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K-RasG12C-IN-1 is a novel and irreversible inhibitor of mutant K-rasG12C extracted from patent WO 2014152588 A1. Uses: Scientific research. Group: Signaling pathways. CAS No. 1629265-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18604.
K-RasG12C-IN-1
K-RasG12C-IN-1 is a novel and irreversible inhibitor of mutant K-rasG12C. Synonyms: K-RasG12C-IN-1. Grades: >98%. CAS No. 1629265-17-3. Molecular formula: C22H23Cl2N3O3. Mole weight: 448.34.
K-RasG12C-IN-2
K-RasG12C-IN-2 is a novel and irreversible inhibitor of mutant K-rasG12C. Synonyms: K-RasG12C-IN-2. Grades: >98%. CAS No. 1629267-75-9. Molecular formula: C21H27ClN4O3. Mole weight: 418.92.
K-RasG12C-IN-3
K-RasG12C-IN-3 is a novel and irreversible inhibitor of mutant K-rasG12C. Synonyms: K-RasG12C-IN-3. Grades: >98%. CAS No. 1629268-19-4. Molecular formula: C21H19Cl3N2O3. Mole weight: 453.75.
K-RasG12C-IN-4
K-RasG12C-IN-4, compound 1, is a potent Covalent Inhibitor of KRAS G12C [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2376328-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128771.
K-Ras(G12C) inhibitor 12
K-Ras(G12C) inhibitor 12 is a K-Ras(G12C) inhibitor. K-Ras(G12C) inhibitor 12 acts on H1792 cells with an EC50 of 0.32 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1469337-95-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18707.
K-Ras(G12C) inhibitor 12
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C). Synonyms: MDK-7958; MDK7958; MDK 7958; K-Ras(G12C) inhibitor 12. Grades: >98%. CAS No. 1469337-95-8. Molecular formula: C15H17ClIN3O3. Mole weight: 449.67.
K-Ras(G12C) inhibitor 6
K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2060530-16-5. Pack Sizes: 2 mg. Product ID: HY-107841.
K-Ras(G12C) inhibitor 9
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C). Synonyms: K-RAS inhibitor 9; N-(1-{2-[(4-chloro-5-iodo-2-methoxyphenyl)amino]acetyl}piperidin-4-yl)ethene-1-sulfonamide. Grades: >98%. CAS No. 1469337-91-4. Molecular formula: C16H21ClIN3O4S. Mole weight: 513.78.
K-Ras(G12C) inhibitor 9
K-Ras (G12C) inhibitor 9 is an allosteric inhibitor of the K-Ras (G12C) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1469337-91-4. Pack Sizes: 2 mg. Product ID: HY-12446.
6H05
6H05 is a selective inhibitor of oncogenic mutant K-Ras(G12C) without affecting wild-type K-Ras. Synonyms: 1-[2- (4-chlorophenyl) sulfanylacetyl]-N-[2-[2- (dimethylamino) ethyldisulfanyl]ethyl]piperidine-4-carboxamide6H051469338-01-9GTPL8023s7330ZINC205778612CS-3429; CS 3429; CS3429BC600592HY-12408; HY 12408; HY124081-{2-[(4-chlorophenyl)sulfanyl]acetyl}-N-(2-{[2-(dimethylamino)ethyl]disulf. CAS No. 1469338-01-9. Molecular formula: C20H30ClN3O2S3. Mole weight: 476.12.
ARS-1323 is an inhibitor of mutant K-rasG12C. Synonyms: ARS-1323; ARS 1323; ARS1323; 6-[6-chloro-8-fluoro-4-(4-prop-2-enoylpiperazin-1-yl)-1H-quinazolin-7-ylidene]-5-fluorocyclohexa-2,4-dien-1-one. CAS No. 1698024-73-5. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84.
ARS-1630
ARS-1630 is the R-enantiomer of ARS-1620. It is an inhibitor of mutant K-rasG12C. Synonyms: ARS-1630; ARS 1630; ARS1630; (R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one. CAS No. 1698055-86-5. Molecular formula: C21H17ClF2N4O2. Mole weight: 430.84.
KRpep-2d
KRpep-2d is a K-Ras(G12D) selective inhibitory cyclic peptide that has the potential as the treatment of cancers expressing K-Ras(G12C) mutant. Synonyms: s8499. Molecular formula: C108H182N44O25S2. Mole weight: 2561.01.
MDK30165
MDK30165, also known as K-Ras(G12C) Inhibitor 6, is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro. This compound has potential therapeutic application for diseases related to Ras signaling. Synonyms: N-(1-(2-(2,4-dichlorophenoxy)acetyl)piperidin-4-yl)-4-mercaptobutanamide; K-Ras(G12C) Inhibitor 6; MDK30165; MDK-30165; MDK 30165. CAS No. 2060530-16-5. Molecular formula: C17H22Cl2N2O3S. Mole weight: 405.33.
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