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| Product | Description | |
|---|---|---|
| Insulin-Like Growth Factor Binding Protein-2 from mouse | ?95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. |  |
| Insulin-Like Growth Factor Binding Protein-2 human | recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Insulin-Like Growth Factor Binding Protein-3 human | recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture, ?95% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Insulin-like Growth Factor Binding Protein-5 human | >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Insulin-like Growth Factor-I (E3R) human | >95% (HPLC), recombinant, expressed in E. coli, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Insulin-like Growth Factor-I from mouse | IGF-I, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Insulin-like Growth Factor-I human | IGF-I, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Insulin-like Growth Factor-II from mouse | IGF-II, recombinant, expressed in E. coli, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Insulin-like Growth Factor-II human | IGF-II, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Insulin-like growth factor-II mRNA binding protein 3 (199-207) | Insulin-like growth factor-II mRNA binding protein 3 (199-207) is amino acids 199 to 207 fragment of Insulin-like growth factor-II mRNA binding protein 3. IGF2BP3 is an oncofetal RNA-binding protein that regulates targets such as insulin-like growth factor-2 (IGF-2) and ACTB (beta-actin). Synonyms: IGF2BP3 (199-207); IMP3 (199-207); KOC (199-207). |  |
| Insulin-like growth factor-II mRNA binding protein 3 (515-523) | Insulin-like growth factor-II mRNA binding protein 3 (515-523) is amino acids 199 to 207 fragment of Insulin-like growth factor-II mRNA binding protein 3. IGF2BP3 is an oncofetal RNA-binding protein that regulates targets such as insulin-like growth factor-2 (IGF-2) and ACTB (beta-actin). Synonyms: IGF2BP3 (515-523); IMP3 (515-523); KOC (515-523). | |
| Insulin-like Growth Factor-I Receptor human | ?95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| 2,3'-Dichloroacetophenone | 2,3'-Dichloroacetophenone is used as a reagent in the synthesis of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3 β (GSK-3 β). Also used as a reagent in the synthesis of benzimidazolyl pyridinones as insulin-like growth factor I (IGF-1R) kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 21886-56-6. Pack Sizes: 1g, 5g. Molecular Formula: C8H6Cl2O. US Biological Life Sciences. |  Worldwide |
| 293 Cell Lysate, Human Insulin Treated | Positive control (insulin treated 293 cells) for I7661-18M, Insulin-Like Growth Factor I Receptor, phosphorylated (Tyr1316). Group: Biologicals. Grades: Lysate. Pack Sizes: 200ul. US Biological Life Sciences. | Worldwide |
| 3-Benzyloxy-4-hydroxybenzaldehyde | A reactant used in the preparation of PDE4 and PDE7 inhibitors, insulin-like growth-factor-I receptor (IGF-IR) inhibitors and ferulic acid derivatives as xanthine oxidase inhibitors. Group: Biochemicals. Alternative Names: 4-Hydroxy-3-(phenylmethoxy)-benzaldehyde; 3-(Phenylmethoxy)-4-hydroxybenzaldehyde; 4-Hydroxy-3- (phenylmethoxy) benzaldehyde. Grades: Highly Purified. CAS No. 50773-56-3. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| AG 1024 - CAS 65678-07-1 | A cell-permeable, reversible, substrate competitive, and specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity. Group: Fluorescence/luminescence spectroscopy. | |
| AGL 2263 | AGL 2263 is an inhibitor of the insulin-like growth factor 1 receptor (IGF-1R; IC50 = 0.43 μM). Synonyms: (E)-2-(3,4-dihydroxybenzoyl)-3-(2-oxo-3H-1,3-benzoxazol-5-yl)prop-2-enenitrile. Grade: ≥98%. CAS No. 638213-98-6. Molecular formula: C17H10N2O5. Mole weight: 322.3. | |
| Aurintricarboxylic acid | Aurintricarboxylic acid acts as a histological dye and an insulin-like growth factor receptor 1 antagonist. Synonyms: 1,4-cyclohexadiene-1-carboxylic acid, 3-(bis(3-carboxy-4-hydroxyphenyl)methylen; aluminon free acid. Grade: 95%. CAS No. 4431-00-9. Molecular formula: C22H14O9. Mole weight: 422.34. | |
| AVJ16 | AVJ16 is a cancer cell migration inhibitor that targets the insulin-like growth factor 2 mRNA binding protein IGF2BP1 with a good affinity of Kd of 1.4?M. AVJ16 interferes with IGF2BP1 binding target mRNA to regulate gene expression and translation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2775241-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144873. |  |
| BMS-536924 | BMS-536924 is an orally active, competitive and selective insulin-like growth factor receptor (IGF-1R) kinase and insulin receptor (IR) inhibitor with IC 50 s of 100 nM and 73 nM, respectively. BMS-536924 has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 468740-43-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10262. | |
| BMS-536924 | BMS-536924 is a potent small molecule inhibitor of IGF-IR, which shows antitumor activity in multiple tumor models, including sarcoma. Synonyms: BMS536924; BMS 536924; Insulin-like Growth Factor-1 Receptor Inhibitor; (S)-4-((2-(3-chlorophenyl)-2-hydroxyethyl)amino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one. Grade: 98%. CAS No. 468740-43-4. Molecular formula: C25H26ClN5O3. Mole weight: 479.96. | |
| BMS695735 | BMS695735 is a benzimidazole inhibitor of the insulin-like growth factor-1 receptor. It was also found to have potent CYP3A4 inhibition. It has broad spectrum in vivo antitumor activity. Uses: Bms695735 has broad spectrum antitumor activity. Synonyms: BMS-695735; BMS 695735; BMS695735; CHEMBL459729; BDBM27888; DNC008930; 2(1H)-Pyridinone, 4-((2-(4-chloro-1H-pyrazol-1-yl)ethyl)amino)-3-(5-(1-(3-fluoropropyl)-4-piperidinyl)-7-methyl-1H-benzimidazol-2-yl)-; (3Z)-4-[2-(4-chloropyrazol-1-yl)ethylamino]-3-[6-[1-(3-fluoropropyl)piperidin-4-yl]-4-methyl-1,3-dihydrobenzimidazol-2-ylidene]pyridin-2-one. Grade: 95%. CAS No. 1054315-48-8. Molecular formula: C26H31ClFN7O. Mole weight: 512.02. | |
| BMS-754807 | BMS-754807 is an orally bioavailable antagonist of human insulin-like growth factor type I receptor (IGF-1R) with potential antineoplastic activity. BMS-7548077 binds to IGF-1R, preventing IGF-1 ligand binding and activation of IGF-1R-mediated signaling pathways. Synonyms: BMS754807; BMS-754807; BMS 754807. Grade: 0.98. CAS No. 1001350-96-4. Molecular formula: C23H24FN9O. Mole weight: 461.505. | |
| Chromeceptin | Chromeceptin is an IGF2 inhibitor. Chromeceptin inhibits Insulin-like growth factor 2 (IGF2) signaling by a process that begins with chromeceptin binding to multifunctional protein 2 (MFP-2). This interaction stimulates the expression of IGF binding protein 1 (IGFBP-1) and suppressor of cytokine signaling-3 (SOCS-3), both of which activate signal transducers and activators of transcription 6 (STAT6) to attenuate IGF signals. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Chromeceptin; 94G6. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 331859-86-0. Molecular formula: C19H16F3N3O. Mole weight: 359.35. Purity: >98%. IUPACName: 2-Amino-3-cyano-7-dimethylamino-4-(3-trifluoromethylphenyl)-4H-chromene. Canonical SMILES: FC(C1=CC(C2C(C#N)=C(N)OC3=C2C=CC(N(C)C)=C3)=CC=C1)(F)F. Product ID: ACM331859860. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Cimdelirsen | Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense molecule designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients. Synonyms: ISIS 766720; ISIS-766720; ISIS766720; IONIS-GHR-LRx; all-P-ambo-5'-O-(28-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-16,16-bis{[3-({6-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]hex-yl}amino)-3-oxopropoxy]methyl}-1-hydroxy-1,10,14,21-tetraoxo-2,18-dioxa-9,15,22-triaza-1λ5-phosphaoctacosan-1-yl)-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytidylyl-(3'→5')-2'-O-(2-methoxyethyl)-5-methyl-P-thiocytid. CAS No. 2131025-82-4. | |
| Figitumumab | Figitumumab (CP-751871) is a potent and fully human monoclonal anti - insulin-like growth factor 1 receptor ( IGF1R ) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC 50 of 1.8 nM [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CP-751871. CAS No. 943453-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99197. | |
| Figitumumab | Figitumumab is a monoclonal antibody that targets the insulin-like growth factor type I receptor (IGF1R). Figitumumab binds to IGF1R, resulting in a reduction in receptor expression on tumor cells that express IGF1R and inhibition of tumor growth. Synonyms: CP-751871. CAS No. 943453-46-1. | |
| Ganitumab | Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor ( IGF1R ). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity ( K D =0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 479; Human Anti-IGF1R Recombinant Antibody. CAS No. 905703-97-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99294. | |
| GSK1904529A | GSK1904529A is a potent, selective, orally active, and ATP-competitive inhibitor of insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) , with IC 50 s of 27 and 25 nM, respectively. GSK1904529A shows poor activity ( IC 50 >1 μM) in 45 other serine/threonine and tyrosine kinases. GSK1904529A exhibits anti-tumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1089283-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10524. | |
| HUMAN DES(1-6)IGF-II | HUMAN DES(1-6)IGF-II. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DES (1-6) IGF II;HUMAN DES(1-6)IGF-II;des (1-6) insulin-like growth factor ii;IGF-II (Δ 1-6);Insulin-like Growth Factor-II (Δ 1-6) human. Product Category: Heterocyclic Organic Compound. CAS No. 141909-47-9. Purity: 0.96. Product ID: ACM141909479. Alfa Chemistry ISO 9001:2015 Certified. | |
| IGF-1 LR3 | IGF-1 LR3 is a lengthened analogue of human insulin-like growth factor 1 (IGF-1). Synonyms: Long R3-IGF-1; IGF-1 Long R3; Long arginine 3-IGF-1. Grade: 95%. CAS No. 946870-92-4. Molecular formula: C400H625N111O115S9. Mole weight: 9117.6. | |
| IGF-1R inhibitor-2 | IGF-1R inhibitor-2 is an inhibitor of insulin-like growth factor-1 receptor (IGF-1R). Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis. Synonyms: 2-fluoro-6-((2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)benzamide. CAS No. 1116236-15-7. Molecular formula: C24H24FN7O2. Mole weight: 461.49. | |
| IGF-I 24-41 | IGF-I 24-41 is a 24-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (24-41); H-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH; L-tyrosyl-L-phenylalanyl-L-asparagyl-L-lysyl-L-prolyl-L-threonyl-glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine. Grade: ≥95%. CAS No. 135861-49-3. Molecular formula: C88H133N27O28. Mole weight: 2017.16. | |
| IGF-I (24-41) TFA | IGF-I (24-41) TFA is a 24-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (24-41) (TFA); IGF-I (24-41) Trifluoroacetate; H-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH.TFA; L-tyrosyl-L-phenylalanyl-L-asparagyl-L-lysyl-L-prolyl-L-threonyl-glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine Trifluoroacetate. Grade: >98%. Molecular formula: C88H133N27O28.C2HF3O2. Mole weight: 2131.18. | |
| IGF-I 30-41 | IGF-I 30-41 is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41); H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine. Grade: ≥95%. CAS No. 82177-09-1. Molecular formula: C51H83N19O19. Mole weight: 1266.32. | |
| IGF-I 30-41 acetate | IGF-I 30-41 acetate is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41) acetate; H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH.CH3CO2H; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine acetic acid. Grade: ≥95%. Molecular formula: C53H87N19O21. Mole weight: 1326.39. | |
| IGF-I (30-41) TFA | IGF-I (30-41) TFA is a 30-41 amino acid fragment of insulin-like growth factor I(IGF-I). IGF-I has anabolic, antioxidant, anti-inflammatory and cell-protective properties. Synonyms: Insulin-like Growth Factor I (30-41) (TFA); IGF-I (30-41) Trifluoroacetate; H-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-OH.TFA; glycyl-L-tyrosyl-glycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-L-threonine trifluoroacetate. Grade: >98%. Molecular formula: C51H83N19O19.C2HF3O2. Mole weight: 1380.36. | |
| I-OMe-Tyrphostin AG 538 | I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells. I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα) , with an IC 50 of 1 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: I-OMe-AG 538. CAS No. 1094048-77-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135680. | |
| Linsitinib | Linsitinib is a small-molecule dual insulin-like growth factor-1 receptor (IGF-IR) and insulin receptor (IR) kinase inhibitor. IGF-I receptor (IGF-IR) has been implicated in the promotion of tumorigenesis, metastasis and resistance to cancer therapies and thus Linsitinib may be a useful anticancer agent. Group: Biochemicals. Alternative Names: cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; OSI 906; OSI 906AA. Grades: Highly Purified. CAS No. 867160-71-2. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| LONG R3 IGF-1 (human) | LONG R3 IGF-1 (human) is a recombinant analog of human insulin-like growth factor-I (IGF-I). Synonyms: long R3 igf-I. CAS No. 143045-27-6. Molecular formula: C400H619N111O115S9. Mole weight: 9111.45. | |
| Mecasermin | Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Human IGF-I; FK 780. CAS No. 68562-41-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108905. | |
| MGF | Mechano growth factor (MGF) is a spliced variant of insulin-like growth factor 1 (IGF-1). IGF-1 is found in various tissues in the body including liver and muscle. Synonyms: MGF E-domain; IGF-1 EC; Mechano Growth Factor. Grade: 98%. Molecular formula: C121H199N40O40. Mole weight: 2868.19. | |
| Nordihydroguaiaretic acid | NDGA (Nordihydroguaiaretic acid), also known as masoprocol, is a naturally occurring antioxidant dicatechol originally derived from the creosote bush Larrea divaricatta with antipromoter, anti-inflammatory, and antineoplastic activities. NDGA directly inhibits activation of two receptor tyrosine kinases (RTKs), the insulin-like growth factor receptor (IGF-1R) and the c-erbB2/HER2/neu receptor, resulting in decreased proliferation of susceptible tumor cell populations. This agent may induce apoptosis in susceptible tumor cell populations as a result of disruption of the actin cytoskeleton in association with the activation of stress activated protein kinases (SAPKs). In addition, NDGA inhibits arachidonic acid 5-lipoxygenase (5LOX), resulting in diminished synthesis of inflammatory mediators such as prostaglandins and leukotrines; it may prevent leukocyte infiltration into tissues and the release of reactive oxygen species and, at higher concentrations, may also inhibit cyclooxygenase. Synonyms: 4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol. Grade: > 98 %. CAS No. 500-38-9. Molecular formula: C18H22O4. Mole weight: 302.36. | |
| Nordihydro Guaiaretic Acid-[d6] | Nordihydro Guaiaretic Acid-[d6], is the labelled analogue of Nordihydro Guaiaretic Acid. Nordihydroguaiaretic acid(NDGA), also known as masoprocol, is a naturally occurring antioxidant dicatechol originally derived from the creosote bush Larrea divaricatta with antipromoter, anti-inflammatory, and antineoplastic activities. NDGA directly inhibits activation of two receptor tyrosine kinases (RTKs), the insulin-like growth factor receptor (IGF-1R) and the c-erbB2/HER2/neu receptor, resulting in decreased proliferation of susceptible tumor cell populations. Synonyms: Nordihydro Guaiaretic Acid D6. CAS No. 1346600-58-5. Molecular formula: C18H16D6O4. Mole weight: 308.4. | |
| NVP-AEW541 | NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 ?M. NVP-AEW541 also inhibits InsR, IC50 with a value of 0.14 ?M. NVP-AEW541 has antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AEW541. CAS No. 475489-16-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50866. | |
| pappalysin-1 | A 400-kDa disulfide-linked dimer. Circulates in human pregnancy mainly as a complex with the proform of eosinophil major basic protein, which acts as an inhibitor of the peptidase. The rate of hydrolysis of IGFBP-4 is increased about 20-fold by the presence of insulin-like growth factor (IGF), whereas that of IGFBP-5 is decreased about two-fold. In peptidase family M43. Group: Enzymes. Synonyms: insulin-like growth factor binding protein-4 protease; pregnancy-associated plasma protein-A. Enzyme Commission Number: EC 3.4.24.79. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4363; pappalysin-1; EC 3.4.24.79; insulin-like growth factor binding protein-4 protease; pregnancy-associated plasma protein-A. Cat No: EXWM-4363. |  |
| PEG-MGF | PEG-MGF is a polyethylene glycol structure attached to a larger mechano growth factor molecule. It is a derived form of the IGF-1 (insulin-like growth factor-1), which stimulates myoblasts division and allows for muscle fibers to fuse and mature. Synonyms: Pegylated MGF, PEG IGF-1 Ec. Grade: >95%. Molecular formula: C121H200N42O39. Mole weight: 2948.15. | |
| PF-4708671 | PF-4708671 is a highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). PF-4708671 inhibits S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1), while having no effect on highly related RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated kinase) kinases. Group: Biochemicals. Alternative Names: 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole; PF 4708671. Grades: Highly Purified. CAS No. 1255517-76-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Picropodophyllin | Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM. Uses: Scientific research. Group: Natural products. Alternative Names: AXL1717; Picropodophyllotoxin; PPP. CAS No. 477-47-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15494. | |
| Recombinant IGF-I (human) | Recombinant IGF-I (human) is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR) and inhibits its activity. Synonyms: Recombinant human insulin-like growth factor-1; Human IGF-I; Insulin-like Growth Factor-I (E3R) human; rec IGF-I (human). Grade: ≥95% by SDS-PAGE. CAS No. 67763-96-6. | |
| Robatumumab | Robatumumab (Sch 717454) is an anti-human IGF-1R ( insulin-like growth factor receptor-1 ) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Sch 717454; 19D12. CAS No. 934235-44-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99218. | |
| S961 acetate | S961 acetate is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1]. Uses: Scientific research. Group: Peptides. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2093B. | |
| Sorbic acid | Sorbic acid is an effective, safe, and non-toxic food preservative. It can effectively inhibit most molds, yeasts, and certain bacteria. Sorbic acid is orally active and can enhance the growth performance of economically important animals (Duroc × Landrace × Yorkshire piglets) by activating the insulin-like growth factor system ( IGF ), and it can also lead to lipid accumulation by disrupting lipid clearance pathways [1] [2] [3] [4] ?. Uses: Scientific research. Group: Natural products. CAS No. 110-44-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0626. | |
| Veligrotug | Veligrotug is an IgG1-kappa, anti- IGF1R (insulin-like growth factor 1 receptor, CD221) chimeric monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2728655-31-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990084. | |
| Voglibose | Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis [1]. Uses: Scientific research. Group: Natural products. CAS No. 83480-29-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0025. | |
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