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| Product | Description | |
|---|---|---|
| Kisspeptin-10 | Kisspeptin-10, also called Metastin (45-54), is a potent vasoconstrictor and endogenous ligand for the Kisspeptin receptor (KISS1, GPR54). Synonyms: Metastin (45-54); Kp-10; H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2; L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-phenylalaninamide; KISS1; Kisspeptin 10 (human). Grades: ≥95%. CAS No. 374675-21-5. Molecular formula: C63H83N17O14. Mole weight: 1302.44. |  |
| Kisspeptin 10 (dog) | Kisspeptin 10 (dog) is an endogenous ligand for the canine KISS1 receptor. It stimulates section of follicle stimulating hormone, estradiol and luteinizing hormone in vivo. Molecular formula: C65H87N17O14. Mole weight: 1330.51. | |
| Kisspeptin-10, human | Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression [1]. Uses: Scientific research. Group: Peptides. CAS No. 374675-21-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0254. |  |
| Kisspeptin 10 (rat) | Kisspeptin 10 (rat) is an endogenous ligand for the rodent KISS1 receptor. CAS No. 478507-53-8. Molecular formula: C63H83N17O15. Mole weight: 1318.45. | |
| Kisspeptin-10, rat acetate | Kisspeptin-10, rat acetate is an endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54). Synonyms: H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2.CH3CO2H; L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-tyrosinamide acetic acid; Rodent kiss-10Y acetate; Rodent kisspeptin 10Y acetate; Kisspeptin-10 (rat) acetate. Grades: ≥95%. Molecular formula: C65H87N17O17. Mole weight: 1378.45. | |
| Kisspeptin-10 Trifluoroacetate | Kisspeptin-10 Trifluoroacetate is a potent vasoconstrictor and endogenous ligand for the Kisspeptin receptor (KISS1, GPR54). Synonyms: Kisspeptin-10 TFA; Metastin (45-54) TFA; Kp-10 TFA; H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2.TFA; L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-phenylalaninamide Trifluoroacetate; KISS1 Trifluoroacetate; Kisspeptin 10 (human) Trifluoroacetate. Grades: >98%. Molecular formula: C63H83N17O14.C2HF3O2. Mole weight: 1416.46. | |
| Kisspeptin 234 | Kisspeptin 234 is a kisspeptin-10 analog and is used as a kisspeptin receptor antagonist. It inhibits kisspeptin-10 stimulation of inositol phosphate with IC50 value of 7 nM and release of gonadotrophin-releasing hormone. Synonyms: Ac-D-Ala-Asn-Trp-Asn-Gly-Phe-Gly-D-Trp-Arg-Phe-NH2; N-acetyl-D-alanyl-L-asparagyl-L-tryptophyl-L-asparagyl-glycyl-L-phenylalanyl-glycyl-D-tryptophyl-L-arginyl-L-phenylalaninamide. Grades: >98%. CAS No. 1145998-81-7. Molecular formula: C63H78N18O13. Mole weight: 1295.42. | |
| Kisspeptin 234 TFA | Kisspeptin 234 TFA, is a 10 amino acid peptide as well as a kisspeptin receptor (KISS1, GPR54) antagonist. Kisspeptin 234 TFA is an analog of Kisspeptin 10 [1]. Uses: Scientific research. Group: Peptides. CAS No. 1848962-29-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1196A. | |
| Kisspeptin-54 (27-54) (human) | Kisspeptin-54 (27-54) (human) is an LRF-amide motif containing a fragment of malignant melanoma metastasis-suppressor KiSS-1, that binds to human GPR54, a G-protein-coupled receptor. Compared with malignant melanoma metastasis-suppressor Kisspeptin-10, it shows lower agonistic potency to AXOR12. Synonyms: KiSS-1 (94-121) (human); H-Ile-Pro-Ala-Pro-Gln-Gly-Ala-Val-Leu-Val-Gln-Arg-Glu-Lys-Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2; L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-glutaminyl-glycyl-L-alanyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-arginyl-L-alpha-glutamyl-L-lysyl-L-alpha-aspartyl-L-leucyl-L-prolyl-L-asparagyl-L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-phenylalaninamide; Metastin (27-54) (human); Malignant melanoma metastasis-Suppressor KiSS-1 (94-121) (human). Grades: ≥95% by HPLC. CAS No. 1135442-77-1. Molecular formula: C149H226N42O39. Mole weight: 3229.65. | |
| Kisspeptin-54(human) | Kisspeptin-54(human) (Metastin(human)) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) binds to rat and human GPR54 receptors with K i values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) inhibits tumor metastasis and stimulates the secretion of gonadotropin (LH) and testosterone [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Peptides. Alternative Names: Metastin(human). CAS No. 374683-24-6. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-P1022. | |
| Kisspeptin-54 (human) trifluoroacetate salt | Kisspeptin-54 is an endogenous ligand for the orphan G protein-coupled receptor GPR54 (Kis = 1.81 and 1.45 nM for rat and human receptors respectively). It was shown to stimulate the hypothalamic-pituitary-gonadal (HPG) axis in animal models and humans. Synonyms: Metastin (human). Grades: ≥95%. Molecular formula: C258H401N79O78·xCF3COOH. Mole weight: 5857.43. | |
| Zebrafish Kisspeptin-1 | Zebrafish Kisspeptin-1 is the core sequence of the neuropeptide kisspeptin-1, which participate in the regulation of gonadotropin-releasing hormone (GnRH) release, and regulates the reproductive system [1]. Uses: Scientific research. Group: Peptides. CAS No. 1071873-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10419. | |
| Metastin (human) | Metastin (human) is an endogenous ligand to G-protein-coupled orphan receptors such as OT7T175 (also known as AXOR12) and GPR54. Kisspeptin-54 was initially termed as "metastin" because of its capacity to inhibit tumor metastasis. This peptide has been considered as the major product of the human KISS1 gene. It binds with high affinity to rat and human KISS1 receptors with Ki values of 1.80 and 1.45 nM respectively. Synonyms: Metastin (human); H-Gly-Thr-Ser-Leu-Ser-Pro-Pro-Pro-Glu-Ser-Ser-Gly-Ser-Arg-Gln-Gln-Pro-Gly-Leu-Ser-Ala-Pro-His-Ser-Arg-Gln-Ile-Pro-Ala-Pro-Gln-Gly-Ala-Val-Leu-Val-Gln-Arg-Glu-Lys-Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2; glycyl-L-threonyl-L-seryl-L-leucyl-L-seryl-L-prolyl-L-prolyl-L-prolyl-L-alpha-glutamyl-L-seryl-L-seryl-glycyl-L-seryl-L-arginyl-L-glutaminyl-L-glutaminyl-L-prolyl-glycyl-L-leucyl-L-seryl-L-alanyl-L-prolyl-L-histidyl-L-seryl-L-arginyl-L-glutaminyl-L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-glutaminyl-glycyl-L-alanyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-arginyl-L-alpha-glutamyl-L-lysyl-L-alpha-aspartyl-L-leucyl-L-prolyl-L-asparagyl-L-tyrosyl-L-asparagyl-L-tryptophyl-L-asparagyl-L-seryl-L-phenylalanyl-glycyl-L-leucyl-L-arginyl-L-phenylalaninamide; KP-54. Grades: ≥95%. CAS No. 374683-24-6. Molecular formula: C258H401N79O78. Mole weight: 5857.49. | |
| TAK-448 | TAK-448 is a KISS1R protein agonist as a oligopeptide analog of kisspeptin. In animal model, TAK-448 can stimulate LH/FSH release, whereas continuous sc exposure rapidly down-regulates the pituitary-gonadal axis, with rapid reduction of T levels in a dose-dependent manner. Phase II clinical trials for the treatment of Prostate cancer was discontinued. In Dec 2016, Takeda terminated a phase II trial in Hypogonadism (In adults, In the elderly) in USA because the study did not meet the primary endpoints. Uses: Hypogonadism;prostate cancer. Synonyms: MVT-602; Ac-D-Tyr-D-Trp-Asn-Thr-Phe-azaGly-Leu-Arg(Me)-Trp-NH2; RVT-602; RVT 602; TAK 448; RVT602; TAK448; N-acetyl-D-tyrosyl-(4R)-4-hydroxy-L-prolyl-L-asparaginyl-L-threonyl-L-phenylalanyl-2-azaglycyl-L-leucyl-N5-(imino(methylamino)methyl)-L-ornithyl-L-Tryptophanamide; Istaroxime; (2S,5S,8S,14S,17S,20S)-20-[({(2S,4R)-1-[(2R)-2-Acetamido-3-(4-hydroxyphenyl)propanoyl]-4-hydroxy-2-pyrrolidinyl}carbonyl)amino]-14-benzyl-17-(1-hydroxyethyl)-2-(1H-indol-3-ylmethyl)-8-isobutyl-5-[3-(N'-methylcarbamimidamido)propyl]-4,7,10,13,16,19-hexaoxo-3,6,9,11,12,15,18-heptaazadocosane-1,22-diamide. Grades: 98%. CAS No. 1234319-68-6. Molecular formula: C58H80N16O14. Mole weight: 1225.36. | |
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