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Ketorolac, a non-selective COX inhibitor, is a non-steroidal anti-inflammatory drug. It shows inhibition of eicosanoid formation in HEL cells (COX-1) and LPS-stimulated Mono Mac 6 cells (COX-2), but does not significantly inhibit NO accumulation in supernatants of LPS-stimulated RAW 264.7 cells. It significantly inhibits thymidine incorporation of human osteoblasts (hOBs) upon 24 hours treatment in a dose-dependent manner, and inhibits proliferation and arrests cell cycle at G0/G1 phase in hOBs. Uses: Cyclooxygenase inhibitors. Synonyms: Acular LS; RS37619; RS 37619; RS-37619; Sprix; Toradol. Grades: >98%. CAS No. 74103-06-3. Molecular formula: C15H13NO3. Mole weight: 255.27.
Ketorolac. Group: Biochemicals. Grades: Highly Purified. CAS No. 74103-06-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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Ketorolac
Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC 50 s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RS37619. CAS No. 74103-06-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0580.
Ketorolac-Benzoylpyrrole Cyano Impurity
Ketorolac-Benzoylpyrrole Cyano Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1256844-82-2. Molecular formula: C14H12N2O. Mole weight: 224.26. Catalog: APB1256844822.
Ketorolac (calcium salt)
Ketorolac (calcium salt). Uses: For analytical and research use. Group: Impurity standards. CAS No. 167105-81-9. Molecular formula: C30H24CaN2O6. Mole weight: 548.61. Catalog: APB167105819.
Ketorolac EP Impurity B
Ketorolac EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113502-52-6. Molecular formula: C14H11NO2. Mole weight: 225.25. Catalog: APB113502526.
Ketorolac EP Impurity C
Ketorolac EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1026936-07-1. Molecular formula: C15H13NO3. Mole weight: 255.27. Catalog: APB1026936071.
Ketorolac EP Impurity E
Ketorolac EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 167105-80-8. Molecular formula: C19H22N2O5. Mole weight: 358.39. Catalog: APB167105808.
Ketorolac EP Impurity I
Ketorolac EP Impurity I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113502-55-9. Molecular formula: C14H13NO. Mole weight: 211.26. Catalog: APB113502559.
Ketorolac EP Impurity J
Ketorolac EP Impurity J. Uses: For analytical and research use. Group: Impurity standards. CAS No. 108061-03-6. Molecular formula: C17H17NO3. Mole weight: 283.33. Catalog: APB108061036.
Ketorolac Impurity 19
Ketorolac Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10087-64-6. Molecular formula: C8H8N2. Mole weight: 132.17. Catalog: APB10087646.
Ketorolac Impurity 21
Ketorolac Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 141054-42-4. Molecular formula: C15H15NO3. Mole weight: 257.29. Catalog: APB141054424.
Ketorolac Impurity 3
Ketorolac Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113502-54-8. Molecular formula: C14H13NO3. Mole weight: 243.26. Catalog: APB113502548.
Ketorolac Impurity 43
Ketorolac Impurity 43. Uses: For analytical and research use. Group: Impurity standards. CAS No. 141054-45-7. Molecular formula: C13H11NO3. Mole weight: 229.24. Catalog: APB141054457.
Ketorolac Impurity 45
Ketorolac Impurity 45. Uses: For analytical and research use. Group: Impurity standards. CAS No. 140947-23-5. Molecular formula: C20H21NO5. Mole weight: 355.39. Catalog: APB140947235.
Ketorolac Impurity A
an impurity of Ketorolac. Synonyms: Descarboxy 1-Hydroxy Ketorolac; (2,3-Dihydro-1-hydroxy-1H-pyrrolizin-5-yl)phenylmethanone; USP Ketorolac Related Compound B. Grades: > 95%. CAS No. 154476-25-2. Molecular formula: C14H13NO2. Mole weight: 227.27.
Ketorolac Impurity C
An isomeric impurity of Ketorolac. Synonyms: rac Ketorolac 6-Benzoyl Isomer; 6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid; (1RS)-6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. Grades: > 95%. CAS No. 1026936-07-1. Molecular formula: C15H13NO3. Mole weight: 255.28.
Ketorolac Impurity D
An impurity of the analgesic Ketorolac. Synonyms: rac 1-Methoxy Ketorolac; 5-Benzoyl-1-methoxy-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid. Grades: > 95%. CAS No. 1391053-45-4. Molecular formula: C16H15NO4. Mole weight: 285.30.
Ketorolac Impurity E
An impurity of Ketorolac. Synonyms: rac Ketoroloc Tris Amide Impurity; (±)-5-Benzoyl-2,3-dihydro-N-[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]-1H-pyrrolizine-1-carboxamide. Grades: > 95%. CAS No. 167105-80-8. Molecular formula: C19H22N2O5. Mole weight: 358.40.
Ketorolac Impurity F
An isomeric impurity of Ketorolac. Synonyms: rac Ketorolac 7-Benzoyl Isomer; 7-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid. Grades: > 95%. CAS No. 1391052-68-8. Molecular formula: C15H13NO3. Mole weight: 255.28.
Ketorolac Impurity G
An impurity of Ketorolac. Synonyms: rac 1-Hydroxy Ketorolac Methyl Ester; 5-Benzoyl-1-hydroxy-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid Methyl Ester. Grades: > 95%. CAS No. 1391051-90-3. Molecular formula: C16H15NO4. Mole weight: 285.30.
an impurity in the synthesis of (R)-Ketorolac. Synonyms: 1-Descarboxy Ketorolac; 2,3-Dihydro-1H-pyrrolizin-5-yl)phenylmethanone; USP Ketorolac Related Compound D. Grades: > 95%. CAS No. 113502-55-9. Molecular formula: C14H13NO. Mole weight: 211.27.
Ketorolaco is a potent, short acting nonsteroidal antiinflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It is a pyrrolizine carboxylic acid derivative structurally related to indomethacin. It is used as an analgesic. It acts by inhibiting the bodily synthesis of prostaglandins. It is also used to treat eye pain and to relieve the itchiness and burning of seasonal allergies. It was developed in 1989 by Syntex Corp. Uses: Ketorolaco is used as an analgesic. it is also used to treat eye pain and to relieve the itchiness and burning of seasonal allergies. Synonyms: ketorolac; Macril; (+-)-Ketorolac; 1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-; Toradol. Grades: 98%. CAS No. 66635-83-4. Molecular formula: C15H13NO3. Mole weight: 255.27.
Ketorolac Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ketorolac Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ketorolac Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ketorolac Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ketorolac Tromethamine is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively. Synonyms: 5-benzoyl-2,?3-dihydro-1H-pyrrolizine-1-carboxylic acid,compd. with 2-amino-2-(hydroxymethyl)?-1,?3-propanediol (1:1). CAS No. 74103-07-4. Molecular formula: C19H24N2O6. Mole weight: 376.4.
Ketorolac tromethamine salt
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H24N2O6. CAS No. 74103-07-4. Prepack ID 21205730-1g. Molecular Weight 376.4. See USA prepack pricing.
Ketorolac tromethamine salt
Ketorolac tromethamine salt. Group: Biochemicals. Alternative Names: Dolac; Ketanov; Ketorol. Grades: Highly Purified. CAS No. 74103-07-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C19H24N2O6. US Biological Life Sciences.
Worldwide
Ketorolac tromethamine salt
Ketorolac tromethamine salt (RS37619 tromethamine salt) is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC 50 s of 20 nM for COX-1 and 120 nM for COX-2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ketorolac Tromethamine; Ketorolac tris salt; RS37619 tromethamine salt. CAS No. 74103-07-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0138.
1-Descarboxy Ketorolac
1-Descarboxy Ketodolac is an impurity in the synthesis of (R)-Ketorolac (K235600). The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory. Group: Biochemicals. Grades: Highly Purified. CAS No. 113502-55-9. Pack Sizes: 2.5mg, 20mg. Molecular Formula: C14H13NO. US Biological Life Sciences.
Worldwide
1-Descarboxy Ketorolac-d4
1-Descarboxy Ketorolac-d4 is labelled 1-Descarboxy Ketodolac (D289435) which is an impurity in the synthesis of (R)-Ketorolac (K235600). The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C14H9D4NO, Molecular Weight: 215.28. US Biological Life Sciences.
Worldwide
1-Hydroxy-ketorolac
1-Hydroxy-ketorolac. Group: Biochemicals. Alternative Names: (2,3-Dihydro-1-hydroxy-1H-pyrrolizin-5-yl)phenylmethanone. Grades: Highly Purified. CAS No. 154476-25-2. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C14H13NO2. US Biological Life Sciences.
Worldwide
1-Keto-ketorolac
1-Keto-ketorolac. Group: Biochemicals. Alternative Names: 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one. Grades: Highly Purified. CAS No. 113502-52-6. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C14H11NO2. US Biological Life Sciences.
Worldwide
1-Keto Ketorolac
1-Keto Ketorolac. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one, Ketorolac Trometamol Imp. B (EP), Ketorolac USP RC C, Ketorolac USP Related Compound C,Ketorolac 1-Keto Anolog, Ketorolac 1-Keto Analog. CAS No. 113502-52-6. Pack Sizes: 10MG. IUPAC Name: 5-benzoyl-2,3-dihydropyrrolizin-1-one. Molecular formula: C14H11NO2. Mole weight: 225.24. Catalog: APS113502526. SMILES: O=C(c1ccccc1)c2ccc3C(=O)CCn23. Format: Neat. Shipping: Room Temperature.
1-Keto Ketorolac
Ketorolac impurity. Synonyms: 5-Benzoyl-2,3-dihydro-1H-pyrrolizin-1-one; USP Ketorolac Related Compound C. Grades: > 95%. CAS No. 113502-52-6. Molecular formula: C14H11NO2. Mole weight: 225.25.
1-Methoxy Ketorolac Methyl Ester
1-Methoxy Ketorolac Methyl Ester is an intermediate in synthesizing rac 1-Methoxy Ketorolac (M262725), an impurity of the analgesic Ketorolac (K235650). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C17H17NO4. US Biological Life Sciences.
Worldwide
4-Hydroxy ketorolac
A hydroxylated metabolite of Ketorolac in plasma. Synonyms: 2,3-Dihydro-5-(4-hydroxybenzoyl)-1H-pyrrolizine-1-carboxylic Acid; (+/-)-p-Hydroxyketorolac; p-Hydroxyketorolac. Grades: > 95%. CAS No. 111930-01-9. Molecular formula: C15H13NO4. Mole weight: 271.28.
Descarboxy 1-Hydroxy Ketorolac
Descarboxy 1-Hydroxy Ketorolac. Group: Biochemicals. Alternative Names: (2,3-Dihydro-1-hydroxy-1H-pyrrolizin-5-yl)phenylmethanone. Grades: Highly Purified. CAS No. 154476-25-2. Pack Sizes: 5mg. Molecular Formula: C14H13NO2, Molecular Weight: 227.26. US Biological Life Sciences.
Worldwide
rac 1-Hydroxy Ketorolac Methyl Ester
rac 1-Hydroxy Ketorolac Methyl Ester. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 2.5MG. Catalog: APS011633. Format: Neat. Shipping: Room Temperature.
rac 1-Methoxy Ketorolac
rac 1-Methoxy Ketorolac. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-Benzoyl-2,3-dihydro-1-methoxy-1H-pyrrolizine-1-carboxylic Acid, (1RS)-5-Benzoyl-1-methoxy-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid. CAS No. 1391053-45-4. IUPAC Name: 5-benzoyl-1-methoxy-2,3-dihydropyrrolizine-1-carboxylic acid. Molecular formula: C16H15NO4. Mole weight: 285.29. Catalog: APS1391053454. SMILES: COC1(CCn2c(ccc12)C(=O)c3ccccc3)C(=O)O. Format: Neat.
rac Ketorolac 6-Benzoyl Isomer
rac Ketorolac 6-Benzoyl Isomer. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid, (1RS)-6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic Acid. CAS No. 1026936-07-1. IUPAC Name: 6-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. Molecular formula: C15H13NO3. Mole weight: 255.27. Catalog: APS1026936071. SMILES: OC(=O)C1CCn2cc(cc12)C(=O)c3ccccc3. Format: Neat.
rac Ketorolac-d4
Labeled Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory. Group: Biochemicals. Alternative Names: 5-Benzoyl-2,3-dihydro-. Grades: Highly Purified. CAS No. 1216451-53-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac Ketorolac Tromethamine Salt.
Ketorolac is an analgesic; anti-inflammatory. Group: Biochemicals. Alternative Names: Dolac; Ketanov; Ketorol; Ketorolac trometamol; Lixidol; Tarazyn; Toradol; Toratex; Trometamol Ketorolac; Ketorolac Tris Salt. Grades: Highly Purified. CAS No. 74103-07-4. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
(R)-Ketorolac
(R)-Ketorolac is the R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory. Group: Biochemicals. Alternative Names: (1R)-. Grades: Highly Purified. CAS No. 66635-93-6. Pack Sizes: 5mg. US Biological Life Sciences.
(S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 μM for COX-1 and COX-2, respectively). Synonyms: (-)-Ketorolac; (1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. Grades: ≥98%. CAS No. 66635-92-5. Molecular formula: C15H13NO3. Mole weight: 255.3.
(S)-Ketorolac
(S)-Ketorolac is a nonsteroidal anti-inflammatory agent. (S)-ketorolac exhibits potent COX1 and COX2 enzyme inhibition [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Ketorolac. CAS No. 66635-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0580A.
(S)-Ketorolac
(S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory. Group: Biochemicals. Alternative Names: (1S)-. Grades: Highly Purified. CAS No. 66635-92-5. Pack Sizes: 5mg. US Biological Life Sciences.
Ketorolac Impurity. Group: Biochemicals. Alternative Names: rac Ketorolac 6-benzoyl isomer; 6-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid; Ketorolac impurity C. Grades: Highly Purified. CAS No. 1026936-07-1. Pack Sizes: 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
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2-Bromo-4-chloro-N-methyl-N-phenyl-butanamide
2-Bromo-4-chloro-N-methyl-N-phenyl-butanamide is an intermediate in synthesizing Ketorolac-d5 (K235617), which is a labeled analogue of Ketorolac, a Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory. Group: Biochemicals. Grades: Highly Purified. CAS No. 328936-18-1. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H13BrClNO. US Biological Life Sciences.
Worldwide
AN0128
AN0128, also known as CRM-0005 and ONT-0001, is a tumour necrosis factor alpha (TNF-α) inhibitor potentially for the treatment of atopic dermatitis. AN0128 showed promising combination of anti-bacterial and anti-inflammatory activities. This compound is now in clinical development for dermatological conditions. Daily application of AN0128 (1%) compared with controls reduced bone loss by 38 to 44% (P 0.05). The reduction in bone loss with AN0128 was similar to that achieved with a NSAID, ketorolac, and Total toothpaste containing triclosan. AN0128 also reduced the level of gingival inflammation 42% compared with the ligature only (P 0.05). The results indicate that AN0128 significantly reduces the formation of an inflammatory infiltrate and reduces bone loss, measured histologically and by micro-CT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AN-0128; CRM-0005; ONT-0001; AN0128; CRM0005; ONT0001; AN 0128; CRM 0005; ONT 0001. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 872044-70-7. Molecular formula: C20H16BCl2NO3. Mole weight: 400.06. Purity: >98%. IUPACName: ((bis(3-chloro-4-methylphenyl)boraneyl)oxy)(3-hydroxypyridin-2-yl)methanone. Canonical SMILES: CC1=CC=C(B(OC(C2=NC=CC=C2O)=O)C3=CC=C(C)C(Cl)=C3)C=C1Cl. Product ID: ACM872044707. Alfa Chemistry ISO 9001:2015 Certified.
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