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Indinavir is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Indinavir is used as an antiviral. Group: Biochemicals. Alternative Names: 2, 3, 5-Trideoxy-N-[ (1S, 2R) -2, 3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[ (2S) -2[[ (1, 1-dimethylethyl) amino]carbonyl]-4- (3-pyridinylmethyl) -1-piperazinyl]-2- (phenylmethyl) -D-erythro-pentonamide; [1 (1S, 2R) , 5 (S) ]-2, 3, 5-Trideoxy-N- (2, 3-dihydro-2-hydroxy-1H-inden-1-yl) -5-[2-[[ (1, 1-dimethylethyl) amino]carbonyl]-4- (3-pyridinylmethyl) -1-piperazinyl]-2- (phenylmethyl) -D-erythro-pentonamide; Compound J. Grades: Highly Purified. CAS No. 150378-17-9. Pack Sizes: 10mg. US Biological Life Sciences.
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Indinavir
Indinavir is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Indinavir is used as an antiviral. Uses: Hiv protease inhibitors. Synonyms: Crixivan; MK-639; L-735524; MK639; L735524; MK 639; L 735524. Grades: >98%. CAS No. 150378-17-9. Molecular formula: C36H47N5O4. Mole weight: 613.79.
Indinavir
Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a K i of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CL pro inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-639 free base; L-735524 free base. CAS No. 150378-17-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0689.
Indinavir-d6
Member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Antiviral. Group: Biochemicals. Alternative Names: 2, 3, 5-Trideoxy-N-[ (1S, 2R) -2, 3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[ (2S) -2[[ (1, 1-dimethylethyl) amino]carbonyl]-4- (3-pyridinylmethyl-d6) -1-piperazinyl]-2- (phenylmethyl) -D-erythro-pentonamide. Grades: Highly Purified. CAS No. 185897-02-3. Pack Sizes: 1mg. US Biological Life Sciences.
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Indinavir sulfate
Indinavir is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV infection and AIDS. It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM. However, indinavir demonstrates up to a 50-fold loss in potency against the HIV-1 protease drug-resistant mutations PRL24I, PRI50V, and PRG73S (Kis = 1.4, 27, and 0.55 nM). Uses: Hiv protease inhibitors. Synonyms: Crixivan sulfate; MK-639 sulfate; L-735524 sulfate; MK639 sulfate; L735524 sulfate; MK 639 sulfate; L 735524 sulfate. Grades: >98%. CAS No. 157810-81-6. Molecular formula: C36H49N5O8S. Mole weight: 711.87.
Indinavir sulfate
Indinavir sulfate (MK-639) is an orally active and selective HIV-1 protease inhibitor with a K i of 0.54 nM for PR. Indinavir sulfate exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir sulfate is also a SARS-CoV 3CL pro inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-639; L735524. CAS No. 157810-81-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0689A.
Indinavir Sulfate (MK-639, Crixivan)
Indinavir Sulfate is a member of the novel hydroxyaminopentane amide class of HIV-1 protease inhibitors. Antiviral. It is a COVID19-related research product. Group: Biochemicals. Alternative Names: 2, 3, 5-Trideoxy-N-[ (1S, 2R) -2, 3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[ (2S) -2[[ (1, 1-dimethylethyl) amino]carbonyl]-4- (3-pyridinylmethyl) -1-piperazinyl]-2- (phenylmethyl) -D-erythro-pentonamide; MK-639; Crixivan. Grades: Highly Purified. CAS No. 157810-81-6. Pack Sizes: 5mg, 25mg, 50mg, 100mg. Molecular Formula: C36H47N5O4 H2SO4, Molecular Weight: 711.87. US Biological Life Sciences.
Worldwide
Des-3-pyridylmethyl indinavir
Des-3-pyridylmethyl indinavir. Group: Biochemicals. Alternative Names: 2, 3, 5-Trideoxy-N-[ (1S, 2R) -2, 3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[ (2S) -2-[[ (1, 1-dimethylethyl) amino]carbonyl]-1-piperazinyl]-2- (phenylmethyl) -D-erythro-pentonamide. Grades: Highly Purified. CAS No. 150323-38-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C30H42N4O4. US Biological Life Sciences.
Worldwide
Des-3-pyridylmethyl indinavir(>90%)
Des-3-pyridylmethyl indinavir(>90%). Uses: Designed for use in research and industrial production. Additional or Alternative Names: [1(1s,2r),5(S)]-2,3,5-Trideoxy-N-(2,3-Dihydro-2-Hydroxy-1h-Inden-1-Yl)-5-[2-[[(1,1-Dimethyl)Amino]Carbonyl]-1-Piperazinyl]-2-(Phenylmethyl)-D-Erythro-Pentonamide;[1(1S,2R),5(S)]-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-[2-[[(1,1-dimethyle. Appearance: Light brown solid. CAS No. 150323-38-9. Molecular formula: C30H42N4O4. Mole weight: 522.68. Purity: 0.96. IUPACName: (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5-[[(1S,2R)-2-hydroxy-2,3-dihydro-1. Density: 1.22. Product ID: ACM150323389. Alfa Chemistry ISO 9001:2015 Certified.
Des(3-pyridylmethyl tert-Butylaminocarbonyl) Indinavir is an analogue of Indinavir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Atazanavir
Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with inhibition constant Ki of 66 nmol/L and also inhibits the viral replication of HIV-1 with 50% effective concentration EC50 ranging from 2.6 to 5.3 nmol/L. Atazanavir binds to HIV-1 protease preventing the cleavage of gag and gag-pol polyproteins, which results in the formation of immature virions in HIV-1-infected cells. Atazanavir has a different C-2 symmetric chemical structure and a generally greater antiretroviral potency in various HIV strains compared to other protease inhibitors, including indinavir, nelfinavir, ritonavir, saquinavir and amprenavir. Synonyms: Atazanavir ; Reyataz ; Atazanavir sulfate ; CGP75136 ; CGP75176 ; CGP75355 ; BMS232632 ; CGP 73547 ; CGP 75136 ; CGP 75176 ; CGP 75355 ; CGP-73547 ; CGP-75136 ; CGP-75176 ; CGP-75355 ; BMS 232632 ; BMS-232632 ; BMS-232632-05 ; C413408. Grades: 0.98. CAS No. 198904-31-3. Molecular formula: C38H52N6O7. Mole weight: 704.869.
Brecanavir
Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir. Brecanavir is by a substantial margin the most potent and broadly active antiviral agent among the PIs tested in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Brecanavir; GW-0385; GW-0385; GW0385; GW-640385; GW 640385; GW640385; GW-640385X; VX-385; VX 385; VX385. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 313682-08-5. Molecular formula: C33H41N3O10S2. Mole weight: 703.82. Purity:>98%. IUPACName: [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate. Canonical SMILES: Cc1nc(cs1)COc2ccc(cc2)C[C@@H]([C@@H](CN(CC(C)C)S(=O)(=O)c3ccc4c(c3)OCO4)O)NC(=O)O[C@H]5CO[C@@H]6[C@H]5CCO6. Product ID: ACM313682085-1. Alfa Chemistry ISO 9001
Brecanavir
Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir. Uses: Hiv-1 protease inhibitor. Synonyms: Brecanavir; UNII-E367I8C7FI; CHEMBL206031; GW-0385; GW-640385; GW-640385X; VX-385; GW0385; GW640385; GW640385X; VX385; GW 0385; GW 640385; GW 640385X; VX 385; [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate. Grades: ≥98%. CAS No. 313682-08-5. Molecular formula: C33H41N3O10S2. Mole weight: 703.82.
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