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1g Pack Size. Group: Sugars. Formula: C6H12O5. CAS No. 2438-80-4. Prepack ID 90028077-1g. Molecular Weight 164.16. See USA prepack pricing.
L-(-)-Fucose
L-(-)-Fucose. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-Deoxy-α-L-galactopyranose. Product Category: Heterocyclic Organic Compound. Appearance: Solid. CAS No. 6696-41-9. Molecular formula: C6H12O5. Mole weight: 164.16. Purity: 0.98. IUPACName: (2R,3S,4R,5S,6S)-6-methyloxane-2,3,4,5-tetrol. Canonical SMILES: C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O)O)O)O. Product ID: ACM6696419. Alfa Chemistry ISO 9001:2015 Certified. Categories: L-fucose isomerase.
1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose
1,2,3,4-Tetra-O-acetyl-5-alkynyl-L-fucose is a specialized chemical often involved in studies related to cancer treatments. It's a key component in synthesizing innovative pharmaceuticals aimed at combating tumor growth and expansion. Synonyms: 1,2,3,4-Tetra-O-acetyl-6,7-dideoxy-L-galacto-hept-6-ynopyranose. CAS No. 935658-91-6. Molecular formula: C15H18O9. Mole weight: 342.30.
1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucose
2,6-Dideoxy-2-fluoro-L-galactopyranose 1,3,4-Triacetate is a reactant in the preparation of β-purine-diphosphate sugars (GDP-fucose-analogs). Synonyms: Peracetylated 2-fluoro 2-deoxy-L-fucose; (3S,4R,5R,6S)-3-fluoro-6-methyl-tetrahydro-2H-pyran-2,4,5-triyl triacetate; 2-deoxy-2-fluorofucose peracetate; 2-fluorofucose triacetate. Grade: ≥ 97%. CAS No. 188783-78-0. Molecular formula: C12H17FO7. Mole weight: 292.26.
2,3,4-Tri-O-benzyl-L-fucopyranose, a chemical compound, serves as a pivotal intermediate for the synthesis of diverse carbohydrates and glycoconjugates. Its therapeutic potential manifests in tackling select cancers, inflammation and microbial infections, offering a promising outlook to the field of medicine and bio-chemistry. The multifaceted usage rooted in its strategic molecular composition and unique properties unlocks new avenues for research and treatment development. Synonyms: 6-Deoxy-2,3,4-tris-O-(phenylmethyl)-L-galactose; 2,3,4-Tri-O-benzyl-L-fucopyranose; (2S,3R,4R,5S)-2,3,4-Tris(benzyloxy)-5-hydroxyhexanal; 2,3,4-Tris-O-(phenylmethyl)-L-fucose; 6-Deoxy-2,3,4-tris-O-benzyl-L-galactose. Grade: ≥95%. CAS No. 60431-34-7. Molecular formula: C27H30O5. Mole weight: 434.52.
2,3-Di-O-benzyl-4-deoxy-L-fucose
2,3-Di-O-benzyl-4-deoxy-L-fucose is a vital component in the biomedical industry. Its applications include its use in the synthesis of potential antitumor drug derivatives and the treatment of various diseases related to irregular glycogen metabolism. Synonyms: 2,3-Di-O-benzyl-4,6-dideoxy-L-xylo-hexose. CAS No. 191036-43-8. Molecular formula: C20H24O4. Mole weight: 328.40.
2-Amino-2-deoxy-L-fucose
2-Amino-2-deoxy-L-fucose, a monosaccharide of paramount significance, intricately participates in the inherent complexity of glycan biosynthesis. Its versatile attributes serve as a substrate for fucosyltransferases, inducing the production of fucosylated glycans, a heterogeneous group of biomolecules, meticulously regulating critical biological processes, including cell adhesion and signal transduction. Researchers have also investigated its potential therapeutic applications in ameliorating cancer and inflammatory diseases. Synonyms: 2-Amino-2,6-dideoxy-L-galactose; L-Fucosamine. CAS No. 7577-62-0. Molecular formula: C6H13NO4. Mole weight: 163.17.
2-Deoxy-2-fluoro-L-fucose
2-Deoxy-2-fluoro-L-fucose, an indispensable compound in the biomedical sector, finds diverse therapeutic applications. Its pivotal role lies in the development of pharmaceutical agents combating ailments like cancer, inflammation, and viral infections. Synonyms: 2,6-dideoxy-2-fluoro-L-Galactose. Grade: ≥95%. CAS No. 70763-62-1. Molecular formula: C6H11FO4. Mole weight: 166.15.
2-Deoxy-2-fluoro-L-fucose
2-Deoxy-2-fluoro-L-fucose, an L-fucose analog, is a fucosylation inhibitor. 2-Deoxy-2-fluoro-L-fucose inhibits de novo synthesis of GDP-fucose in mammalian cells. Fucosylation is a relatively well-defined biomarker for progression in many human cancers; for example, pancreatic and hepatocellular carcinoma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70763-62-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116705.
2-Deoxy-L-fucose
2-Deoxy-L-fucose is a meticulously crafted synthetic sugar molecule, emerging as an indispensable tool for probing the elusive intricacies of protein-carbohydrate interactions and glycosylation processes. Synonyms: 2,6-Dideoxyhexose; 2,6-Dideoxy-L-lyxo-hexose; SCHEMBL3996144; L-lyxo-Hexose, 2,6-dideoxy-; DTXSID30940809. CAS No. 19165-06-1. Molecular formula: C6H12O4. Mole weight: 148.16.
2F-Peracetyl-Fucose
2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) acts as a potent fucosyltransferase (FUT) inhibitor[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos. CAS No. 188783-78-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W096600.
4-Deoxy-L-fucose
4-Deoxy-L-fucose, known as a fundamental substance, finds extensive application within the biomedical sector owing to its multifarious uses. It assumes a pivotal function in the formulation of pharmaceutical agents tailored to combat distinct ailments. Notably, its incorporation in drug synthesis aims to tackle maladies encompassing cancer, inflammation, and bacteriosis. The indispensability of this compound arises from its unparalleled attributes, thereby rendering it indispensable in the fabrication of efficacious biomedical remedies. Synonyms: 4,6-Dideoxy-L-xylo-hexose. CAS No. 61244-62-0. Molecular formula: C6H12O4. Mole weight: 148.16.
5-Alkynyl-L-fucose
5-Alkynyl-L-fucose is a remarkable compound harnessed for studying an array of cell adhesion, immune response and glycosylation-associated ailments. Its wide-ranging utilities span from unraveling intricate cellular processes to devising precision-focused cancer and immune disorder research. Synonyms: L-Altro-6,7-dideoxy-hept-6-ynose. CAS No. 1193251-61-4. Molecular formula: C7H10O5. Mole weight: 174.15.
5-Thio-L-fucose
5-Thio-L-fucose, a sugar derivative with rare properties, has shown potential as an anti-tumor agent. Its unique ability to impede tumor proliferation and trigger programmed cell death in cancerous cells makes it a promising candidate for drug development. Research suggests its effectiveness in combating breast and colon cancers among others. Synonyms: 5-thio-l-fucose; SCHEMBL1697421. Molecular formula: C6H12O4S. Mole weight: 180.22.
The enzyme, isolated from the bacterium Streptomyces galilaeus, is involved in the biosynthesis of other aclacinomycins. Also acts on idarubicin. It will slowly add a second 2-deoxy-L-fucose unit to aclacinomycin S in vitro. Group: Enzymes. Synonyms: AknK. Enzyme Commission Number: EC 2.4.1.327. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2564; aclacinomycin-T 2-deoxy-L-fucose transferase; EC 2.4.1.327; AknK. Cat No: EXWM-2564.
a-L-Fucose-1-phosphate
a-L-Fucose-1-phosphate is an indispensable biochemical compound prevalent in the biomedical industry orchestrating the research and development of glycans and glycoconjugates, paramount for regulating cell signaling and immune response dynamics. Molecular formula: C6H13O8P. Mole weight: 244.14.
a-L-Fucose-1-phosphate bis(cyclohexylammonium) salt
A paramount constituent in the field of biomedicine, a-L-Fucose-1-phosphate bis(cyclohexylammonium) salt serves as a pivotal factor in the production and analysis of enzymes related to carbohydrate metabolism. Its crucial role further extends to research on liver glycogen storage diseases, as well as in the treatment of select forms of malignancy. Indeed, this reagent proves itself to be a fundamental cornerstone in contemporary biomedical research. Synonyms: α-L-Fucose-1-phosphate (cyclohexylammonium salt); 6-Deoxy-α-L-Galactopyranose 1-(Dihydrogen Phosphate) Cyclohexanamine (1:2); α-L-Fucopyranose 1-(Dihydrogen Phosphate) Di(cyclohexylammonium) Salt; α-L-Fucopyranosyl 1-Phosphate Di(cyclohexylammonium) Salt; α-L-Fucopyranosyl Phosphate Di(cyclohexylammonium) Salt. Grade: ≥98%. CAS No. 24333-03-7. Molecular formula: C6H13O8P.2C6H13N. Mole weight: 442.48.
Alpha-L-(-)-fucose 1-phosphate di(cylohexylammonium)salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: |A-L-(-)-Fucose 1-phosphate bis(cyclohexylammonium) salt, 24333-03-7. Product Category: Heterocyclic Organic Compound. CAS No. 24333-03-7. Molecular formula: C18H39N2O8P. Mole weight: 442.48. Purity: 0.96. IUPACName: cyclohexanamine;[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl] dihydrogen phosphate. Canonical SMILES: CC1C(C(C(C(O1)OP(=O)(O)O)O)O)O.C1CCC(CC1)N.C1CCC(CC1)N. Product ID: ACM24333037. Alfa Chemistry ISO 9001:2015 Certified.
GDP-L-fucose
GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway. GDP-L-fucose is associated with diabetes in rats[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 15839-70-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134433.
GDP-L-fucose
GDP-L-fucose is a pivotal biomolecule acting as a precursory compound to facilitate the synthesis of fucose-containing glycoconjugates implicated in diverse cellular phenomena. Its exceptional significance lies in the research of glycosylation patterns, evaluation of protein functioning repercussions and investigation into possible therapeutic approaches targeting conditions like cancer and inflammation. Synonyms: GDP-b-L-fucose; Guanosine 5-diphospho-b-L-fucose; GDP-Fucose; Guanosine diphosphofucose; Guanosine 5'-diphospho-beta-L-fucopyranose; guanosine 5'-[3-(6-deoxy-beta-L-galactopyranosyl) dihydrogen diphosphate]. Grade: 95%. CAS No. 15839-70-0. Molecular formula: C16H25N5O15P2. Mole weight: 589.34.
GDP-L-fucose diammonium salt
GDP-L-fucose diammonium salt is an indispensable compound, serving as a vital substrate for fucosyltransferase. This compound intricately contributes to the biosynthesis of fucosylated glycans. Molecular formula: C15H23N5O15P2.N2H8. Mole weight: 623.41.
Both human and Escherichia coli enzymes can use NADH in place of NADPH to a slight extent. Group: Enzymes. Synonyms: GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing). Enzyme Commission Number: EC 1.1.1.271. CAS No. 113756-18-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0178; GDP-L-fucose synthase; EC 1.1.1.271; 113756-18-6; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing). Cat No: EXWM-0178.
L-fucokinase/GDP-fucose pyrophos-phorylase (FKP) is an enzyme that catalyzes the chemical reaction. L-fucokinase/GDP-fucose pyrophos-phorylase (FKP) has substrate of L-fucose. L-fucokinase/GDP-fucose pyrophos-phorylase (FKP) induces L-fucose phosphorylation to form L-fucose-L-phosphate [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37278-00-5. Pack Sizes: 5 U; 10 U; 25 U. Product ID: HY-E70026.
L-fucokinase/GDP-fucose pyrophosphorylase from Bacteroides fragilis, Recombinant
In enzymology, a fucokinase (EC 2.7.1.52) is an enzyme that catalyzes the chemical reaction: ATP + L-fucose ? ADP + beta-L-fucose 1-phosphate. Thus, the two substrates of this enzyme are ATP and L-fucose, whereas its two products are ADP and beta-L-fucose 1-phosphate. In enzymology, a fucose-1-phosphate guanylyltransferase (EC 2.7.7.30) is an enzyme that catalyzes the chemical reaction: GTP + beta-L-fucose 1-phosphate ? diphosphate + GDP-L-fucose. Thus, the two substrates of this enzyme are GTP and beta-L-fucose 1-phosphate, whereas its two products are diphosphate and GDP-L-fucose. Group: Enzymes. Synonyms: fucose kinase; L-fucose kinase; L-fucokinase; ATP:6-deoxy-L-galactose 1-phosphotransferase; ATP:L-fuco. Enzyme Commission Number: EC 2.7.1.52/2.7.730. Purity: min 95% by SDS-PAGE. L-Fucokinase/GDP-fucose Pyrophosphorylase. Mole weight: 106 kDa. Source: E. coli. Species: Bacteroides fragilis. fucose kinase; L-fucose kinase; L-fucokinase; ATP:6-deoxy-L-galactose 1-phosphotransferase; ATP:L-fucose 1-phosphotransferase; fucokinase; EC 2.7.1.52; GDP fucose pyrophosphorylase; guanosine diphosphate L-fucose pyrophosphorylase; GDP-L-fucose pyrophosphorylase; GDP-fucose pyrophosphorylase; GTP:L-fucose-1-phosphate guanylyltransferase; fucose-1-phosphate guanylyltransferase; EC 2.7.7.30. Cat No: NATE-1495.
L-Fucose
L-Fucose. Group: Biochemicals. Alternative Names: 6-deoxy-L-galactose. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
L-Fucose
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardscarbohydrates.
L-Fucose-1-13C
L-Fucose-1-13C. Group: Biochemicals. Alternative Names: 6-Deoxy-L-galactose-1-13C; (-)-Fucose-1-13C; 6-Deoxy-L-galactose-1-13C; 6-Desoxygalactose-1-13C; Fucose-1-13C; L-(-)-Fucose-1-13C; L-Galactomethylose-1-13C. Grades: Highly Purified. CAS No. 83379-38-8. Pack Sizes: 2.5mg. Molecular Formula: C513CH12O5, Molecular Weight: 165.15. US Biological Life Sciences.
Worldwide
L-Fucose-1-[13C]
L-Fucose-[1-13C] is the labelled analogue of L-Fucose. L-Fucose are also added to a variety of cosmetics, drugs and dietary supplements. Synonyms: 6-Deoxy-L-galactose-1-13C; L-Fucose-1-13C; L-[1-13C]fucose; 6-deoxy-L-[1-13C]galactose; (-)-Fucose-1-13C; 6-Desoxygalactose-1-13C; Fucose-1-13C; L-(-)-Fucose-1-13C; L-Galactomethylose-1-13C. Grade: 99% (CP); 99% atom 13C. CAS No. 83379-38-8. Molecular formula: C5[13C]H12O5. Mole weight: 165.15.
L-Fucose-13C6
Isotope-labeled L-Fucose, an hexose deoxy sugar that is claimed to have applications in cosmetics and pharmaceuticals. Group: Biochemicals. Alternative Names: 6-Deoxy-L-galactose-13C6; (-)-Fucose-13C6; 6-Deoxy-L-galactose--13C6; 6-Desoxygalactose-13C6; Fucose-13C6; L-(-)-Fucose-13C6; L-Galactomethylose-13C6. Grades: Highly Purified. CAS No. 478518-52-4. Pack Sizes: 1mg. Molecular Formula: ¹³C?H??O?, Molecular Weight: 170.11. US Biological Life Sciences.
Worldwide
L-Fucose-[13C6]
L-Fucose-[13C6] is the labelled analogue of L-Fucose. L-Fucose is also added to a variety of cosmetics, drugs and dietary supplements. Synonyms: 6-Deoxy-L-galactose-13C6; (-)-Fucose-13C6; 6-Deoxy-L-galactose-13C6; 6-Desoxygalactose-13C6; Fucose-13C6; L-(-)-Fucose-13C6; L-Galactomethylose-13C6. CAS No. 478518-52-4. Molecular formula: [13C]6H12O5. Mole weight: 170.11.
L-Fucose-[2-13C]
L-Fucose-[2-13C] is the labelled analogue of L-Fucose. L-Fucose is also added to a variety of cosmetics, drugs and dietary supplements. Synonyms: 6-Deoxy-L-galactose-2-13C; (-)-Fucose-2-13C; 6-Deoxy-L-galactose-2-13C; 6-Desoxygalactose-2-13C; Fucose-2-13C; L-(-)-Fucose-2-13C; L-Galactomethylose-2-13C. CAS No. 83379-37-7. Molecular formula: C5[13C]H12O5. Mole weight: 165.15.
L-Fucose-2-13C
L-Fucose-2-13C. Group: Biochemicals. Alternative Names: 6-Deoxy-L-galactose-2-13C; (-)-Fucose-2-13C; 6-Deoxy-L-galactose-2-13C; 6-Desoxygalactose-2-13C; Fucose-2-13C; L-(-)-Fucose-2-13C; L-Galactomethylose-2-13C. Grades: Highly Purified. CAS No. 83379-37-7. Pack Sizes: 2.5mg. Molecular Formula: C513CH12O5, Molecular Weight: 165.15. US Biological Life Sciences.
Worldwide
L-Fucose-[3-13C]
L-Fucose-[3-13C] is the labelled analogue of L-Fucose. L-Fucose is also added to a variety of cosmetics, drugs and dietary supplements. Synonyms: 6-Deoxy-L-galactose-3-13C; (-)-Fucose-3-13C; 6-Deoxy-L-galactose-3-13C; 6-Desoxygalactose-3-13C; Fucose-3-13C; L-(-)-Fucose-3-13C; L-Galactomethylose-3-13C. CAS No. 478518-50-2. Molecular formula: C5[13C]H12O5. Mole weight: 165.15.
L-Fucose-3-13C
L-Fucose-3-13C. Group: Biochemicals. Alternative Names: 6-Deoxy-L-galactose-3-13C; (-)-Fucose-3-13C; 6-Deoxy-L-galactose-3-13C; 6-Desoxygalactose-3-13C; Fucose-3-13C; L-(-)-Fucose-3-13C; L-Galactomethylose-3-13C. Grades: Highly Purified. CAS No. 478518-50-2. Pack Sizes: 1mg. Molecular Formula: C513CH12O5, Molecular Weight: 165.15. US Biological Life Sciences.
Worldwide
L-Fucose-[6-13C]
L-Fucose-[6-13C] is the labelled analogue of L-Fucose. L-Fucose is also added to a variety of cosmetics, drugs and dietary supplements. Synonyms: 6-Deoxy-L-galactose-6-13C; (-)-Fucose-6-13C; 6-Deoxy-L-galactose-6-13C; 6-Desoxygalactose-6-13C; Fucose-6-13C; L-(-)-Fucose-6-13C; L-Galactomethylose-6-13C. CAS No. 478518-51-3. Molecular formula: C5[13C]H12O5. Mole weight: 165.15.
L-Fucose-6-13C
L-Fucose-6-13C. Group: Biochemicals. Alternative Names: 6-Deoxy-L-galactose-6-13C; (-)-Fucose-6-13C; 6-Deoxy-L-galactose-6-13C; 6-Desoxygalactose-6-13C; Fucose-6-13C; L-(-)-Fucose-6-13C; L-Galactomethylose-6-13C. Grades: Highly Purified. CAS No. 478518-51-3. Pack Sizes: 1mg. Molecular Formula: C513CH12O5, Molecular Weight: 165.15. US Biological Life Sciences.
Worldwide
L-fucose isomerase
Requires a divalent metal ion (the enzyme from the bacterium Escherichia coli prefers Mn2+). The enzyme binds the closed form of the sugar and catalyses ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene-diol mechanism. The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose. The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. Group: Enzymes. Enzyme Commission Number: EC 5.3.1.25. CAS No. 60063-83-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5464; L-fucose isomerase; EC 5.3.1.25; 60063-83-4. Cat No: EXWM-5464.
L-fucose mutarotase
This enzyme shows no 1-epimerase activity with D-glucose, L-rhamnose and D-fucose (cf. EC 5.1.3.3, aldose 1-epimerase). Group: Enzymes. Synonyms: FucU; fucose mutarotase; FucM. Enzyme Commission Number: EC 5.1.3.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5415; L-fucose mutarotase; EC 5.1.3.29; FucU; fucose mutarotase; FucM. Cat No: EXWM-5415.
1,2,3,4-Tetra-O-acetyl-L-fucopyranose
1,2,3,4-Tetra-O-acetyl-L-fucopyranose is an instrumental carbohydrate derivative, playing a quintessential role in antigen and antibody research. Synonyms: L-Galactopyranose, 6-deoxy-, 1,2,3,4-tetraacetate; L-Galactopyranose, 6-deoxy-, tetraacetate; L-Fucose tetraacetate; NSC 119108. CAS No. 24332-95-4. Molecular formula: C14H20O9. Mole weight: 332.30.
1,2-α-L-fucosidase
Highly specific for non-reducing terminal L-fucose residues linked to D-galactose residues by a 1,2-α-linkage. Not identical with EC 3.2.1.111 1,3-α-L-fucosidase. Group: Enzymes. Synonyms: almond emulsin fucosidase; α-(1?2)-L-fucosidase. Enzyme Commission Number: EC 3.2.1.63. CAS No. 37288-45-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3927; 1,2-α-L-fucosidase; EC 3.2.1.63; 37288-45-2; almond emulsin fucosidase; α-(1?2)-L-fucosidase. Cat No: EXWM-3927.
1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-a-L-fucopyranose - an organic molecule possessing diverse biological activities, has been regarded as a promising candidate for developing new-generation therapeutic agents. The structural resemblance of this compound to fucose renders it an ideal candidate for targeting fucose-associated physiological processes that underlie pathological conditions like inflammation and tumor metastasis. Its potential as a therapeutic agent has been widely explored, primarily owing to its ability to modulate fucosylation-mediated interactions between cell surface glycoconjugates and their cognate ligands, thereby exhibiting encouraging results. Synonyms: 2-Fluoro-a-L-fucose triacetate; 1,3,4-Tri-O-acetyl-2,6-dideoxy-2-fluoro-a-L-galactopyranose. CAS No. 74554-12-4. Molecular formula: C12H17FO7. Mole weight: 292.26.
2,6-Dideoxy-2-fluoro-L-galactopyranose 1,3,4-Triacetate is a reactant in the preparation of β-purine-diphosphate sugars (GDP-fucose-analogs). Group: Biochemicals. Grades: Highly Purified. CAS No. 188783-78-0. Pack Sizes: 25mg, 250mg. Molecular Formula: C12H17FO7, Molecular Weight: 292.26. US Biological Life Sciences.
2,6-Dideoxy-2-fluoro-L-galactopyranose (α, β Mixture) is used in the preparation of GDP-2-deoxy-2-fluoro- β-L-fucose, a human α-1,3-fucosyltransferase V inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C6H11FO4, Molecular Weight: 166.15. US Biological Life Sciences.
2,6-Dideoxy-2-fluoro-L-galactopyranose (α,β Mixture) is used in the preparation of GDP-2-deoxy-2-fluoro-β-L-fucose, a human α-1,3-fucosyltransferase V inhibitor. Synonyms: 2-Deoxy-2-fluoro-L-fucose. Molecular formula: C6H11FO4. Mole weight: 166.15.
Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. This enzyme fucosylates on O-3 of an N-acetylglucosamine that carries a galactosyl group on O-4, unlike EC 2.4.1.65, 3-galactosyl-N-acetylglucosaminide 4-α-L-fucosyltransferase, which fucosylates on O-4 of an N-acetylglucosamine that carries a galactosyl group on O-3. Group: Enzymes. Synonyms: Lewis-negative α-3-fucosyltransferase; plasma α-3-fucosyltransferase; guanosine diphosphofucose-glucoside α1?3-fucosyltransferase; galactoside 3-fu. Enzyme Commission Number: EC 2.4.1.152. CAS No. 39279-34-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2378; 4-galactosyl-N-acetylglucosaminide 3-α-L-fucosyltransferase; EC 2.4.1.152; 39279-34-0; Lewis-negative α-3-fucosyltransferase; plasma α-3-fucosyltransferase; guanosine diphosphofucose-glucoside α1?3-fucosyltransferase; galactoside 3-fucosyltransferase; GDP-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase; GDP-β-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-L-fucosyltransferase; GDP-β-L-fucose:1,4-β-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-α-L-fucosyltransferase. Cat No: EXWM-2378.
aklavinone 7-L-rhodosaminyltransferase
Isolated from the bacterium Streptomyces galilaeus. Forms a complex with its accessory protein AknT, and has very low activity in its absence. The enzyme can also use dTDP-2-deoxy-β-L-fucose. Involved in the biosynthesis of other aclacinomycins. Group: Enzymes. Synonyms: AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Enzyme Commission Number: EC 2.4.1.326. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2563; aklavinone 7-L-rhodosaminyltransferase; EC 2.4.1.326; AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Cat No: EXWM-2563.
aldose 1-dehydrogenase [NAD(P)+]
The enzyme from the archaeon Sulfolobus solfataricus shows broad specificity towards aldoses (D-glucose, D-galactose, D-xylose, L-arabinose, 6-deoxy-D-glucose, D-fucose) and can utilize NAD+ and NADP+ with similar catalytic efficiency. It is involved in aldose catabolism via the branched variant of the Entner-Doudoroff pathway. Group: Enzymes. Enzyme Commission Number: EC 1.1.1.359. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0275; aldose 1-dehydrogenase [NAD(P)+]; EC 1.1.1.359. Cat No: EXWM-0275.
α-1,2-colitosyltransferase
The enzyme, characterized from the bacterium Escherichia coli O55:H7, participates in the biosynthesis of an O-antigen. The reaction involves anomeric inversion, and does not require any metal ions. The enzyme is highly specific towards the acceptor, exclusively recognizing lacto-N-biose, but can accept GDP-L-fucose as the donor with almost the same activity as with GDP-β-L-colitose. Group: Enzymes. Synonyms: wbgN (gene name). Enzyme Commission Number: EC 2.4.1.341. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2580; α-1,2-colitosyltransferase; EC 2.4.1.341; wbgN (gene name). Cat No: EXWM-2580.
α-1,3/4-fucosyltransferase from Helicobacter mustelae, Recombinant
A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. Group: Enzymes. Synonyms: Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Enzyme Commission Number: EC 2.4.1.65. CAS No. 37277-69-3. Purity: min 95% by SDS-PAGE. α-fucosyltransferase. Source: E. coli. Species: Helicobacter mustelae. Alpha-(1,3/1,4) fucosyltransferase III; Alpha-(1->4)-L-fucosyltransferase; Alpha-4-L-fucosyltransferase; Beta-acetylglucosaminylsaccharide fucosyltransferase; Blood group Lewis alpha-4-fucosyltransferase; Blood-group substance Le(a)-dependent fucosyltransferase; FucT-II; Galactoside 3(4)-L-fucosyltransferase. Cat No: NATE-1484.
α-1-3,4 Fucosyltransferase, helicobacter pylori
alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) (EC 2.4.1.65) (Hp3/4FT) can be found in Helicobacter pylori. alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) catalyzes fucose transfer from donor GDP-beta-l-fucose to the GlcNAc [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: α-1-3,4 FucT; Hp3/4FT. CAS No. 37277-69-3. Pack Sizes: 1 U; 25 U; 5 U. Product ID: HY-E70058.
α-1,3-fucosyltransferase from Helicobacter pylori, Recombinant
A fucosyltransferase is an enzyme that transfers an L-fucose sugar from a GDP-fucose (guanosine diphosphate-fucose) donor substrate to an acceptor substrate. Group: Enzymes. Synonyms: glycoprotein 3-alpha-L-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc alpha1,3-fucosyltransferase; EC 2.4.1.214; Glycoprotein 3-alpha-L-fucosyltransferase. Enzyme Commission Number: EC 2.4.1.214. CAS No. 68247-53-0. Purity: min 95% by SDS-PAGE. α-fucosyltransferase. Source: E. coli. Species: Helicobacter pylori. glycoprotein 3-alpha-L-fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc alpha 1,3-fucosyltransferase; EC 2.4.1.214; Glycoprotein 3-alpha-L-fucosyltransferase. Cat No: NATE-1483.
D-arabinose isomerase
Requires a divalent metal ion (the enzyme from the bacterium Escherichia coli prefers Mn2+). The enzyme binds the closed form of the sugar and catalyses ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene-diol mechanism. The enzyme catalyses the aldose-ketose isomerization of several sugars. Most enzymes also catalyse the reaction of EC 5.3.1.25, L-fucose isomerase. The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4, L-arabinose isomerase. Group: Enzymes. Synonyms: D-arabinose(L-fucose) isomerase; L-fucose isomerase; D-arabinose ketol-isomerase; arabinose isomerase (misleading). Enzyme Commission Number: EC 5.3.1.3. CAS No. 9023-81-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5469; D-arabinose isomerase; EC 5.3.1.3; 9023-81-8; D-arabinose(L-fucose) isomerase; L-fucose isomerase; D-arabinose ketol-isomerase; arabinose isomerase (misleading). Cat No: EXWM-5469.
D-(+)-Fucose
D-(+)-Fucose is a nonmetabolizable analogue of l-arabinose. D-(+)-Fucose prevents growth of Escherichia coli B/r on a mineral salts medium plus l-arabinose by inhibiting induction of the l-arabinose operon [1]. D-fucose is a potent inducer of beta-methylgalactoside permease (MGP) [2]. Uses: Scientific research. Group: Natural products. CAS No. 3615-37-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N5102.
D-threo-aldose 1-dehydrogenase
Acts on L-fucose, D-arabinose and L-xylose; the animal enzyme was also shown to act on L-arabinose, and the enzyme from Pseudomonas caryophylli on L-glucose. Group: Enzymes. Synonyms: L-fucose dehydrogenase; (2S,3R)-aldose dehydrogenase; dehydrogenase, L-fucose; L-fucose (D-arabinose) dehydrogenase. Enzyme Commission Number: EC 1.1.1.122. CAS No. 9082-70-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0026; D-threo-aldose 1-dehydrogenase; EC 1.1.1.122; 9082-70-6; L-fucose dehydrogenase; (2S,3R)-aldose dehydrogenase; dehydrogenase, L-fucose; L-fucose (D-arabinose) dehydrogenase. Cat No: EXWM-0026.
Fucoidan
Fucoidan is a polysaccharide rich in diverse bioactive compounds found in brown marine algae (Phaeophyta, typically Ascophyllum nodosum and Laminaria digitata). It has anticoagulant activity and consists mainly of α(1-4) and α(1-2) linked L-fucose sulfates, although galactose is also present, with many variations of the basic structure found in different species of Phaeophyta. Esteemed for its exceptional immunomodulatory and anti-inflammatory attributes, fucoidan has been explored for its potential against formidable adversaries like cancer, viral infections, cardiovascular diseases, and inflammatory conditions. Synonyms: Sulfated L-fucan; DH 0201; Fuco'min; Fuco'min; Fucoidin; Fucoidine; LF 0902; Limuveil HV; Nemacystus mucilage; Sea Alga-F; Fucoidan - Ascophyllum nodosum. CAS No. 9072-19-9. Molecular formula: (C6H9O3SO3)n.
fucokinase
Requires a divalent cation for activity, with Mg2+ and Fe2+ giving rise to the highest enzyme activity. Forms part of a salvage pathway for reutilization of L-fucose. Can also phosphorylate D-arabinose, but more slowly. Group: Enzymes. Synonyms: fucokinase (phosphorylating); fucose kinase; L-fucose kinase; L-fucokinase; ATP:6-deoxy-L-galactose 1-phosphotransferase; ATP:L-fucose 1-phosphotransferase. Enzyme Commission Number: EC 2.7.1.52. CAS No. 37278-00-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3083; fucokinase; EC 2.7.1.52; 37278-00-5; fucokinase (phosphorylating); fucose kinase; L-fucose kinase; L-fucokinase; ATP:6-deoxy-L-galactose 1-phosphotransferase; ATP:L-fucose 1-phosphotransferase. Cat No: EXWM-3083.
(-)-Fucose
(-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Desoxygalactose; L-(-)-Fucose; L-Galactomethylose. CAS No. 2438-80-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N1480.
fucose-1-phosphate guanylyltransferase
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GTP:beta-L-fucose-1-phosphate guanylyltransferase. Other names in common use include GDP fucose pyrophosphorylase, guanosine diphosphate L-fucose pyrophosphorylase, GDP-L-fucose pyrophosphorylase, GDP-fucose pyrophosphorylase, and GTP:L-fucose-1-phosphate guanylyltransferase. This enzyme participates in fructose and mannose metabolism. Group: Enzymes. Synonyms: GDP fucose pyrophosphorylase; guanosine diphosphate L-fucose pyrophosphorylase; GDP-L-fucose pyrophosphorylase; GDP-fucose pyrophosphorylase; GTP:L-fucose-1-phosphate guanylyltransferase. Enzyme Commission Number: EC 2.7.7.30. CAS No. 9033-14-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3241; fucose-1-phosphate guanylyltransferase; EC 2.7.7.30; 9033-14-1; GDP fucose pyrophosphorylase; guanosine diphosphate L-fucose pyrophosphorylase; GDP-L-fucose pyrophosphorylase; GDP-fucose pyrophosphorylase; GTP:L-fucose-1-phosphate guanylyltransferase. Cat No: EXWM-3241.
galactoside 2-α-L-fucosyltransferase
Free lactose can act as acceptor. Normally acts on a glycoconjugate where R (see reaction) is a glycoprotein or glycolipid. The action on glycolipid was previously listed as EC 2.4.1.89. Group: Enzymes. Synonyms: blood group H α-2-fucosyltransferase; guanosine diphosphofucose-galactoside 2-L-fucosyltransferase; α-(1?2)-L-fucosyltransferase; α-2-fucosyltransferase; α-2-L-fucosyltransferase; blood-group substance H-dependent fucosyltransferase; guanosine diphosphofucose-glycoprotein 2-α-fucosyltransferase; guanosine diphosphofucose-lactose fucosyltransferase; GDP fuco. Enzyme Commission Number: EC 2.4.1.69. CAS No. 56093-23-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2612; galactoside 2-α-L-fucosyltransferase; EC 2.4.1.69; 56093-23-3; blood group H α-2-fucosyltransferase; guanosine diphosphofucose-galactoside 2-L-fucosyltransferase; α-(1?2)-L-fucosyltransferase; α-2-fucosyltransferase; α-2-L-fucosyltransferase; blood-group substance H-dependent fucosyltransferase; guanosine diphosphofucose-glycoprotein 2-α-fucosyltransferase; guanosine diphosphofucose-lactose fucosyltransferase; GDP fucose-lactose fucosyltransferase; guanosine diphospho-L-fucose-lactose fucosyltransferase; guanosine
GDP-2F-Fuc ammonium salt
A competitive inhibitor of fucosyltransferases FUT3, FUT5, FUT6 and FUT7 with Ki values in low micromolar range. This fluorinated GDP-fucose analog inhibits oligosaccharide core fucosylation of N-linked glycans in animal and plant cells. Synonyms: GDP-2-deoxy-2-fluoro-L-fucose ammonium salt. Molecular formula: C16H30FN7O14P2. Mole weight: 625.39.
GDP-mannose 4,6-dehydratase
The bacterial enzyme requires bound NAD+. This enzyme forms the first step in the biosynthesis of GDP-α-D-rhamnose and GDP-β-L-fucose. In Aneurinibacillus thermoaerophilus L420-91T, this enzyme acts as a bifunctional enzyme, catalysing the above reaction as well as the reaction catalysed by EC 1.1.1.281, GDP-4-dehydro-6-deoxy-D-mannose reductase. Belongs to the short-chain dehydrogenase/reductase enzyme family, having homologous structures and a conserved catalytic triad of Lys, Tyr and Ser/Thr residues. Group: Enzymes. Synonyms: guanosine 5'-diphosphate-D-mannose oxidoreductase; guanosine diphosphomannose oxidoreductase; guanosine diphosphomannose 4,6-dehydratase; GDP-D-mannose dehydratase; GDP-D-mannose 4,6-dehydratase; Gmd; GDP-mannose 4,6-hydro-lyase; GDP-mannose 4,6-hydro-. Enzyme Commission Number: EC 4.2.1.47. CAS No. 37211-59-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5036; GDP-mannose 4,6-dehydratase; EC 4.2.1.47; 37211-59-9; guanosine 5'-diphosphate-D-mannose oxidoreductase; guanosine diphosphomannose oxidoreductase; guanosine diphosphomannose 4,6-dehydratase; GDP-D-mannose dehydratase; GDP-D-mannose 4,6-dehydratase; Gmd; GDP-mannose 4,6-hydro-lyase; GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming). Cat No: EXWM-5036.
glycoprotein 3-α-L-fucosyltransferase
Requires Mn2+. The enzyme transfers to N-linked oligosaccharide structures (N-glycans), generally with a specificity for N-glycans with one unsubstituted non-reducing terminal GlcNAc residue. This enzyme catalyses a reaction similar to that of EC 2.4.1.68, glycoprotein 6-α-L-fucosyltransferase, but transferring the L-fucosyl group from GDP-β-L-fucose to form an α1,3-linkage rather than an α1,6-linkage. The N-glycan products of this enzyme are present in plants, insects and some other invertebrates (e.g., Schistosoma, Haemonchus, Lymnaea). Group: Enzymes. Synonyms: GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc α1,3-fucosyltransferase; GDP-fucose:β-N-acetylglucosamine (Fuc to (Fucα1?6GlcNAc)-Asn-peptide) α1?3-fucosyltransferase; GDP-L-fucose:glycoprotein (L-fucose to asparagine-. Enzyme Commission Number: EC 2.4.1.214. CAS No. 68247-53-0. α-fucosyltransferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2442; glycoprotein 3-α-L-fucosyltransferase; EC 2.4.1.214; 68247-53-0; GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1,3-fucosyltransferase; GDP-L-Fuc:Asn-linked GlcNAc α1,3-fucosyltransferase; GDP-fucose:β-N-acetylglucosamin
glycoprotein 6-α-L-fucosyltransferase
This enzyme catalyses a reaction similar to that of EC 2.4.1.214, glycoprotein 3-α-L-fucosyltransferase, but transfers the L-fucosyl group from GDP-β-L-fucose to form an α1,6-linkage rather than an α1,3-linkage. Group: Enzymes. Synonyms: GDP-fucose-glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1?6fucosyltransferase; GDP-L-fucose-glycoprotein fucosyltransferase; glycoprotein fucosyltransferase; guanosine diphosphofucose-glycoprotein fucosyltransferase; GDP-L-fucose:glycoprotein (L-fucose to asparagine-link. Enzyme Commission Number: EC 2.4.1.68. CAS No. 9033-8-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2611; glycoprotein 6-α-L-fucosyltransferase; EC 2.4.1.68; 9033-08-3; GDP-fucose-glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-β-D-glucosaminide α1?6fucosyltransferase; GDP-L-fucose-glycoprotein fucosyltransferase; glycoprotein fucosyltransferase; guanosine diphosphofucose-glycoprotein fucosyltransferase; GDP-L-fucose:glycoprotein (L-fucose to asparagine-linked N-acetylglucosamine of 4-N-{N-acetyl-β-D-glucosaminyl-(1?2)-α-D-mannosyl-(1?3)-[N-acetyl-β-D-glucosaminyl-(1?2)-α-D-mannosyl-(1?6)]-β-D-mannosyl-(1?4)-N-acetyl-β-D-glucosaminyl-
Guanosine 5'-Monophosphate Ester 6-Deoxytalose Sodium Salt
Guanosine 5'-Monophosphate Ester 6-Deoxytalose Sodium Salt is used in the synthetic preparation of nucleoside monophosphate sugars such as GMP-Fucose. Synonyms: 5'-Guanylic Acid Mono(6-deoxy-α-L-galactopyranosyl) Ester Sodium Salt. Molecular formula: C16H23N5NaO12P. Mole weight: 531.34.
Native Bovine α-L-Fucosidase
In enzymology, an alpha-L-fucosidase (EC 3.2.1.51) is an enzyme that catalyzes the chemical reaction:an alpha-L-fucoside + H2O<-> L-fucose + an alcohol. Thus, the two substrates of this enzyme are alpha-L-fucoside and H2O, whereas its two products are L-fucose and alcohol. This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O-and S-glycosyl compounds. This enzyme participates in n-glycan degradation and glycan structures-degradation. Group: Enzymes. Synonyms: α-L-Fucosidase; EC 3.2.1.51; α-fucosidase. Enzyme Commission Number: EC 3.2.1.51. CAS No. 9037-65-4. FUCA. Activity: > 2.0 units/mg protein (biuret). Storage: 2-8°C. Form: ammonium sulfate suspension. Suspension in 3.2 M (NH4)2SO4, 10 mM NaH2PO4 10 mM Citrate, pH 6.0. Source: Bovine kidney. Species: Bovine. α-L-Fucosidase; EC 3.2.1.51; α-fucosidase. Cat No: NATE-0266.
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