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| Product | Description | |
|---|---|---|
| Irinotecan Impurity 17 | Irinotecan Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1332610-75-9. Molecular formula: C19H14N2O4. Mole weight: 334.33. Catalog: APB1332610759. |  |
| Irinotecan Impurity 18 | Irinotecan Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1255644-71-3. Molecular formula: C33H38N4O6. Mole weight: 586.69. Catalog: APB1255644713. | |
| Irinotecan Impurity 25 | Irinotecan Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1026078-50-1. Molecular formula: C11H20N2O2. Mole weight: 212.29. Catalog: APB1026078501. | |
| Irinotecan Impurity 33 | Irinotecan Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 14154-82-6. Molecular formula: C13H26Cl2N2O2. Mole weight: 313.26. Catalog: APB14154826. | |
| Irinotecan Impurity 35 (Sodium Salt) | Irinotecan Impurity 35 (Sodium Salt). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1329502-92-2. Molecular formula: C33H39N4NaO7. Mole weight: 626.69. Catalog: APB1329502922. | |
| Irinotecan Impurity 9 | Irinotecan Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124622-81-7. Molecular formula: C24H24N2O4. Mole weight: 404.47. Catalog: APB124622817. | |
| Irinotecan Impurity M | Irinotecan Impurity M. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4S)-4,11-diethyl-4,12-dihydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate. CAS No. 185336-12-3. Molecular formula: C33H38N4O7. Mole weight: 602.68. Catalog: APB185336123. | |
| Irinotecan EP Impurity A | Irinotecan EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate. CAS No. 103816-16-6. Molecular formula: C31H34N4O6. Mole weight: 558.62. Catalog: APB103816166. | |
| Irinotecan EP Impurity E (SN-38) | An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. It inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. Uses: The treatment of colorectal cancer. Synonyms: (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione; 10-Hydroxy-7-ethylcamptothecin; SN 38 Lactone; Irinotecan EP Impurity E; SN-38; USP Irinotecan Related Compound B; Irinotecan Related Compound B; Irinotecan EP Impurity E; NSC-673596. Grade: ≥95%. CAS No. 86639-52-3. Molecular formula: C22H20N2O5. Mole weight: 392.40. |  |
| 11-Desethyl Irinotecan | 11-Desethyl Irinotecan is an impurity of the DNA topoisomerase inhibitor Irinotecan (I767500). Group: Biochemicals. Alternative Names: (4S)-4-Ethyl-3, 4, 12, 14-tetrahydro-4-hydroxy-3, 14-dioxo-1H-pyrano[3', 4':6, 7]indolizino[1, 2-b]quinolin-9-yl Ester [1,4'-Bipiperidine]-1'-carboxylic Acid; 1H-Pyrano[3', 4':6, 7]indolizino[1, 2-b]quinoline, [1,4'-Bipiperidine]-1'-carboxylic Acid deriv.; 10- [4- (1-Piperidino) -1-piperidinocarbonyloxy] camptothecin. Grades: Highly Purified. CAS No. 103816-16-6. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| 7-Ethyl Camptothecin | The main reasons for the superior antitumor activity of 7-Ethylcamptothecin compared with CPT are as follows: (a) 7-Ethylcamptothecin had a stronger growth-inhibiting activity against tumor cells, and (b) 7-Ethylcamptothecin remained in the intestinal tract for a longer time and in higher amounts when administered in vivo. 7-Ethyl Camptothecin is a natural compound found in the barks of Camptotheca acuminata Decne, it can be used as a cosmetics material. Synonyms: (S)-4,11-Diethyl-4-hydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione; 7-ethylcamptothecin; (4S)-4,11-diethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; Irinotecan EP Impurity F. Grade: >98%. CAS No. 78287-27-1. Molecular formula: C22H20N2O4. Mole weight: 376.42. | |
| 9-methoxy-7-ethylcamptothecin | 9-methoxy-7-ethylcamptothecin is an impurity of irinotecan and camptothecin analogues. It is also an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: (S)-4,11-Diethyl-4-hydroxy-10-methoxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione; Camptothecin Impurity 17. CAS No. 200619-39-2. Molecular formula: C23H22N2O5. Mole weight: 406.43. | |
| Camptothecin | Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231. Camptothecin is extratced from the barks of Camptotheca acuminata Decne. It can be used in cosmetics material. It is also an impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Uses: Adcs cytotoxin. Synonyms: camptothecin; 7689-03-4; Camptothecine; (S)-(+)-Camptothecin; Campathecin; (+)-Camptothecin; (+)-Camptothecine; d-Camptothecin; 20(S)-Camptothecine; 21,22-Secocamptothecin-21-oic acid lactone; NSC94600; Camptothecine (S,+); CHEMBL65; (S)-4-ethyl-4-hydroxy-1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-94600; (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinol. Grade: >98%. CAS No. 7689-3-4. Molecular formula: C6H14N2O2.ClH. Mole weight: 182.65. | |
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