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The isomer of isocitrate involved is (1R,2S)-1-hydroxypropane-1,2,3-tricarboxylate. Group: Enzymes. Synonyms: isocitrase; isocitritase; isocitratase; threo-Ds-isocitrate glyoxylate-lyase; isocitrate glyoxylate-lyase. Enzyme Commission Number: EC 4.1.3.1. CAS No. 9045-78-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4898; isocitrate lyase; EC 4.1.3.1; 9045-78-7; isocitrase; isocitritase; isocitratase; threo-Ds-isocitrate glyoxylate-lyase; isocitrate glyoxylate-lyase. Cat No: EXWM-4898.
methylisocitrate lyase
The enzyme acts on threo-Ds-2-methylisocitrate, but not on threo-Ds-isocitrate, threo-DL-isocitrate or erythro-Ls-isocitrate. Group: Enzymes. Synonyms: 2-methylisocitrate lyase; MICL; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase. Enzyme Commission Number: EC 4.1.3.30. CAS No. 57827-77-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4909; methylisocitrate lyase; EC 4.1.3.30; 57827-77-7; 2-methylisocitrate lyase; MICL; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate pyruvate-lyase. Cat No: EXWM-4909.
2-Bromopropanedioic Acid
2-Bromopropanedioic Acid is an analog of the competitive inhibitor, malonate. Inhibitory activity towards Isocitrate lyase. Group: Biochemicals. Alternative Names: Bromomalonic Acid; Monobromomalonic Acid. Grades: Highly Purified. CAS No. 600-31-7. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
2-methylisocitrate dehydratase
The enzyme from the fungus Yarrowia lipolytica (Saccharomycopsis) does not act on isocitrate. Group: Enzymes. Synonyms: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase. Enzyme Commission Number: EC 4.2.1.99. CAS No. 170780-51-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5083; 2-methylisocitrate dehydratase; EC 4.2.1.99; 170780-51-5; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase. Cat No: EXWM-5083.
aconitate hydratase
Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate. The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate. cis-Aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3-tricarboxylate. An iron-sulfur protein, containing a [4Fe-4S] cluster to which the substrate binds. Group: Enzymes. Synonyms: cis-aconitase; aconitase; AcnB; 2-methylaconitate hydratase; citrate(isocitrate) hydro-lyase. Enzyme Commission Number: EC 4.2.1.3. CAS No. 9024-25-3. Aconitase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5020; aconitate hydratase; EC 4.2.1.3; 9024-25-3; cis-aconitase; aconitase; AcnB; 2-methylaconitate hydratase; citrate(isocitrate) hydro-lyase. Cat No: EXWM-5020.
Inhibitor of isocitrate lyase, the key enzyme of the glyoxylate cycle, essential for bacterial growth. Antimicrobial. Antibacterial. Inhibits the growth of bacteria expressing isocitrate lyase. Phosphofructokinase (PFKII) inhibitor. Suppresses glycolysis by decreasing the level of fructose 2,6-bisphosphate, resulting in decreased visceral fat. Might be involved in the regulation of metabolism. Group: Biochemicals. Alternative Names: 2-Methylenebutanedioic Acid; Methylenesuccinic Acid; 2-Methylenebutanedioic Acid; 2-Methylenesuccinic Acid; 2-Propene-1,2-dicarboxylic Acid; 4-Hydroxy-2-methylene-4-oxobutanoic Acid; Methylenebutanedioic Acid; NSC 3357; Propylenedicarboxylic Acid. Grades: Highly Purified. CAS No. 97-65-4. Pack Sizes: 1g, 5g. Molecular Formula: C?H?O?. US Biological Life Sciences.
Worldwide
Native Porcine Aconitase
Aconitase catalyses the stereo-specific isomerization of Citrate to Isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentRations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity. Crude preparation containing aconitase activity. Applications: Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (ire-bp) and isomerases. Group: Enzymes. Synonyms: cis-aconitase; aconitase; Citrate hydro-lyase; Citrate (Isocitrate) hydro-lyase; EC 4.2.1.3; 9024-25-3; aconitate hydRatase. Enzyme Commission Number: EC 4.2.1.3. CAS No. 9024-25-3. Aconitase. Storage: -20°C. Source: Porcine heart. Species: Porcine. cis-aconitase; aconitase; Citrate hydro-lyase; Citrate (Isocitrate) hydro-lyase; EC 4.2.1.3; 9024-25-3; aconitate hydRatase. Cat No: NATE-0024.
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