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25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H16ClNO4. CAS No. 53-86-1. Prepack ID 62725591-25g. Molecular Weight 357.79. See USA prepack pricing.
Indomethacin
Indomethacin. Group: Biochemicals. Grades: Purified. CAS No. 53-86-1. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Indomethacin
Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC 50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Indometacin. CAS No. 53-86-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-14397.
Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD. Group: Biochemicals. Alternative Names: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
A cell-permeable, bioavailable 2-trifluoromethyl analog of Indomethacin that acts as a highly potent, time-dependent inhibitor of cyclooxygenase -2 (COX-2; IC50=267 and 388nM for mouse and human COX-2, respectively) and its several mutant forms. Does not affect COX-1 activity even at high concentrations (IC50 >100uM). Interacts with human COX-2 with much greater affinity than indomethacin (KI = 1.5 vs 13uM) and blocks COX-2 dependent arachidonic acid oxygenation (IC50 = 150nM in 1483 human head and neck squamous cell carcinoma cells). Further, minimizes swelling in carrageenan-induced rat paw edema model (EC50 = 1.7mg/kg, p.o.) with no gastrointestinal bleeding at higher doses (10mg/kg). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Indomethacin Acyl-b-D-glucuronide
Indomethacin Acyl-b-D-glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Indomethacin acyl glucuronide
a metabolite of Indomethacin. Synonyms: 1-[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate] β-D-Glucopyranuronic Acid; Indomethacin Glucuronide. Grades: > 95%. CAS No. 75523-11-4. Molecular formula: C25H24ClNO10. Mole weight: 533.91.
Nonsteroidal anti-inflammatory agent (NSAID). Group: Biochemicals. Alternative Names: 1-(4-Chlorobenzoyl-d4)-5-methoxy-2-methyl-1H-indole-3-acetic Acid; Indometacin-d4; Bonidon-d4; Catlep-d4; Indomethine-d4; Inacid-d4; Indomod-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Indomethacin-d4 Methyl Ester
Labeled selective COX-2 inhibitor. Group: Biochemicals. Alternative Names: 1-(4-(Chlorobenzoyl-d4))-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester; Methyl N-(p-Chlorobenzoyl-d4)-2-methyl-5-methoxy-3-indolylacetate; L 588983-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Indomethacin Diamide
Indomethacin Diamide. Group: Biochemicals. Alternative Names: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-Indole-3-acetic Acid 2- (4-chlorobenzoyl) -2- (4-methoxyphenyl) hydrazide. Grades: Highly Purified. CAS No. 402849-25-6. Pack Sizes: 10mg. Molecular Formula: C33H27Cl2N3O5, Molecular Weight: 616.49. US Biological Life Sciences.
Worldwide
Indomethacin EP impurity C
Indomethacin EP impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4018-82-0. Molecular Formula: C14H12ClNO2. Mole Weight: 261.71. Catalog: APB4018820.
Indomethacin EP impurity D
Indomethacin EP impurity D. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H16ClNO4. Mole Weight: 357.79. Catalog: APB11141.
Indomethacin EP impurity E
Indomethacin EP impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 807614-94-4. Molecular Formula: C19H16ClNO4. Mole Weight: 357.79. Catalog: APB807614944.
Indomethacin EP impurity F
Indomethacin EP impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 402849-27-8. Molecular Formula: C21H16Cl2N2O3. Mole Weight: 415.27. Catalog: APB402849278.
Indomethacin EP impurity G
Indomethacin EP impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 402849-26-7. Molecular Formula: C19H15Cl2NO4. Mole Weight: 392.23. Catalog: APB402849267.
Indomethacin EP impurity H
Indomethacin EP impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1601-18-9. Molecular Formula: C20H18ClNO4. Mole Weight: 371.82. Catalog: APB1601189.
Indomethacin EP impurity I
Indomethacin EP impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 16401-99-3. Molecular Formula: C21H20ClNO4. Mole Weight: 385.84. Catalog: APB16401993.
Indomethacin EP impurity J
Indomethacin EP impurity J. Uses: For analytical and research use. Group: Impurity standards. CAS No. 402849-25-6. Molecular Formula: C33H27N3O5. Mole Weight: 616.5. Catalog: APB402849256.
Indomethacin Ethyl Ester
an impurity of Indomethacin. Synonyms: Ethyl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate. Grades: > 95%. CAS No. 16401-99-3. Molecular formula: C21H20ClNO4. Mole weight: 385.85.
Indomethacin heptyl ester
Indomethacin heptyl ester is a potent, non-selective COX-2 inhibitor. Synonyms: 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid, 1-heptyl ester. CAS No. 282728-47-6. Molecular formula: C26H30ClNO4. Mole weight: 456.
Indomethacin Impurity D
an impurity of Indomethacin. Synonyms: 4-Dechloro-2-chloroindomethacin; [1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic Acid; 1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-acetic Acid. Grades: > 95%. Molecular formula: C19H16ClNO4. Mole weight: 357.80.
Indomethacin Impurity E
an impurity of Indomethacin. Synonyms: 1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid; [1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic Acid; 4-Dechloro-3-chloroindomethacin. Grades: > 95%. CAS No. 807614-94-4. Molecular formula: C19H16ClNO4. Mole weight: 357.80.
Indomethacin Impurity F
An impurity of the anti-inflammatory drug indomnethacin. Synonyms: 4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid. Grades: > 95%. CAS No. 402849-27-8. Molecular formula: C21H16Cl2N2O3. Mole weight: 415.28.
Indomethacin Impurity G
an impurity of Indomethacin. Synonyms: 3,4-Dichloroindometacin ([1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic Acid) - See more at: http://us.lgcstandards.com/SV/en/3-4-Dichloroindometacin-1-3-4-Dichlorobenzoyl-5-methoxy-2-methylindol-3-yl-acetic-Acid-/p/MM0584.02#sthash.3kNV9RgG. Grades: > 95%. CAS No. 402849-26-7. Molecular formula: C19H15Cl2NO4. Mole weight: 392.24.
Indomethacin Impurity J (Indomethacin Diamide)
an impurity of Indomethacin. Synonyms: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-Indole-3-acetic Acid 2-(4-chlorobenzoyl)-2-(4-methoxyphenyl)hydrazide, Indomethacin Impurity J. Grades: > 95%. CAS No. 402849-25-6. Molecular formula: C33H27Cl2N3O6. Mole weight: 616.51.
Indomethacin methyl ester
Indomethacin methyl ester is an impurity of Indomethacin. Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory activity and chemopreventive properties. Synonyms: Indomethacin, Methylated; Methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate; Methyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate; EINECS 216-494-8; BRN 0496619. CAS No. 1601-18-9. Molecular formula: C20H18ClNO4. Mole weight: 371.817.
Indomethacin Methyl Ester
Selective COX-2 inhibitor. Group: Biochemicals. Alternative Names: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester; Methyl N-(p-Chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetate; L 588983. Grades: Highly Purified. CAS No. 1601-18-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Indomethacin Morpholinylamide
BML-190 is a selective cannabinoid CB2 receptor inverse agonist with Ki of 435 nM, with 50-fold selectivity over CB1 receptor. Synonyms: BML-190; BML 190; BML190; LM-4131; LM4131; LM 4131; IMMA; Indomethacin Morpholinylamide; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1-[2-(4-morpholinyl)-2-oxoethyl]-1H-indole. Grades: >98%. CAS No. 2854-32-2. Molecular formula: C23H23ClN2O4. Mole weight: 426.89.
Indomethacin N-octyl amide
Indomethacin N-octyl amide is a derivative of indomethacin, a non-selective, reversible, and competitive inhibitor of COX-1 and -2 with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Synonyms: 2-(1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-N-octylacetamide. Grades: ≥98%. CAS No. 282728-65-8. Molecular formula: C27H33ClN2O3. Mole weight: 469.
Indomethacin sodium
Indomethacin (Indometacin) sodium is a potent, orally active COX1/2inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium has anticancer activity and anti-infective activity. Indomethacin sodium can be used for cancer, inflammation and viral infection research. Group: Inhibitors. Alternative Names: 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-aceticacisodiumsalt; 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-indole-3-aceticacisodiumsalt; osmosin; sodium1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetate; sodiumindomethacin; INDOMETHACIN SODIUM;1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid sodium salt;IndoMetacine sodiuM. CAS No. 7681-54-1. Molecular formula: C19H15ClNNaO4. Mole weight: 379.77. Catalog: ACM7681541.
Indomethacin sodium hydrate
Indomethacin (Indometacin) sodium hydrateis a potent, orally active COX1/2 inhibitor with IC 50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium hydrateis has anticancer activity and anti-infective activity. Indomethacin sodium hydrateis can be used for cancer, inflammation and viral infection research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Indometacin sodium hydrate. CAS No. 74252-25-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-14397A.
N-(2-phenylethyl)-Indomethacin amide
A potent elective reversible inhibitor of COX-2. Synonyms: N-(2-phenylethyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide; N-2PIA. CAS No. 261766-32-9. Molecular formula: C27H25ClN2O3. Mole weight: 461.
N- (2-Phenylethyl) indomethacin amide
N- (2-Phenylethyl) indomethacin amide. Group: Biochemicals. Alternative Names: N-(2-Phenylethyl)-1-p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetamide; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-N-(2-phenylethyl)-1H-indole-3-acetamide. Grades: Highly Purified. CAS No. 261766-32-9. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C27H25ClN2O3. US Biological Life Sciences.
An aromatic amide of indomethacin recently reported to be a potent and selective reversible inhibitor of COX-2. Inhibits human recombinant and ovine COX-2 with IC50 of 0.06 uM and 0.125 uM, respectively. Group: Biochemicals. Alternative Names: N-(2-Phenylethyl)-1-p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetamide. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
N-(3-pyridyl)-Indomethacin amide
N-(3-pyridyl)-Indomethacin amide is a potent and selective reversible inhibitor of COX-2. Synonyms: N-(3-pyridyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide; N-3PyIA. CAS No. 261766-29-4. Molecular formula: C24H20ClN3O3. Mole weight: 433.9.
N-(3-Pyridyl)indomethacin amide
N-(3-Pyridyl)indomethacin amide. Group: Biochemicals. Alternative Names: N-(3-Pyridyl)-1-p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetamide; 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-N-3-pyridinyl-1H-indole-3-acetamide. Grades: Highly Purified. CAS No. 261755-29-4. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C24H20ClN3O3. US Biological Life Sciences.
An aromatic amide of indomethacin recently reported to be a potent and selective reversible inhibitor of COX-2. Inhibits human recombinant COX-2 with IC50 of 0.1 uM. Group: Biochemicals. Alternative Names: N-(3-Pyridyl)-1-p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetamide. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
N-(4-acetamidophenyl)-Indomethacin amide
An elective reversible inhibitor of COX-2. Synonyms: N-(4-acetamidophenyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide; N-4AIA. CAS No. 261766-23-8. Molecular formula: C27H24ClN3O4. Mole weight: 490.
N- (4-Acetamidophenyl) indomethacin amide
N- (4-Acetamidophenyl) indomethacin amide. Group: Biochemicals. Alternative Names: N-(4-Acetamidophenyl)-1-p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetamide. Grades: Highly Purified. CAS No. 261766-23-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C27H24ClN3O4. US Biological Life Sciences.
An aromatic amide of indomethacin recently reported to be a potent and selective reversible inhibitor of COX-2. Inhibits human recombinant and ovine COX-2 with IC50 of 0.1 uM and 0.625 uM, respectively. Group: Biochemicals. Alternative Names: N-(4-Acetamidophenyl)-1-p-chlorobenzoyl-5-methoxy-2-methylindole-3-acetamide. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
N-Deschlorobenzoyl Indomethacin
A metabolite of Indomethacin. Group: Biochemicals. Alternative Names: 5-Methoxy-2-methyl-1H-indole-3-acetic Acid; 2-Methyl-5-methoxy-3-indolylacetic Acid; De (chlorobenzoyl) indomethacin; N-Des (4-chlorobenzoyl) indomethacin; NSC 97026;DBI. Grades: Highly Purified. CAS No. 2882-15-7. Pack Sizes: 10mg. US Biological Life Sciences.
The major metabolite of Indomethacin. Group: Biochemicals. Alternative Names: 1-(4-Chlorobenzoyl)-5-hydroxy-2-methyl-1H-indole-3-acetic Acid; 5-Hydroxyindomethacin; Demethylindomethacin; Desmethylindomethacin. Grades: Highly Purified. CAS No. 2504-32-7. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
O-Desmethyl Indomethacin
The major metabolite of Indomethacin. Synonyms: 1-(4-Chlorobenzoyl)-5-hydroxy-2-methyl-1H-indole-3-acetic Acid; 5-Hydroxyindomethacin; Demethylindomethacin; Desmethylindomethacin. Grades: > 95%. CAS No. 2504-32-7. Molecular formula: C18H14ClNO4. Mole weight: 343.77.
O-Desmethyl Indomethacin-d4
The major labeled metabolite of Indomethacin. Group: Biochemicals. Alternative Names: 1-(4-Chlorobenzoyl-d4)-5-hydroxy-2-methyl-1H-indole-3-acetic Acid; 5-Hydroxy-indomethacin-d4; Demethylindomethacin-d4; Desmethylindomethacin-d4. Grades: Highly Purified. CAS No. 1189916-55-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
O-Desmethyl-N-deschlorobenzoyl Indomethacin
A metabolite of Indomethacin. Group: Biochemicals. Alternative Names: 5-Hydroxy-2-methyl-1H-indole-3-acetic Acid; DMBI. Grades: Highly Purified. CAS No. 50995-53-4. Pack Sizes: 10mg. US Biological Life Sciences.
1-(2-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 4-Dechloro-2-chloroindomethacin (D226240), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). Group: Biochemicals. Grades: Highly Purified. CAS No. 1568-35-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H18ClNO4. US Biological Life Sciences.
1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 3-Chloroindomethacin (C367395), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). Group: Biochemicals. Grades: Highly Purified. CAS No. 942431-82-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H17Cl2NO4, Molecular Weight: 406.26. US Biological Life Sciences.
1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 4-Dechloro-3-chloroindomethacin (D226245), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). Group: Biochemicals. Grades: Highly Purified. CAS No. 1568-36-1. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H18ClNO4. US Biological Life Sciences.
Worldwide
2-(4-Methoxyphenyl)hydrazinesulfonic acid sodium salt monohydrate
Intermediate of Indomethacin. Synonyms: sodium;N-(4-methoxyanilino)sulfamate. Grades: > 95 %. CAS No. 5446-7-1. Molecular formula: C7H9N2NaO4S · H2O. Mole weight: 258.23.
4-Methoxyphenylhydrazine hydrochloride
4-Methoxyphenylhydrazine hydrochloride is an intermediate of Indomethacin, which is a non-steroidal anti-inflammatory drug used in the treatment of musculoskeletal and joint disorders, including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. Synonyms: Hydrazine, (4-methoxyphenyl)-, hydrochloride (1:x); Hydrazine, (4-methoxyphenyl)-, hydrochloride. Grades: ≥95%. CAS No. 70672-74-1. Molecular formula: C7H10N2O.xHCl. Mole weight: 138.17 (free base).
4-Oxocyclohexane carboxylic Acid
4-Oxocyclohexane carboxylic Acid is used in the preparation of Indomethacin (I641000) analogues used in the treatment of prostate cancer. In addition it is used in the synthesis of β-alanine derivatives as glucagon receptor antagonists. Group: Biochemicals. Alternative Names: 4-Ketocyclohexane carboxylic Acid; 4-Ketocyclohexyl carboxyl ic Acid; 4-Oxo-1-cyclohexanecarboxylic Acid; 4-Oxocyclohexane carboxylic Acid; Cyclohexanone-4-carboxylic Acid. Grades: Highly Purified. CAS No. 874-61-3. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Adapalene
Adapalene is more active than indomethacin, betamethasone valerate, tretinoin, isotretinoin or etretinate in inhibiting lipoxygease activity, but it has little activity against cyclo-oxygenase. Synonyms: ADAPALENE; Differin; Adaferin; Adapaleno; Adapalenum; CD-271; CD271; CD 271. Grades: >98%. CAS No. 106685-40-9. Molecular formula: C28H28O3. Mole weight: 412.52.
Alaptide
Permeation of Indomethacin through Skin Using Nanonized Alaptide. Synonyms: Cyclo(1-amino-1-cyclopentanecarbonyl-L-alanyl). Grades: > 95%. CAS No. 90058-29-0. Molecular formula: C9H14N2O2. Mole weight: 182.22.
α-Glucametacin-d4
Labelled α-Glucametacin. A nonsteroidal anti-inflammatory analgesic. An indomethacin conjugates with D-glucosamine was prepared for reducing ulcerogenic potency, increasing the bioavailability of indomethacin and exerting the coordinative effects on osteoarthritis. Synonyms: 2-[[[1-(4-Chlorobenzoyl-d4)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-α-D-Glucopyranose; α-Glucametacine-d4; α-Glucamethacin-d4; α-Indomethacin-d4 Glucosamide. Molecular formula: C25H23D4ClN2O8. Mole weight: 522.97.
Clometacin-d4
Clometacin-d4 is the labeled analogue of Clometacin (C586995), an antalgic drug that binds to human serum albumin (HSA) and inhibits the binding of indomethacin, warfarin, clofibrate and salicylic acid to HSA. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H12D4ClNO4, Molecular Weight: 361.81. US Biological Life Sciences.
Worldwide
Indometacin sodium
Indomethacin sodium is the sodium salt of indomethacin, a non-selective, reversible, and competitive inhibitor of COX-1 and -2 with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Synonyms: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid sodium salt. Grades: ≥98% (HPLC). CAS No. 74252-25-8. Molecular formula: C19H21ClNNaO7. Mole weight: 433.82.
Ketorolaco
Ketorolaco is a potent, short acting nonsteroidal antiinflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It is a pyrrolizine carboxylic acid derivative structurally related to indomethacin. It is used as an analgesic. It acts by inhibiting the bodily synthesis of prostaglandins. It is also used to treat eye pain and to relieve the itchiness and burning of seasonal allergies. It was developed in 1989 by Syntex Corp. Uses: Ketorolaco is used as an analgesic. it is also used to treat eye pain and to relieve the itchiness and burning of seasonal allergies. Synonyms: ketorolac; Macril; (+-)-Ketorolac; 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-; Toradol. Grades: 98%. CAS No. 66635-83-4. Molecular formula: C15H13NO3. Mole weight: 255.27.
Lubiprostone
Lubiprostone (SPI-0211; RU0211) increases intestinal fluid secretion through generation of CIC-2 / CFTR and activation of cAMP signaling pathway. Lubiprostone inhibits myeloperoxidase (MPO) activity, downregulates Indomethacin (HY-14397)-induced iNOS and TNFα expression. Lubiprostone can be used for chronic constipation research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU-0211; SPI-0211. CAS No. 136790-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0679.
m-Carborane-1-carboxylic Acid
m-Carborane-1-carboxylic Acid is used as a reactant or reagent in the synthetic preparation of ortho-carbaborane indomethacin pharmacophores as selective COX-2 enzyme inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 18581-81-2. Pack Sizes: 15mg, 30mg. Molecular Formula: C3H12B10O2, Molecular Weight: 188.24. US Biological Life Sciences.
Worldwide
Methyl 5-Methoxy-2-methylindole-3-acetate
Intermediate in the preparation of Indomethacin. Group: Biochemicals. Alternative Names: 5-Methoxy-2-methyl-. Grades: Highly Purified. CAS No. 7588-36-5. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Nonsteroidal Anti-Inflammatory Compound Library
A unique collection of 530 nonsteroidal anti-inflammatory related compounds can be used for HTS and HCS; - Contains common NSAIDs, such as aspirin, indomethacin, ibuprofen, Sulindac, Piroxicam, etc. ?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4710. Categories: Nonsteroidal Anti-Inflammatory Compounds Libraries.
Polyoxyl (40) Stearate
Polyoxyl (40) Stearate. Synonyms: polyoxyethylene (40) monostearate. CAS No. 9004-99-3. Product ID: PE-0536. Molecular formula: C17H35COO(CH2 CH2O)nH. Category: Solvent-enhancing; Emulsifier. Product Keywords: Solubilizer Excipients; Emulsifier Excipients; PE-0536; Polyoxyl (40) Stearate; Solvent-enhancing; Emulsifier; C17H35COO(CH2 CH2O)nH; 9004-99-3. UNII: NA. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Keep in a cool, dry place. Source and Preparation: Stearate polyhydroxy 40 ester is mainly used as a suppository substrate, such as medrol, progesterone, chlorhexidine, indomethacin, etc. It can be used as the substrate and emulsifier of ointment to increase the decomposition and bioavailability of drugs, so as to make the appearance of ointment more delicate, white and emulsified evenly. Polyhydrocarbon oxy40 stearate can also be used as the matrix of dripping pills, and the dissolution of drugs in the dispersing system and the solubilization of drugs in the dissolution are superior. Stearate polyhydrocarbon oxy40 ester is used in the cosmetic industry as cream, conditioner and other oil-in-water products.
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