in patients with sickle cell disease (SCD). Crizanlizumab binds to P-selectin, a cell adhesion molecule expressed on the surface of activated endothelial cells and platelets. By inhibiting P-selectin, crizanlizumab helps prevent the adhesion of sickle red blood cells to the endothelium and other blood cells, which is a key step in the initiation of VOCs in patients with SCD. It is indicated for the prevention of VOCs in patients with SCD. Vaso-occlusive crises are episodes of severe pain caused by the blockage of blood flow in small blood vessels, leading to tissue ischemia and organ damage. Crizanlizumab aims to reduce the frequency and severity of these painful episodes. Synonyms: Immunoglobulin G2, anti-(human P-selectin) (human-Mus musculus monoclonal SelG1 heavy chain), disulfide with human-Mus musculus monoclonal SelG1 light chain, dimer; Adakveo; Crizanlizumab-tmca; SEG 101; SelG 1. CAS No. 1690318-25-2. | |
| Dihydroberberine | Dihydroberberine is a naturally occurring isoquinoline alkaloid with anti-inflammatory, anti-atherosclerotic, hypolipidemic and anti-tumor activities. Dihydroberberine inhibits the human ether-related gene ( hERG ) channel and significantly reduces the expression of heat shock protein 90 ( Hsp90 ) and its interaction with hERG. Dihydroberberine also blocks the TLR4/MyD88/NF-κB signaling pathway to reduce pro-inflammatory cytokines and immunoglobulins, and has inhibitory effects on DSS (HY-116282C)-induced experimental colitis. Dihydroberberine also increases the sensitivity of lung cancer to sunitinib (HY-10255A), with synergistic efficacy [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 483-15-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1934. | |
| Dilpacimab | Dilpacimab (ABT165) is a potent dual-variable domain immunoglobulin, targets both delta-like ligand 4 (DLL4) and VEGF pathways. Dilpacimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABT165; PR1283233. CAS No. 1791420-09-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99852. | |
| Dilpacimab | Dilpacimab is a dual-variable domain immunoglobulin that targets delta-like ligand 4 (DLL4) and VEGF pathways. Dilpacimab has been used in the research of advanced solid tumors. Synonyms: ABT-165; ABT 165; ABT165. Grade: 95%. CAS No. 1791420-09-1. | |
| Dupilumab | Dupilumab, marketed under the brand name Dupixent, is a monoclonal antibody used to treat several chronic inflammatory conditions. It works by inhibiting the signaling of interleukin-4 (IL-4) and interleukin-13 (IL-13), which are cytokines involved in the inflammatory response. Dupilumab is approved for the treatment of several conditions, including, atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and eosinophilic esophagitis. Synonyms: Immunoglobulin, anti-(human interleukin 4 receptor α) (human REGN668 heavy chain), disulfide with human REGN668 κ-chain, dimer; Dupixent; REGN 668; SAR 231893. CAS No. 1190264-60-8. | |
| durvalumab | Durvalumab is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody. It was approved by FDA for the treatment of patients with locally advanced or metastatic urothelial carcinoma who have disease progression during or following platinum-containing chemotherapy, or whose disease has progressed within 12 months of receiving platinum-containing chemotherapy before or after surgery. Uses: The treatment of locally advanced or metastatic urothelial carcinoma. Synonyms: Imfinzi. CAS No. 1428935-60-7. Molecular formula: C6502H10018N1742O2024S42. Mole weight: 146.3. | |
| Efbemalenograstim alfa | Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Benegrastim; Bineuta; F 627. CAS No. 2200269-79-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99879. | |
| Elastase, Human leukocytes | Elastase, Human leukocytes is a serine protease present in the nitrogen-loving granules of neutrophils. Elastase, Human leukocytes potential substrates include almost all components of the extracellular matrix, as well as a variety of proteins such as coagulation factors, complement, immunoglobulins and cytokines. It has a strong proteolytic function and participates in the pathogenesis of inflammatory tissue damage [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9004-6-2. Pack Sizes: 1 U. Product ID: HY-P2751. | |
| Elotuzumab | Elotuzumab is a monoclonal antibody used in the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. It targets the SLAMF7 (Signaling Lymphocytic Activation Molecule Family member 7) protein found on the surface of myeloma cells and natural killer cells. Elotuzumab is typically used in combination with other drugs, such as lenalidomide and dexamethasone, to increase its effectiveness. It is administered via intravenous infusion and is used in patients who have received prior therapies for multiple myeloma. Synonyms: Elotuzumab (anti-SLAMF7); Immunoglobulin G1, anti-(human protein CS1) (human-mouse HuLuc63 heavy chain), disulfide with human-mouse HuLuc63 κ-chain, dimer; BMS 901608; Empliciti; HuLuc 63; PDL 063. CAS No. 915296-00-3. | |
| Endoproteinase Glu-C | Endoproteinase GluC (V8 protease) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: V8 protease; Glu-C. CAS No. 137010-42-5. Pack Sizes: 100 μg. Product ID: HY-E70194. | |
| Enibarcimab | Enibarcimab is a humanised murine monoclonal immunoglobulin G1 ( IgG1 ) antibody, could be used for acute heart failure, COVID-19 infections and septic shock research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2305638-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99177. | |
| Etanercept | Etanercept inhibits in vitro the activity of human TNF and is efficacious in many in vivo models of inflammation, including arthritis. Etanercept competitively inhibits the binding of both TNF-α and TNF-β (lymphotoxin-α) to cell surface TNF receptors, rendering TNF biologically inactive. It also modulates indirectly different biological responses that are induced or regulated by TNF, such as the expression of adhesion molecules E-selectin and to a lesser extent intercellular adhesion molecule 1 (ICAM-1), the production of interleukin-6 (IL-6) and matrix metalloproteinase 3 (MMP-3) (stromelysin), as well as IL1. Synonyms: 1-235-Tumor necrosisfactor receptor (human) fusion protein with 236-467-immunoglobulin G1 (human g1-chain Fc fragment); TNFR-Fc fusion protein; Etanercept; Embrel; Enbrel; rhu-TNFR-Fc. Grade: 95%. CAS No. 185243-69-0. Molecular formula: C2224H3472N618O701S36. | |
| Etentamig | Etentamig is a BCMA × CD3 bispecific T-cell engager (BiTE) that can inhibit the activity of B-cell maturation antigen ( BCMA ) and activate the T-cell surface glycoprotein CD3 complex. Etentamig can be used for research in multiple myeloma, immunoglobulin light chain amyloidosis, and cardiovascular diseases [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV-383; TNB 383B. CAS No. 2490552-52-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P990785. | |
| galiximab | Galiximab is a chimeric monoclonal antibody directed against CD80. Galiximab binds to CD80 and induces cross-linking of CD80 molecules and cell-death via ADCC. Galiximab has been investigated for the treatment of relapsed Hodgkin lymphoma. Synonyms: Anti-cd80 monoclonal antibody; Idec 114; Idec-114; Immunoglobulin G1, anti-(human cd80 (antigen)) (human-macaca irus monoclonal idec-114 heavy chain), disulfide with human-macaca irus monoclonal idec-114 lamda chain, dimer; Unii-S9o. Grade: 95%. CAS No. 357613-77-5. | |
| Galiximab | Galiximab (IDEC 114) is a primatized immunoglobulin G1 (IgG1) lambda monoclonal antibody directed against the CD80 antigen and blocks CD80 - CD28 binding. Galiximab has variable regions are primatized (cynomologous monkeys), and the constant regions are human. Galiximab can be used in research of B-cell lymphoma [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IDEC 114; Anti-Human CD80 Recombinant Antibody. CAS No. 357613-77-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99293. | |
| Gemtuzumab | Gemtuzumab (brand name Mylotarg) is a monoclonal antibody used in the treatment of acute myeloid leukemia (AML). Gemtuzumab targets CD33, a protein found on the surface of myeloid cells, including leukemic cells in AML. By binding to CD33, gemtuzumab may induce antibody-dependent cellular cytotoxicity (ADCC), leading to destruction of CD33-positive leukemia cells. Gemtuzumab is indicated for the treatment of newly diagnosed CD33-positive AML in adults, as well as for relapsed or refractory CD33-positive AML in both adults and pediatric patients. Synonyms: Immunoglobulin G4, anti-(human CD33 antigen) (human-mouse monoclonal hP67.6 γ4-chain)), disulfide with human-mouse monoclonal hP67.6 κ-chain, dimer; hP67.6. CAS No. 2924764-21-4. | |
| Gemtuzumab ozogamicin | Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220578-59-6. Pack Sizes: 100 μg; 200 μg; 500 μg. Product ID: HY-109539. | |
| Golimumab | Golimumab is a monoclonal antibody used in the treatment of autoimmune diseases, particularly rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. Golimumab targets and inhibits tumor necrosis factor alpha (TNF-α), a cytokine involved in the inflammatory pathway that contributes to autoimmune diseases. By blocking TNF-α, golimumab helps to reduce inflammation and alleviate symptoms associated with these conditions. Synonyms: Immunoglobulin G1, anti-(human tumor necrosis factor α) (human monoclonal CNTO 148 γ1-chain), disulfide with human monoclonal CNTO 148 κ-chain, dimer; CNTO 148; rTNV148B; Simponi; Simponi aria; Symponi; TNV 148B. CAS No. 476181-74-5. | |
| Hyaluronidase, Ovine testes | Hyaluronidase, Ovine testes is an enzyme responsible for catalyzing the degradation of hyaluronic acid. It is used to improve the absorption and dispersion of gastrointestinal fluids, drugs, and contrast agents. Hyaluronidase, Ovine testes can enhance the diffusion or delivery of local agent (LA) that can suppress or relieve pain or immunoglobulins (Igs) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37326-33-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108903A. | |
| Ifinatamab | Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2484870-90-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99367. | |
| IgA, Kappa from murine myeloma | clone TEPC 15, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
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