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KYL. Group: Biochemicals. Grades: Purified. CAS No. 676657-00-4. Pack Sizes: 1mg. US Biological Life Sciences.
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KYL
KYL is a selective and potent EphA4 receptor tyrosine kinase antagonist with Kd value of 0.8 μM. It inhibits EphA4-EphrinA5 interactions with IC50 value of 6.34 μM. It prevents AβO induced dendritic spine loss and synaptic damage. It also prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows a long half life in cell culture media. It has the neuroprotective effect. Synonyms: H-Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu-OH; L-lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-L-leucine; HY-P2264. Grades: ≥95%. CAS No. 676657-00-4. Molecular formula: C74H108N14O17. Mole weight: 1465.75.
KYL acetate
KYL is a selective and potent EphA4 receptor tyrosine kinase antagonist with a Kd value of 0.8 μM. It inhibits EphA4-EphrinA5 interactions with an IC50 value of 6.34 μM. It prevents AβO induced dendritic spine loss and synaptic damage. It also prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. It shows a long half-life in cell culture media. It has a neuroprotective effect. Synonyms: L-Leucine, L-lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-, acetate; L-Lysyl-L-tyrosyl-L-leucyl-L-prolyl-L-tyrosyl-L-tryptophyl-L-prolyl-L-valyl-L-leucyl-L-seryl-L-seryl-L-leucine acetate; KYL peptide acetate; Lys-Tyr-Leu-Pro-Tyr-Trp-Pro-Val-Leu-Ser-Ser-Leu acetate salt. Grades: ≥95%. Molecular formula: C74H108N14O17.C2H4O2. Mole weight: 1525.78.
Daminozide is a highly selective inhibitor of the human 2-oxoglutarate (JmjC) histone demethylases KDM2A, PHF8, and KDM7A with IC50 values of 1.5, 0.55, and 2.1 μM, respectively. When tested for inhibition of other demethylase subfamily members (KDM3, KDM4, KDM5, KDM6) and other 2OG oxygenases (FIH, PHD2, BBOX1), daminozide was considerably less potent (IC50s > 100 μM). Daminozide is known to retard plant growth and was widely used in the 1960s for agricultural and horticultural applications to control plant size and fruit ripening before it was withdrawn because of carcinogenicity concerns. Synonyms: Alar; B 995; DMASA; SADH; Succinic Acid; Aminozide; Kylar; DIMG. Grades: >98%. CAS No. 1596-84-5. Molecular formula: C6H12N2O3. Mole weight: 160.17.
Xylitol
Pharmacopeia & Metrological Institutes Standards; API Standards; European Pharmacopoeia (Ph. Eur.); Pharmacopoeial Standards. Uses: For analytical and research use. Group: Reagents. Alternative Names: Xylitol, Meso-xylitol, C-Xylidex CR 16055, DL-Xylitol, Eutrit, Fluorette, Klinit, Kylit, NSC 25283, Wood sugar alcohol, X 0018, Xylisorb, Xylisorb 300, Xylisorb 700, Xylit, Xylit XC, Xylitab 100, Xylitab 300, Xylitab DC, Xylite, Xylite (sugar), Xylitol C, Xylitol CM 90, Xylitol P, Xyliton, meso-Xylitol, xylo-Pentitol. CAS No. 87-99-0. Pack Sizes: 1G. IUPAC Name: (2S,4R)-pentane-1,2,3,4,5-pentol.