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| Product | Description | |
|---|---|---|
| HIV-1 integrase inhibitor | HIV-1 integrase inhibitor is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 544467-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13025. |  |
| HIV-1 integrase inhibitor | HIV-1 integrase inhibitor is uesful for anti-HIV, which can target HIV-1 integrase and depress the activity in the treatment of HIV infection, AIDS, and other similar diseases characterized by integration of a retroviral genome into a host chromosome. Synonyms: (Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid. Grades: >98%. CAS No. 544467-07-4. Molecular formula: C11H9N3O4. Mole weight: 247.21. |  |
| HIV-1 integrase inhibitor 2 | HIV-1 integrase inhibitor 2 is useful for anti-HIV, which can target HIV-1 integrase and depress the activity in the treatment of HIV infection, AIDS, and other similar diseases characterized by integration of a retroviral genome into a host chromosome. It did not affect integrase-DNA binding and only weakly inhibited the catalytic activities of integrase. Synonyms: CX04328; CX-04328; CX 04328; 3-Quinolineacetic acid, 6-chloro-2-methyl-4-phenyl-a-propyl-. Grades: >98%. CAS No. 957890-42-5. Molecular formula: C21H20ClNO2. Mole weight: 353.84. | |
| 10-Hydroxy Cabotegravir | 10-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H17F2N3O6, Molecular Weight: 421.35. US Biological Life Sciences. |  Worldwide |
| 10-Hydroxy Cabotegravir-d3 | 10-Hydroxy Cabotegravir-d3 is the labelled form of 10-Hydroxy Cabotegravir. 10-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H14D3F2N3O6, Molecular Weight: 424.37. US Biological Life Sciences. | Worldwide |
| 1-(2,2-Dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester | 1-(2,2-Dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester is an intermediate used in the synthesis of Defluoro Dolutegravir (D228715), which is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Group: Biochemicals. Grades: Highly Purified. CAS No. 1246616-75-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H21NO7, Molecular Weight: 327.33. US Biological Life Sciences. | Worldwide |
| 1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic Acid | 1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic Acid is an intermediate in the synthesis of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206102-06-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H17NO6. US Biological Life Sciences. | Worldwide |
| 1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic Acid Methyl Ester | 1-(2,3-Dihydroxypropyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic Acid Methyl Ester is an intermediate in the synthesis of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206102-07-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C17H19NO6, Molecular Weight: 333.34. US Biological Life Sciences. | Worldwide |
| 13-Hydroxy Cabotegravir | 13-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H17F2N3O6, Molecular Weight: 421.35. US Biological Life Sciences. | Worldwide |
| 13-Hydroxy Cabotegravir-d3 | 13-Hydroxy Cabotegravir-d3 is the labelled form of 13-Hydroxy Cabotegravir. 13-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H14D3F2N3O6, Molecular Weight: 424.37. US Biological Life Sciences. | Worldwide |
| 1,3-Oxazinan-2-one | 1,3-Oxazinan-2-one is a reactant used in the preparation of HIV integrase inhibitors active against raltegravir resistant strains. Group: Biochemicals. Grades: Highly Purified. CAS No. 5259-97-2. Pack Sizes: 500mg, 5g. Molecular Formula: C4H7NO2, Molecular Weight: 101.1. US Biological Life Sciences. | Worldwide |
| 1, 6-Dihydro-5-hydroxy-1-methyl-2- [1-methyl-1- [ [benzylcarbamoyl] amino] ethyl] -6-oxo-4-pyrimidinecarboxylic Acid Methyl Ester | An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 888504-27-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 1, 6-Dihydro-5-hydroxy-1-methyl-2- [1-methyl-1- [ [benzylcarbamoyl] amino] ethyl] -6-oxo-4-pyrimidinecarboxylic Acid Methyl Ester-d3 | A labeled intermediate in the preparation of labeled HIV-integrase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 1, 6-Dihydro-5-hydroxy-2- [1-methyl-1- [ [benzylcarbamoyl] amino] ethyl] -6-oxo-4-pyrimidinecarboxylic Acid | An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 519032-08-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1-Benzyl-3-bromobenzene | 1-Benzyl-3-bromobenzene is used in the synthesis of inhibitors of HIV-1 integrase. It is also used to prepare C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2. Group: Biochemicals. Grades: Highly Purified. CAS No. 27798-39-6. Pack Sizes: 250mg, 2.5g. Molecular Formula: C13H11Br. US Biological Life Sciences. | Worldwide |
| 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide | 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (compound 8) is an HIV-1 integrase inhibitor that effectively inhibits both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration reaction. 1-Butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide can be utilized in HIV-1 research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMIM-TFSI; BMI-TFSI. CAS No. 174899-83-3. Pack Sizes: 1 mg. Product ID: HY-W010937. | |
| 2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide | An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: 2-(1-Amino-1-methylethyl)-N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-. Grades: Highly Purified. CAS No. 518048-03-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide-d3 | An labeled intermediate in the preparation of labeled HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: 2-(1-Amino-1-methylethyl)-N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-(methyl-d3)-6-oxo-4-pyrimidinecarboxamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-[(1E)-2-Phenylethenyl]-3-(phenylmethoxy)-4H-pyran-4-one | 2-[(1E)-2-Phenylethenyl]-3-(phenylmethoxy)-4H-pyran-4-one is an intermediate in the synthesis of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206102-05-7. Pack Sizes: 25mg, 100mg. Molecular Formula: C20H16O3. US Biological Life Sciences. | Worldwide |
| 21-Hydroxy Cabotegravir | 21-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H17F2N3O6, Molecular Weight: 421.35. US Biological Life Sciences. | Worldwide |
| 21-Hydroxy Cabotegravir-d3 | 21-Hydroxy Cabotegravir-d3 is the labelled form of 21-Hydroxy Cabotegravir. 21-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H14D3F2N3O6, Molecular Weight: 424.37. US Biological Life Sciences. | Worldwide |
| 24-Hydroxy Cabotegravir | 24-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C19H17F2N3O6, Molecular Weight: 421.35. US Biological Life Sciences. | Worldwide |
| 24-Hydroxy Cabotegravir-d3 | 24-Hydroxy Cabotegravir-d3 is the labelled form of 24-Hydroxy Cabotegravir. 24-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H14D3F2N3O6, Molecular Weight: 424.37. US Biological Life Sciences. | Worldwide |
| 26-Hydroxy Cabotegravir | 26-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C19H17F2N3O6, Molecular Weight: 421.35. US Biological Life Sciences. | Worldwide |
| 26-Hydroxy Cabotegravir-d3 | 26-Hydroxy Cabotegravir-d3 is the labelled form of 26-Hydroxy Cabotegravir. 26-Hydroxy Cabotegravir is a metabolite of Cabotegravir (C050100). Cabotegravir is a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C19H14D3F2N3O6, Molecular Weight: 424.37. US Biological Life Sciences. | Worldwide |
| 2-Bromophenanthridone | 2-Bromophenanthridone is a 2-bromo substituted derivative of phenathridinone that exhibits aryl hydrocarbon (Ah) receptor antagonist activity. It is also used in the preparation of potential HIV-1 integrase inhibitors. Group: Biochemicals. Alternative Names: 2-Bromo-6(5H)-phenanthridinone; NSC 112910; SG 00589. Grades: Highly Purified. CAS No. 27353-48-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Chloro-3-fluoro Elvitegravir | 2-Chloro-3-fluoro Elvitegravir is an impurity of Elvitegravir (E509000), which is a novel inhibitor of human immunodeficiency virus type 1 integrase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C23H23ClFNO5, Molecular Weight: 447.88. US Biological Life Sciences. | Worldwide |
| 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir | 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir is an impurity of a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1391918-17-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C20H23FN6O6. US Biological Life Sciences. | Worldwide |
| 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-Amino-2-oxoacetic Acid) Raltegravir | 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-Amino-2-oxoacetic Acid) Raltegravir is a derivative of Raltegravir (R100300), a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1064706-98-4. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C18H19FN4O6. US Biological Life Sciences. | Worldwide |
| 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) (E)-2-(N,N-Dimethylformimidamide) Raltegravir | 2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) (E)-2-(N,N-Dimethylformimidamide) Raltegravir is an impurity of Raltegravir (R100300), a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1193687-85-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C19H24FN5O3. US Biological Life Sciences. | Worldwide |
| 2-Fluoro-6-hydroxyphenylboronic Acid | 2-Fluoro-6-hydroxyphenylboronic Acid is a synthetic reagent used in the preparation of alkylene-bridged [(3,4-dihydro-2H-benzo[b][1,4]oxazinyl) or (piperidinyl)(biphenyl-3-yl)pyrazolo[1,5-a]pyrimidinyl](tert-butoxy)acetic acid derivatives as HIV integrase inhibitors for treating HIV infection. Group: Biochemicals. Grades: Highly Purified. CAS No. 1256345-60-4. Pack Sizes: 250mg, 1g. Molecular Formula: C6H6BFO3. US Biological Life Sciences. | Worldwide |
| 2-Hydroxyisoquinoline-1,3(2H,4H)-dione | 2-Hydroxyisoquinoline-1,3(2H,4H)-dione was recently discovered as a scaffold for the inhibition of HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase. It was investigated its interaction with Mg2+ and Mn2+ using different spectroscopic techniques and report that 2-hydroxyisoquinoline-1,3(2H,4H)-dione forms a 1:1 complex with Mg2+ but a 1:2 complex with Mn2+. Antiviral agent. Group: Biochemicals. Alternative Names: 2-Hydroxy-1,3(2H,4H)-isoquinolinedione. Grades: Highly Purified. CAS No. 6890-08-0. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Methyltetrahydro-2-furancarbonitrile | 2-Methyltetrahydro-2-furancarbonitrile is used as a reagent for the synthesis of C2-carbon-linked heterocyclic-5-hydroxy-6-oxo-dihydropyrimidine-4-carboxamides as HIV-1 integrase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 19679-75-5. Pack Sizes: 100mg, 500mg. Molecular Formula: C6H9NO, Molecular Weight: 111.14. US Biological Life Sciences. | Worldwide |
| (2S) -4-Oxo-1, 2-pyrrolidinedicarboxyl ic Acid 1-Benzyl 2-Methyl Ester | Used in the preparation of dipeptidyl peptidase IV inhibitors and (hydroxy) (carbamoyl) pyrimidinones as potent and orally bioavailable HIV integrase inhibitors. Group: Biochemicals. Alternative Names: (S)-1-Benzyloxycarbonyl-4-oxoproline Methyl Ester. Grades: Highly Purified. CAS No. 16217-15-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 3'-Aminoacetophenone | 3'-Aminoacetophenone has potential anti-bacterial properties in addition to being used in the synthesis of selective antagonists at human A2B adenosine receptors. As well, it is used in the synthesis of HIV-1 Integrase Inhibitors. Group: Biochemicals. Alternative Names: 1-(3-Aminophenyl)ethan-1-one; 1-(3-Aminophenyl)ethanone; 1-Acetyl-3-aminobenzene; 3-Acetylaniline; 3-Acetylphenylamine; 3-Methylcarbonylaniline; 3'-Aminoacetophenone; NSC 7637; m-Acetylaniline; m-Aminoacetophenone; m-Aminoacetylbenzene; β-Aminoacetophenone. Grades: Highly Purified. CAS No. 99-03-6. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| 3-Aminomethyl-3-[bis (phenylmethyl) amino]oxetane | 3-Aminomethyl-3-[bis (phenylmethyl) amino]oxetane is used as a reactant in the preparation of spiropyrido[1,2-a]pyrazine compounds useful as HIV integrase inhibitors for treatment or prevention of HIV infection and AIDS. Group: Biochemicals. Grades: Highly Purified. CAS No. 1021392-84-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C18H22N2O, Molecular Weight: 282.38. US Biological Life Sciences. | Worldwide |
| 3-Benzyloxy-2-(2-hydroxy-2-phenylethyl)-4H-pyran-4-one | 3-Benzyloxy-2-(2-hydroxy-2-phenylethyl)-4H-pyran-4-one is an intermediate in the synthesis of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1206102-04-6. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H18O4. US Biological Life Sciences. | Worldwide |
| 3-Bromo-1-(2,2-dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester | 3-Bromo-1-(2,2-dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester is an intermediate in the synthesis of Defluoro Dolutegravir (D228715). Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Group: Biochemicals. Grades: Highly Purified. CAS No. 1246616-76-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C15H20BrNO7, Molecular Weight: 406.23. US Biological Life Sciences. | Worldwide |
| 3-Bromo-1,4-dihydro-4-oxo-1-(2-oxoethyl)-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester | 3-Bromo-1,4-dihydro-4-oxo-1-(2-oxoethyl)-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester is an intermediate in the synthesis of Defluoro Dolutegravir (D228715). Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Group: Biochemicals. Grades: Highly Purified. CAS No. 1246616-77-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C13H14BrNO6, Molecular Weight: 360.16. US Biological Life Sciences. | Worldwide |
| 4-Defluoro Raltegravir | An impurity of Raltegravir. Raltegravir is an integrase inhibitor as an antiretroviral drug. It can be used for the treatment of HIV infection. Synonyms: 1,6-Dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-N-(phenylmethyl)-4-pyrimidinecarboxamide. Grades: > 95%. CAS No. 1193687-87-4. Molecular formula: C20H22N6O5. Mole weight: 426.44. | |
| 4-Hydroxy Coumarin | 4-Hydroxy Coumarin is a plant derived antioxidant, protecting against lipid peroxidation, as well as a potential inhibitor of HIV-1 Integrase. Group: Biochemicals. Alternative Names: 4-Hydroxy-2H-1-benzopyran-2-one; 4-Coumarinol; 4-Hydroxy-2H-1-benzopyran-2-one; 4-Hydroxy-2H-benzo[b]pyran-2-one; 4-Hydroxy-2H-chromen-2-one; 4-Hydroxychromen-2-one; 4-Hydroxycoumariin; 4-Hydroxycoumarin; Benzotetronic Acid; NSC 11889. Grades: Highly Purified. CAS No. 1076-38-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 4-Oxo-1,4-dihydroquinoline Carboxylic Acid | 4-Oxo-1,4-dihydroquinoline Carboxylic Acid is a novel HIV-1 integrase strand transfer inhibitor. Group: Biochemicals. Alternative Names: 1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid; 4-Quinolone-3-carboxylic Acid. Grades: Highly Purified. CAS No. 13721-01-2. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 5,6-Dihydroxyindole-2-carboxylic Acid | 5,6-Dihydroxyindole-2-carboxylic Acid is the indole analogue of DOPA. 5,6-Dihydroxyindole-2-carboxylic Acid is a precursor to melanin as well as potential as HIV-1 integrase inhibitors. Group: Biochemicals. Alternative Names: 2-Carboxy-5,6-dihydroxyindole; 5,6-Dihydroxy-1H-indole-2-carboxylic Acid; 5,6-Dihydroxy-2-carboxyindole. Grades: Highly Purified. CAS No. 4790-8-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 5-Methyl-1,3,4-oxadiazole-2-carboxylic Acid, Potassium Salt | An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: Oxadiazole Potassim Salt. Grades: Highly Purified. CAS No. 888504-28-7. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Altenusin | Altenusin is a a biphenyl derivative with an IC50 value of 4.3±0.3 μM in the TR assay, which is isolated from the endophytic fungus Alternaria. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human P301L mutant tau when used at a concentration of 10 μM. Altenusin is known to have antioxidant properties and to inhibit several enzymes, including myosin light chain kinase, sphingomyelinase, acetylcholinesterase, cFMS kinase, pp60c-SRc kinase and HIV-1 integrase. Synonyms: Alutenusin; MS 341; MS-341; MS341. Grades: ≥98%. CAS No. 31186-12-6. Molecular formula: C15H14O6. Mole weight: 290.27. | |
| Altenusin, Penicillium sp. | Sphingomyelinase (N-SMase) and strong pp60c-Src inhibitor. Inhibits cFMS receptor tyrosine kinase (CSF-1/m-CSF receptor tyrosine kinase) which is implicated in cancer and bone diseases. Myosin light chain kinase inhibitor. Also exhibits anti-HIV-1 integrase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 31186-12-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Benzyl [1-[4-[[ (4-Fluorobenzyl) amino]carbonyl]-5-hydroxy-1-methyl-6-oxo-. 1,6-dihydropyrimidin-2-yl]-1-methylethyl]carbamate. | An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: N-[1-[4-[[[ (4-Fluorophenyl) methyl]amino]carbonyl]-1, 6-dihydro-5-hydroxy-1-methyl-6-oxo-2-pyrimidinyl]-1-methylethyl]-carbamic Acid Phenylmethyl Ester. Grades: Highly Purified. CAS No. 518048-02-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Benzyl [1-[4-[[ (4-Fluorobenzyl) amino]carbonyl]-5-hydroxy-1-methyl-6-oxo-. 1,6-dihydropyrimidin-2-yl]-1-methylethyl]carbamate-d3. | A labeled intermediate in the preparation of labeled HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: N-[1-[4-[[[ (4-Fluorophenyl) methyl]amino]carbonyl]-1, 6-dihydro-5-hydroxy-1- (methyl-d3) -6-oxo-2-pyrimidinyl]-1-methylethyl]carbamic Acid Phenylmethyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Benzyl [1-Cyano-1-methylethyl]carbamate. | An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: N-(1-Cyano-1-methylethyl)carbamic Acid Phenylmethyl Ester; (1-Cyano-1-methylethyl)carbamic Acid Benzyl Ester. Grades: Highly Purified. CAS No. 100134-82-5. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Benzyl [2-Amino-2- (hydroxyimino) -1, 1-dimethylethyl] carbamate | An intermediate in the preparation of HIV-integrase inhibitors. Group: Biochemicals. Alternative Names: N-[2-(Hydroxyamino)-2-imino-1,1-dimethylethyl]-carbamic Acid Benzyl Ester; N-[2-(Hydroxyamino)-2-imino-1,1-dimethylethyl]-carbamic Acid Phenylmethyl Ester. Grades: Highly Purified. CAS No. 518047-98-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| BI 224436 | BI 224436 is a novel HIV-1 non-catalytic-site integrase inhibitor; has antiviral EC50s of <15 nM against different HIV-1 laboratory strains and cellular cytotoxicity of>90 μM. Synonyms: BI-224436; BI 224436; BI224436. Grades: >98%. CAS No. 1155419-89-8. Molecular formula: C27H26N2O4. Mole weight: 442.51. | |
| BI 224436 | BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC 50 values of less than 15 nM against different HIV-1 laboratory strains. Uses: Scientific research. Group: Signaling pathways. CAS No. 1155419-89-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18595. | |
| Bictegravir | Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC 50 of 7.5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883. CAS No. 1611493-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605. | |
| Bictegravir | Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM for strand transfer activity. Bictegravir is a drug of the integrase inhibitor class that was copied from Dolutegravir by scientists at Gilead Sciences. Bictegravir also inhibits HIV-1 viral infection in MT-2 and MT-4 cells, CD4+ T cells, and macrophages (EC50s = 1.5, 2.5, 1.5, and 6.6 nM, respectively) without exhibiting cytotoxicity (CC50s = 10.3, 3.7, 13, and 29.8 μM, respectively). In 2016, bictegravir was in a Phase 3 trial as part of a single tablet regimen in combination with tenofovir alafenamide (TAF) and emtricitabine (FTC) for the treatment of HIV-1 infection. Synonyms: GS-9883; GS 9883; GS9883. Grades: ≥98%. CAS No. 1611493-60-7. Molecular formula: C21H18F3N3O5. Mole weight: 449.39. | |
| Bictegravir sodium | Bictegravir sodium is a HIV-1 integrase strand transfer inhibitor that is derived from the drug dolutegravir. Synonyms: Bictegravir sodium|1807988-02-8|Bictegravir (sodium)|UNII-4L5MP1Y7W7|4L5MP1Y7W7|sodium;(1S, 11R, 13R)-3, 6-dioxo-7-[(2, 4, 6-trifluorophenyl)methylcarbamoyl]-12-oxa-2, 9-diazatetracyclo[11.2.1.02, 11.04, 9]hexadeca-4, 7-dien-5-olate|Bictegravir sodium [USAN]|Bictegravir sodium (JAN / USAN) |CHEMBL3989867|SCHEMBL 19991461|CHEBI: 172961|BCP20910|HY-17605A|AC-30681|CS-0380750|D10910|N16970|A904622|Q27259 952|GS-9883; GS 9883; GS9883; GS-9883-01; GS9883-01; GS 9883-01|(2R,5S,13aR)-8-Hydroxy-7,9-dioxo-N-((2,4,6-trifluorophenyl)methyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido(1',2':4,5)pyrazino(2,1-b)(1,3)oxazepine-10-carboxamide monosodium salt|2,5-Methanopyrido(1',2':4,5)pyrazino(2,1-b)(1,3)oxazepine-10-carboxamide, 2,3,4,5,7,9,13,13a-octahydro-8-hydroxy-7,9-dioxo-N-((2,4,6-trifluorophenyl)methyl)-, sodium salt (1:1), (2R,5S,13aR)-|Sodium (2R,5S,13aR)-7,9-dioxo-10-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1, 3]oxazepin-8-olate|sodium (2R,5S,13aR)-7,9-dioxo-10-[(2,4,6-trifluorobenzyl)carbamoyl]-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepin-8-olate. Grades: >98%. CAS No. 1807988-02-8. Molecular formula: C21H17F3N3NaO5. Mole weight: 471.4. | |
| Bictegravir sodium | Bictegravir sodium is a potent inhibitor of HIV-1 integrase , with an IC 50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883 sodium. CAS No. 1807988-02-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605A. | |
| BMS-538203 | BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent. Synonyms: BMS-538203; BMS 538203; BMS538203. Grades: >98%. CAS No. 543730-41-2. Molecular formula: C12H12FNO5. Mole weight: 269.23. | |
| BMS-707035 | BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Uses: Hiv integrase inhibitors. Synonyms: BMS-707035; BMS-707035; BMS-707035. Grades: >98%. CAS No. 729607-74-3. Molecular formula: C17H19FN4O5S. Mole weight: 410.42. | |
| Cabotegravir | Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 ( OAT1 / OAT3 ) inhibitor with IC 50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIV ADA , OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1265744; S/GSK1265744. CAS No. 1051375-10-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15592. | |
| Cabotegravir (GSK744, GSK1265744) | Cabotegravir (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor against a broad range of HIV subtypes, and inhibits the HIV-1 integrase catalyzed strand transfer reaction with IC50 of 3.0 nM. Phase 2. Uses: Hiv integrase inhibitors. Synonyms: S/GSK1265744; S/GSK 1265744; S/GSK-1265744; GSK744; GSK-744; GSK 744; Cabotegravir. Grades: >98%. CAS No. 1051375-10-0. Molecular formula: C19H17F2N3O5. Mole weight: 405.35. | |
| Cabotegravir sodium | Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 ( OAT1 / OAT3 ) inhibitor with IC 50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIV ADA , OAT3 and OAT1, respectively. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir sodium can be used to research AIDS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1265744 sodium; S/GSK1265744 sodium. CAS No. 1051375-13-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15592A. | |
| D-Alaninol | A reagent used in the synthesis of naphthyridinone integrase inhibitors. Synonyms: (R)-(-)-2-Amino-1-propanol; (2R)-2-aminopropan-1-ol. Grades: > 95 % by HPLC. CAS No. 35320-23-1. Molecular formula: C3H9NO. Mole weight: 75.10. | |
| DL-Alaninol Methyl Ether | Used in the preparation of heterocyclic compounds, as integrase inhibiting antiviral agents. Group: Biochemicals. Alternative Names: (±)-1-Methoxy-2-propanamine; (±)-1-Methoxy-2-propylamine; 1-Methoxy-2-aminopropane; 1-Methoxy-2-propanamine; 1-Methoxy-2-propylamine; 1-Methoxyisopropylamine; 1-Methyl-2-methoxyethylamine; 2-Amino-1-methoxypropane; 2-Methoxy-1-methylethylamine; 2-Methoxyisopropylamine; DL-Alaninol methyl ether; Methoxyisopropylamine; [1-(Methoxy)propan-2-yl]amine. Grades: Highly Purified. CAS No. 37143-54-7. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| D,L-Serine, Methyl Ester, Hydrochloride | D,L-Serine Methyl Ester Hydrochloride is used as a reactant in the preparation of chicoric acid analogs as HIV-1 integrase inhibitors. Also used in the total synthesis of (-)-Hennoxazole A. Group: Biochemicals. Grades: Highly Purified. CAS No. 5619-4-5. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C?H?NO? HCl. US Biological Life Sciences. | Worldwide |
| D-Lysine,n2-acetyl- | D-Lysine,n2-acetyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Na-Acetyl-D-lysine;, Ac-D-Lys-OH, Integrase inhibitor, R3{2}, CTK8F7492, AKOS006272968, AG-G-08509, 58840-79-2. Product Category: Heterocyclic Organic Compound. CAS No. 58840-79-2. Molecular formula: C8H16N2O3. Mole weight: 188.22. Purity: 0.96. IUPACName: (2R)-2-acetamido-6-aminohexanoic acid. Product ID: ACM58840792. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Dolutegravir | Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Group: Biochemicals. Alternative Names: (4R, 12aS)-N-[(2, 4-Difluorophenyl)methyl]-3, 4, 6, 8, 12, 12a-hexahydro-7-hydroxy-4-methyl-6, 8-dioxo-2H-pyrido[1', 2':4, 5]pyrazino[2, 1-b][1, 3]oxazine-9-carboxamide; GSK 1349572; S/GSK1349572. Grades: Highly Purified. CAS No. 1051375-16-6. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C20H19F2N3O5, Molecular Weight: 419.38. US Biological Life Sciences. | Worldwide |
| Dolutegravir | Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC 50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC 50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC 50 =3.6-5.8 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S/GSK1349572. CAS No. 1051375-16-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13238. | |
| Dolutegravir (GSK1349572) | Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). Synonyms: GSK-1349572; GSK 1349572; GSK1349572; Tivicay. Grades: ≥98%. CAS No. 1051375-16-6. Molecular formula: C20H19F2N3O5. Mole weight: 419.38. | |
| Dolutegravir sodium | Dolutegravir sodium salt is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. Uses: Hiv integrase inhibitors. Synonyms: DTG; GSK1349572; GSK 1349572; GSK-1349572. Grades: >98%. CAS No. 1051375-19-9. Molecular formula: C20H18F2N3NaO5. Mole weight: 441.36. | |
| Dolutegravir sodium | Dolutegravir sodium (S/GSK1349572 sodium) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC 50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir sodium (S/GSK1349572 sodium) inhibits HIV-1 viral replication with an IC 50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir sodium (S/GSK1349572 sodium) retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC 50 =3.6-5.8 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S/GSK1349572 sodium. CAS No. 1051375-19-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13238A. | |
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