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| Product | Description | |
|---|---|---|
| L-Iduronic acid | L-Iduronic acid, a highly significant compound prevalent in the biomedical field, finds extensive application. In the pursuit of combating diverse ailments like cancer, cardiovascular diseases, and inflammatory disorders, this compound serves as an indispensable component for drug synthesis. Its remarkable attributes render it crucial for formulating drug delivery systems that augment therapeutic efficacy. Synonyms: Iduronic acid, L-; Aldehydo-L-iduronic acid. Grades: ≥95%. CAS No. 2073-35-0. Molecular formula: C6H10O7. Mole weight: 194.14. |  |
| L-Iduronic acid-1,6-13C2 | L-Iduronic acid-1,6-13C2 is a valuable biochemical utilized in the biomedical industry for its role in synthesizing drugs used to study diseases related to abnormal glycosaminoglycan metabolism. Its isotopic label, 13C2, aids in research and drug development, facilitating accurate tracing and analysis of metabolic pathways. Molecular formula: 13C2C4H10O7. Mole weight: 2523.81. | |
| L-Iduronic acid sodium salt | L-Iduronic acid sodium salt, a highly significant compound prevalent in the biomedical field, finds extensive application. In the pursuit of combating diverse ailments like cancer, cardiovascular diseases, and inflammatory disorders, this compound serves as an indispensable component for drug synthesis. Its remarkable attributes render it crucial for formulating drug delivery systems that augment therapeutic efficacy. Uses: A constituent of certain mucopolysaccharides. Synonyms: Sodium L-iduronate; L-Iduronic acid, monosodium salt; (2R,3S,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexanoate sodium salt. Grades: ≥95%. CAS No. 61199-83-5. Molecular formula: C6H9NaO7. Mole weight: 216.12. | |
| 4-Methylumbelliferyl a-L-idopyranosiduronic acid sodium salt | It is a fluorogenic substrate in the assay of a-L-Iduronidase. Synonyms: Sodium (4-methylumbelliferyl a-L-idopyranosid)uronate; 4-Methylumbelliferyl α-L-Iduronic Acid, Sodium Salt; Sodium 4-methyl-2-oxo-2H-chromen-7-yl α-L-idopyranosiduronate; 2H-1-Benzopyran-2-one, 7-(α-L-idopyranuronosyloxy)-4-methyl-, sodium salt (1:1). Grades: ≥95%. CAS No. 89157-94-8. Molecular formula: C16H15NaO9. Mole weight: 374.27. | |
| α-L-Iduronidase from Human, Recombinant | This enzyme catalyses the hydrolysis of unsulfated α-L-iduronosidic linkages in dermatan sulfate. In lysosomal degradation process α-L-Iduronidase plays a crucial role. It hydrolyzes the non-reducing terminal α-L-iduronic acid residues in GAGs, including dermatan sulfate and heparan sulfate. It is involved in the degeneration of glycosaminoglycans such as dermatan sulfate and heparan sulfate. It is found in the lysosomes of cells. Applications: Α-l-iduronidase may be used for leukocyte assay in the study of a-l-iduronidase deficiency in new born. Group: Enzymes. Synonyms: Iduronidase; EC 3.2.1.76; L-iduronidase; alpha-L-iduronidase); glycosaminoglycan alpha-L-iduronohydrolase; IDUA; α-L-Iduronidase. Enzyme Commission Number: EC 3.2.1.76. IDUA. Mole weight: 71 kDa. Activity: >7,500 units/μg protein. Storage: Store at -20°C. Form: Supplied as a solution in 40 mM sodium acetate , 400 mM NaCl and 20% (v/v) glycerol, pH 5.0. Source: Mouse NSO cells. Species: Human. Iduronidase; EC 3.2.1.76; L-iduronidase; alpha-L-iduronidase); glycosaminoglycan alpha-L-iduronohydrolase; IDUA; α-L-Iduronidase. Cat No: NATE-0930. |  |
| unsaturated chondroitin disaccharide hydrolase | The enzyme releases 4-deoxy-4,5-didehydro D-glucuronic acid or 4-deoxy-4,5-didehydro L-iduronic acid from chondroitin disaccharides, hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1?3) and (1?4) bonds. It prefers the sulfated disaccharides to the unsulfated disaccharides. Group: Enzymes. Synonyms: UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Enzyme Commission Number: EC 3.2.1.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3864; unsaturated chondroitin disaccharide hydrolase; EC 3.2.1.180; UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Cat No: EXWM-3864. | |
| 4-Methylumbelliferyl 1,2-O-(Dibutylsulfane)-α-L-Idopyranuronic Acid Methyl Ester | As an intermediate used in the synthesis of 4-Methylumbelliferyl α-L-Idopyranosiduronic Acid 2-Sulfate Disodium Salt, 4-Methylumbelliferyl 1,2-O-(dibutylsulfane)-α-L-Idopyranuronic Acid Methyl Ester is a fluorogenic substrate in the assay of α-L-Iduronidase. A fluorimetric enzyme assay for the diagnosis of MPS II (Hunter disease). Molecular formula: C25H34O9S. Mole weight: 510.6. | |
| 4-Methylumbelliferyl a-L-idopyranosiduronic acid 2-sulphate disodium salt | 4-Methylumbelliferyl-α-L-iduronide 2-sulfate (4-MU-α-IdoA 2-sulfate) is a fluorogenic substrate for α-L-iduronidase that has been used in an assay to detect Hurler syndrome. It is also a substrate for iduronate-2-sulfatase that can be used for diagnosis of Hunter disease (MPS II). Synonyms: 4-Methylumbelliferyl-α-L-Idopyranosiduronic Acid 2-sulfate disodium salt; 4-MU-α-IdoA 2-sulfate disodium salt; (2R,3S,4S,5R,6S)-3,4-dihydroxy-6-((4-methyl-2-oxo-2H-chromen-7-yl)oxy)-5-(sulfonatooxy)tetrahydro-2H-pyran-2-carboxylate disodium salt. Grades: ≥98%. CAS No. 1045020-74-3. Molecular formula: C16H14Na2O12S. Mole weight: 476.3. | |
| 4-Methylumbelliferyl a-L-iduronide | It is a fluorogenic substrate for α-L-iduronidase. Synonyms: 4-methyl-2-oxo-2H-1-benzopyran-7-yl α-L-idopyranosiduronic acid; 4-Methylumbelliferyl-α-L-Idopyranosiduronic Acid; 4-MU-α-IdoA; MU-α-IdoA?. Grades: ≥90%. CAS No. 66966-09-4. Molecular formula: C16H16O9. Mole weight: 352.29. | |
| L-iduronidase | Iduronidase (EC 3.2.1.76, L-iduronidase, alpha-L-iduronidase, laronidase) is an enzyme with the systematic name glycosaminoglycan alpha-L-iduronohydrolase. This enzyme catalyses the hydrolysis of unsulfated alpha-L-iduronosidic linkages in dermatan sulfate.It is a glycoprotein enzyme found in the lysosomes of cells. It is involved in the degeneration of glycosaminoglycans such as dermatan sulfate and heparan sulfate. The enzyme acts by hydrolyzing the terminal alpha-L-induronic acid residues of these molecules, degrading them. The protein is reported as having a mass of approximately 83 kilodaltons. Group: Enzymes. Synonyms: α-L-iduronidase. Enzyme Commission Number: EC 3.2.1.76. CAS No. 9073-56-7. IDUA. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3940; L-iduronidase; EC 3.2.1.76; 9073-56-7; α-L-iduronidase. Cat No: EXWM-3940. | |
| Native Proteus vulgaris Chondroitinase ABC | Chondroitinase ABC catalyzes the eliminative degradation of polysaccharides containing (1-4)-β-D-hexosaminyl and (1-3)-β-D-glucuronosyl or (1-3)-α-L-iduronosyl linkages to disaccharides containing 4-deoxy-β-D-gluc-4-enuronosyl groups. It acts on chondroitin 4-sulfate, chondroitin 6-sulfate, and dermatan sulfate, and acts slowly on hyaluronate. The molecular weight is found to be approximately 120 kDa with 2 non-identical subunits of molecular masses 86 kDa and 32 kDa. The pH optimum is found to be 8.0 with chondroitin sulfate and 6.8 with hyaluronic acid and tempeRature optimum is 37°C. 1 mM Zn2+ acts as an inhibitor, while 0.05 M acetate is an activ...BC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; 9024-13-9. Enzyme Commission Number: EC 4.2.2.4. CAS No. 9024-13-9. Chondroitinase ABC. Activity: 50-250 units/mg protein (using chondroitin sulfate C as substrate); 0.3-3 units/mg solid (using chondroitin sulfate C as substrate). Storage: -20°C. Form: lyophilized powder. Source: Proteus vulgaris. EC 4.2.2.4, chondroitinase; chondroitin ABC eliminase; chondroitinase ABC; chondroitin ABC lyase; chondroitin sulfate ABC lyase; ChS ABC lyase; chondroitin sulfate ABC endoeliminase; chondroitin sulfate ABC endolyase; ChS ABC lyase I; 9024-13-9. Cat No: NATE-0131. | |
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